S. Wonnacott

发表

International Union of Pharmacology. XX. Current status of the nomenclature for nicotinic acetylcholine receptors and their subunits.

J P Changeux, E X Albuquerque, A. C. Collins, 1999, Pharmacological reviews.

Subtype-selective nicotinic agonists enhance olfactory working memory in normal rats: A novel use of the odour span task

S. Wonnacott, M. Shoaib, S. Rushforth, 2010, Neuroscience Letters.

Differential effects of acute and chronic nicotine on Elk-1 in rat hippocampus

I. Jones, S. Wonnacott, J. Barik, 2007, Neuroreport.

α6β2* and α4β2* Nicotinic Acetylcholine Receptors As Drug Targets for Parkinson's Disease

M. Quik, S. Wonnacott, 2011, Pharmacological Reviews.

Nicotinic Acetylcholine Receptors As Drug Targets for Parkinson ’ s Disease

M. Quik, S. Wonnacott, 2011 .

Nicotinic acetylcholine receptors

S. Wonnacott, N. Millar, S. Tzartos, 2018, British journal of pharmacology.

Identification of the Initial Steps in Signal Transduction in the α4β2 Nicotinic Receptor: Insights from Equilibrium and Nonequilibrium Simulations.

R. Sessions, A. Mulholland, S. Wonnacott, 2019, Structure.

Involvement of protein kinase C in the presynaptic nicotinic modulation of [3H]‐dopamine release from rat striatal synaptosomes

S. Wonnacott, L. Soliakov, Susan Wonnacott, 2001, British journal of pharmacology.

[3H]-Methyllycaconitine: a high affinity radioligand that labels invertebrate nicotinic acetylcholine receptors.

S. Reynolds, B. Potter, A. Wolstenholme, 2001, Insect biochemistry and molecular biology.

Presynaptic α7 and non-α7 nicotinic acetylcholine receptors modulate [3H]d-aspartate release from rat frontal cortex in vitro

I. Jones, S. Wonnacott, S. Rousseau, 2005, Neuropharmacology.

Presynaptic alpha7 and non-alpha7 nicotinic acetylcholine receptors modulate [3H]d-aspartate release from rat frontal cortex in vitro.

I. Jones, S. Wonnacott, S. Rousseau, 2005, Neuropharmacology.

Nicotinic acetylcholine receptors differentially regulate phosphorylation of dopamine target cell proteins in the rat prefrontal cortex

S. Wonnacott, J. Hockley, P. D. Livingstone, 2009 .

Is a Potent and Selective Antagonist at Rat and Human Native 7 Nicotinic Acetylcholine Receptors

S. Wonnacott, J. McIntosh, P. Whiteaker, 2008 .

Neuroprotection by nicotine against hypoxia-induced apoptosis in cortical cultures involves activation of multiple nicotinic acetylcholine receptor subtypes

S. Wonnacott, S. Barns, F. Dajas-Bailador, 2003, Molecular and Cellular Neuroscience.

Ethyl-for-methyl substitution enhances the subtype specificity of mecamylamine analogues.

S. Wonnacott, D. Mangan, I. Bermúdez, 2019, Organic & biomolecular chemistry.

A new synthesis and preliminary evaluation of some analogues of mecamylamine - a compound with anti-addiction properties.

S. Wonnacott, D. Mangan, I. Bermúdez, 2016, Organic & biomolecular chemistry.

Methyllycaconitine is a potent antagonist of alpha-conotoxin-MII-sensitive presynaptic nicotinic acetylcholine receptors in rat striatum.

A. C. Collins, A. Collins, M. Marks, 2002, The Journal of pharmacology and experimental therapeutics.

Agonist pharmacology of the neuronal α7 nicotinic receptor expressed in Xenopus oocytes

M. Amar, G. Lunt, S. Wonnacott, 1993 .

6-Substituted 2-azabicyclo[2.2.1]hept-5-enes by nitrogen-directed radical rearrangement: synthesis of an epibatidine analogue with high binding affinity at the nicotinic acetylcholine receptor

A. Dickenson, S. Wonnacott, K. Carpenter, 2001 .

Evidence for Functional Activity of Up‐Regulated Nicotine Binding Sites in Rat Striatal Synaptosomes

S. Wonnacott, P. Rowell, Peter P. Rowell, 1990, Journal of neurochemistry.

Agonist pharmacology of the neuronal alpha 7 nicotinic receptor expressed in Xenopus oocytes.

M. Amar, S. Wonnacott, P. Thomas, 1993, FEBS letters.

α-Bungarotoxin binding sites in rat hippocampal and cortical cultures: initial characterisation, colocalisation with α7 subunits and up-regulation by chronic nicotine treatment

J. Lindstrom, S. Wonnacott, G. Barrantes, 1995, Brain Research.

Neurotoxicity induced by okadaic acid in the human neuroblastoma SH-SY5Y line can be differentially prevented by α7 and β2* nicotinic stimulation.

J. Ávila, Manuela G. López, S. Wonnacott, 2011, Toxicological sciences : an official journal of the Society of Toxicology.

αBungarotoxin and Presynaptic Nicotinic Receptors: Functional Studies

G. Lunt, E. Albuquerque, S. Wonnacott, 1988 .

Brain Nicotine Binding Sites

S. Wonnacott, 1987, Human toxicology.

The allosteric potentiation of nicotinic acetylcholine receptors by galantamine is transduced into cellular responses in neurons: Ca2+ signals and neurotransmitter release.

