G. Shearer

发表

HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells.

D. Fuchs, A. Boasso, J. Herbeuval, 2007, Blood.

Frequent detection and isolation of cytopathic retroviruses (HTLV-III) from patients with AIDS and at risk for AIDS.

B. Haynes, R. Redfield, M. Kaplan, 1984, Science.

T Lymphocyte-Directed Gene Therapy for ADA− SCID: Initial Trial Results After 4 Years

S. Rosenberg, W. Anderson, M. Clerici, 1995, Science.

Amendment to Clinical Research Project. Project 90-C-195. April 1, 1993. Treatment of severe combined immunodeficiency disease (SCID) due to adenosine deaminase deficiency with autologous lymphocytes transduced with a human ADA gene.

W. Anderson, M. Clerici, K. Weinberg, 1999, Human gene therapy.

The self determinants recognized by human virus-immune T cells can be distinguished from the serologically defined HLA antigens.

G. Shearer, W. Biddison, S. Shaw, 1980, Journal of immunology.

Normal immune function of monocyte-derived dendritic cells from HIV-infected individuals: implications for immunotherapy.

H. Kessler, C. Chougnet, A. Blauvelt, 1999, Journal of immunology.

HIV-1 antibody serum negativity with urine positivity

M. Clerici, L. Lutwick, G. Shearer, 1993, The Lancet.

The Th1-Th2 hypothesis of HIV infection: new insights.

M. Clerici, G. Shearer, 1994, Immunology today.

Binding of glycoprotein 120 and peptides from the HIV-1 envelope by autoantibodies in mice with experimentally induced systemic lupus erythematosus and in patients with the disease.

J. Berzofsky, A. Waisman, E. Mozes, 1994, AIDS Research and Human Retroviruses.

Modulation of Inflammation and Immunity by Cyclic AMP

H. Bourne, K. Melmon, L. Lichtenstein, 1974 .

Common epitope in human immunodeficiency virus (HIV) I-GP41 and HLA class II elicits immunosuppressive autoantibodies capable of contributing to immune dysfunction in HIV I-infected individuals.

M. Clerici, B. Golding, G. Shearer, 1989, The Journal of clinical investigation.

Functional dichotomy of CD4+ T helper lymphocytes in asymptomatic human immunodeficiency virus infection

M. Clerici, G. Shearer, Daniel Lucey, 1991, European journal of immunology.

CD4+ T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis.

J. Lifson, C. Chougnet, J. Grivel, 2005, Blood.

Non-toxic inhibition of HIV-1 replication with silver–copper nanoparticles

C. Eddy, A. Boasso, Andrew W. Hardy, 2010, Medicinal Chemistry Research.

HIV-Induced Type I Interferon and Tryptophan Catabolism Drive T Cell Dysfunction Despite Phenotypic Activation

A. Boasso, Andrew W. Hardy, S. Anderson, 2008, PloS one.

HIV-1 immunopathogenesis: how good interferon turns bad.

J. Herbeuval, G. Shearer, 2007, Clinical immunology.

bloodjournal.hematologylibrary.org at PENN STATE UNIVERSITY on February 20, 2013. For personal use

J. Lifson, C. Chougnet, L. Havekes, 2004 .

Treatment of Severe Combined Immunodeficiency Disease (SCID) due to Adenosine Deaminase Deficiency with CD34+ Selected Autologous Peripheral Blood Cells Transduced with a Human ADA Gene (Amendment). National Institutes of Health

W. Anderson, M. Clerici, R. Morgan, 1993 .

Immunologic and virologic evaluation after influenza vaccination of HIV‐1‐infected patients

H. Kessler, D. Chernoff, G. Shearer, 1997, AIDS.

Exposure to Human Immunodeficiency Virus Type I-Specific T Helper Cell Responses before Detection of Infection by Polymerase Chain Reaction and Serum Antibodies

J. Berzofsky, M. Clerici, C. Tacket, 1991 .

Regulatory T cells (Treg) and HIV/AIDS: summary of the September 7-8, 2006 workshop.

C. Chougnet, G. Shearer, 2007, AIDS research and human retroviruses.

CELLULAR BASIS OF THE GENETIC CONTROL OF IMMUNE RESPONSES TO SYNTHETIC POLYPEPTIDES

M. Sela, E. Mozes, G. Shearer, 1970, The Journal of experimental medicine.

Cellular basis of the genetic control of immune responses to synthetic polypeptides. II. Frequency of immunocompetent precursors specific for two distinct regions within (Phe, G)-Pro--L, a synthetic polypeptide derived from multichain polyproline, in inbred mouse strains.

M. Sela, E. Mozes, G. Shearer, 1971 .

Cell-mediated lympholysis of trinitrophenyl-modified autologous lymphocytes. Effector cell specificity to modified cell surface components controlled by H-2K and H-2D serological regions of the murine major histocompatibility complex

G. Shearer, T. Rehn, C. Garbarino, 1975, The Journal of experimental medicine.

Role of the Murine Major Histocompatibility Complex in the Specificity of in vitro T‐Cell‐Mediated Lympholysis Against Chemically‐Modified Autologous Lymphocytes

G. Shearer, T. Rehn, Anne‐Marie Schmht‐Verhulst, 1976, Transplantation reviews.

Infection of HIV-1 transgenic mice with Mycobacterium avium induces the expression of infectious virus selectively from a Mac-1-positive host cell population.

A. Sher, C. Chougnet, M. Schito, 1999, Journal of immunology.

Role of T‐Cell Derived Cytokines in the Downregulation of Immune Responses in Parasitic and Retroviral Infection

J. Berzofsky, A. Sher, M. Clerici, 1992, Immunological reviews.

Malaria infection induces virus expression in human immunodeficiency virus transgenic mice by CD4 T cell-dependent immune activation.

A. Sher, C. Chougnet, M. Schito, 2001, The Journal of infectious diseases.

Viremia control following antiretroviral treatment and therapeutic immunization during primary SIV251 infection of macaques

D. Watkins, J. Altman, D. Venzon, 2000, Nature Medicine.

In vitro T cell function, delayed-type hypersensitivity skin testing, and CD4+ T cell subset phenotyping independently predict survival time in patients infected with human immunodeficiency virus.

M. Clerici, C. Hendrix, M. Dolan, 1995, The Journal of infectious diseases.

Hemolytic plaque formation by leukocytes in vitro. Control by vasoactive hormones.

H. Bourne, K. Melmon, G. Shearer, 1974, The Journal of clinical investigation.

Changes in T-helper cell function in human immunodeficiency virus- infected children during didanosine therapy as a measure of antiretroviral activity

D. Venzon, M. Clerici, G. Shearer, 1992 .

Changes in T-helper cell function in human immunodeficiency virus-infected children during didanosine therapy as a measure of antiretroviral activity.

D. Venzon, M. Clerici, G. Shearer, 1992, Blood.

Induction and Measurement of Cytotoxic T Lymphocyte Activity

G. Shearer, A. Brooks, A. Livingstone, 2006, Current protocols in immunology.

Analysis of the Costimulatory Requirements for Generating Human Virus-Specific in Vitro T Helper and Effector Responses

G. Shearer, C. M. Trubey, V. Blazevic, 2001, Journal of Clinical Immunology.

Influenza virus-stimulated generation of anti-human immunodeficiency virus (HIV) activity after influenza vaccination in HIV-infected individuals and healthy control subjects.

D. Venzon, D. Liewehr, S. Anderson, 2001, The Journal of infectious diseases.

Inhibition of Human Immunodeficiency Virus Type 1 Replication prior to Reverse Transcription by Influenza Virus Stimulation

M. Dolan, G. Shearer, L. Pinto, 2000, Journal of Virology.

Generation of alloantigen-stimulated anti-human immunodeficiency virus activity is associated with HLA-A*02 expression.

S. Steinberg, D. Liewehr, G. Shearer, 2001, The Journal of infectious diseases.

T helper cell dysfunction in systemic lupus erythematosus (SLE): Relation to disease activity

Matthew W. Miller, M. Petri, G. Shearer, 1994, Journal of Clinical Immunology.

Interleukin 2 production in vitro by peripheral lymphocytes in response to human papillomavirus-derived peptides: correlation with cervical pathology.

David R. Scott, M. Carrington, J. Berzofsky, 1996, Cancer research.

Self-thyroid epithelial cell (TEC)-reactive CD8+ T cell lines/clones derived from autoimmune thyroiditis lesions. They recognize self-thyroid antigens directly on TEC to exhibit T helper cell 1-type lymphokine production and cytotoxicity against TEC.

G. Shearer, H. Fujiwara, S. Sugihara, 1995, Journal of immunology.

Immunization with subunit human immunodeficiency virus vaccine generates stronger T helper cell immunity than natural infection

J. Berzofsky, M. Clerici, C. Tacket, 1991, European journal of immunology.

Effects of total pathogen burden on coronary artery disease risk and C-reactive protein levels.

A. Quyyumi, S. Epstein, G. Shearer, 2000, The American journal of cardiology.

Multiple defects of T helper cell function in newly diagnosed patients with Hodgkin's disease.

D. Venzon, M. Clerici, G. Shearer, 1994, European journal of cancer.

Monocyte Cytokine Profile and Surface Involves Soluble Factor(s) That Alters Human Glioma-Induced Immunosuppression

J. Coligan, T. Roszman, J. Shuman, 2013 .

Markers Monocyte Cytokine Profile and Surface Involves Soluble Factor ( s ) That Alters Human Glioma-Induced Immunosuppression Gene

J. Coligan, T. Roszman, J. Shuman, 1999 .

Development of disease and virus recovery in transgenic mice containing HIV proviral DNA.

J. Leonard, G. Shearer, J. Abramczuk, 1988, Science.

Cytotoxic T cell interactions with antigen. Potential relevance for drug-related lupus.

G. Shearer, S. Shaw, 1981, Arthritis and rheumatism.

Effect of indoleamine 2,3-dioxygenase on induction of experimental autoimmune encephalomyelitis

J. Ward, G. Shearer, K. Sakurai, 2002, Journal of Neuroimmunology.

Antiretroviral activity of the aminothiol WR1065 against Human Immunodeficiency virus (HIV-1) in vitro and Simian Immunodeficiency virus (SIV) ex vivo

Andrew W. Hardy, G. Shearer, M. Poirier, 2009, AIDS research and therapy.

Cellular immunology of HIV infection

M. Clerici, G. Shearer, 1991 .

Induction and Measurement of Cytotoxic T Lymphocyte Activity

G. Shearer, A. Brooks, A. Livingstone, 1997, Current protocols in immunology.

Abrogation of hybrid resistance to bone marrow engraftment by graft-vs-host-induced immune deficiency.

G. Shearer, F. Hakim, 1986, Journal of immunology.

Immunogenic function of macrophages: in vitro production of antibodies to a hapten-carrier conjugate.

A. Globerson, G. Shearer, M. Feldman, 1972, Cellular immunology.

Conversion with Polynucleotides of a Genetically Controlled Low Immune Response to a High Response in Mice Immunized with a Synthetic Polypeptide Antigen

M. Sela, E. Mozes, G. Shearer, 1971 .

DIFFERENTIATION OF POTENTIALLY IMMUNOCOMPETENT CELLS IN THE MOUSE.

