D. Knoell

发表

The human zinc transporter SLC39A8 (Zip8) is critical in zinc-mediated cytoprotection in lung epithelia.

W. Sadee, A. Papp, B. Besecker, 2008, American journal of physiology. Lung cellular and molecular physiology.

Zinc modulates the innate immune response in vivo to polymicrobial sepsis through regulation of NF-kappaB.

Ju-Ping Lai, D. Guttridge, B. Besecker, 2010, American Journal of Physiology - Lung cellular and Molecular Physiology.

D. Knoell, 1998, The Annals of pharmacotherapy.

Impact of zinc metabolism on innate immune function in the setting of sepsis.

D. Knoell, Mingjie Liu, 2010, International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition.

Modeling of an immune response: Queuing network analysis of the impact of zinc and cadmium on macrophage activation

T. Wysocki, D. Knoell, B. Wysocki, 2020, Biotechnology and bioengineering.

Gene expression following direct injection of DNA into liver.

D. M. Carlson, F. Szoka, R. Malone, 1994, Human gene therapy.

Inhibition of the phosphatase PTEN protects mice against oleic acid‐induced acute lung injury

Ju-Ping Lai, S. Bao, D. Knoell, 2009, British journal of pharmacology.

Clinical implications of gene therapy for alpha 1-antitrypsin deficiency.

D. Knoell, M. Wewers, 1995, Chest.

Gene targeting of CFTR DNA in CF epithelial cells.

K. Kunzelmann, D. Knoell, J. Legendre, 1996, Gene therapy.

Zinc Modulates Endotoxin-Induced Human Macrophage Inflammation through ZIP8 Induction and C/EBPβ Inhibition

S. Bao, D. Knoell, Claire E. Dodd, 2017, PloS one.

Extracellular regulation of interleukin (IL)-1beta through lung epithelial cells and defective IL-1 type II receptor expression.

D. Knoell, M. Wewers, K. R. Coulter, 1999, American journal of respiratory cell and molecular biology.

Phosphatase and tensin homologue deleted on chromosome ten (PTEN) as a molecular target in lung epithelial wound repair

Ju-Ping Lai, J. Dalton, D. Knoell, 2007, British journal of pharmacology.

Sepsis: links between pathogen sensing and organ damage.

M. Exline, E. Crouser, D. Knoell, 2008, Current pharmaceutical design.

A genotyping exercise for pharmacogenetics in pharmacy practice.

Jeffrey S. Johnston, S. Bao, D. Knoell, 2009, American journal of pharmaceutical education.

Cadmium-mediated toxicity of lung epithelia is enhanced through NF-κB-mediated transcriptional activation of the human zinc transporter ZIP8.

S. Bao, D. Knoell, Mingjie Liu, 2012, American journal of physiology. Lung cellular and molecular physiology.

RETRACTED: TGF-β1 regulation of human AT1 receptor mRNA splice variants harboring exon 2

T. Elton, D. Knoell, Mickey M. Martin, 2006, Molecular and Cellular Endocrinology.

Zinc Signal in Inflammation

Ming Liu, D. Knoell, 2014 .

ZIP8 regulates host defense through zinc-mediated inhibition of NF-κB.

D. Nebert, D. Killilea, S. Bao, 2013, Cell reports.

Pharmacogenomics: A Scientific Revolution in Pharmaceutical Sciences and Pharmacy Practice. Report of the 2001-2002 Academic Affairs Committee

S. Meyer, D. Knoell, R. Straubinger, 2001 .

IκBζ Regulates Human Monocyte Pro-Inflammatory Responses Induced by Streptococcus pneumoniae

D. Knoell, M. Wewers, S. King, 2016, PloS one.

Zinc deficiency augments leptin production and exacerbates macrophage infiltration into adipose tissue in mice fed a high-fat diet.

