Sabine Hadida

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Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770

Jinglan Zhou, P. Negulescu, P. Grootenhuis, 2009, Proceedings of the National Academy of Sciences.

Synthesis of tris(2-perfluorohexylethyl)tin hydride: A highly fluorinated tin hydride with advantageous features of easy purification

Sabine Hadida, D. Curran, Sun-Young Kim, 2003 .

tris(2-perfluorohexylethyl)tin azide: A new reagent for preparation of 5-substituted tetrazoles from nitriles with purification by fluorous/organic liquid-liquid extraction

Sabine Hadida, D. Curran, Sun-Young Kim, 1999 .

Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770

P. Negulescu, P. Grootenhuis, F. van Goor, 2009, Proceedings of the National Academy of Sciences.

Identification of potent CNS-penetrant thiazolidinones as novel CGRP receptor antagonists.

Sabine Hadida, C. Decker, A. Termin, 2014, Bioorganic & medicinal chemistry letters.

Tris(2-(perfluorohexyl)ethyl)tin Hydride: A New Fluorous Reagent for Use in Traditional Organic Synthesis and Liquid Phase Combinatorial Synthesis

Sabine Hadida, D. Curran, 1996 .

Hydroxymethylation of organic halides. Evaluation of a catalytic system involving a fluorous tin hydride reagent for radical carbonylation

I. Ryu, Sabine Hadida, D. Curran, 1997 .

Thermal Allylations of Aldehydes with a Fluorous Allylstannane. Separation of Organic and Fluorous Products by Solid Phase Extraction with Fluorous Reverse Phase Silica Gel

Sabine Hadida, D. Curran, Mu He, 1997 .

Rapid Fluorous Stille Coupling Reactions Conducted under Microwave Irradiation

A. Hallberg, Sabine Hadida, D. Curran, 1997 .

Preparation and reactions of 1-(tert-butyldimethylsilyl)-3-lithioindole. Regioselective synthesis of 3-substituted indoles

Sabine Hadida, S. Sathyanarayana, J. Bosch, 1994 .

Fluorous tin hydrides: A new family of reagents for use and reuse in radical reactions

Sabine Hadida, D. Curran, Sun-Young Kim, 1999 .

Palladium(0)-Catalyzed Heteroarylation of 2- and 3-Indolylzinc Derivatives. An Efficient General Method for the Preparation of (2-Pyridyl)indoles and Their Application to Indole Alkaloid Synthesis.

Sabine Hadida, J. Bosch, M. Amat, 1997, The Journal of organic chemistry.

Fluorous Synthesis: A Fluorous-Phase Strategy for Improving Separation Efficiency in Organic Synthesis

P. Wipf, A. Studer, Sabine Hadida, 1997, Science.

Radical Reactions with Alkyl and Fluoroalkyl (Fluorous) Tin Hydride Reagents in Supercritical CO2

E. Beckman, Sabine Hadida, M. Super, 1997 .

Studies on the Configurational Stability of 3-(2-Piperidyl)indoles.

Sabine Hadida, S. Sathyanarayana, J. Bosch, 1996, The Journal of organic chemistry.

Palladium-catalyzed heteroarylation of 1-(tert-butyldimethylsilyl)-3-indolylzinc chloride. Efficient synthesis of 3-(2-pyridyl)indoles

Sabine Hadida, J. Bosch, M. Amat, 1994 .

Addition of α-Lithiated Nitriles to Azaheterocycles

Sabine Hadida, Jesus Moreno, Corey Anderson, 2014 .

Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809

P. Negulescu, P. Grootenhuis, J. Wine, 2011, Proceedings of the National Academy of Sciences.

Rescue of DeltaF508-CFTR trafficking and gating in human cystic fibrosis airway primary cultures by small molecules.

James Rader, P. Negulescu, T. Knapp, 2006, American journal of physiology. Lung cellular and molecular physiology.

Fluorous Synthesis: A Fluorous‐Phase Strategy for Improving Separation Efficiency in Organic Synthesis

P. Wipf, A. Studer, Sabine Hadida, 1997 .

Regioselective Synthesis of 3‐Substituted Indoles: 3‐Ethylindole

Sabine Hadida, S. Sathyanarayana, J. Bosch, 2003 .

REGIOSELECTIVE SYNTHESIS OF 3-SUBSTITUTED INDOLES : 3-ETHYLINDOLE (1H-INDOLE, 3-ETHYL-)

Sabine Hadida, S. Sathyanarayana, J. Bosch, 1997 .

Pharmacological Rescue of Mutant CFTR Function for the Treatment of Cystic Fibrosis

P. Grootenhuis, Sabine Hadida, F. V. Goor, 2008 .

Discovery of N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide (VX-770, ivacaftor), a potent and orally bioavailable CFTR potentiator.

Jinglan Zhou, P. Negulescu, P. Grootenhuis, 2014, Journal of medicinal chemistry.

An efficient synthesis of 2-(2-pyridyl)indoles by palladium(0)-catalyzed heteroarylation

Sabine Hadida, J. Bosch, M. Amat, 1993 .

A new synthetic entry to the indolo[2,3-a]quinolizidine system. Electrophilic cyclizations on the indole ring from 2-(2-piperidyl)indoles

Sabine Hadida, S. Sathyanarayana, J. Bosch, 1996 .

An Efficient Synthesis of 2‐(2‐Pyridyl)indoles by Palladium(0)‐ Catalyzed Heteroarylation.

Sabine Hadida, J. Bosch, M. Amat, 1993 .

A New Synthetic Entry to the Indolo(2,3-a)quinolizidine System. Electrophilic Cyclizations on the Indole Ring from 2-(2-Piperidyl) indoles.

Sabine Hadida, S. Sathyanarayana, J. Bosch, 1996 .

Abnormal Pummerer cyclizations on the indole ring

Sabine Hadida, J. Bosch, M. Amat, 1996 .

Direct synthesis of trimethyl(2-phenoxyethyl)silanes from aromatic fluorides

Scott Grecian, Sabine Hadida, S. D. Warren, 2005 .

CFTR Modulators for the Treatment of Cystic Fibrosis

P. Grootenhuis, Sabine Hadida, F. V. Goor, 2010 .

Rescue of the protein folding defect in cystic fibrosis in vitro by the investigational small molecule, VX-809

P. Negulescu, P. Grootenhuis, J. Wine, 2010 .

Chapter Twenty-Four – Case History: Kalydeco® (VX-770, Ivacaftor), a CFTR Potentiator for the Treatment of Patients with Cystic Fibrosis and the G551D-CFTR Mutation

P. Grootenhuis, Sabine Hadida, K. Dinehart, 2014 .