G. Shearer, G. Cudkowicz, 1969 .

Fatal Pancreatitis in Simian Immunodeficiency Virus SIVmac251-Infected Macaques Treated with 2′,3′-Dideoxyinosine and Stavudine following Cytotoxic-T-Lymphocyte-Associated Antigen 4 and Indoleamine 2,3-Dioxygenase Blockade

D. Fuchs, J. Héraud, A. Hryniewicz, 2011, Journal of Virology.

Influenza virus-specific cytotoxic T cells are restricted by multiple HLA-A3-related self antigens: evidence for recognition of distinct self structures in conjunction with different foreign antigens.

G. Shearer, W. Biddison, S. Shaw, 1981, Journal of immunology.

Virus-immune cytotoxic T cells recognize structural differences between serologically indistinguishable HLA-A2 molecules.

J. Strominger, M. Krangel, G. Shearer, 1980, Human immunology.

Multideterminant regions of the HIV-1 envelope with sites seen by murine and human helper T cells: circumventing the MHC restriction problem

C. DeLisi, J. Cornette, K. Cease, 1990 .

Do regulatory T-cells play a role in AIDS pathogenesis?

C. Chougnet, J. Andersson, M. Vaccari, 2006, AIDS reviews.

Major histocompatibility complex restricted cell-mediated immunity.

G. Shearer, A. Schmitt‐Verhulst, A. Schmitt-Verhulst, 1977, Advances in immunology.

Regulation of influenza virus-specific cytotoxic T cell responses by monoclonal antibody to a human T cell differentiation antigen.

T. Chang, G. Shearer, W. Biddison, 1981, Journal of immunology.

Inhibition of activation-induced programmed cell death and restoration of defective immune responses of HIV+ donors by cysteine protease inhibitors.

M. Clerici, P. Henkart, A. Sarin, 1994, Journal of immunology.

Analysis of T helper and antigen-presenting cell functions in cord blood and peripheral blood leukocytes from healthy children of different ages.

M. Clerici, G. Shearer, R. Baker, 1993, The Journal of clinical investigation.

Regulation of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA-synthetase by CTLA-4-Fc in human CD4+ T cells.

A. Boasso, J. Herbeuval, Andrew W. Hardy, 2005, Blood.

The effect of IL-12 on clinical and laboratory aspects of experimental SLE in young and aging mice

H. Zinger, E. Mozes, G. Shearer, 2003, Experimental Gerontology.

In vitro analysis of cell-mediated immunity: clinical relevance.

M. Clerici, G. Shearer, 1994, Clinical chemistry.

Alloimmunization as an AIDS vaccine?

M. Clerici, A. Dalgleish, G. Shearer, 1993, Science.

Kinetics of cytokine production in experimental systemic lupus erythematosus: involvement of T helper cell 1/T helper cell 2-type cytokines in disease.

F. Kalush, E. Mozes, G. Shearer, 1997, Journal of immunology.

Functional T lymphocyte immune deficiency in a population of homosexual men who do not exhibit symptoms of acquired immune deficiency syndrome.

G. Shearer, W. Biddison, L. J. Joseph, 1984, The Journal of clinical investigation.

Th1/Th2 changes in aging.

G. Shearer, Gene M. Shearer, 1997, Mechanisms of ageing and development.

The human antimurine xenogeneic cytotoxic response. I. Dependence on responder antigen-presenting cells.

G. Shearer, R. Gress, P. Lucas, 1990, Journal of immunology.

Host Response to Cytomegalovirus Infection as a Determinant of Susceptibility to Coronary Artery Disease: Sex-Based Differences in Inflammation and Type of Immune Response

F. Marincola, A. Quyyumi, S. Epstein, 2000, Circulation.

Human cytotoxic T-cell responses to type A and type B influenza viruses can be restricted by different HLA antigens. Implications for HLA polymorphism and genetic regulation

G. Shearer, W. Biddison, S. Shaw, 1980, The Journal of experimental medicine.

Alloantigen recognition in utero: dual advantage for the fetus?

G. Shearer, M. Rugeles, 2004, Trends in immunology.

Alloimmunization for immune-based therapy and vaccine design against HIV/AIDS.

M. Clerici, G. Shearer, L. Pinto, 1999, Immunology today.

Mother-to-infant transmission of HIV type 1: role of major histocompatibility antigen differences.

G. Shearer, B. Mittleman, 1996, AIDS research and human retroviruses.

Ribonuclease is partly responsible for the HIV-1 inhibitory effect activated by HLA alloantigen recognition

S. Rybak, G. Shearer, M. Rugeles, 2003, AIDS.

Quantifying the strength and durability of induced immunity to HIV infection in women engaging in unprotected sexual contacts with infected men

G. Shearer, I. Kramer, 2002 .

Anti-CCR5 antibodies in sera of HIV-positive individuals.

H. Kessler, S. Anderson, M. Dolan, 2001, Human immunology.

Increased levels of anti-CCR5 antibodies in sera from individuals immunized with allogeneic lymphocytes.

H. Kessler, J. V. Giorgi, G. Shearer, 2000, AIDS.

Comparison of spinal fluid beta 2-microglobulin levels with CD4+ T cell count, in vitro T helper cell function, and spinal fluid IgG parameters in 163 neurologically normal adults infected with the human immunodeficiency virus type 1.

S. A. McGuire, M. Clerici, C. Hendrix, 1991, The Journal of infectious diseases.

T-cell interactions in autoimmunity: insights from a murine model of graft-versus-host disease.

G. Shearer, C. Via, 1988, Immunology today.

Lamivudine in Children with Human Immunodeficiency Virus Infection: A Phase 1/11 Study

D. Venzon, F. Balis, G. Shearer, 2010 .

IFN-α Acts on T-Cell Receptor-Triggered Human Peripheral Leukocytes to Up-Regulate CCR5 Expression on CD4+ and CD8+ T Cells

H. Fujiwara, G. Shearer, T. Hamaoka, 2001, Journal of Clinical Immunology.

Regulatory T-Cell Markers, Indoleamine 2,3-Dioxygenase, and Virus Levels in Spleen and Gut during Progressive Simian Immunodeficiency Virus Infection

D. Fuchs, C. Chougnet, A. Hryniewicz, 2007, Journal of Virology.

How does indoleamine 2,3-dioxygenase contribute to HIV-mediated immune dysregulation.

A. Boasso, G. Shearer, 2007, Current drug metabolism.

Antigen-presenting cells in HIV pathogenesis and therapy: summary of the October 17-18, 2002, Think Tank meeting.

C. Chougnet, G. Shearer, A. Landay, 2002, Clinical immunology.

CD8+ T cells from mice vaccinated against Toxoplasma gondii are cytotoxic for parasite-infected or antigen-pulsed host cells.

A. Sher, E. Denkers, R. Gazzinelli, 1991, Journal of immunology.

CELL FRACTIONATION OVER CHARGED COLUMNS

M. Sela, E. Mozes, G. Shearer, 2003 .

IN VITRO INDUCTION OF THYMUS‐DERIVED CELLMEDIATED CYTOTOXICITY TO TRINITROPHENOLMODIFIED SYNGENEIC LYMPHOCYTE SURFACE PROTEINS

G. Shearer, 1975, Annals of the New York Academy of Sciences.

In vitro correction of antigen-induced immune suppression: effects of histamine, dibutyryl cyclic AMP and cholera enterotoxin.

H. Bourne, K. Melmon, E. Mozes, 1974, Cellular immunology.

Pharmacologic Regulation of Antibody Release in Vitro: Effects of Vasoactive Amines and Cyclic AMP

H. Bourne, K. Melmon, G. Shearer, 1974 .

THE ROLE OF THYMOCYTES AND BONE MARROW CELLS IN DEFINING THE RESPONSE TO THE DINITROPHENYL HAPTEN ATTACHED TO POSITIVELY AND NEGATIVELY CHARGED SYNTHETIC POLYPEPTIDE CARRIERS

M. Sela, E. Mozes, G. Shearer, 1973, The Journal of experimental medicine.

REGULATION OF ANTIBODY RESPONSE BY CELLS EXPRESSING HISTAMINE RECEPTORS

K. Melmon, M. Sela, G. Shearer, 1972, The Journal of experimental medicine.

B cell activation in vivo by nonantigen-specific interaction with T cells. Frequency of immune responses increased by immunization with two antigens.

G. Shearer, D. Trizio, G. Cudkowicz, 1972 .

B CELL ACTIVATION IN VIVO BY NONANTIGEN-SPECIFIC INTERACTION WITH T CELLS

G. Shearer, D. Trizio, G. Cudkowicz, 1972, The Journal of experimental medicine.

Other factors to consider in infantile AIDS.

G. Shearer, W. Parks, G. Scott, 1984, The New England journal of medicine.

Significance of the major histocompatibility complex as assessed by T-cell-mediated lympholysis involving syngeneic stimulating cells.

G. Shearer, A. Schmitt‐Verhulst, T. Rehn, 1977, Contemporary topics in immunobiology.

Large-cell anaplastic lymphoma-specific translocation in Hodgkin's disease.

G. Shearer, Daniel Lucey, 1995, Lancet.

Introduction: Back to basics: mucosal immunity and novel HIV vaccine concepts

A. Haase, J. Andersson, G. Shearer, 2009, Journal of internal medicine.

Abnormalities of Immune Regulation in Human Immunodeficiency Virus Infection

M. Clerici, G. Shearer, 1993, Pediatric Research.

Separation of specific antibody-forming mouse cells by their adherence to insolubilized endogenous hormones.

H. Bourne, K. Melmon, G. Shearer, 1974, The Journal of clinical investigation.

Regulation of influenza virus-specific

G. Shearer, Wen Chang, 2001 .

Preparative separation of human T cells reactive with the OKT4 monoclonal antibody.

G. Shearer, S. Sharrow, W. Biddison, 1981, International journal of immunopharmacology.

Regulatory T cell markers , indoleamine ( 2 , 3 )-dioxygenase and virus levels in spleen and gut during progressive SIV infection

D. Fuchs, C. Chougnet, A. Hryniewicz, 2007 .

Murine Graft‐versus‐Host Disease as a Model for the Development of Autoimmunity

G. Shearer, C. Via, 1988, Annals of the New York Academy of Sciences.

Effect of cyclosporin A on T cell immunity I. Dose‐dependent suppression of different murine T helper cell pathways

M. Fukuzawa, G. Shearer, M. Fukuzawa, 1989, European journal of immunology.

Functional heterogeneity of L3T4+ T cells in MRL-lpr/lpr mice. L3T4+ T cells suppress major histocompatibility complex-self-restricted L3T4+ T helper cell function in association with autoimmunity

G. Shearer, C. Via, 1988, The Journal of experimental medicine.

The T Helper Cell Shift in AIDS

G. Shearer, Professor Mario Clerici, 1995, Clinical Immunotherapeutics.

Hapten specific TNP-reactive cytotoxic effector cells using epidermal cells as targets.

G. Shearer, R. Levy, S. Katz, 1981, The Journal of investigative dermatology.

Cytokines in immune regulation/pathogenesis in HIV infection.