M. Failla, M. Belury, D. Killilea, 2013, The Journal of nutrition.

Divalent Metal Uptake and the Role of ZIP8 in Host Defense Against Pathogens

S. Haq, D. Knoell, D. Samuelson, 2022, Frontiers in Cell and Developmental Biology.

Integrative assessment of chlorine-induced acute lung injury in mice.

D. Prows, M. You, J. McDunn, 2012, American journal of respiratory cell and molecular biology.

Functional characterization of the peptide transporter PEPT2 in primary cultures of human upper airway epithelium.

Praveen M. Bahadduri, P. Swaan, W. Sadee, 2005, American journal of respiratory cell and molecular biology.

Churg-Strauss syndrome associated with zafirlukast.

D. Knoell, J. N. Allen, J. Lucas, 1998, Chest.

Alpha 1-antitrypsin and protease complexation is induced by lipopolysaccharide, interleukin-1beta, and tumor necrosis factor-alpha in monocytes.

D. Knoell, M. Wewers, K. R. Coulter, 1998, American journal of respiratory and critical care medicine.

Formyl peptide receptor ligands promote wound closure in lung epithelial cells.

Ju-Ping Lai, E. Crouser, S. Bao, 2011, American journal of respiratory cell and molecular biology.

Zinc Signals in Inflammation

D. Knoell, Sannette C. Hall, 2019, Zinc Signaling.

Essential Role of Zinc and Zinc Transporters in Myeloid Cell Function and Host Defense against Infection

D. Knoell, M. Sapkota, 2018, Journal of immunology research.

Lymphocytes Produce IL-1β in Response to Fcγ Receptor Cross-Linking: Effects on Parenchymal Cell IL-8 Release

B. Rovin, C. Marsh, D. Knoell, 1998, The Journal of Immunology.

Accumulation of metals in GOLD4 COPD lungs is associated with decreased CFTR levels

G. Nuovo, D. Killilea, P. Diaz, 2014, Respiratory Research.

TGF-beta1 stimulates human AT1 receptor expression in lung fibroblasts by cross talk between the Smad, p38 MAPK, JNK, and PI3K signaling pathways.

Jinmai Jiang, T. Elton, D. Feldman, 2007, American journal of physiology. Lung cellular and molecular physiology.

Bacterial peptide recognition and immune activation facilitated by human peptide transporter PEPT2.

Praveen M. Bahadduri, S. Ekins, P. Swaan, 2008, American journal of respiratory cell and molecular biology.

Induction of Interleukin‐8 Release by Lung Epithelium with Cystic Fibrosis Epithelial Lining Fluid Is Marginally Affected by Inhibitors of Interleukin‐1β

R. Castile, D. Knoell, M. Wewers, 2000, Pharmacotherapy.

Intestinal epithelium is more susceptible to cytopathic injury and altered permeability than the lung epithelium in the context of acute sepsis

E. Crouser, S. Bao, D. Knoell, 2011, International journal of experimental pathology.

Cadmium regulates the expression of the CFTR chloride channel in human airway epithelial cells.

N. Parinandi, D. Knoell, K. Maloney, 2010, Toxicological sciences : an official journal of the Society of Toxicology.

Cadmium attenuates the macrophage response to LPS through inhibition of the NF-κB pathway.

S. Bao, D. Knoell, Mingjie Liu, 2016, American journal of physiology. Lung cellular and molecular physiology.

Alveolar Epithelial Cells in Mycobacterium tuberculosis Infection: Active Players or Innocent Bystanders?

D. Knoell, J. Torrelles, J. Scordo, 2015, Journal of Innate Immunity.

Pulmonary siRNA delivery for lung disease: Review of recent progress and challenges.

D. Knoell, D. Oupický, T. Wyatt, 2020, Journal of controlled release : official journal of the Controlled Release Society.

Opposing effect by cytokines on Fas-mediated apoptosis in A549 lung epithelial cells.