S. Wonnacott, F. Dajas-Bailador, Kaisa Heimala, 2003, Molecular pharmacology.

6-Hydroxydopamine-induced Apoptosis Is Mediated via Extracellular Auto-oxidation and Caspase 3-dependent Activation of Protein Kinase Cδ*

M. O'Neill, S. Wonnacott, Katharine Hanrott, 2006, Journal of Biological Chemistry.

Nicotinic acetylcholine receptors (nACh) in GtoPdb v.2021.3

M. Marks, C. Gotti, S. Wonnacott, 2021, IUPHAR/BPS Guide to Pharmacology CITE.

Nicotinic pharmacology of anatoxin analogs. II. Side chain structure-activity relationships at neuronal nicotinic ligand binding sites.

E. Albuquerque, S. Wonnacott, H. Rapoport, 1991, The Journal of pharmacology and experimental therapeutics.

Glutamate-Gated Chloride Channels of Haemonchus contortus Restore Drug Sensitivity to Ivermectin Resistant Caenorhabditis elegans

S. Buckingham, D. Sattelle, A. Wolstenholme, 2011, PloS one.

Alpha bungarotoxin-1.4nm gold: a novel conjugate for visualising the precise subcellular distribution of alpha 7* nicotinic acetylcholine receptors

I. Jones, M. O'Neill, S. Wonnacott, 2004, Journal of Neuroscience Methods.

Anatoxin-a is a potent agonist of the nicotinic acetylcholine receptor of bovine adrenal chromaffin cells.

S. Wonnacott, P. Brough, T. Gallagher, 1995, European journal of pharmacology.

[3H](-)nicotine binding sites in fetal human brain

N. Cairns, S. Wonnacott, 1988, Brain Research.

Presynaptic nicotinic acetylcholine receptors: subtypes mediating neurotransmitter release

I. Jones, S. Wonnacott, Bradly Alicea, 2001 .

Agonist-induced up-regulation of alpha4beta2 nicotinic acetylcholine receptors in M10 cells: pharmacological and spatial definition.

S. Wonnacott, P. Whiteaker, C. Sharples, 1998, Molecular pharmacology.

Agonist-Induced Up-Regulation of a 4 b 2 Nicotinic Acetylcholine Receptors in M 10 Cells : Pharmacological and Spatial Definition

S. Wonnacott, P. Whiteaker, C. Sharples, 1998 .

Methyllycaconitine: a selective probe for neuronal alpha-bungarotoxin binding sites.

G. Lunt, S. Wonnacott, V. Cockcroft, 1990, FEBS letters.

Nicotinic pharmacology of anatoxin analogs. I. Side chain structure-activity relationships at peripheral agonist and noncompetitive antagonist sites.

E. Albuquerque, S. Wonnacott, R. Aronstam, 1991, The Journal of pharmacology and experimental therapeutics.

A Conserved Arginine with Non-Conserved Function is a Key Determinant of Agonist Selectivity in Alpha7 Nicotinic Acetylcholine Receptors

R. Sessions, C. Bouzat, A. Mulholland, 2020, Biophysical Journal.

Cellular responses to nicotinic receptor activation are decreased after prolonged exposure to galantamine in human neuroblastoma cells

S. Wonnacott, J. Barik, F. Dajas-Bailador, 2005, British journal of pharmacology.

(+)‐Anatoxin‐a Is a Potent Agonist at Neuronal Nicotinic Acetylcholine Receptors

M. Amar, E. Albuquerque, P. Whiting, 1993, Journal of neurochemistry.

Comparison of the effects of bupropion and nicotine on locomotor activation and dopamine release in vivo.

S. Wonnacott, D. Heal, H. Rowley, 2007, Biochemical pharmacology.

The synthesis and nicotinic binding activity of (+/-)-epiquinamide and (+/-)-C(1)-epiepiquinamide.

S. Wonnacott, D. Gray, T. Gallagher, 2006, Bioorganic & medicinal chemistry letters.

C3-halogenation of cytisine generates potent and efficacious nicotinic receptor agonists.

S. Wonnacott, J. Barik, P. Iturriaga-Vásquez, 2006, European journal of pharmacology.

Increase in locomotor activity after acute administration of the nicotinic receptor agonist 3-bromocytisine in rats.

S. Wonnacott, B. Cassels, C. Scorza, 2010, European journal of pharmacology.

Upregulation of nicotinic receptors following continuous infusion of nicotine is brain-region-specific

A. Drasdo, S. Wonnacott, K. McCrea, 1993, Brain Research.

Antianginal and anti-ischaemic efficacy of tedisamil, a potassium channel blocker

K. Fox, S. Wonnacott, A. Sachse, 2000, Heart.

Functional responses and subunit composition of presynaptic nicotinic receptor subtypes explored using the novel agonist 5-iodo-A-85380

S. Wonnacott, A. Mogg, I. Pullar, 2004, Neuropharmacology.

Differential effects of chronic drug treatment on α3* and α7 nicotinic receptor binding sites, in hippocampal neurones and SH‐SY5Y cells

S. Wonnacott, A. Rogers, D. L. Ridley, 2001 .

Dierential eects of chronic drug treatment on a3* and a7 nicotinic receptor binding sites, in hippocampal neurones and SH-SY5Y cells