J. Berzofsky, M. Clerici, P. Henkart, 1995, Ciba Foundation symposium.

Pilot study of the immunologic effects of recombinant human growth hormone and recombinant insulin‐like growth factor in HIV‐infected patients

D. Longo, M. Baseler, D. Venzon, 1998, AIDS.

Trinitrophenyl modification of H-2k and H-2b spleen cells results in enhanced serological detection of Kk-like determinants

G. Shearer, D. Segal, R. Levy, 1984, The Journal of experimental medicine.

Lymphocyte Content and Proliferative Capacity of Serially Transplanted Mouse Bone Marrow

G. Shearer, A. Upton, G. Cudkowicz, 1964, Nature.

B7-H1 is Upregulated in HIV infection and is a Novel Surrogate Marker of Disease Progression. running head: B7-H1 in HIV infection

R. Maserati, Lieping Chen, M. Clerici, 2002 .

Induction and Measurement of Cytotoxic T Lymphocyte Activity

G. Shearer, A. Livingstone, John Wonderlich, 1997 .

Common sequence in HIV 1 GP41 and HLA class II beta chains can generate crossreactive autoantibodies with immunosuppressive potential early in the course of HIV 1 infection.

J. Goedert, M. Clerici, B. Golding, 1991, Advances in experimental medicine and biology.

In vitro restoration of T cell immune function in human immunodeficiency virus-positive persons: effects of interleukin (IL)-12 and anti-IL-10.

J. Berzofsky, M. Clerici, H. Kessler, 1996, The Journal of infectious diseases.

Role of IL12 in HIV disease/AIDS.

M. Clerici, C. Chougnet, G. Shearer, 1995, Research in immunology.

T cell subpopulations required for the human cytotoxic T lymphocyte response to influenza virus: evidence for T cell help.

G. Shearer, S. Sharrow, W. Biddison, 1981, Journal of immunology.

HIV turns plasmacytoid dendritic cells (pDC) into TRAIL-expressing killer pDC and down-regulates HIV coreceptors by Toll-like receptor 7-induced IFN-α

D. Graham, J. Herbeuval, Andrew W. Hardy, 2007, Proceedings of the National Academy of Sciences.

Differential expression of IFN-alpha and TRAIL/DR5 in lymphoid tissue of progressor versus nonprogressor HIV-1-infected patients.

M. Kruhlak, J. Andersson, A. Boasso, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Ribonucleases in HIV type 1 inhibition: effect of recombinant RNases on infection of primary T cells and immune activation-induced RNase gene and protein expression.

S. Rybak, A. Boasso, Andrew W. Hardy, 2006, AIDS research and human retroviruses.

TLR Activation Pathways in HIV-1–Exposed Seronegative Individuals

M. Clerici, M. Biasin, S. Lo Caputo, 2010, The Journal of Immunology.

Graft-Versus-Host-Associated Immune Suppression Involves in Vivo Recognition of Allogeneic I-A Determinants

G. Shearer, R. Levy, 1983 .

Cytokine profiles in HIV type 1 disease and protection.

M. Clerici, G. Shearer, 1998, AIDS research and human retroviruses.

An immunoendocrinological hypothesis of HIV infection

M. Clerici, G. Norbiato, G. Shearer, 1994, The Lancet.

Human immunodeficiency virus type 1 (HIV-1)-seronegative injection drug users at risk for HIV exposure have antibodies to HLA class I antigens and T cells specific for HIV envelope.

J. Berzofsky, G. Shearer, A. Cosma, 1996, The Journal of infectious diseases.

Can cytotoxic T cells recognize self determinants on molecules lacking polymorphic MHC self determinants.

G. Shearer, R. Levy, 1982, Immunology today.

Cell-mediated lympholysis to H-2-matched target cells modified with a series of nitrophenyl compounds

G. Shearer, J. Inman, T. Rehn, 1976, The Journal of experimental medicine.

Cell-mediated lympholysis of N-(3-nitro-4-hydroxy-5-iodophenylacetyl)- beta-anaylglycylglycyl-modified autologous lymphocytes. Effector cell specificity to modified cell surface components controlled by the H-2K and H-2D serological regions of the murine major histocompatibility complex

G. Shearer, J. Inman, H. Koren, 1976, The Journal of experimental medicine.

BIFUNCTIONAL HISTOCOMPATIBILITY-LINKED REGULATION OF CELL MEDIATED LYMPHOLYSIS TO MODIFIED AUTOLOGOUS CELL SURFACE COMPONENTS

G. Shearer, A. Schmitt‐Verhulst, T. Rehn, 1976 .

B-Cell Alloantigens Determined by the H-2 Linked Ir Region Are Associated with Mixed Lymphocyte Culture Stimulation

D. Sachs, G. Shearer, E. Lozner, 1974, Science.

Accessory cell function in asymptomatic human immunodeficiency virus-infected patients.

M. Clerici, G. Shearer, R. Boswell, 1990, Clinical immunology and immunopathology.

Synergistic role of CD4+ and CD8+ T lymphocytes in IFN-gamma production and protective immunity induced by an attenuated Toxoplasma gondii vaccine.

A. Sher, R. Gazzinelli, G. Shearer, 1991, Journal of immunology.

Cell adhesiveness is related to tumorigenicity in malignant lymphoid cells

M. Gottesman, G. Shearer, J. Hochman, 1984, The Journal of cell biology.

Vaccine strategies: selective elicitation of cellular or humoral immunity?

M. Clerici, G. Shearer, 1997, Trends in biotechnology.

The breakdown of the cytokine network subsequent to human immunodeficiency virus infection

M. Clerici, G. Shearer, D. Trabattoni, 1995, Mediators of inflammation.

Immunologic characterization of children vertically infected with human immunodeficiency virus, with slow or rapid disease progression.

M. Clerici, G. Shearer, N. Principi, 1995, The Journal of pediatrics.

TH1 and TH2 Type Responses in HIV Infection

M. Clerici, G. Shearer, Robert L. Coffmann, 1993 .

Regulation of graft‐versus‐host‐reaction by Mlsa‐reactive donor T cells

S. Muluk, G. Shearer, F. Hakim, 1992, European journal of immunology.

How human immunodeficiency virus ravages the immune system.

M. Clerici, G. Shearer, 1992 .

SELECTIVE EXPANSION OF H‐2 RESTRICTED CYTOTOXIC T LYMPHOCYTES TO TNP‐SELF BY INJECTION OF TRINITROBENZENE SULFONATE

G. Shearer, R. Levy, 1982, Annals of the New York Academy of Sciences.

Changes in interleukin-2 and interleukin-4 production in asymptomatic, human immunodeficiency virus-seropositive individuals.

D. Venzon, M. Clerici, T. Wynn, 1993, The Journal of clinical investigation.

TYPE 1 AND TYPE 2 RESPONSES IN HIV INFECTION AND EXPOSURE

M. Clerici, G. Shearer, 1996 .

Cellular immunity and a type 1 cytokine profile in protection against HIV infection and progression to AIDS.

M. Clerici, G. Shearer, 1994, Research in immunology.

A factor from CD8 cells of human immunodeficiency virus-infected patients suppresses HLA self-restricted T helper cell responses.

M. Clerici, G. Shearer, P. Pizzo, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Human in vitro allogeneic responses. Demonstration of three pathways of T helper cell activation.

M. Clerici, G. Tsokos, G. Shearer, 1990, Journal of immunology.

Cerebrospinal fluid cytokines in pediatric neuropsychiatric disease.

J. Rapoport, F. Castellanos, L. Jacobsen, 1997, Journal of immunology.

Autoimmunity and the acquired immune deficiency syndrome.

G. Shearer, C. Via, 1989, Current opinion in immunology.

Study of the effect of indoleamine 2,3-dioxygenase on murine mixed lymphocyte reactions and skin allograft rejection.

G. Shearer, K. Sakurai, J. Zou, 2002, Transplantation proceedings.

Demonstration of human T lymphotropic virus type I (HTLV-I)-specific T cell responses from seronegative and polymerase chain reaction-negative persons exposed to HTLV-I.

Bill M. Maloney, J. Berzofsky, A. Kermode, 1994, The Journal of infectious diseases.

Autoimmune thyroiditis induced in mice depleted of particular T cell subsets. Characterization of thyroiditis-inducing T cell lines and clones derived from thyroid lesions.

G. Shearer, H. Fujiwara, S. Sugihara, 1993, Journal of immunology.

Genetic control of immune responses.

E. Mozes, G. Shearer, 1972, Current topics in microbiology and immunology.

tryptophanyl-tRNA-synthetase by CTLA-4-Fc in human CD4+ T cells Regulation of indoleamine 2,3-dioxygenase and

A. Boasso, J. Herbeuval, Andrew W. Hardy, 2013 .

Effect of metacycloprodigiosin, an inhibitor of killer T cells on murine skin and heart transplants.

M. Miller, K. Nagai, G. Shearer, 1996, The Journal of antibiotics.

Antigenic competition and genetic control of the immune response. A hypothesis for intramolecular competition.

M. Taussig, M. Sela, E. Mozes, 1973, Cellular immunology.

CELLULAR BASIS OF THE GENETIC CONTROL OF IMMUNE RESPONSES TO SYNTHETIC POLYPEPTIDES

M. Sela, E. Mozes, G. Shearer, 1971, The Journal of experimental medicine.

Are Some People Protected Against HIV Infection

M. Clerici, M. Biasin, G. Shearer, 2012 .

Protective immunity against HIV infection: has nature done the experiment for us?

M. Clerici, G. Shearer, 1996, Immunology today.

Effect of a recombinant CD4-IgG on in vitro T helper cell function: data from a phase I/II study of patients with AIDS.

M. Clerici, S. Broder, C. Hendrix, 1993, The Journal of infectious diseases.

Cytokine production patterns in cervical intraepithelial neoplasia: association with human papillomavirus infection.

D. Venzon, M. Clerici, G. Shearer, 1997, Journal of the National Cancer Institute.

The augmentation of in vitro and in vivo tumor-specific T cell-mediated immunity by amplifier T lymphocytes.

G. Shearer, H. Yamamoto, T. Hamaoka, 1980, Journal of immunology.

Cytotoxic T cells. Biology and relevance to disease.

G. Shearer, J. Battisto, J. Plate, 1988, Annals of the New York Academy of Sciences.

Alloantigen-stimulated anti-HIV activity.

G. Shearer, L. Pinto, D. Cohen, 1998, Blood.

IFN-alpha acts on T-cell receptor-triggered human peripheral leukocytes to up-regulate CCR5 expression on CD4+ and CD8+ T cells.

H. Fujiwara, G. Shearer, T. Hamaoka, 2001, Journal of clinical immunology.

THE EFFECT OF CYTOMEGALOVIRUS INFECTION ON THE HOST RESPONSE TO FOREIGN AND HAPTEN‐MODIFIED SELF HISTOCOMPATIBILITY ANTIGENS

G. Shearer, J. Grundy, 1984, Transplantation.

PLURIPOTENT STEM CELL FUNCTION OF THE MOUSE MARROW "LYMPHOCYTE".

G. Shearer, G. Cudkowicz, M. Bennett, 1964, Science.

Type 1/type 2 cytokine modulation of T-cell programmed cell death as a model for human immunodeficiency virus pathogenesis.