A. Doseff, Yijie Wang, C. Marsh, 2002, American journal of respiratory cell and molecular biology.

Critical Role of Zinc Transporter (ZIP8) in Myeloid Innate Immune Cell Function and the Host Response against Bacterial Pneumonia

K. Bailey, D. Knoell, D. Samuelson, 2021, The Journal of Immunology.

Mitochondrial Transcription Factor A Serves as a Danger Signal by Augmenting Plasmacytoid Dendritic Cell Responses to DNA

E. Crouser, S. Bao, D. Knoell, 2012, The Journal of Immunology.

Zinc modulates cytokine-induced lung epithelial cell barrier permeability.

D. Knoell, S. Bao, 2006, American journal of physiology. Lung cellular and molecular physiology.

Human gene therapy for hereditary diseases: a review of trials.

D. Knoell, I. M. Yiu, 1998, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

INABILITY TO SECRETE IL-1 Infection : Burkholderia cenocepacia Cell Proinflammatory Response to Analysis of Human Bronchial Epithelial

B. Besecker, D. Knoell, Jonathan P Butchar, 2013 .

Analysis of Human Bronchial Epithelial Cell Proinflammatory Response to Burkholderia cenocepacia Infection

B. Besecker, D. Knoell, Jonathan P Butchar, 2012, The Journal of Biological Chemistry.

Vocal Cord Dysfunction Presenting as “Steroid-Dependent” Asthma

C. Marsh, D. Knoell, 1997 .

Perfluorocarbon Nanoemulsions Enhance Therapeutic siRNA Delivery in the Treatment of Pulmonary Fibrosis

K. Bailey, D. Knoell, D. Oupický, 2022, Advanced science.

Tissue-Specific Induction of Mouse ZIP8 and ZIP14 Divalent Cation/Bicarbonate Symporters by, and Cytokine Response to, Inflammatory Signals

D. Nebert, D. Knoell, Marina Gálvez-Peralta, 2014, International journal of toxicology.

Elemental Ingredients in the Macrophage Cocktail: Role of ZIP8 in Host Response to Mycobacterium tuberculosis

W. Sadee, A. Azad, A. Papp, 2017, International journal of molecular sciences.

ZIP8-Mediated Intestinal Dysbiosis Impairs Pulmonary Host Defense against Bacterial Pneumonia

D. Knoell, D. Samuelson, D. Murry, 2022, International journal of molecular sciences.

Allelic mRNA expression imbalance in C-type lectins reveals a frequent regulatory SNP in the human surfactant protein A (SP-A) gene

W. Sadee, A. Azad, A. Papp, 2012, Genes and Immunity.

The adverse impact of cadmium on immune function and lung host defense.

D. Knoell, T. Wyatt, 2020, Seminars in cell & developmental biology.

Functional genomic assessment of phosgene-induced acute lung injury in mice.

Emrah Kostem, E. Eskin, D. Prows, 2013, American journal of respiratory cell and molecular biology.

Correlation of HIV-1 Detection and Histology in AIDS-Associated Emphysema

G. Nuovo, P. Diaz, D. Knoell, 2005, Diagnostic molecular pathology : the American journal of surgical pathology, part B.

Zinc Regulates the Acute Phase Response and Serum Amyloid A Production in Response to Sepsis through JAK-STAT3 Signaling

Lianbo Yu, D. Knoell, Mingjie Liu, 2014, PloS one.

Pharm.D. Pathways to Biomedical Research: The National Institutes of Health Special Conference on Pharmacy Research

P. Kroboth, H. McLeod, W. Figg, 2008, Pharmacotherapy.

Endothelial dysfunction and claudin 5 regulation during acrolein-induced lung injury.