S. Wonnacott, A. Rogers, D. L. Ridley, 2001 .

An autoradiographic study of the distribution of binding sites for the novel α7‐selective nicotinic radioligand [3H]‐methyllycaconitine in the mouse brain

A. C. Collins, A. Collins, B. Potter, 1999, The European journal of neuroscience.

Locomotor activation and dopamine release produced by nicotine and isoarecolone in rats

I. Stolerman, S. Wonnacott, P. Whiteaker, 1995, British journal of pharmacology.

Regulation of the Release of Dopamine from Striatal Synaptosomes by Nicotinic Acetylcholine Receptors

G. Lunt, S. Wonnacott, R. Harrison, 1986 .

A nicotinic acetylcholine receptor subunit from insect brain forms a non-desensitising homo-oligomeric nicotinic acetylcholine receptor when expressed in Xenopus oocytes

M. Amar, G. Lunt, S. Wonnacott, 1995, Neuroscience Letters.

Differential Inhibition by α‐Conotoxin‐MII of the Nicotinic Stimulation of [3H]Dopamine Release from Rat Striatal Synaptosomes and Slices

S. Wonnacott, C. Luetje, L. Soliakov, 1998, Journal of neurochemistry.

Interrelationship of carbohydrate and the alpha-toxin binding site on the acetylcholine receptor from Torpedo marmorata.

G. Lunt, S. Wonnacott, R. Harrison, 1980, Life sciences.

Pharmacological differences between rat frontal cortex and hippocampus in the nicotinic modulation of noradrenaline release implicate distinct receptor subtypes.

S. Wonnacott, D. Heal, A. Kennett, 2012, Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco.

The alpha7 nicotinic acetylcholine receptor subtype mediates nicotine protection against NMDA excitotoxicity in primary hippocampal cultures through a Ca(2+) dependent mechanism.

P. A. Lima, S. Wonnacott, F. Dajas-Bailador, 2000, Neuropharmacology.

Synthesis and nicotinic binding of novel phenyl derivatives of UB-165. Identifying factors associated with alpha7 selectivity.

S. Wonnacott, T. Gallagher, J. Large, 2003, Bioorganic & medicinal chemistry letters.

Homoanatoxin: a potent analogue of anatoxin-A.

E. Albuquerque, T. Gallagher, S. Wonnacott, 1992, Biochemical pharmacology.

Immunological cross-reactivity between the α-bungarotoxin-binding component from rat brain and nicotinic acetylcholine receptor

G. Lunt, S. Wonnacott, R. Harrison, 1982, Journal of Neuroimmunology.

Tetrodotoxin-sensitivity of nicotine-evoked dopamine release from rat striatum

S. Wonnacott, L. Soliakov, P. Redfern, 1996, Neuropharmacology.

Presynaptic Nicotinic Autoreceptors and Heteroreceptors in the CNS

S. Wonnacott, P. Whiteaker, L. Soliakov, 1995 .

Isolation of Hippocampal Synaptosomes on Percoll Gradients: Cholinergic Markers and Ligand Binding Sites

S. Wonnacott, P. Dunkley, B. Thorne, 1991, Journal of neurochemistry.

Presynaptic Actions of Nicotine in the CNS

A. Drasdo, S. Wonnacott, 1991 .

The neurotoxin histrionicotoxin interacts with the putative ion channel of the nicotinic acetylcholine receptors in the central nervous system

G. Lunt, E. Albuquerque, S. Wonnacott, 1987, FEBS letters.

Anatoxin-a-evoked [3H]dopamine release from rat striatal synaptosomes

S. Wonnacott, T. Gallagher, L. Soliakov, 1995, Neuropharmacology.

Structural modification of anatoxin-a. Synthesis of model affinity ligands for the nicotinic acetylcholine receptor

S. Wonnacott, P. Thompson, T. Gallagher, 1991 .

Neosurugatoxin blocks nicotinic acetylcholine receptors in the brain

G. Lunt, S. Wonnacott, R. Harrison, 1985, Neurochemistry International.

Unlocking Nicotinic Selectivity via Direct C‒H Functionalization of (−)-Cytisine

R. Sessions, K. Ranaghan, A. Mulholland, 2018, Chem.

Synthesis and pharmacological characterization of novel analogues of the nicotinic acetylcholine receptor agonist (+/-)-UB-165.

S. Wonnacott, N. Millar, T. Gallagher, 2002, Journal of medicinal chemistry.

Rapid and efficient isolation of the nicotinic receptor antagonist methyllycaconitine from delphinium:assignment of the methylsuccinimide absolute stereochemistry as S

B. Potter, I. S. Blagbrough, S. Wonnacott, 1994 .

Methyllycaconitine: a selective probe for neuronal α‐bungarotoxin binding sites

G. Lunt, S. Wonnacott, V. Cockcroft, 1990 .

Nicotine activates the extracellular signal‐regulated kinase 1/2 via the α7 nicotinic acetylcholine receptor and protein kinase A, in SH‐SY5Y cells and hippocampal neurones

S. Wonnacott, F. Dajas-Bailador, L. Soliakov, 2002, Journal of neurochemistry.

Blockade of nicotinic currents in hippocampal neurons defines methyllycaconitine as a potent and specific receptor antagonist.