R. Coffman, M. Clerici, T. Wynn, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Effect of aging on cytokine production in normal and experimental systemic lupus erythematosus afflicted mice

A. Globerson, E. Mozes, G. Shearer, 1997, Mechanisms of Ageing and Development.

Historical perspective on HIV‐exposed seronegative individuals: has nature done the experiment for us?

M. Clerici, G. Shearer, 2010, The Journal of infectious diseases.

Role of cytotoxic T lymphocytes in the prevention of lupus-like disease occurring in a murine model of graft-vs-host disease.

G. Shearer, S. Sharrow, C. Via, 1987, Journal of immunology.

I. DIFFERENCES IN FREQUENCY OF SPLENIC PRECURSOR CELL~ SPECIFIC FOR A SYNTHETIC POLYPEPTIDE DERIVED FROM MULTICHAIN POLYPROLINE

M. Sela, E. Mozes, G. Shearer, 2003 .

CELLULAR BASIS O F THE G ENETIC CONTROL OF IMMUNE RESPONSES TO SYNTHETIC P OLYPEPTIDES I. DIFFERENCES IN FREQUENCY OF SPLENIC PRECURSOR CELL~ SPECIFIC FOR

M. Sela, E. Mozes, G. Shearer, 1970 .

Genetic analysis of experimentally induced lupus in mice.

D. Alling, M. Miller, H. Zinger, 1997, Clinical immunology and immunopathology.

Defective in vitro IL-2 production in lupus is an early but secondary event paralleling disease activity: Evidence from the murine parent-into-F1 model supports staging of IL-2 defects in human lupus

G. Shearer, C. Via, 2010, Autoimmunity.

Effect of cyclosporin A on T cell immunity II. Defective thymic education of CD4 T helper cell function in cyclosporin A‐treated mice

M. Fukuzawa, G. Shearer, S. Sharrow, 1989, European journal of immunology.

AIDS: an autoimmune pathologic model for the destruction of a subset of helper T lymphocytes.

G. Shearer, 1986, The Mount Sinai journal of medicine, New York.

Repopulation of host lymphohematopoietic systems by donor cells during graft-versus-host reaction in unirradiated adult F1 mice injected with parental lymphocytes.

G. Shearer, S. Sharrow, F. Hakim, 1991, Journal of immunology.

The prevalence of regulatory T cells in lymphoid tissue is correlated with viral load in HIV-infected patients.

N. Shire, C. Chougnet, J. Andersson, 2005, Journal of Immunology.

J. Lifson, C. Chougnet, J. Grivel, 2005, Blood.

Detection of three distinct patterns of T helper cell dysfunction in asymptomatic, human immunodeficiency virus-seropositive patients. Independence of CD4+ cell numbers and clinical staging.

M. Clerici, G. Shearer, Daniel Lucey, 1989, The Journal of clinical investigation.

Curing HIV/AIDS beyond hematopoietic stem cell transplant.

M. Clerici, D. Graham, A. Boasso, 2015, AIDS.

2,3-dioxygenase in plasmacytoid dendritic cells HIV inhibits CD4+ T-cell proliferation by inducing indoleamine

D. Fuchs, A. Boasso, J. Herbeuval, 2013 .

The hunt for an HIV vaccine: time to rethink recent failures

M. Clerici, A. Boasso, G. Shearer, 2008, The Lancet.

Alloimmunization as a strategy for vaccine design against HIV/AIDS.

T. Lehner, G. Shearer, O. Sharma, 2000, AIDS research and human retroviruses.

In vitro immunologic and virologic effects of interleukin 15 on peripheral blood mononuclear cells from normal donors and human immunodeficiency virus type 1-infected patients

R. Paxton, H. Kessler, G. Shearer, 1997, Clinical and diagnostic laboratory immunology.

Limiting dilution analysis of interleukin‐2‐producing T cells responsive to recall and alloantigens in human immunodeficiency virus‐infected and uninfected individuals

M. Clerici, R. Schulick, M. Dolan, 1993, European Journal of Immunology.

Helper T-cell responses in children infected with human immunodeficiency virus type 1.

M. Clerici, G. Shearer, P. Pizzo, 1991, The Journal of pediatrics.

Graft-vs-host reaction limited to a class II MHC difference results in a selective deficiency in L3T4+ but not in Lyt-2+ T helper cell function.

A. Singer, M. Moser, G. Shearer, 1987, Journal of immunology.

A model for the selective loss of major histocompatibility complex self-restricted T cell immune responses during the development of acquired immune deficiency syndrome (AIDS).

R. Redfield, K. Tung, S. Salahuddin, 1986, Journal of immunology.

Amelioration of experimental systemic lupus erythematosus (SLE) by retrovirus infection

E. Mozes, H. Morse, G. Shearer, 1996, Journal of Clinical Immunology.

Human herpesvirus 8 cellular immune responses in homosexual men.

J. Goedert, T. O'Brien, J. Palefsky, 1999, The Journal of infectious diseases.

Overactivation of plasmacytoid dendritic cells inhibits antiviral T-cell responses: a model for HIV immunopathogenesis.

D. Fuchs, M. Clerici, D. Graham, 2011, Blood.

AIDS therapy by blocking CD4+ cells

A. Singer, G. Shearer, 1986, Nature.

Restoration of HIV-specific cell-mediated immune responses by interleukin-12 in vitro.

J. Berzofsky, M. Clerici, T. Wynn, 1993, Science.

A TH1-->TH2 switch is a critical step in the etiology of HIV infection.

M. Clerici, G. Shearer, 1993, Immunology today.

Type 1 and type 2 cytokine dysregulation in human infectious, neoplastic, and inflammatory diseases

M. Clerici, G. Shearer, Daniel Lucey, 1996, Clinical microbiology reviews.

HIV-1 from a seronegative transplant donor.

J. Berzofsky, M. Clerici, C. Tacket, 1992, The New England journal of medicine.

Is sperm immunosuppressive in male homosexuals and vasectomized men?

U. Hurtenbach, G. Shearer, 1982, Immunology today.

Germ cell-induced immune suppression in mice. Effect of inoculation of syngeneic spermatozoa on cell-mediated immune responses

U. Hurtenbach, G. Shearer, 1982, The Journal of experimental medicine.

Longitudinal study of in vitro CD4+ T helper cell function in recently transplanted renal allograft patients undergoing tapering of their immunosuppressive drugs.

M. Miller, R. Schulick, G. Shearer, 1993, Transplantation.

Epidermal Langerhans cells can function as stimulatory cells but not as accessory cells in CTL induction.

H. Pehamberger, M. Iijima, G. Shearer, 1984, Journal of immunology.

Xenogeneic serum-induced murine cytotoxic cells. I. The generation of effector components specific for self and allogeneic target cells.

G. Shearer, K. J. Kim, R. Levy, 1979, Cellular immunology.

A strategy for prophylactic vaccination against HIV.

M. Clerici, G. Shearer, J. Salk, 1993, Science.

Exposure to human immunodeficiency virus (HIV) type I indicated by HIV-specific T helper cell responses before detection of infection by polymerase chain reaction and serum antibodies [corrected].

J. Berzofsky, M. Clerici, C. Tacket, 1991, The Journal of infectious diseases.

The tumor enhancement phenomenon: reinterpretation from a Th1/Th2 perspective.

M. Clerici, G. Shearer, E. Clerici, 1996, Journal of the National Cancer Institute.

Cell Adhesiveness Is Related in Malignant Lymphoid Cells to Tumorigenicity

M. Gottesman, G. Shearer, J. Hochman, 2002 .

CELLULAR DIFFERENTIATION OF THE IMMUNE SYSTEM OF MICE

G. Shearer, G. Cudkowicz, 1969, The Journal of experimental medicine.

Augmentation of antitumor immune response by trinitrophenyl (TNP)-reactive helper T-cells: enhanced induction of tumor-specific Lyt-1+2- T-cell-mediated delayed-type hypersensitivity from spleen cells of tumor-bearing mice by TNP helpers.

H. Fujiwara, G. Shearer, T. Hamaoka, 1986, Journal of the National Cancer Institute.

Evidence for a similar or common mechanism for natural killer cell activity and resistance to hemopoietic grafts

G. Shearer, O. Haller, H. Wigzell, 1977, European journal of immunology.

CELLULAR DIFFERENTIATION OF THE IMMUNE SYSTEM OF MICE

G. Shearer, G. Cudkowicz, R. Priore, 1969, The Journal of experimental medicine.

CONTRIBUTION OF DIFFERENT CELL TYPES TO THE GENETIC CONTROL OF IMMUNE RESPONSES AS A FUNCTION OF THE CHEMICAL NATURE OF THE POLYMERIC SIDE CHAINS (POLY-L-PROLYL AND POLY-DL-ALANYL) OF SYNTHETIC IMMUNOGENS

M. Sela, E. Mozes, G. Shearer, 1972, The Journal of experimental medicine.

Protection against graft vs. host-associated immunosuppression in F1 mice. I. Activation of F1 regulatory cells by host-specific anti-major histocompatibility complex antibodies

D. Sachs, U. Hurtenbach, G. Shearer, 1981, The Journal of experimental medicine.

Functional and phenotypic alterations in T cell subsets during the course of MAIDS, a murine retrovirus-induced immunodeficiency syndrome.

M. Miller, R. Hardy, H. Morse, 1989, Journal of immunology.

A bicellular mechanism in the immune response to chemically defined antigens. 3. Interaction of thymus and bone marrow-derived cells.

A. Globerson, S. Segal, G. Shearer, 1971, Cellular immunology.

Graft-vs.-host-associated immune suppression is activated by recognition of allogeneic murine I-A antigens

G. Shearer, R. Levy, 1983, The Journal of experimental medicine.

Mutual recognition of parental and F1 lymphocytes. II. Analysis of graft-vs-host-induced suppressor cell activity for T cell-mediated lympholysis to trinitrophenyl self and alloantigens.

G. Shearer, R. Polisson, 1980, Journal of immunology.

Mutual recognition of parental and F1 lymphocytes. Selective abrogation of cytotoxic potential of F1 lymphocytes by parental lymphocytes

G. Shearer, R. Polisson, 1980, The Journal of experimental medicine.

CELLULAR DIFFERENTIATION OF THE IMMUNE SYSTEM OF MICE

G. Shearer, G. Cudkowicz, R. Priore, 1968, The Journal of experimental medicine.

Oligocellular mechanism in the production of antibodies: in vitro response to a haptenic determinant.

A. Globerson, G. Shearer, M. Feldman, 1973, Cellular immunology.

Cooperation of antigenic determinants in intact mice and interference by antigenic competition

M. Taussig, M. Sela, E. Mozes, 1972, European journal of immunology.

CELLULAR DIFFERENTIATION OF THE IMMUNE SYSTEM OF MICE

T. Ito, G. Shearer, G. Cudkowicz, 1969, The Journal of experimental medicine.

DISTINCT EVENTS IN THE IMMUNE RESPONSE ELICITED BY TRANSFERRED MARROW AND THYMUS CELLS

G. Shearer, G. Cudkowicz, 1969, The Journal of experimental medicine.

Cell Interactions in the In Vitro Production of Antibodies to Chemically Defined Antigens

A. Globerson, S. Segal, G. Shearer, 1971 .

Incorporation of zidovudine into leukocyte DNA from HIV-1-positive adults and pregnant women, and cord blood from infants exposed in utero.

