Ashvani K. Singh

发表

Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770

Jinglan Zhou, P. Negulescu, P. Grootenhuis, 2009, Proceedings of the National Academy of Sciences.

Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770

P. Negulescu, P. Grootenhuis, F. van Goor, 2009, Proceedings of the National Academy of Sciences.

porcine vas deferens epithelium Neurotransmitter-stimulated ion transport by cultured

Ashvani K. Singh, R. Carlin, B. Schultz, 2016 .

Discovery and SAR of 4-Aminopyrrolidine-2-carboxylic Acid Correctors of CFTR for the Treatment of Cystic Fibrosis.

A. Bogdan, A. Swensen, Ashvani K. Singh, 2022, Bioorganic & medicinal chemistry letters.

Therapeutic approaches to CFTR dysfunction: From discovery to drug development.

N. Pedemonte, Ashvani K. Singh, D. Sheppard, 2017, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Bicarbonate and Chloride Secretion in Calu-3 Human Airway Epithelial Cells

Ashvani K. Singh, R. Frizzell, R. Bridges, 1999, The Journal of general physiology.

Mycoplasma pulmonis Inhibits Electrogenic Ion Transport across Murine Tracheal Epithelial Cell Monolayers

Ashvani K. Singh, R. Bridges, G. Cassell, 1998, Infection and Immunity.

Synthesis of novel 6-aza-B- and 11-aza-C-homoestranes as antifertility agents

M. Singh, Ashvani K. Singh, I. Dwivedy, 1993, Steroids.

Rescue of DeltaF508-CFTR trafficking and gating in human cystic fibrosis airway primary cultures by small molecules.

James Rader, P. Negulescu, T. Knapp, 2006, American journal of physiology. Lung cellular and molecular physiology.

Biological Characterization of F508delCFTR Protein Processing by the CFTR Corrector ABBV-2222/GLPG2222

C. Tse, D. Cyr, A. Swensen, 2019, The Journal of Pharmacology and Experimental Therapeutics.

Transepithelial impedance analysis of chloride secretion.

Ashvani K. Singh, R. Frizzell, R. Bridges, 2002, Methods in molecular medicine.

Identification of GLPG/ABBV-2737, a Novel Class of Corrector, Which Exerts Functional Synergy With Other CFTR Modulators

L. Nelles, P. Stouten, Ashvani K. Singh, 2019, Front. Pharmacol..

Discovery of 4-[(2R,4R)-4-({[1-(2,2-Difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl}amino)-7-(difluoromethoxy)-3,4-dihydro-2H-chromen-2-yl]benzoic Acid (ABBV/GLPG-2222), a Potent Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Corrector for the Treatment of Cystic Fibrosis.

A. Bogdan, C. Tse, A. Swensen, 2018, Journal of medicinal chemistry.

Novel Pseudomonas aeruginosa Quorum-Sensing Inhibitors Identified in an Ultra-High-Throughput Screen

E. Greenberg, R. Heim, M. Schuster, 2006, Antimicrobial Agents and Chemotherapy.

Transepithelial fluctuation analysis of chloride secretion.

Ashvani K. Singh, R. Bridges, W. van Driessche, 2004, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Stimulation of Cl 2 Secretion by Chlorzoxazone 1

J. Pilewski, Ashvani K. Singh, R. Bridges, 2000 .

Discovery of ABBV/GLPG-3221, a Potent Corrector of CFTR for the Treatment of Cystic Fibrosis.

A. Bogdan, C. Tse, A. Swensen, 2019, ACS medicinal chemistry letters.

Novel Correctors and Potentiators Enhance Translational Readthrough in CFTR Nonsense Mutations

Ashvani K. Singh, S. Rowe, K. Conrath, 2021, American Journal of Respiratory Cell and Molecular Biology.

Inhibitory effect of silibinin on ligand binding to erbB1 and associated mitogenic signaling, growth, and DNA synthesis in advanced human prostate carcinoma cells

R. Agarwal, Ashvani K. Singh, C. Agarwal, 2001, Molecular carcinogenesis.

Molecular Physiology and Pharmacology of the Cystic Fibrosis Transmembrane Conductance Regulator

N. Pedemonte, Ashvani K. Singh, D. Sheppard, 2020 .

Stimulation of Cl(-) secretion by chlorzoxazone.

J. Pilewski, A. K. Singh, Ashvani K. Singh, 2000, The Journal of pharmacology and experimental therapeutics.

Inhibition of intestinal Cl- secretion by clotrimazole: direct effect on basolateral membrane K+ channels.

A. K. Singh, Ashvani K. Singh, R. Frizzell, 1997, The American journal of physiology.

Comparison of-nitro versus-amino 4, 4′-substituents of disulfonic stilbenes as chloride channel blockers

Ashvani K. Singh, R. Bridges, C. Venglarik, 1994, Molecular and Cellular Biochemistry.

Novel Correctors and Potentiators Enhance Functional Rescue of CFTR Nonsense Mutation Translational Readthrough.

Ashvani K. Singh, S. Rowe, K. Conrath, 2021, American journal of respiratory cell and molecular biology.