E X Albuquerque, M Alkondon, E F Pereira, 1992, Molecular pharmacology.

Methyllycaconitine and (+)‐anatoxin‐a differentiate between nicotinic receptors in vertebrate and invertebrate nervous systems

G. Lunt, E. Albuquerque, S. Wonnacott, 1988, FEBS letters.

Conversion of the sodium channel activator aconitine into a potent α7‐selective nicotinic ligand

B. Potter, I. S. Blagbrough, S. Wonnacott, 1995, FEBS letters.

The Chemistry and Pharmacology of Anatoxin-a and Related Homotropanes with respect to Nicotinic Acetylcholine Receptors

S. Wonnacott, T. Gallagher, 2006, Marine Drugs.

UB-165: A Novel Nicotinic Agonist with Subtype Selectivity Implicates the α4β2* Subtype in the Modulation of Dopamine Release from Rat Striatal Synaptosomes

A. C. Collins, A. Collins, M. Marks, 2000, The Journal of Neuroscience.

Synthesis of UB-165: A novel nicotinic ligand and anatoxin-a/epibatidine hybrid

S. Wonnacott, T. Gallagher, E. Wright, 1997 .

Synthesis of two fluoro analogues of the nicotinic acetylcholine receptor agonist UB-165.

S. Wonnacott, T. Gallagher, A. Sutherland, 2003, The Journal of organic chemistry.

The relevance of receptor binding studies to tobacco research.

S. Wonnacott, 1991, British journal of addiction.

Nicotinic acetylcholine receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

M. Marks, C. Gotti, S. Wonnacott, 2019, IUPHAR/BPS Guide to Pharmacology CITE.

Presynaptic localisation of the nicotinic acetylcholine receptor β2 subunit immunoreactivity in rat nigrostriatal dopaminergic neurones

J. Bolam, I. Jones, S. Wonnacott, 2001, The Journal of comparative neurology.

The α7 nicotinic acetylcholine receptor subtype mediates nicotine protection against NMDA excitotoxicity in primary hippocampal cultures through a Ca2+ dependent mechanism

P. A. Lima, S. Wonnacott, F. Dajas-Bailador, 2000, Neuropharmacology.

Depolarisation‐Induced Release of ATP from Cortical Synaptosomes Is Not Associated with Acetylcholine Release

S. Wonnacott, P. Potter, T. White, 1980, Journal of neurochemistry.

Subcellular fractionation and distribution of cholinergic binding sites in fetal human brain

G. Lunt, S. Wonnacott, R. Harrison, 1986, Neurochemical Research.

Voltage‐Sensitive Ca2+ Channels Involved in Nicotinic Receptor‐Mediated [3H]Dopamine Release from Rat Striatal Synaptosomes

S. Wonnacott, L. Soliakov, 1996, Journal of neurochemistry.

The paradox of nicotinic acetylcholine receptor upregulation by nicotine.

S Wonnacott, S. Wonnacott, 1990, Trends in pharmacological sciences.

Presynaptic nicotinic receptors and the modulation of transmitter release.

A. Drasdo, S. Wonnacott, P. Rowell, 1990, Ciba Foundation symposium.

Stereoselective Nicotine‐Induced Release of Dopamine from Striatal Synaptosomes: Concentration Dependence and Repetitive Stimulation

G. Lunt, S. Wonnacott, C. Rapier, 1988, Journal of neurochemistry.

Nicotinic Acetylcholine Receptors Control Encoding and Retrieval of Associative Recognition Memory through Plasticity in the Medial Prefrontal Cortex

Z. Bashir, E. Warburton, S. Wonnacott, 2018, Cell reports.

Nicotinic acetylcholine receptors and the regulation of neuronal signalling.

S. Wonnacott, F. Dajas-Bailador, 2004, Trends in pharmacological sciences.

α‐Bungarotoxin Binds to Low‐Affinity Nicotine Binding Sites in Rat Brain

S. Wonnacott, 1986 .

Megacystis-microcolon-intestinal hypoperistalsis syndrome and the absence of the α3 nicotinic acetylcholine receptor subunit

Geraint T. Williams, G. Thomas, B. Jasani, 2001 .

Characterization of Nicotinic Receptor‐Mediated [3H]Dopamine Release from Synaptosomes Prepared from Mouse Striatum

A. C. Collins, A. Collins, M. Marks, 1992, Journal of neurochemistry.

The Effects of Nicotine on the Regulation of Neuronal 7 Nicotinic Acetylcholine Receptors and Intracellular Signalling Pathways

S. Wonnacott, R. Tuominen, 2007 .

Intracellular Ca2+ signals evoked by stimulation of nicotinic acetylcholine receptors in SH‐SY5Y cells: contribution of voltage‐operated Ca2+ channels and Ca2+ stores

S. Wonnacott, F. Dajas-Bailador, A. Mogg, 2002, Journal of neurochemistry.

Characterisation of the binding of [3H]methyllycaconitine: a new radioligand for labelling α7-type neuronal nicotinic acetylcholine receptors

B. Potter, A. Wolstenholme, I. S. Blagbrough, 1999, Neuropharmacology.

Presynaptic nicotinic ACh receptors

S. Wonnacott, Susan Wonnacott, 1997, Trends in Neurosciences.

Antibodies to nicotinic acetylcholine receptors used to probe the structural and functional relationships between brain α-bungarotoxin binding sites and nicotinic receptors

S. Wonnacott, A. Mills, 1984, Neurochemistry International.

Alpha7 nicotinic acetylcholine receptor expression in Alzheimer's disease: receptor densities in brain regions of the APP(SWE) mouse model and in human peripheral blood lymphocytes.