R. Tarone, H. Kessler, C. Chougnet, 1999, AIDS.

Lamivudine in children with human immunodeficiency virus infection: a phase I/II study. The National Cancer Institute Pediatric Branch-Human Immunodeficiency Virus Working Group.

J. Church, D. Venzon, F. Balis, 1996, The Journal of infectious diseases.

Altered immunoregulation and autoimmune aspects of HIV infection: relevant murine models.

H. Morse, G. Shearer, C. Via, 1990, Immunology today.

Cell-mediated immune response to human immunodeficiency virus (HIV) type 1 in seronegative homosexual men with recent sexual exposure to HIV-1.

J. Berzofsky, M. Clerici, J. Giorgi, 1992, The Journal of infectious diseases.

Receptors for Low-Molecular-Weight Hormones on Lymphocytes

H. Bourne, P. Insel, K. Melmon, 1977 .

T-helper cell responses to HIV envelope peptides in cord blood: protection against intrapartum and breast-feeding transmission

M. Clerici, N. Mngqundaniso, H. Coovadia, 2001, AIDS.

HIV‐1‐specific cellular immune responses among HIV‐1‐resistant sex workers

R. Kaul, N. Nagelkerke, F. Plummer, 2000, Immunology and cell biology.

Cellular immune factors associated with mother‐to-infant transmission of HIV

J. Berzofsky, D. Venzon, M. Clerici, 1993, AIDS.

Pluripotent Stem Cell Function of the Mouse Marrow "Lymphocyte"

G. Shearer, G. Cudkowicz, M. Bennett, 1964, Science.

Chronic innate immune activation as a cause of HIV-1 immunopathogenesis.

A. Boasso, G. Shearer, 2008, Clinical immunology.

An epitope in human immunodeficiency virus 1 reverse transcriptase recognized by both mouse and human cytotoxic T lymphocytes.

J. Berzofsky, B. Moss, R. Germain, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Alloantigenic stimulation bypasses CD28‐B7 costimulatory blockade by an interleukin‐2‐dependent mechanism

G. Shearer, L. Pinto, C. M. Trubey, 2000, Journal of leukocyte biology.

ENV-specific cytotoxic T lymphocyte responses in HIV seronegative health care workers occupationally exposed to HIV-contaminated body fluids.

J. Berzofsky, M. Clerici, H. Kessler, 1995, The Journal of clinical investigation.

Apoptotic cell death and cytokine dysregulation in human immunodeficiency virus infection: pivotal factors in disease progression

M. Clerici, P. Henkart, A. Sarin, 1997, Cell Death and Differentiation.

Recombinant Vaccine-Induced Protection against the Highly Pathogenic Simian Immunodeficiency Virus SIVmac251: Dependence on Route of Challenge Exposure

E. Paoletti, D. Montefiori, D. Venzon, 1998, Journal of Virology.

Therapies du vih-1 basees sur l'engiogenine

G. Shearer, M. Rugeles, J. Oppenheim, 2004 .

Monocyte-Derived Dendritic Cells from Normal Immune Function of

Sandra Cohen, Gene M. Shearer, Alan L. Landay, 2012 .

Evidence for a new segregant series of B cell antigens that are encoded in the HLA-D region and that stimulate secondary allogenic proliferative and cytotoxic responses

G. Shearer, S. Shaw, A. Johnson, 1980, The Journal of experimental medicine.

Early T-helper cell defects in HIV infection.

M. Clerici, G. Shearer, 1991, AIDS.

Immune dysregulation in human immunodeficiency virus infection: know it, fix it, prevent it?

C. Chougnet, A. Boasso, G. Shearer, 2009, Journal of internal medicine.

Highly effective treatment of acquired immunodeficiency syndrome-related lymphoma with dose-adjusted EPOCH: impact of antiretroviral therapy suspension and tumor biology.

W. Wilson, S. Steinberg, E. Jaffe, 2003, Blood.

H-2-linked genetic control of murine T-cell-mediated lympholysis to autologous cells modified with low concentrations of trinitrobenzene sulfonate

C. Pettinelli, M. Miller, G. Shearer, 1979, The Journal of experimental medicine.

Construction of peptides encompassing multideterminant clusters of human immunodeficiency virus envelope to induce in vitro T cell responses in mice and humans of multiple MHC types.

J. Berzofsky, M. Clerici, G. Shearer, 1991, The Journal of clinical investigation.

T Helper Cell Responses

J. Berzofsky, M. Clerici, G. Shearer, 1990 .

Genetic control of the immune response to staphylococcal nuclease. IV. H-2-linked control of the relative proportions of antibodies produced to different determinants of native nuclease

A. Schechter, J. Berzofsky, D. Sachs, 1977, The Journal of experimental medicine.

Human glioma-induced immunosuppression involves soluble factor(s) that alters monocyte cytokine profile and surface markers.

J. Coligan, T. Roszman, J. Shuman, 1999, Journal of immunology.

CTLA-4 blockade decreases TGF-beta, IDO, and viral RNA expression in tissues of SIVmac251-infected macaques.

D. Fuchs, M. Betts, D. Venzon, 2006, Blood.

Differential lack of class I H-2d antigen expression by sublines of the BALB/c S49 T cell lymphoma.

K. Ozato, G. Shearer, J. Hochman, 1986, Journal of immunology.

Brief Definitive Report Correlation of Suppressor Cell Development in Parental and F~ Hybrid Mouse Strains with the Growth of a Parental Tumor in Vivo

G. Shearer, R. Levy, S. Waksal, 2022 .

In vitro correction of antigen-induced immune suppression: effects of poly(A) poly(U) and prostaglandin E.

H. Bourne, K. Melmon, E. Mozes, 1973, Cellular immunology.

Human cellular immune response to Giardia lamblia

G. Shearer, T. Nash, B. Gottstein, 1991, Infection.

Experimental allergic orchitis in mice

K. Tung, C. Teuscher, G. Shearer, 1985, Immunogenetics.

GENETIC CONTROL OF THE IMMUNE RESPONSE TO STAPHYLOCOCCAL NUCLEASE

D. Sachs, G. Shearer, E. Lozner, 1974, Springer Seminars in Immunopathology.

Studies on in vivo priming to TNP-reactive cytotoxic effector cell system. II. Augmented secondary cytotoxic response by radioresistant T cells and demonstration of differential helper activity as a function of the stimulating dose of TNP-self.

G. Shearer, H. Fujiwara, 1980, Journal of immunology.

Studies on in vivo priming of the TNP-reactive cytotoxic effector cell system. I. Comparison of the effects of intravenous inoculation with TNP-conjugated cells on the development of contact sensitivity and cell-mediated lympholysis.

G. Shearer, R. Levy, W. Terry, 1979, Journal of immunology.

Enhanced TNP-reactive helper T cell activity and its utilization in the induction of amplified tumor immunity that results in tumor regression.

H. Fujiwara, G. Shearer, T. Hamaoka, 1984, Journal of immunology.

Effects of sodium periodate modification of lymphocytes on the sensitization and lytic phases of T cell-mediated lympholysis.

G. Shearer, A. Schmitt-Verhulst, 1976, Journal of immunology.

Helper cell analysis in cytotoxic T lymphocyte responses I. Activation of specific and cross‐reactive helper effects in two hapten‐modified self responses

H. Fujiwara, G. Shearer, R. Levy, 1980, European journal of immunology.

Cross-reactive recognition of alloantigens and certain B6 mutant antigens by antigen-specific and polyclonally activated cytotoxic effector cells.

U. Hurtenbach, G. Shearer, R. Levy, 1983, Cellular immunology.

Studies on in-vivo priming of the trinitrophenyl-reactive cytotoxic effector-system. III. Are helper T cells involved in the in-vitro generation of cross-reactive as well as restricted cytotoxic responses?

G. Shearer, R. Levy, H. Fujiwara, 1982, Immunobiology.

Suppressive effect of X-irradiated tumor cell presensitization on the induction of syngeneic tumor immunity. II. Opposite effects of intravenous administration of TNP-conjugated tumor cells on the development of antitumor and anti-TNP-self cytotoxic effector cells.

G. Shearer, H. Fujiwara, 1981, Cellular immunology.

Non‐H‐2‐associated genetic regulation of cytotoxic responses to hapten‐modified syngeneic cells Effect on the magnitude of secondary response and helper T cell generation after in vivo priming

H. Fujiwara, G. Shearer, 1981, European journal of immunology.

H-2 homology requirements for secondary cell-mediated lympholysis and miced lymphocyte reactions to TNP-modified syngeneic lymphocytes.

G. Shearer, C. Garbarino, A. Schmitt-Verhulst, 1977, Journal of immunology.

Role of self and foreign antigenic determinants in allogeneic and self- restricted cytotoxic T cell recognition

G. Shearer, R. Levy, P. Gilheany, 1980, The Journal of experimental medicine.

Regulation of T-cell-mediated lympholysis by the murine major histocompatibility complex. I. Preferential in vitro responses to trinitrophenyl-modified self K- and D-coded gene products in parental and F1 hybrid mouse strains

G. Shearer, R. Levy, 1979, The Journal of experimental medicine.

H-2-linked genetic control of murine cell-mediated lympholysis to autologous cells modified with high and low concentrations of fluorescein isothiocyanate.

G. Shearer, R. Levy, P. K. Arora, 1981, Cellular immunology.

Enhancement of immune response potential of mouse lymphoid cells fractionated over insolubilized conjugated histamine columns.

K. Melmon, G. Shearer, Y. Weinstein, 1974, Journal of immunology.

Bifunctional major histocompatibility-linked genetic regulation of cell- mediated lympholysis to trinitrophenyl-modified autologous lymphocytes

G. Shearer, A. Schmitt-Verhulst, 1975, The Journal of experimental medicine.

Cell-mediated lympholysis of trinitrophenyl-modified autologous lymphocytes. Confirmation of genetic control of response to trinitrophenyl-modified H-2 antigens by the use of anti-H-2 and anti-Ia antibodies

D. Sachs, G. Shearer, A. Schmitt-Verhulst, 1976, The Journal of experimental medicine.

Animal Models of Acute and Chronic Graft‐Versus‐Host Disease

G. Shearer, R. Gress, F. Hakim, 1998, Current protocols in immunology.

Progression from Acute to Chronic Disease in a Murine Parent-into-F1 Model of Graft-Versus-Host Disease

E. Mozes, G. Shearer, J. Tschetter, 2000, The Journal of Immunology.

Graft-Versus-Host Disease Model of 1 a Murine Parent-into-F Progression from Acute to Chronic Disease in

E. Mozes, G. Shearer, J. Tschetter, 2000 .

Regulation of T-cell-mediated lympholysis by the murine major histocompatibility complex. II. Control of cytotoxic responses to trinitrophenyl-K and -D self products by H-2K- and H-2D-Region genes

G. Shearer, R. Levy, 1980, The Journal of experimental medicine.

HIV-1-driven regulatory T-cell accumulation in lymphoid tissues is associated with disease progression in HIV/AIDS.

