P. Thomas

发表

A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

Christopher J. Schofield, Cesar Ramirez-Molina, Udo Oppermann, 2012, Nature.

Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

David M. Wilson, G. Drewes, D. Eberhard, 2015, Nature chemical biology.

A versatile biosynthetic approach to amide bond formation

D. Tew, P. Thomas, S. Lovelock, 2018 .

Design and development of a series of borocycles as selective, covalent kallikrein 5 inhibitors.

A. Hovnanian, J. Liddle, P. Thomas, 2019, Bioorganic & medicinal chemistry letters.

Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 2. Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives.

David M. Wilson, Melanie V. Leveridge, G. Drewes, 2016, Journal of medicinal chemistry.

Structure-based optimisation of orally active & reversible MetAP-2 inhibitors maintaining a tight 'molecular budget'.

P. Thomas, Jonathan D Goodacre, Lena Shukla, 2020, Bioorganic & medicinal chemistry letters.

Configuration of a High-Content Imaging Platform for Hit Identification and Pharmacological Assessment of JMJD3 Demethylase Enzyme Inhibitors

Melanie Leveridge, Emma Jones, John Liddle, 2012, Journal of biomolecular screening.

Approaches to target tractability assessment - a practical perspective.

Michael M. Hann, Kristin K. Brown, Ami S. Lakdawala, 2018, MedChemComm.

The Extent and Impact of Variation in ADME Genes in Sub-Saharan African Populations

Faisal M. Fadlelmola, A. S. Gross, C. Adebamowo, 2020, bioRxiv.

Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-pyridine Carboxylate Derivatives.

Douglas W. Thomson, David M. Wilson, Melanie V. Leveridge, 2016, Journal of medicinal chemistry.