A. Bridges

发表

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

Christopher J. Schofield, Cesar Ramirez-Molina, Udo Oppermann, 2012, Nature.

Potential of real-time measurement of GFP-fusion proteins.

A. Bridges, Jolene J. Jones, A. Fosberry, 2004, Journal of biotechnology.

Crystal Structure of Human Cytochrome P450 2D6*

Frank E. Blaney, Sandeep Modi, F. Blaney, 2005, Journal of Biological Chemistry.

Fragment-Based Discovery of Low-Micromolar ATAD2 Bromodomain Inhibitors.

P. Grandi, A. Michon, P. Bamborough, 2015, Journal of medicinal chemistry.

A Qualified Success: Discovery of a New Series of ATAD2 Bromodomain Inhibitors with a Novel Binding Mode Using High-Throughput Screening and Hit Qualification.

P. Grandi, A. Michon, Christina Rau, 2019, Journal of medicinal chemistry.

Enabling Lead Discovery for Histone Lysine Demethylases by High-Throughput RapidFire Mass Spectrometry

Melanie V. Leveridge, Stuart M. Baddeley, C. Chung, 2012, Journal of biomolecular screening.

Over Expression of Wild Type or a Catalytically Dead Mutant of SIRTUIN 6 Does Not Influence NFκB Responses

R. Grimley, C. Chung, J. Vamathevan, 2012, PloS one.

Use of electrospray mass spectrometry to assay chemical reactivity of an acyl carrier protein involved in fatty acid biosynthesis in Saccharopolyspora erythraea

P. Leadlay, J. Staunton, A. Bridges, 1991 .

MrgX2 is a promiscuous receptor for basic peptides causing mast cell pseudo‐allergic and anaphylactoid reactions

A. Bridges, Andrew J. Brown, Zining Wu, 2019, Pharmacology research & perspectives.

Use of electrospray mass spectrometry in enzymic studies on acyl carrier protein implicated in fatty acid biosynthesis in Saccharopolyspora erythraea

P. Leadlay, J. Staunton, A. Bridges, 1991 .

CCR2: characterization of the antagonist binding site from a combined receptor modeling/mutagenesis approach.

I. Forbes, F. Blaney, A. Bridges, 2003, Journal of medicinal chemistry.

Crystallizing Membrane Proteins in the Lipidic Mesophase. Experience with Human Prostaglandin E2 Synthase 1 and an Evolving Strategy

S. T. A. Shah, M. Caffrey, A. Pautsch, 2014, Crystal growth & design.

5-Aryl-4-carboxamide-1,3-oxazoles: potent and selective GSK-3 inhibitors.

P. Bamborough, A. Bridges, S. Belyanskaya, 2012, Bioorganic & medicinal chemistry letters.

Identification of the Binding Site on Cytochrome P450 2B4 for Cytochrome b 5 and Cytochrome P450 Reductase*

I. Vakser, L. Waskell, A. Bridges, 1998, The Journal of Biological Chemistry.

Configuration of a High-Content Imaging Platform for Hit Identification and Pharmacological Assessment of JMJD3 Demethylase Enzyme Inhibitors

Melanie Leveridge, Emma Jones, John Liddle, 2012, Journal of biomolecular screening.

A Model of the Membrane-bound Cytochrome b5-Cytochrome P450 Complex from NMR and Mutagenesis Data*

L. Waskell, N. Popovych, Rui Huang, 2013, The Journal of Biological Chemistry.

Decorating Self-Assembled Peptide Cages with Proteins.

R. Sessions, D. Woolfson, Jordan M Fletcher, 2017, ACS nano.

Demonstrating Enhanced Throughput of RapidFire Mass Spectrometry through Multiplexing Using the JmjD2d Demethylase as a Model System

Peter Francis, Andy West, Melanie Leveridge, 2014, Journal of biomolecular screening.

On the stereospecificity of the coenzyme B12-dependent isobutyryl-CoA mutase reaction

John A. Robinson, B. Moore, D. Nanz, 1995 .

Construction of a 3D model of cytochrome P450 2B4.

G H Loew, I. Vakser, O. Stiffelman, 1997, Protein engineering.

A Model of the Membrane-bound Cytochrome b5-Cytochrome P450 Complex from NMR and Mutagenesis Data*

L. Waskell, N. Popovych, Rui Huang, 2013, The Journal of Biological Chemistry.