B. Pan

发表

MK-2206, an Allosteric Akt Inhibitor, Enhances Antitumor Efficacy by Standard Chemotherapeutic Agents or Molecular Targeted Drugs In vitro and In vivo

P. Majumder, Hiroshi Sootome, H. Hirai, 2010, Molecular Cancer Therapeutics.

The effect of acidic pH on the ATPase activity and troponin Ca2+ binding of rabbit skeletal myofilaments.

B. Pan, R. Solaro, E. Blanchard, 1984, The Journal of biological chemistry.

Down-regulated CUL 7 in gastric carcinoma ( GC ) correlates to GC histopathological features

B. Pan, Gang Zhao, Huiqing Zhang, 2017 .

Angiogenesis - Research Frontiers. A Basic Science Conference of the New York Academy of Medicine

L. Sepp-Lorenzino, B. Pan, 2000, Expert opinion on investigational drugs.

Discovery of novel triazolobenzazepinones as γ-secretase modulators with central Aβ42 lowering in rodents and rhesus monkeys.

C. Kenific, C. Moxham, B. Pan, 2015, Bioorganic & medicinal chemistry letters.

Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor

Irena Ivanovska, C. Chiu, I. Kariv, 2017, The Journal of Pharmacology and Experimental Therapeutics.

STimulator of INterferon Genes Agonism Accelerates Antitumor Activity in Poorly Immunogenic Tumors

J. Cumming, Sarah Javaid, A. Tse, 2021, Molecular Cancer Therapeutics.

Slowly exchanging calcium binding sites unique to cardiac/slow muscle troponin C.

B. Pan, R. Solaro, K. A. Palmiter, 1990, Journal of molecular and cellular cardiology.

Abstract #1751: MK-8033, a selective c-Met / Ron inhibitor, suppresses tumor cell growth in vitro and in vivo

P. Majumder, W. Lu, K. Kunii, 2009 .

Discovery of a 5H-benzo[4,5]cyclohepta[1,2-b]pyridin-5-one (MK-2461) inhibitor of c-Met kinase for the treatment of cancer.

K. Kunii, M. Altman, A. Szewczak, 2011, Journal of medicinal chemistry.

Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer.

Andrew M Haidle, Matthew L. Maddess, J. Cumming, 2022, Journal of medicinal chemistry.

A prophylactic effect of aluminium-based adjuvants against respiratory viruses via priming local innate immunity

Qinjian Zhao, Zizheng Zheng, N. Xia, 2022, Emerging microbes & infections.

Genetic and Pharmacological Inhibition of PDK1 in Cancer Cells

C. Paweletz, Youwei Yan, M. Wiznerowicz, 2010, The Journal of Biological Chemistry.

Deletion of the first 45 NH2-terminal residues of rabbit skeletal troponin T strengthens binding of troponin to immobilized tropomyosin.

A. M. Gordon, J. Potter, B. Pan, 1991, The Journal of biological chemistry.

A Direct Regulatory Role for Troponin T and a Dual Role for Troponin C in the Ca2+ Regulation of Muscle Contraction (*)

J. Potter, Jiaju Zhao, B. Pan, 1995, The Journal of Biological Chemistry.

Control and Modulation of Contractile Activity of Cardiac Myofilaments

B. Pan, R. Solaro, 1989 .

Isolation, expression, and mutation of a rabbit skeletal muscle cDNA clone for troponin I. The role of the NH2 terminus of fast skeletal muscle troponin I in its biological activity.

J. Potter, B. Pan, T. Miller, 1992, The Journal of biological chemistry.

Removal of tropomyosin overlap modifies cooperative binding of myosin S-1 to reconstituted thin filaments of rabbit striated muscle.

A. M. Gordon, B. Pan, A M Gordon, 1989, The Journal of biological chemistry.

Calcium-binding properties of troponin C in detergent-skinned heart muscle fibers.

B. Pan, R. Solaro, 1987, The Journal of biological chemistry.

Analysis of the activating mutations within the activation loop of leukemia targets Flt-3 and c-Kit based on protein homology modeling.

Laura Sepp-Lorenzino, L. Sepp-Lorenzino, B. Pan, 2004, Journal of molecular graphics & modelling.

FGFR2 Is Amplified in the NCI-H716 Colorectal Cancer Cell Line and Is Required for Growth and Survival

B. Pan, B. Lutterbach, Anjili Mathur, 2014, PloS one.

Lung cancer cell lines harboring MET gene amplification are dependent on Met for growth and survival.

N. Kohl, J. Gibbs, H. Hatch, 2007, Cancer research.

Met activation in non-small cell lung cancer is associated with de novo resistance to EGFR inhibitors and the development of brain metastasis.

M. Loda, J. Minna, L. Chirieac, 2010, The American journal of pathology.

MK-2461, a novel multitargeted kinase inhibitor, preferentially inhibits the activated c-Met receptor.

C. Paweletz, K. Kunii, I. Kariv, 2010, Cancer research.

An orally available non-nucleotide STING agonist with antitumor activity

Andrew M Haidle, J. Cumming, I. Kariv, 2020, Science.

Interaction of Cardiotonic Thiadiazinone Derivatives with Cardiac Troponin C (*)

B. Pan, R G Johnson, B S Pan, 1996, The Journal of Biological Chemistry.

Discovery of 1-[3-(1-methyl-1H-pyrazol-4-yl)-5-oxo-5H-benzo[4,5]cyclohepta[1,2-b]pyridin-7-yl]-N-(pyridin-2-ylmethyl)methanesulfonamide (MK-8033): A Specific c-Met/Ron dual kinase inhibitor with preferential affinity for the activated state of c-Met.

Wei Lu, Michael D Altman, Craig Rosenstein, 2013, Journal of medicinal chemistry.

Discovery of a Novel cGAMP Competitive Ligand of the Inactive Form of STING.

M. Altman, H. Hatch, B. Pan, 2018, ACS medicinal chemistry letters.

High-Throughput Analysis of HGF-Stimulated Cell Scattering

I. Kariv, A. Szewczak, B. Pan, 2008, Journal of biomolecular screening.

Abstract #3714: In vitro and in vivo antitumor activities of MK-2206, a new allosteric Akt inhibitor

P. Majumder, K. Leander, H. Hatch, 2009 .

Two genetically expressed troponin T fragments representing alpha and beta isoforms exhibit functional differences.

J. Potter, B. Pan, 1992, The Journal of biological chemistry.