Roy W Jones, I. Jones, K. Dineley, 2006, Journal of molecular neuroscience : MN.

Molecular and cellular mechanisms of action of nicotine in the CNS.

S. Wonnacott, J. Barik, 2009, Handbook of experimental pharmacology.

Neuronal nicotinic receptors

S. Wonnacott, Susan Wonnacott, Christopher G. V. Sharples, 2001 .

ABT-089 [2-methyl-3-(2-(S)-pyrrolidinylmethoxy)pyridine]: I. A potent and selective cholinergic channel modulator with neuroprotective properties.

D. Donnelly-roberts, D. Mckenna, S. Arneric, 1997, The Journal of pharmacology and experimental therapeutics.

The anticonvulsant MK-801 interacts with peripheral and central nicotinic acetylcholine receptor ion channels.

A. S. Ramoa, E. Albuquerque, S. Wonnacott, 1990, The Journal of pharmacology and experimental therapeutics.

Relationship between up-regulation of nicotine binding sites in rat brain and delayed cognitive enhancement observed after chronic or acute nicotinic receptor stimulation

J. Gray, M. Calaminici, F. Abdulla, 1996, Psychopharmacology.

Methyl lycaconitine: A novel nicotinic antagonist

D. Bertrand, A. Drasdo, S. Wonnacott, 1992, Molecular and Cellular Neuroscience.

Nicotinic acetylcholine receptors and the ascending dopamine pathways.

S. Wonnacott, P. D. Livingstone, 2009, Biochemical pharmacology.

The Effect of Acetylcholine Release on Choline Fluxes in Isolated Synaptic Terminals

S. Wonnacott, R. Marchbanks, M. A. Rubió, 1981, Journal of neurochemistry.

Inhibition by botulinum toxin of depolarization-evoked release of (14C)acetylcholine from synaptosomes in vitro.

S. Wonnacott, R. Marchbanks, 1976, The Biochemical journal.

alpha-bungarotoxin-sensitive nicotinic receptors indirectly modulate [(3)H]dopamine release in rat striatal slices via glutamate release.

S. Wonnacott, S. Kaiser, 2000, Molecular pharmacology.

Moxonidin als Initialtherapie und in Kombination bei der Behandlung der essentiellen Hypertonie: Ergebnisse der Topic-Studie (Trial of Physiotens in Combination)

S. Wonnacott, B. Jäger, Verboom Cn, 2000 .

Use of moxonidine as initial therapy and in combination in the treatment of essential hypertension - results of the TOPIC (Trial Of Physiotens In Combination) Study

S. Wonnacott, B. Jäger, Verboom Cn, 1999 .

Differential coupling of α7 and non‐α7 nicotinic acetylcholine receptors to calcium‐induced calcium release and voltage‐operated calcium channels in PC12 cells

J. Kew, S. Wonnacott, Katharine Hanrott, 2007, Journal of neurochemistry.

Effects of chronic drug treatments on increases in intracellular calcium mediated by nicotinic acetylcholine receptors in SH‐SY5Y cells

S. Wonnacott, J. Pakkanen, D. L. Ridley, 2002, British journal of pharmacology.

Pharmacological characterization of a nicotinic autoreceptor in rat hippocampal synaptosomes

J. Sullivan, S. Wonnacott, P. Hutson, 1996, Neurochemical Research.

Hippocampal nicotinic autoreceptors modulate acetylcholine release.

P. Whiting, S. Wonnacott, P. Hutson, 1993, Biochemical Society transactions.

Neuronal nicotinic receptors: functional correlates of ligand binding sites.

S. Wonnacott, 1991, Biochemical Society transactions.

Presynaptic modulation of transmitter release by nicotinic receptors.

G. Lunt, S. Wonnacott, G. Lunt, 1989, Progress in brain research.

Nicotinic Modulation of [3H]Dopamine Release from Striatal Synaptosomes: Pharmacological Characterisation

G. Lunt, S. Wonnacott, C. Rapier, 1990, Journal of neurochemistry.

Why doesn't nicotinic ACh receptor immunoreactivity knock out?

I. Jones, S. Wonnacott, 2005, Trends in Neurosciences.

From ligand design to therapeutic efficacy: the challenge for nicotinic receptor research.

S. Wonnacott, B. Cassels, I. Bermúdez, 2005, Drug discovery today.

Molecular Determinants for Competitive Inhibition of α4β2 Nicotinic Acetylcholine Receptors

P. Biggin, S. Wonnacott, P. Iturriaga-Vásquez, 2010, Molecular Pharmacology.

Inhibition of alpha7 nicotinic receptors in the ventral hippocampus selectively attenuates reinstatement of morphine‐conditioned place preference and associated changes in AMPA receptor binding

S. Wonnacott, V. L. Wright, Polymnia Georgiou, 2018, Addiction biology.

Properties of α-bungarotoxin binding sites in foetal human brain

G. Lunt, S. Wonnacott, R. Harrison, 1985, Neurochemistry International.

Nicotinic ACh Receptors

S. Wonnacott, J. Barik, 2007 .

Direct C-11 functionalisation of anatoxin-a. Application to the synthesis of new ligand-based structural probes