D. Knoell, Hannah Pope-Varsalona, Y. Di, 2011, American journal of respiratory cell and molecular biology.

Sequential Processing of Human ProIL-1β by Caspase-1 and Subsequent Folding Determined by a Combined In Vitro and In Silico Approach

P. Swaan, D. Knoell, M. Wewers, 2001, Pharmaceutical Research.

Zinc deficiency increases organ damage and mortality in a murine model of polymicrobial sepsis*

E. Crouser, B. Besecker, D. Knoell, 2009, Critical care medicine.

Zinc modulates airway epithelium susceptibility to death receptor-mediated apoptosis.

D. Knoell, S. Bao, 2006, American journal of physiology. Lung cellular and molecular physiology.

Anticholinergic medications for the treatment of chronic obstructive pulmonary disease

D. Knoell, 2007 .

PTEN inhibition improves wound healing in lung epithelia through changes in cellular mechanics that enhance migration.

S. Ghadiali, Ju-Ping Lai, D. Knoell, 2012, American journal of physiology. Lung cellular and molecular physiology.

Zinc in critical illness and sepsis.

L. Rink, B. Besecker, D. Knoell, 2011 .

Imbalance in zinc homeostasis enhances lung Tissue Loss following cigarette smoke exposure.

J. Zweier, D. Knoell, M. Borchers, 2020, Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements.

Keratinocyte growth factor induces Akt kinase activity and inhibits Fas-mediated apoptosis in A549 lung epithelial cells.

A. Doseff, Yijie Wang, C. Marsh, 2005, American journal of physiology. Lung cellular and molecular physiology.

Keratinocyte growth factor induces Akt kinase activity and inhibits Fas-mediated apoptosis in A 549 lung epithelial cells

A. Doseff, Yijie Wang, C. Marsh, 2004 .

Measurement of Outcomes in Adults Receiving Pharmaceutical Care in a Comprehensive Asthma Outpatient Clinic

D. Knoell, D. Pathak, James N. Allen, 1998, Pharmacotherapy.

The Inherited Intestinal Microbiota from Myeloid-Specific ZIP8KO Mice Impairs Pulmonary Host Defense against Pneumococcal Pneumonia

Niaz Chowdhury, S. Haq, D. Knoell, 2023, Pathogens.

A comparison of zinc metabolism, inflammation, and disease severity in critically ill infected and noninfected adults early after intensive care unit admission.

M. Exline, G. Phillips, B. Besecker, 2011, The American journal of clinical nutrition.

enhance migration epithelia through changes in cellular mechanics that PTEN inhibition improves wound healing in lung

S. Ghadiali, Ju-Ping Lai, D. Knoell, 2014 .

The Clinical Pharmacist as Principal Investigator: A Commentary from the American College of Clinical Pharmacy

M. Munger, D. Knoell, J. Korth-Bradley, 2000, Pharmacotherapy.

Insufficient zinc intake enhances lung inflammation in response to agricultural organic dust exposure.

Lynette M. Smith, D. Romberger, D. Knoell, 2019, The Journal of nutritional biochemistry.

Mitochondrial Transcription Factor A Serves as a Danger Signal by Augmenting Plasmacytoid Dendritic Cell Responses to DNA

E. Crouser, D. Knoell, T. Papenfuss, 2012, The Journal of Immunology.

ZIP8 regulates host defense through zinc-mediated inhibition of NF-κB.

D. Nebert, D. Killilea, D. Knoell, 2013, Cell reports.

Intestinal epithelium is more susceptible to cytopathic injury and altered permeability than the lung epithelium in the context of acute sepsis

E. Crouser, D. Knoell, R. Fahy, 2011, International journal of experimental pathology.

Plasmacytoid Dendritic Cell Responses to as a Danger Signal by Augmenting Mitochondrial Transcription Factor A Serves

E. Crouser, S. Bao, D. Knoell, 2012 .

Regulation of Natural Killer Cell TGF-β and AhR Signaling Pathways Via the Intestinal Microbiota is Critical for Host Defense Against Alcohol-Associated Bacterial Pneumonia

D. Knoell, Deandra Smith, Mason Mandolfo, 2023, Research square.