C. Flamme

The discovery of the benzhydroxamate MEK inhibitors CI-1040 and PD 0325901.

A. Doherty, J. Warmus, A. Bridges, 2008, Bioorganic & medicinal chemistry letters.

Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition

J. Warmus, J. Sebolt-Leopold, Chunhong Yan, 2004, Nature Structural &Molecular Biology.

4-anilino-5-carboxamido-2-pyridone derivatives as noncompetitive inhibitors of mitogen-activated protein kinase kinase.

Daniel F Ortwine, J. A. Spicer, W. Denny, 2007, Journal of medicinal chemistry.

2-Alkylamino- and alkoxy-substituted 2-amino-1,3,4-oxadiazoles-O-Alkyl benzohydroxamate esters replacements retain the desired inhibition and selectivity against MEK (MAP ERK kinase).

J. Warmus, A. Bridges, W. Leopold, 2008, Bioorganic & medicinal chemistry letters.

Corrigendum: Structures of human MAP kinase kinase 1 (MEK1) and MEK2 describe novel noncompetitive kinase inhibition

J. Warmus, J. Sebolt-Leopold, Chunhong Yan, 2005, Nature Structural &Molecular Biology.

The discovery of the benzhydroxamate MEK inhibitors CI-1040 and PD 0325901.

J. Warmus, J. Sebolt-Leopold, A. Saltiel, 2008, Bioorganic & medicinal chemistry letters.