C. Chougnet, J. Andersson, M. Vaccari, 2006, Blood.

Immune Activation Driven by CTLA-4 Blockade Augments Viral Replication at Mucosal Sites in Simian Immunodeficiency Virus Infection1

D. Fuchs, R. Koup, D. Venzon, 2008, The Journal of Immunology.

Cutting Edge: The Prevalence of Regulatory T Cells in Lymphoid Tissue Is Correlated with Viral Load in HIV-Infected Patients 1

N. Shire, C. Chougnet, J. Andersson, 2005, The Journal of Immunology.

T helper cell immune dysfunction in asymptomatic, HIV-1-seropositive individuals: the role of TH1-TH2 cross-regulation.

M. Clerici, G. Shearer, 1992, Chemical immunology.

Multiple patterns of alloantigen presenting/stimulating cell dysfunction in patients with AIDS.

M. Clerici, H. Kessler, G. Shearer, 1991, Journal of immunology.

Regulation of TNF-related apoptosis-inducing ligand on primary CD4+ T cells by HIV-1: role of type I IFN-producing plasmacytoid dendritic cells.

A. Boasso, J. Herbeuval, Andrew W. Hardy, 2005, Proceedings of the National Academy of Sciences of the United States of America.

HIV Type 1 Resistance in Kenyan Sex Workers Is Not Associated with Altered Cellular Susceptibility to HIV Type 1 Infection or Enhanced β-Chemokine Production

S. Rowland-Jones, F. Plummer, J. Kimani, 1998 .

Immune response to human immunodeficiency virus (HIV) in healthcare workers occupationally exposed to HIV-contaminated blood.

J. Berzofsky, H. Kessler, G. Shearer, 1997, The American journal of medicine.

CD40 ligand and IFN‐γ synergistically restore IL‐12 production in HIV‐infected patients

S. Buchbinder, H. Kessler, C. Chougnet, 1998 .

Unique T-cell immune abnormalities in the development of acquired immune deficiency syndrome (AIDS).

G. Shearer, D. Bernstein, 1986, Cancer investigation.

Modulation of T cell responses to recall antigens presented by Langerhans cells in HIV-discordant identical twins by anti-interleukin (IL)-10 antibodies and IL-12.

C. Chougnet, A. Blauvelt, G. Shearer, 1996, The Journal of clinical investigation.

Interleukin-2 production used to detect antigenic peptide recognition by T-helper lymphocytes from asymptomatic HIV-seropositive individuals

J. Berzofsky, M. Clerici, D. Mann, 1989, Nature.

Functional studies of epidermal Langerhans cells and blood monocytes in HIV-infected persons.

S. Steinberg, M. Clerici, A. Blauvelt, 1995, Journal of immunology.

Detection of cytotoxic T lymphocytes specific for synthetic peptides of gp160 in HIV-seropositive individuals.

J. Berzofsky, M. Clerici, G. Shearer, 1991, Journal of immunology.

Elevated allogeneic cytotoxic T lymphocyte activity in peripheral blood leukocytes of homosexual men.

K. Tung, G. Shearer, F. Koster, 1985, Journal of immunology.

Cell types required for H-2-restricted cytotoxic responses generated by trinitrobenzene sulfonate-modified syngeneic cells or trinitrophenyl-conjugated proteins.

C. Pettinelli, G. Shearer, A. Schmitt-Verhulst, 1979, Journal of immunology.

Transient increase of interferon-stimulated genes and no clinical benefit by chloroquine treatment during acute simian immunodeficiency virus infection of macaques.

A. Hryniewicz, M. Vaccari, A. Boasso, 2014, AIDS research and human retroviruses.

Defective maternal-fetal interaction in a murine autoimmune model.

B. Tartakovsky, E. Mozes, G. Shearer, 1996, Human reproduction.

The tolerogenic peptide hCDR1 immunomodulates cytokine and regulatory molecule gene expression in blood mononuclear cells of primary Sjogren's syndrome patients.

A. Sharabi, H. Zinger, E. Mozes, 2018, Clinical immunology.

NONINFECTIOUS COFACTORS IN SUSCEPTIBILITY TO AIDS: POSSIBLE CONTRIBUTIONS OF SEMEN, HLA ALLOANTIGENS, AND LACK OF NATURAL RESISTANCE

G. Shearer, R. Levy, 1984, Annals of the New York Academy of Sciences.

B7-H1 is up-regulated in HIV infection and is a novel surrogate marker of disease progression.

R. Maserati, Lieping Chen, M. Clerici, 2003, Blood.

Immune-deficiency syndrome (AIDS) A consequence of allogeneic Ia-antigen recognition.

G. Shearer, 1983, Immunology today.

HIV-specific immunity following immunization with HIV synthetic envelope peptides in asymptomatic HIV-infected patients.

S. Steinberg, J. Berzofsky, G. Shearer, 1999, AIDS.

Role of interleukin-10 in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus.

J. Berzofsky, A. Sher, M. Clerici, 1994, The Journal of clinical investigation.

The role of thymus cells in the immune response to poly(Tyr, Glu)‐polyD L Ala–polyLys as a function of the genetic constitution of the mouse strain

M. Sela, E. Mozes, G. Shearer, 1974, European journal of immunology.

Cellular studies of the genetic control of immune response toward the loop region of lysozyme.

M. Sela, E. Mozes, G. Shearer, 1973, Journal of immunology.

CONTRIBUTION OF BONE MARROW CELLS AND LACK OF EXPRESSION OF THYMOCYTES IN GENETIC CONTROLS OF IMMUNE RESPONSES FOR TWO IMMUNOPOTENT REGIONS WITHIN POLY-(PHE,GLU)-POLY-PRO--POLY-LYS IN INBRED MOUSE STRAINS

E. Mozes, G. Shearer, 1971, The Journal of experimental medicine.

PDL-1 upregulation on monocytes and T cells by HIV via type I interferon: restricted expression of type I interferon receptor by CCR5-expressing leukocytes.

M. Clerici, A. Boasso, Andrew W. Hardy, 2008, Clinical immunology.

Immunological unresponsiveness induced in adult mice to synthetic polypeptides built on multichain polyproline and multichain polyalanine.

M. Sela, E. Mozes, B. Bonavida, 1974, Immunochemistry.

Cellular analysis of the phenotypic correction of the genetically controlled low immune response to the polyproline determinant by macrophages.

M. Sela, E. Mozes, G. Shearer, 1974, Cellular immunology.

Effect of Aging on Cytokine Production in Normal and Experimental Systemic Lupus Erythematosus-Afflicted Mice

A. Globerson, E. Mozes, G. Shearer, 2000, Experimental Gerontology.

Influence of human immunodeficiency virus-infected maternal environment on development of infant interleukin-12 production.

S. Steinberg, C. Chougnet, D. Liewehr, 2000, The Journal of infectious diseases.

Human cytotoxic response in vitro to trinitrophenyl-modified autologous cells. I. T cell recognition of TNP in association with widely shared antigens.

G. Shearer, D. Nelson, S. Shaw, 1978, Journal of immunology.

CELLULAR DIFFERENTIATION OF THE IMMUNE SYSTEM OF MICE

G. Shearer, G. Cudkowicz, R. Priore, 1969, The Journal of experimental medicine.

Value of in vitro CD4+ T helper cell function test for predicting long-term loss of human renal allografts.

M. Clerici, R. Schulick, G. Shearer, 1994, Transplantation.

Correlation of in vitro CD4+ T helper cell function with clinical graft status in immunosuppressed kidney transplant recipients.

P. Kimmel, M. Clerici, G. Shearer, 1991, Transplantation.

AUGMENTATION OF GRAFT‐VERSUS‐HOST REACTION BY CYTOMEGALOVIRUS INFECTION RESULTING IN INTERSTITIAL PNEUMONITIS

J. Shanley, G. Shearer, J. Grundy, 1985, Transplantation.

AIDS as a consequence of la antigen recognition: a closer look.

M. Moser, G. Shearer, 1986, Immunology today.

Mutual recognition of parental and F lymphocytes. III. Parental determinants recognized by F host mice in resistance to graft-vs-host-associated immunosuppression map to H-2Db.

G. Shearer, R. Polisson, 1981, Journal of immunology.

Negative correlation between blood cell counts and serum neopterin concentration in patients with HIV-1 infection.

E. Werner, D. Fuchs, M. Clerici, 1991, AIDS.

Induction of F1 hybrid antiparent cytotoxic effector cells: an in vitro model for hemopoietic histoincompatibility

G. Shearer, G. Cudkowicz, 1975, Science.

RECOGNITION OF CHEMICALLY MODIFIED AUTOLOGOUS CELLS: IMPORTANCE OF THE MURINE MAJOR HISTOCOMPATIBILITY COMPLEX

G. Shearer, 1975 .

Blood transfusion and susceptibility to AIDS.

G. Shearer, R. Levy, 1984, The New England journal of medicine.

In Vivo CD40-CD154 (CD40 Ligand) Interaction Induces Integrated HIV Expression by APC in an HIV-1-Transgenic Mouse Model1

A. Sher, C. Chougnet, M. Schito, 2001, The Journal of Immunology.

Mouse Model Expression by APC in an HIV-1-Transgenic Interaction Induces Integrated HIV In Vivo CD 40-CD 154 ( CD 40 Ligand )

A. Sher, C. Chougnet, M. Schito, 2001 .

Genetic control of the murine cell-mediated immune response in vivo. II. H-2 linked responsiveness to the synthetic polypeptide poly(Tyr,Glu)-poly(DL-Ala)--poly(Lys).

M. Sela, E. Mozes, G. Shearer, 1975, Journal of immunology.

GENETIC CONTROL OF NATURAL RESISTANCE TO GRAFT VERSUS HOST-ASSOCIATED SUPPRESSION OF T CELL-MEDIATED LYMPHOLYSIS

Matthew W. Miller, G. Shearer, R. Polisson, 1980 .

Natural Resistance to Parental T‐Lymphocyte‐Induced Immunosuppression in F1 Hybrid Mice: Implications for Acquired Immune Deficiency Syndrome (AIDS)

G. Shearer, 1983, Immunological reviews.

Properties of H-2L locus products in allogeneic and H-2 restricted, trinitrophenyl-specific cytotoxic responses.

G. Shearer, R. Levy, T. Hansen, 1978, Journal of immunology.

Analysis of murine T lymphocyte markers during the early phases of GvH-associated suppression of cytotoxic T lymphocyte responses.

U. Hurtenbach, G. Shearer, 1983, Journal of immunology.

F1 hybrid antiparental cell-mediated lympholysis: a comparison with bone marrow graft rejection and with cell-mediated lympholysis to alloantigens.

G. Shearer, P. Evans, G. Cudkowicz, 1977, Cold Spring Harbor symposia on quantitative biology.

In vitro induction of F1 hybrid anti-parent cell-mediated cytotoxicity.

G. Shearer, G. Cudkowicz, C. Garbarino, 1976, Journal of immunology.

HIV-specific T-helper activity in seronegative health care workers exposed to contaminated blood.

