K. Nishioka

发表

Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein.

D. Reinberg, H. Erdjument-Bromage, P. Tempst, 2002, Genes & development.

Expression and differential intracellular localization of two major forms of human 8-oxoguanine DNA glycosylase encoded by alternatively spliced OGG1 mRNAs.

Y. Nakabeppu, T. Ohtsubo, D. Kang, 1999, Molecular biology of the cell.

Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation.

D. Reinberg, C. Allis, H. Erdjument-Bromage, 2002, Genes & development.

Impairment of mitochondrial DNA repair enzymes against accumulation of 8-oxo-guanine in the spinal motor neurons of amyotrophic lateral sclerosis

Satoshi O. Suzuki, T. Iwaki, Y. Nakabeppu, 2002, Acta Neuropathologica.

Growing oocyte-specific transcription-dependent de novo DNA methylation at the imprinted Zrsr1-DMR

H. Soejima, H. Koseki, K. Nishioka, 2018, Epigenetics & chromatin.

Growing oocyte-specific transcription-dependent de novo DNA methylation at the imprinted Zrsr1-DMR

H. Soejima, H. Koseki, K. Nishioka, 2018, Epigenetics & Chromatin.

PMEPA1 and NEDD4 control the proton production of osteoclasts by regulating vesicular trafficking

Y. Urano, M. Mawatari, K. Nishioka, 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Comprehensive and quantitative multilocus methylation analysis reveals the susceptibility of specific imprinted differentially methylated regions to aberrant methylation in Beckwith–Wiedemann syndrome with epimutations

T. Mukai, T. Ogata, R. Kosaki, 2014, Genetics in Medicine.

PR-Set 7 Is a Nucleosome-Specific Methyltransferase that Modifies Lysine 20 of Histone H 4 and Is Associated with Silent

D. Reinberg, C. Allis, R. Steward, 2002 .

Expression of 8-oxoguanine DNA glycosylase (OGG1) in Parkinson’s disease and related neurodegenerative disorders

N. Hattori, Y. Nakabeppu, K. Nishioka, 2005, Acta Neuropathologica.

Selective increase in cellular Aβ42 is related to apoptosis but not necrosis

A. Tomlinson, S. Younkin, J. Kira, 2000 .

Selective increase in cellular A beta 42 is related to apoptosis but not necrosis.

A. Tomlinson, Stephen Naylor, S. Younkin, 2000, Neuroreport.

A novel de novo point mutation of the OCT‐binding site in the IGF2/H19‐imprinting control region in a Beckwith–Wiedemann syndrome patient

T. Ogata, H. Soejima, H. Koseki, 2014, Clinical genetics.

Multi-forms of human MTH1 polypeptides produced by alternative translation initiation and single nucleotide polymorphism.

Y. Nakabeppu, M. Sekiguchi, K. Nishioka, 1999, Nucleic acids research.

Tips in analyzing antibodies directed against specific histone tail modifications.

D. Reinberg, K. Nishioka, K. Sarma, 2004, Methods in enzymology.

Prostate transmembrane protein androgen induced 1 is induced by activation of osteoclasts and regulates bone resorption

K. Nishioka, A. Kukita, T. Kukita, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Methods and tips for the purification of human histone methyltransferases.

D. Reinberg, K. Nishioka, 2003, Methods.

PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin.

Paul Tempst, Danny Reinberg, Hediye Erdjument-Bromage, 2002, Molecular cell.

Facile synthesis of site-specifically acetylated and methylated histone proteins: Reagents for evaluation of the histone code hypothesis

Danny Reinberg, Neil Kelleher, David Bauman, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Human APE2 protein is mostly localized in the nuclei and to some extent in the mitochondria, while nuclear APE2 is partly associated with proliferating cell nuclear antigen.

K. Sakumi, Y. Nakabeppu, Y. Sakai, 2001, Nucleic acids research.

Histone lysine methylation: a signature for chromatin function.

Danny Reinberg, Kenichi Nishioka, D. Reinberg, 2003, Trends in genetics : TIG.