S. Wonnacott, T. Gallagher, L. Ducry, 1997 .

A conserved arginine with non‐conserved function is a key determinant of agonist selectivity in α7 nicotinic ACh receptors

R. Sessions, C. Bouzat, A. Mulholland, 2021, British journal of pharmacology.

αConotoxin Arenatus IB[V11L,V16D] Is a Potent and Selective Antagonist at Rat and Human Native α7 Nicotinic Acetylcholine Receptors

S. Wonnacott, J. McIntosh, A. Kimura, 2008, Journal of Pharmacology and Experimental Therapeutics.

Regioselective demethylation of aconitine

B. Potter, I. S. Blagbrough, S. Wonnacott, 1994 .

Characterisation of multiple α-bungarotoxin binding sites in the aphid Myzus persicae (Hemiptera: Aphididae)

S. Reynolds, S. Wonnacott, R. Lind, 1999 .

Characterization of a nicotinic acetylcholine receptor from the insect Manduca sexta

S. Reynolds, A. Wolstenholme, S. Wonnacott, 1998, The European journal of neuroscience.

Behavioural and ligand-binding studies in rats with 1-acetyl-4-methylpiperazine, a novel nicotinic agonist

I. Stolerman, S. Wonnacott, P. Thomas, 2005, Psychopharmacology.

Drug discrimination and neurochemical studies in α7 null mutant mice: tests for the role of nicotinic α7 receptors in dopamine release

I. Stolerman, S. Wonnacott, J. Barik, 2009, Psychopharmacology.

Nicotine psychopharmacology : molecular, cellular, and behavioural aspects

I. Stolerman, M. Russell, S. Wonnacott, 1990 .

The Bidirectional Relationship Between Sleep and Inflammation Links Traumatic Brain Injury and Alzheimer’s Disease

Robert J. Williams, S. Wonnacott, R. Rowe, 2020, Frontiers in Neuroscience.

Sazetidine-A Activates and Desensitizes Native α7 Nicotinic Acetylcholine Receptors

S. Wonnacott, Jack L. Brown, 2014, Neurochemical Research.

Nicotine increases intracellular calcium in rat hippocampal neurons via voltage-gated calcium channels

J. Westwick, S. Wonnacott, C. Murphy, 1995, Neuroscience Letters.

Attentional effects of nicotinic agonists in rats

B. Hahn, I. Stolerman, S. Wonnacott, 2003, Neuropharmacology.

Differential activation of PKCδ in the substantia nigra of rats following striatal or nigral 6‐hydroxydopamine lesions

M. O'Neill, S. Wonnacott, T. Murray, 2008, The European journal of neuroscience.

Regioselective anthranoylation of demethylated aconitine : novel analogues of aconitine, inuline and methyllycaconitine

B. Potter, I. S. Blagbrough, S. Wonnacott, 1994 .

Effect of smoking and transdermal nicotine on colonic nicotinic acetylcholine receptors in ulcerative colitis.

B. Jasani, G. Williams, J. Lindstrom, 2003, QJM : monthly journal of the Association of Physicians.

THE USE OF NEUROTOXINS IN NEUROBIOLOGY: STUDIES WITH BOTULINUM TOXIN AND α-BUNGAROTOXIN

S. Wonnacott, 1980 .

Glutamate–Dopamine Crosstalk in the Rat Prefrontal Cortex is Modulated by Alpha7 Nicotinic Receptors and Potentiated by PNU-120596

J. Kew, S. Wonnacott, P. D. Livingstone, 2009, Journal of Molecular Neuroscience.

Alpha-conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes.

R. Lewis, A. Nicke, S. Wonnacott, 2004, European journal of biochemistry.

Presynaptic nicotinic acetylcholine receptors in the brain

S. Wonnacott, L. Soliakov, P. Redfern, 1996 .

Contrasting effects of the α7 nicotinic receptor antagonist methyllycaconitine in different rat models of heroin reinstatement

S. Wonnacott, D. Heal, Sharon L. Smith, 2021, Journal of psychopharmacology.

Presynaptic α7- and β2-Containing Nicotinic Acetylcholine Receptors Modulate Excitatory Amino Acid Release from Rat Prefrontal Cortex Nerve Terminals via Distinct Cellular Mechanisms

J. Kew, S. Wonnacott, J. Dickinson, 2008, Molecular Pharmacology.

Structure-activity studies of bicyclic and tricyclic analogues of methyllycaconitine.

B. Potter, A. Wolstenholme, I. S. Blagbrough, 1997, Biochemical Society transactions.

Integration of inhibitory and excitatory effects of α7 nicotinic acetylcholine receptor activation in the prelimbic cortex regulates network activity and plasticity

S. Wonnacott, V. L. Wright, Matt Udakis, 2016, Neuropharmacology.

Nicotinic receptors modulate transmitter cross talk in the CNS

I. Jones, S. Wonnacott, J. Barik, 2007, Journal of Molecular Neuroscience.

Precise Localization of α7 Nicotinic Acetylcholine Receptors on Glutamatergic Axon Terminals in the Rat Ventral Tegmental Area

I. Jones, S. Wonnacott, Susan Wonnacott, 2004, The Journal of Neuroscience.

Chapter 13 – Acetylcholine

S. Wonnacott, S. Fisher, 2012 .

Chronic ethanol administration alters activity in ventral tegmental area neurons after cessation of withdrawal hyperexcitability

S. Wonnacott, H. Little, W. P. Watson, 1998, Brain Research.

Nudicauline and elatine as potent norditerpenoid ligands at rat neuronal alpha-bungarotoxin binding sites: importance of the 2-(methylsuccinimido)benzoyl moiety for neuronal nicotinic acetylcholine receptor binding.