J. Berzofsky, M. Clerici, H. Kessler, 1994, JAMA.

MODULATION OF T CELL DIFFERENTIATION, ANTIGEN EXPRESSION, AND RADIOSENSITIVITY OF SUPPRESSOR CELLS DURING LATE PHASES OF GRAFT‐VERSUS‐HOST REACTIVITY

U. Hurtenbach, G. Shearer, T. Tsuchida, 1984, Transplantation.

T‐cell proliferation to subinfectious SIV correlates with lack of infection after challenge of macaques

M. Clerici, E. Clark, G. Shearer, 1994, AIDS.

Replication of simian immunodeficiency virus (SIV) in ex vivo lymph nodes as a means to assess susceptibility of macaques in vivo.

C. Chougnet, M. Robert-Guroff, L. Margolis, 2000, Virology.

The Relationships Between Cytokines, Complement and HIV Infection

M. Clerici, G. Shearer, A. Clivio, 1999 .

Molecular analysis of decreased interleukin-12 production in persons infected with human immunodeficiency virus.

A. Sher, M. Clerici, H. Kessler, 1996, The Journal of infectious diseases.

Discordant cellular and humoral immune responses to cytomegalovirus infection in healthy blood donors: existence of a Th1-type dominant response.

F. Marincola, S. Epstein, G. Shearer, 2001, International immunology.

Human immunodeficiency virus reverse transcriptase T helper epitopes identified in mice and humans: correlation with a cytotoxic T cell epitope.

J. Berzofsky, R. Houghten, M. Clerici, 1991, The Journal of infectious diseases.

Immune-based approaches for control of HIV infection and viral-induced immunopathogenesis.

G. Shearer, L. Pinto, V. Blazevic, 2000, Clinical immunology.

HIV-1 infection induces a selective reduction in STAT5 protein expression.

M. Dolan, G. Shearer, R. Kirken, 1998, Journal of immunology.

Interleukin-15 but Not Interleukin-7 Abrogates Vaccine-Induced Decrease in Virus Level in Simian Immunodeficiency Virusmac251-Infected Macaques1

R. Koup, D. Douek, D. Venzon, 2007, The Journal of Immunology.

Cytokine dysregulation in invasive cervical carcinoma and other human neoplasias: time to consider the TH1/TH2 paradigm.

M. Clerici, G. Shearer, E. Clerici, 1998, Journal of the National Cancer Institute.

Combined Effect of Antiretroviral Therapy and Blockade of IDO in SIV-Infected Rhesus Macaques1

D. Fuchs, M. Vaccari, A. Boasso, 2009, The Journal of Immunology.

Mucosal Sites in Simian Immunodeficiency Blockade Augments Viral Replication at Immune Activation Driven by CTLA-4

R. Koup, D. Venzon, J. Héraud, 2008 .

T cell responses to recall antigens, alloantigen, and mitogen of HIV-infected patients receiving long-term combined antiretroviral therapy.

H. Kessler, G. Shearer, A. Landay, 2000, AIDS research and human retroviruses.

Cytotoxic T lymphocyte responses against alloantigens exhibit preferential effector cell activity for H-2K or H-2D region products similar to that for H-2 restricted responses.

G. Shearer, R. Levy, C. Lucas, 1981, Journal of immunology.

Importance of CD8+ T helper cell function in AIDS.

A. Singer, H. Morse, G. Shearer, 1988, Journal of Infectious Diseases.

T cell-antigen-presenting cell interactions in human systemic lupus erythematosus. Evidence for heterogeneous expression of multiple defects.

M. Clerici, G. Tsokos, G. Shearer, 1993, Journal of immunology.

Alloactivated cytotoxic T cells recognize the carboxy‐terminal domain of human immunodeficiency virus‐1 gp120 envelope glycoprotein

A. Dalgleish, G. Shearer, B. Jameson, 1993, European journal of immunology.

Loss of proliferative capacity and T cell immune development potential by bone marrow from mice undergoing a graft-vs-host reaction.

G. Shearer, T. Iwasaki, H. Fujiwara, 1986, Journal of immunology.

Prospective study of cytotoxic T lymphocyte responses to influenza and antibodies to human T lymphotropic virus-III in homosexual men. Selective loss of an influenza-specific, human leukocyte antigen-restricted cytotoxic T lymphocyte response in human T lymphotropic virus-III positive individuals wi

R. Gallo, G. Shearer, W. Biddison, 1985, The Journal of clinical investigation.

Human cytotoxic T cell responses to trinitrophenyl hapten and influenza virus. Diversity of restriction antigens and specificity of HLA-linked genetic regulation.

G. Shearer, W. Biddison, S. Shaw, 1980, The Journal of experimental medicine.

Attenuation of Pathogenic Immune Responses during Infection with Human and Simian Immunodeficiency Virus (HIV/SIV) by the Tetracycline Derivative Minocycline

Julia L. Drewes, M. Zink, D. Graham, 2014, PloS one.

Effect of graft-versus-host reaction on thymic function

M. Fukuzawa, G. Shearer, 1988, Immunologic research.

Interleukin 2 receptor dysfunction in mice undergoing a graft-vs-host reaction.

T. Malek, G. Shearer, T. Iwasaki, 1985, Journal of immunology.

Correlates of protection in HIV infection and the progression of HIV infection to AIDS.

M. Clerici, G. Shearer, 1996, Immunology letters.

Human cytotoxic response in vitro to trinitrophenyl-modified autologous cells. II. Diversity of self determinants recognized in association with TNP.

G. Shearer, S. Shaw, 1978, Journal of immunology.

HAART reduces death ligand but not death receptors in lymphoid tissue of HIV-infected patients and simian immunodeficiency virus-infected macaques

J. Andersson, M. Vaccari, A. Boasso, 2009, AIDS.

Highly Active Antiretroviral Therapy in Human Immunodeficiency Virus Type 1-Infected Children: Analysis of Cellular Immune Responses

S. Steinberg, G. Shearer, R. Yarchoan, 2001, Clinical Diagnostic Laboratory Immunology.

Protease inhibitor and triple‐drug therapy: cellular immune parameters are not restored in pediatric AIDS patients after 6 months of treatment

S. Steinberg, C. Chougnet, G. Shearer, 1998, AIDS.

Differential effect of type I and type II interferons on neopterin production and amino acid metabolism in human astrocyte-derived cells

D. Fuchs, A. Boasso, G. Shearer, 2008, Neuroscience Letters.

HIV-induced immunopathogenesis.

G. Shearer, Gene M. Shearer, 1998, Immunity.

Type 1 cytokine production and low prevalence of viral isolation correlate with long-term nonprogression in HIV infection.

M. Moroni, M. Clerici, G. Shearer, 1996, AIDS research and human retroviruses.

Depressive effect of silica particles on F1 hybrid anti-parent cell-mediated lympholysis induced in vitro.

G. Shearer, G. Cudkowicz, H. Waksal, 1978, Cellular immunology.

Antigenic peptides recognized by T lymphocytes from AIDS viral envelope-immune humans

K. Cease, J. Berzofsky, R. Cheynier, 1988, Nature.

Effect of Zidovudine Postexposure Prophylaxis on the Development of HIV-Specific Cytotoxic T-Lymphocyte Responses in HIV-Exposed Healthcare Workers

J. Berzofsky, M. Clerici, H. Kessler, 1999, Infection Control & Hospital Epidemiology.

Role of L3T4+ and Lyt-2+ donor cells in graft-versus-host immune deficiency induced across a class I, class II, or whole H-2 difference.

M. Moser, G. Shearer, S. Sharrow, 1988, Journal of immunology.

Failure of bone marrow cells to reconstitute T cell immunity in graft-vs-host mice.

M. Miller, G. Shearer, P. Lang, 1985, Journal of Immunology.

Genetic control of cell-mediated lympholysis to trinitrophenyl (TNP)-modified murine syngeneic cells. I. Expression of Ir gene function at the Cytotoxic precursor and helper cell levels in the response to TNP-H-2 b self.

G. Shearer, H. Fujiwara, 1981, Journal of immunology.

Genetic control of cell-mediated lympholysis to trinitrophenyl (TNP)-modified murine syngeneic cells. Expression of Ir gene function at the cytotoxic precursor and helper cell

G. Shearer, H. Fujiwara, 1981 .

Genetic control of the immune response to staphylococcal nuclease. III. Time-course and correlation between the response to native nuclease and the response to its polypeptide fragments

A. Schechter, J. Berzofsky, D. Sachs, 1977, The Journal of experimental medicine.

Synergy between subpopulations of normal mouse spleen cells in the in vitro generation of cell-mediated cytotoxicity specific for "modified self" antigens.

R. Hodes, K. Hathcock, G. Shearer, 1975, Journal of immunology.

Differential sensitivity of human T helper cell pathways by in vitro exposure to cyclosporin A.

M. Clerici, G. Shearer, 1990, Journal of immunology.

Reconstitution of long-term T helper cell function after zidovudine therapy in human immunodeficiency virus-infected patients.

J. Phair, D. Venzon, M. Clerici, 1992, The Journal of infectious diseases.

Allogeneic leukocytes as a possible factor in induction of aids in homosexual men.

G. Shearer, 1983, The New England journal of medicine.

Disease Progression B7-H1 is Upregulated in HIV infection and is a Novel Surrogate Marker of

R. Maserati, Lieping Chen, M. Clerici, 2013 .

Effect of cyclosporin A on lymphopoiesis. I. Absence of mature T cells in thymus and periphery of bone marrow transplanted mice treated with cyclosporin A.

G. Shearer, S. Sharrow, A. Kosugi, 1989, Journal of immunology.

Non-H-2-linked genetic control of murine cell-mediated lympholysis to autologous cells modified with fluorescein isothiocyanate (FTC-self).

G. Shearer, P. K. Arora, 1982, Journal of immunology.

IL-12 as Well as IL-2 Upregulates CCR5 Expression on T Cell Receptor-Triggered Human CD4+ and CD8+ T Cells

H. Fujiwara, G. Shearer, P. Gao, 2001, Journal of Clinical Immunology.

Interferon-Gamma and Interleukin-10 Production Among HIV-1–Infected and Uninfected Infants of HIV-1–Infected Mothers

M. Clerici, N. Mngqundaniso, H. Coovadia, 2001, Pediatric Research.

Incorporation of Zidovudine into Cord Blood DNA of Infants and Peripheral Blood DNA of Their HIV‐1‐Positive Mothers

C. Chougnet, G. Shearer, M. Poirier, 2000, Annals of the New York Academy of Sciences.

WR1065 mitigates AZT‐ddI‐induced mutagenesis and inhibits viral replication

J. Swenberg, Andrew W. Hardy, G. Shearer, 2009, Environmental and molecular mutagenesis.

Elevated Systemic Levels of Inflammatory Cytokines in Older Women with Persistent Cervical Human Papillomavirus Infection

R. Burk, A. Hildesheim, A. Rodriguez, 2010, Cancer Epidemiology, Biomarkers & Prevention.

ated Systemic Levels of Inflammatory Cytokines in Older men with Persistent Cervical Human B & P illomavirus Infection

R. Burk, A. Hildesheim, M. Schiffman, 2010 .

Thymus-independence of slowly metabolized immunogens.