Ash1l Methylates Lys36 of Histone H3 Independently of Transcriptional Elongation to Counteract Polycomb Silencing

H. Handa, H. Soejima, H. Koseki, 2013, PLoS genetics.

Epigenetic regulations of chromatin dynamics: A role of noncoding RNAs in epigenetic activation of Drosophila Hox genes

K. Nishioka, S. Hirose, 2007 .

Drosophila GAGA factor directs histone H3.3 replacement that prevents the heterochromatin spreading.

T. Shimojima, K. Nishioka, S. Hirose, 2007, Genes & development.

The Trithorax protein Ash1L promotes myoblast fusion by activating Cdon expression

K. Nishioka, J. Garcia-Manteiga, Ivan Molineris, 2018, Nature Communications.

Identification of consensus motifs associated with mitotic recombination and clinical characteristics in patients with paternal uniparental isodisomy of chromosome 11.

T. Mukai, H. Soejima, K. Nishioka, 2016, Human molecular genetics.

Autosomal recessive cystinuria caused by genome‐wide paternal uniparental isodisomy in a patient with Beckwith–Wiedemann syndrome

T. Mukai, K. Yoshiura, H. Soejima, 2015, Clinical genetics.

Comprehensive analyses of imprinted differentially methylated regions reveal epigenetic and genetic characteristics in hepatoblastoma

Y. Oda, H. Soejima, T. Taguchi, 2013, BMC Cancer.

Homozygous deletion of DIS3L2 exon 9 due to non-allelic homologous recombination between LINE-1s in a Japanese patient with Perlman syndrome

K. Yoshiura, H. Soejima, K. Nishioka, 2013, European Journal of Human Genetics.

Mitotic-specific methylation of histone H4 Lys 20 follows increased PR-Set7 expression and its localization to mitotic chromosomes.

D. Reinberg, C. Allis, R. Steward, 2002, Genes & development.

The Trithorax protein Ash1L promotes myoblast fusion by activating Cdon expression

K. Nishioka, J. Garcia-Manteiga, Ivan Molineris, 2018, Nature Communications.

Switching Partners in a Regulatory Tango

D. Reinberg, K. Nishioka, 2001, Science.

Unbiased shRNA screening, using a combination of FACS and high-throughput sequencing, enables identification of novel modifiers of Polycomb silencing

H. Soejima, K. Nishioka, Hitomi Miyazaki, 2018, Scientific Reports.

Degradation of the Tumor Suppressor PDCD4 Is Impaired by the Suppression of p62/SQSTM1 and Autophagy

Hirokazu Takahashi, Jing Guo, K. Nishioka, 2020, Cells.

Identification of human MutY homolog (hMYH) as a repair enzyme for 2-hydroxyadenine in DNA and detection of multiple forms of hMYH located in nuclei and mitochondria

Y. Nakabeppu, K. Nishioka, S. Iwai, 2000, Nucleic acids research.

Transcription. Switching partners in a regulatory tango.

D. Reinberg, K. Nishioka, 2001, Science.

A novel role of helix‐loop‐helix transcriptional factor Bhlhe40 in osteoclast activation

Y. Urano, M. Mawatari, H. Soejima, 2022, Journal of cellular physiology.

The HUS1B promoter is hypomethylated in the placentas of low-birth-weight infants.

S. Toda, S. Takeda, H. Soejima, 2016, Gene.

Expression of 8-oxoguanine DNA glycosylase is reduced and associated with neurofibrillary tangles in Alzheimer's disease brain

T. Iwaki, Y. Nakabeppu, K. Nishioka, 2002, Acta Neuropathologica.

Unbiased shRNA screening, using a combination of FACS and high-throughput sequencing, enables identification of novel modifiers of Polycomb silencing

H. Soejima, K. Nishioka, Hitomi Miyazaki, 2018, Scientific Reports.

Discovery of first-in-class inhibitors of ASH1L histone methyltransferase with anti-leukemic activity

Y. Dou, T. Cierpicki, J. Grembecka, 2021, Nature Communications.

Mbf1 ensures Polycomb silencing by protecting E(z) mRNA from degradation by Pacman

H. Soejima, K. Nishioka, Xian-Feng Wang, 2018, Development.