B. Potter, I. S. Blagbrough, S. Wonnacott, 1996, Journal of medicinal chemistry.

α7 and non‐α7 nicotinic acetylcholine receptors modulate dopamine release in vitro and in vivo in the rat prefrontal cortex

J. Kew, C. Gotti, S. Wonnacott, 2009, The European journal of neuroscience.

Indirect Modulation by α7 Nicotinic Acetylcholine Receptors of Noradrenaline Release in Rat Hippocampal Slices: Interaction with Glutamate and GABA Systems and Effect of Nicotine Withdrawal

S. Wonnacott, J. Barik, 2006, Molecular Pharmacology.

Precise localization of alpha7 nicotinic acetylcholine receptors on glutamatergic axon terminals in the rat ventral tegmental area.

I. Jones, S. Wonnacott, 2004, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Inhibit Dopamine Release Axons: One Source of a Retrograde Signal That Can Striatal Medium Spiny Neurons But Not Dopamine Generation in

M. Rice, M. Quik, S. Wonnacott, 2015 .

Nicotine: from molecular mechanisms to behaviour.

D. Balfour, S. Wonnacott, Nimish Sidhpura, 2005, Current opinion in pharmacology.

A general mechanism for signal propagation in the nicotinic acetylcholine receptor family.

Christopher J. Woods, G. Ciccotti, R. Sessions, 2019, Journal of the American Chemical Society.

Comparison of the effects of bupropion on nicotinic receptor-evoked [(3)H]dopamine release from rat striatal synaptosomes and slices.

S. Wonnacott, P. Redfern, Nimish Sidhpura, 2007, European journal of pharmacology.

Development of an anti-cotinine vaccine to potentiate nicotine-based smoking cessation strategies.

S. Wonnacott, P. Barnett, T. Gallagher, 2007, Vaccine.

Inhibition by Botulinum Toxin of Acetylcholine Release from Synaptosomes: Latency of Action and the Role of Gangliosides

S. Wonnacott, 1980, Journal of neurochemistry.

Relationship of choline uptake to acetylcholine synthesis and release.

S. Wonnacott, R. Marchbanks, 1979, Progress in brain research.

Ca2+ UPTAKE BY SYNAPTOSOMES AND ITS EFFECT ON THE INHIBITION OF ACETYLCHOLINE RELEASE BY BOTULINUM TOXIN

S. Wonnacott, C. Fiol, R. Marchbanks, 1978, Journal of neurochemistry.

A radioenzymic assay for acetylcholine and the problems encountered during its development and application.

S. Wonnacott, R. Marchbanks, 1975, Biochemical Society transactions.

Nicotinic Acetylcholine Receptors in Insect Ganglia and Mammalian Brain: Some Comparisons

G. Lunt, S. Wonnacott, D. Macallan, 1988 .

Nicotinic acetylcholine receptors in cultured neurons from the hippocampus and brain stem of the rat characterized by single channel recording

E. Albuquerque, S. Wonnacott, H. Rapoport, 1987, FEBS letters.

Sensitivity of rat frontal cortical neurones to nicotine is increased by chronic administration of nicotine and by lesions of the nucleus basalis magnocellularis: Comparison with numbers of [3H]nicotine binding sites

J. Gray, M. Calaminici, F. Abdulla, 1995, Synapse.

Double‐blind comparative multicentre study of fluvoxamine and mianserin in the treatment of major depressive episode in elderly people

S. Wonnacott, A. Phanjoo, A. Hodgson, 1991, Acta psychiatrica Scandinavica.

Associated proteins: The universal toolbox controlling ligand gated ion channel function.

D. Bertrand, S. Wonnacott, T. Araud, 2010, Biochemical pharmacology.

α7 nicotinic acetylcholine receptor expression in Alzheimer's disease

I. Jones, K. Dineley, M. O'Neill, 2007, Journal of Molecular Neuroscience.

Presynaptic Nicotinic Modulation of Dopamine Release in the Three Ascending Pathways Studied by In Vivo Microdialysis: Comparison of Naive and Chronic Nicotine‐Treated Rats

S. Wonnacott, P. Redfern, D. Marshall, 1997, Journal of neurochemistry.

Localization of neuronal nicotinic acetylcholine receptor subunits in rat substantia nigra and dorsal striatum

J. Bolam, I. Jones, S. Wonnacott, 2002 .

Neurotoxins: nature's untapped bounty.

S. Wonnacott, F. Dajas, 1994, Trends in pharmacological sciences.

Report of Scottish General Practitioner Open Multicentre Study of Isoxsuprine (Duvadilan Retard) in the Management of Intermittent Claudication

W. Mackenzie, S. Wonnacott, 1985, The British journal of clinical practice.

The Lesion of the Rat Substantia Nigra pars compacta Dopaminergic Neurons as a Model for Parkinson's Disease Memory Disabilities

N. Canteras, S. Wonnacott, C. Da Cunha, 2002, Cellular and Molecular Neurobiology.

Trimethoprim and co-trimoxazole: a comparison of their use in respiratory tract infections.

