S. Cartlidge

发表

AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action in vivo, pharmacokinetic/pharmacodynamic relationship, and potential for combination in preclinical models

Paul D. Martin, Mark Cockerill, Paul D. Smith, 2007, Molecular Cancer Therapeutics.

Soluble, crosslinked N-(2-hydroxypropyl)methacrylamide copolymers as potential drug carriers. 3. Targeting by incorporation of galactosamine residues. Effect of route of administration

J. Kopeček, R. Duncan, S. Cartlidge, 1987 .

Soluble, crosslinked N-(2-hydroxypropyl)methacrylamide copolymers as potential drug carriers: Pinocytosis by rat visceral yolk sacs and rat intestine cultured in vitro. Effect of molecular weight on uptake and intracellular degradation

J. Kopeček, R. Duncan, S. Cartlidge, 1987 .

Soluble, crosslinked N-(2-hydroxypropyl)methacrylamide copolymers as potential drug carriers. 2. Effect of molecular weight on blood clearance and body distribution in the rat after intravenous administration. Distribution of unfractionated copolymer after intraperitoneal, subcutaneous or oral admin

J. Kopeček, R. Duncan, S. Cartlidge, 1987 .

Dual IGF-I/II-neutralizing antibody MEDI-573 potently inhibits IGF signaling and tumor growth.

M. Tabrizi, D. Blakey, S. Coats, 2011, Cancer research.

Structure of a specific peptide complex of the carboxy‐terminal SH2 domain from the p85 alpha subunit of phosphatidylinositol 3‐kinase.

A. Breeze, J. Smith, S. Cartlidge, 1996, The EMBO journal.

The angiogenic receptor KDR is widely distributed in human tissues and tumours and relocates intracellularly on phosphorylation. An immunohistochemical study

G. Pillai, F. Pezzella, H. Turley, 2003, Histopathology.

PINOCYTIC CAPTURE AND INTRACELLULAR DEGRADATION OF POLY N-(2-HYDROXYPROPYL)-METHACRYLAMIDE CHAINS CONNECTED BY OLIGOPEPTIDE SEQUENCES.

J. Kopeček, R. Duncan, S. Cartlidge, 1982 .

368 Demonstration of broad in vivo anti-tumor activity of ARRY-142886 (AZD-6244), a potent and selective MEK inhibitor

S. Cartlidge, R. Woessner, T. Klinowska, 2004 .

Substrate selection and processing in endocytosis.

T. Kooistra, R. Duncan, S. Cartlidge, 1984, Biochemical Society Transactions.

Dual IGF-I/II-neutralizing antibody MEDI-573 potently inhibits IGF signaling and tumor growth.

M. Tabrizi, D. Blakey, S. Coats, 2011, Cancer research.