M. Sela, E. Mozes, G. Shearer, 1972, Proceedings of the National Academy of Sciences of the United States of America.

Long-term protease inhibitor-containing therapy results in limited improvement in T cell function but not restoration of interleukin-12 production in pediatric patients with AIDS.

S. Steinberg, C. Chougnet, D. Liewehr, 2001, The Journal of infectious diseases.

HIV inhibitory activity generated by antigen‐stimulated cord blood leukocytes

G. Shearer, L. Pinto, E. Grene, 2003, AIDS.

Alloantigen-induced anti-HIV activity occurs prior to reverse transcription and can be generated by leukocytes from HIV-infected individuals.

M. Dolan, G. Shearer, L. Pinto, 2000, Blood.

CD4+ T-cell loss and delayed expression of modulators of immune responses at mucosal sites of vaccinated macaques following SIVmac251 infection

D. Fuchs, D. Venzon, M. Vaccari, 2008, Mucosal Immunology.

Cluster formation in vitro by mouse spleen cells and sheep erythrocytes.

G. Shearer, G. Cudkowicz, 1968, Journal of immunology.

Hemolytic Plaque-Forming Cells and Antigen-Sensitive Units in Spleens of Germfree and Conventional Mice

G. Shearer, G. Cudkowicz, H. E. Walburg, 1969 .

Leukocyte Separation on the Basis of their Receptors for Biogenic Amines and Prostaglandins: Relation of the Receptor to Antibody Formation

H. Bourne, K. Melmon, G. Shearer, 1974 .

Suppression of Human Cytotoxic T Lymphocyte Responses by Adherent Peripheral Blood Leukocytes

G. Shearer, D. Bernstein, 1988, Annals of the New York Academy of Sciences.

Immunologic profile of highly exposed yet HIV type 1-seronegative men.

W. John Boscardin, M. Carrington, S. O’Brien, 2002, AIDS research and human retroviruses.

Synergistic effect of murine cytomegalovirus on the induction of acute graft-vs-host disease involving MHC class I differences only. Analysis of in vitro T cell function.

J. Shanley, G. Shearer, C. Via, 1990, Journal of immunology.

ALTERED THRESHOLD FOR THE INDUCTION OF GRAFT‐VERSUS‐HOST IMMUNODEFICIENCY FOLLOWING MURINE CYTOMEGALOVIRUS INFECTION HOST AND DONOR CONTRIBUTIONS

J. Shanley, G. Shearer, C. Via, 1988, Transplantation.

IMMUNOBIOLOGY: INTERSTITIAL PNEUMONITIS DURING MURINE CYTOMEGALOVIRUS INFECTION AND GRAFT‐VERSUS‐HOST REACTION CHARACTERIZATION OF BRONCHOALVEOLAR LAVAGE CELLS

J. Shanley, G. Shearer, S. Sharrow, 1987, Transplantation.

How human immunodeficiency virus ravages the immune system

M. Clerici, G. Shearer, 1992, Current Biology.

Interstitial pneumonitis during murine cytomegalovirus infection and graft-versus-host reaction: effect of ganciclovir therapy.

J. Shanley, G. Shearer, C. Pomeroy, 1988, The Journal of infectious diseases.

Factors Affecting the Expansion of the Stem Cell Pool in Transplanted Mouse Bone Marrow

G. Shearer, A. Upton, G. Cudkowicz, 1964, Nature.

Studies on the mechanism of antigenic competition: Analysis of competition between synthetic polypeptide antigens

M. Sela, E. Mozes, G. Shearer, 1972, European Journal of Immunology.

Immunogenetic analysis of an unusual HLA region recombination by intrafamilial MLR, PLT, and CMC.

G. Shearer, S. Shaw, G. O'Neill, 1979, Transplantation proceedings.

Cellular aspects of the inverse relationship between the net charge of immunogens of antibodies elicited.

M. Sela, E. Mozes, G. Shearer, 1970, Proceedings of the National Academy of Sciences of the United States of America.

Semi-allogeneic cell hybrids stimulate HIV-1 envelope-specific cytotoxic T lymphocytes

J. Berzofsky, G. Shearer, E. Grene, 2000, AIDS.

Antigen‐stimulated apoptotic T‐cell death in HIV infection is selective for CD4+T cells, modulated by cytokines and effected by lymphotoxin

J. Berzofsky, R. Coffman, M. Clerici, 1996, AIDS.

Are blockers of gp120/CD4 interaction effective inhibitors of HIV-1 immunopathogenesis?

J. Herbeuval, G. Shearer, 2006, AIDS reviews.

Defective thymic education of L3T4+ T helper cell function in graft-vs-host mice.

G. Shearer, C. Via, M. Fukuzawa, 1988, Journal of Immunology.

Reduced HIV‐stimulated T‐helper cell reactivity in cord blood with short‐course antiretroviral treatment for prevention of maternal–infant transmission

M. Clerici, L. Kuhn, G. Shearer, 2001, Clinical and experimental immunology.

The role of antigen-presenting cells in HIV pathogenesis

C. Chougnet, G. Shearer, A. Landay, 2002, Current infectious disease reports.

Effect of cyclosporin A on lymphopoiesis. II. Developmental defects of immature and mature thymocytes in fetal thymus organ cultures treated with cyclosporin A.

G. Shearer, A. Kruisbeek, S. Sharrow, 1989, Journal of immunology.

Mac-1-Positive Host Cell Population of Infectious Virus Selectively from a Induces the Expression Mycobacterium avium Infection of HIV-1 Transgenic Mice with

A. Sher, C. Chougnet, M. Schito, 1999 .

Potential clinical applications of interleukin‐12

C. Chougnet, G. Shearer, 1996, Current opinion in hematology.

Peptides containing multideterminant clusters of human immunodeficiency virus envelope induce murine and human T-cell responses in diverse histocompatibility types.

J. Berzofsky, M. Clerici, G. Shearer, 1991, Transactions of the Association of American Physicians.

HIV type 1 resistance in Kenyan sex workers is not associated with altered cellular susceptibility to HIV type 1 infection or enhanced beta-chemokine production.

S. Rowland-Jones, F. Plummer, J. Kimani, 1998, AIDS research and human retroviruses.

β‐chemokines inhibit activation‐induced death of lymphocytes from HIV‐infected individuals

M. Dolan, G. Shearer, L. Pinto, 2000 .

Effect of FK 506 on CD4+ and CD8+ T-cell function in vivo.

M. Fukuzawa, G. Shearer, A. Okada, 1991, Transplantation proceedings.

Attenuated Retrovirus Vaccines and AIDS

M. Clerici, G. Shearer, Daniel Lucey, 1995, Science.

Comparison of in vitro immunostimulatory potential of live and inactivated influenza viruses.

G. Shearer, C. M. Trubey, V. Blazevic, 2000, Human immunology.

Redirecting T-cell function

G. Shearer, 1995, Nature.

Resistance to HIV infection: the genes are only part of the solution.

M. Clerici, G. Shearer, A. Clivio, 1997, Trends in Microbiology.

Apoptotic T cell death in HIV/AIDS

M. Clerici, G. Shearer, 1997, Cell Death and Differentiation.

Circumvention of defective CD4 T helper cell function in HIV-infected individuals by stimulation with HLA alloantigens.

M. Clerici, G. Shearer, R. Boswell, 1990, Journal of immunology.

tissues of SIVmac251-infected macaques , IDO, and viral RNA expression in β CTLA-4 blockade decreases TGF-

D. Fuchs, M. Betts, J. Héraud, 2013 .

Control of immunity in parental and F1, hybrid mouse strains to a spontaneously arising parental tumor I. Correlation between in vitro and in vivo anti‐tumor reactivity in responsive and unresponsive animals

G. Shearer, R. Levy, S. Waksal, 1977, European journal of immunology.

Immune correlates of protection from HIV and AIDS - more answers but yet more questions.

J. Strominger, J. Heeney, G. Shearer, 1999, Immunology today.

UV light exposure and HIV replication.

M. Clerici, G. Shearer, 1992, Science.

CD40 ligand and IFN-gamma synergistically restore IL-12 production in HIV-infected patients.

S. Buchbinder, H. Kessler, C. Chougnet, 1998, European journal of immunology.

Cell‐mediated cytotoxicity to trinitrophenyl‐modified syngeneic lymphocytes

G. Shearer, G. Shearer, 1974, European journal of immunology.

Separation of Leukocytes by their Amine Receptors: Subsequent Immunologic Functions

H. Bourne, K. Melmon, G. Shearer, 1974 .

Immune dysregulation in human immunodeficiency virus infection: know it, fix it, prevent it?

C. Chougnet, A. Boasso, G. Shearer, 2009, Journal of internal medicine.

Recombinant Vaccine-Induced Protection against the Highly Pathogenic Simian Immunodeficiency Virus SIVmac251: Dependence on Route of Challenge Exposure

E. Paoletti, D. Montefiori, D. Venzon, 1998, Journal of Virology.

IMMUNOBIOLOGY: INTERSTITIAL PNEUMONITIS DURING MURINE CYTOMEGALOVIRUS INFECTION AND GRAFT‐VERSUS‐HOST REACTION CHARACTERIZATION OF BRONCHOALVEOLAR LAVAGE CELLS

J. Shanley, G. Shearer, S. Sharrow, 1987 .

Transcellular activation of the human immunodeficiency virus type 1 long terminal repeat in cocultured lymphocytes

C. V. Noesel, F. Miedema, K. Tung, 1992, Journal of virology.

THE ROLE OF THYMOCYTES AND BONE MARROW CELLS IN DEFINING THE RESPONSE TO THE DINITROPHENYL HAPTEN ATTACHED TO POSITIVELY AND NEGATIVELY CHARGED SYNTHETIC POLYPEPTIDE CARRIERS

M. Sela, E. Mozes, G. Shearer, 1973, The Journal of experimental medicine.

CELLULAR DIFFERENTIATION OF THE IMMUNE SYSTEM OF MICE

G. Shearer, G. Cudkowicz, R. Priore, 1969, The Journal of experimental medicine.

CELLULAR DIFFERENTIATION OF THE IMMUNE SYSTEM OF MICE

G. Shearer, G. Cudkowicz, R. Priore, 1968, The Journal of experimental medicine.

H-2 LINKED BIFUNCTIONAL GENETIC CONTROL OF CELL-MEDIATED LYMPHOLYSIS TO TNP-MODIFIED AUTOLOGOUS CELL SURFACES

G. Shearer, A. Schmitt-Verhulst, 1976 .

Expression of both I-A and I-E/C subregion antigens on accessory cells required for in vitro generation of cytotoxic T lymphocytes against alloantigens or TNBS-modified syngeneic cells.

C. Pettinelli, G. Shearer, G. B. Ahmann, 1980, Journal of immunology.

Alloantigen-based AIDS vaccine: revisiting a "rightfully" discarded promising strategy

A. Boasso, G. Shearer, 2011, F1000 medicine reports.

Genetic control of the immune response to staphylococcal nuclease. IV. H-2-linked control of the relative proportions of antibodies produced to different determinants of native nuclease

A. Schechter, J. Berzofsky, D. Sachs, 1977, The Journal of experimental medicine.