S. Amyes, S. Wonnacott, C. Doherty, 1986, Scandinavian journal of infectious diseases.

Presynaptic nicotinic receptors modulating dopamine release in the rat striatum.

I. Jones, S. Wonnacott, A. Mogg, 2000, European journal of pharmacology.

Presynaptic neuronal nicotinic receptors : Pharmacology, heterogeneity, and cellular mechanisms

S. Wonnacott, L. Soliakov, S. Kaiser, 2000 .

Interrelationship of concanavalin-A-binding and antigenic sites on the acetylcholine receptor from Torpedo marmorata.

S. Wonnacott, R. Harrison, T. Barkas, 1980, European journal of biochemistry.

Oligomerisation differentially affects the acute and chronic actions of amyloid-β in vitro

N. Evans, S. Wonnacott, Neal Innocent, 2010, Neuropharmacology.

A Double-Blind Comparison of Moxonidine and Atenolol in the Management of Patients with Mild-to-Moderate Hypertension

S. Wonnacott, B. Prichard, D. Laws, 1992 .

Nicotine induces tyrosine hydroxylase plasticity in the neurodegenerating striatum

S. Wonnacott, F. Dajas, J. Urbanavicius, 2007, Journal of neurochemistry.

alpha-Bungarotoxin binding sites in rat hippocampal and cortical cultures: initial characterisation, colocalisation with alpha 7 subunits and up-regulation by chronic nicotine treatment.

J. Lindstrom, S. Wonnacott, G. Barrantes, 1995, Brain Research.

Xenopus laevis RIC-3 enhances the functional expression of the C. elegans homomeric nicotinic receptor, ACR-16, in Xenopus oocytes

Andrew K. Jones, D. Sattelle, A. Wolstenholme, 2012, Journal of neurochemistry.

Neurochemistry of Drug Dependence

S. Wonnacott, G. Lunt, 1994 .

The role of synthetic chemistry in the production of standards for toxin analysis

S. Wonnacott, P. Brough, T. Jefferies, 1994 .

In vivo modulation of dopaminergic nigrostriatal pathways by cytisine derivatives: implications for Parkinson's Disease.

S. Wonnacott, B. Cassels, Marco Rebolledo-Fuentes, 2008, European journal of pharmacology.

In silico characterization of cytisinoids docked into an acetylcholine binding protein.

S. Wonnacott, B. Cassels, Margot Paulino Zunini, 2010, Bioorganic & medicinal chemistry letters.

Interaction of p-aminophenyldichloroarsine, an arsenical with specificity for vicinal cysteines, with [3H]cytisine binding sites in rat brain membranes.

S. Wonnacott, A. Aplin, 1994, Biochemical pharmacology.

Oligomerisation differentially affects the acute and chronic actions of amyloid-β in vitro

N. Evans, S. Wonnacott, Neal Innocent, 2010, Neuropharmacology.

Nicotinic involvement in ACh-DA interaction?

S. Wonnacott, 1989, TIPS - Trends in Pharmacological Sciences.

ABT — 418, a Novel Nicotinic Agonist

A. D. Rodrigues, W. J. Jackson, Y. Martin, 1994 .

Nicotine-induced upregulation of αBungarotoxin (α Bgt) binding sites in cultured rat hippocampal neurons

S. Wonnacott, A. Rogers, 1995 .

Inhibition of alpha7 nicotinic receptors in the ventral hippocampus selectively attenuates reinstatement of morphine‐conditioned place preference and associated changes in AMPA receptor binding

S. Wonnacott, V. L. Wright, Polymnia Georgiou, 2018, Addiction biology.

Gates and filters: unveiling the physiological roles of nicotinic acetylcholine receptors in dopaminergic transmission

S. Wonnacott, 2008, British journal of pharmacology.

Presynaptic nicotinic acetylcholine receptors: subtypes mediating neurotransmitter release

I. Jones, S. Wonnacott, Bradly Alicea, 2001 .

Parallel increases in [α-125I]bungarotoxin binding and α7 nicotinic subunit immunoreactivity during the development of rat hippocampal neurons in culture

J. Lindstrom, S. Wonnacott, A. Futerman, 1997, Neuroscience Letters.

Presynaptic Nicotinic Receptors in the CNS

S. Wonnacott, L. Soliakov, Susan Wonnacott, 1997 .

Comparison of the effects of neosurugatoxin and α-bungarotoxin on nicotinic acetylcholine receptors in rat brain

G. Lunt, S. Wonnacott, R. Harrison, 1985 .

In silico characterization of cytisinoids docked into an acetylcholine binding protein.

S. Wonnacott, B. Cassels, F. Dajas, 2010, Bioorganic & Medicinal Chemistry Letters.

Why doesn't nicotinic ACh receptor immunoreactivity knock out?

I. Jones, S. Wonnacott, 2005, Trends in Neurosciences.

Presynaptic (cid:1) 7- and (cid:2) 2-Containing Nicotinic Acetylcholine Receptors Modulate Excitatory Amino Acid Release from Rat Prefrontal Cortex Nerve Terminals via Distinct Cellular Mechanisms

J. Kew, S. Wonnacott, J. Dickinson, 2008 .