Ruojing Yang

发表

Reversal of Diet-induced Glucose Intolerance by Hepatic Expression of a Variant Glycogen-targeting Subunit of Protein Phosphatase-1*

C. Newgard, A. Depaoli-Roach, R. Gasa, 2002, The Journal of Biological Chemistry.

Hepatic Metabolic Dysfunctions in Type 2 Diabetes: Insulin Resistance and Impaired Glucose Production and Lipid Synthesis

Ruojing Yang, 2011 .

Hepatic Expression of a Targeting Subunit of Protein Phosphatase-1 in Streptozotocin-diabetic Rats Reverses Hyperglycemia and Hyperphagia Despite Depressed Glucokinase Expression*

C. Newgard, Ruojing Yang, 2003, Journal of Biological Chemistry.

Glycogen-targeting Subunits and Glucokinase Differentially Affect Pathways of Glycogen Metabolism and Their Regulation in Hepatocytes*

C. Newgard, M. Brady, A. Sherry, 2002, The Journal of Biological Chemistry.

PGC-1β in the Regulation of Hepatic Glucose and Energy Metabolism*

Jiandie D. Lin, Paul T. Tarr, P. Puigserver, 2003, Journal of Biological Chemistry.

Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells.

Jiandie D. Lin, Paul T. Tarr, B. Spiegelman, 2003, The Journal of biological chemistry.

PGC-1beta in the regulation of hepatic glucose and energy metabolism.

Jiandie D. Lin, Paul T. Tarr, P. Puigserver, 2003, The Journal of biological chemistry.

A Genome-Wide siRNA Screen to Identify Modulators of Insulin Sensitivity and Gluconeogenesis

Xiaohua Douglas Zhang, M. Ferrer, Kenny K. Wong, 2012, PloS one.

c-Jun N-terminal kinase pathways in diabetes.

Ruojing Yang, J. Trevillyan, 2008, The international journal of biochemistry & cell biology.

Suppression of beta cell energy metabolism and insulin release by PGC-1alpha.

P. Puigserver, B. Spiegelman, B. Lowell, 2003, Developmental cell.

Determination of EPAC2 function using EPAC2 null Min6 sublines generated through CRISPR-Cas9 technology

I. Kariv, Haiyan Xu, Ruojing Yang, 2018, Molecular and Cellular Endocrinology.

Identification of N-(1H-pyrazol-4-yl)carboxamide inhibitors of interleukin-1 receptor associated kinase 4: Bicyclic core modifications.

Duan Liu, M. Altman, Ruojing Yang, 2015, Bioorganic & medicinal chemistry letters.

Delivery of RNAi reagents in murine models of obesity and diabetes

E. Bush, P. Jung, C. Rondinone, 2006, Journal of RNAi and gene silencing : an international journal of RNA and gene targeting research.

Hyperlipidemic Effects of Dietary Saturated Fats Mediated through PGC-1β Coactivation of SREBP

Christoph Handschin, Jiandie D. Lin, Bruce M. Spiegelman, 2005, Cell.

Bioenergetic Analysis of Peroxisome Proliferator-activated Receptor γ Coactivators 1α and 1β (PGC-1α and PGC-1β) in Muscle Cells*

Jiandie D. Lin, Paul T. Tarr, B. Spiegelman, 2003, Journal of Biological Chemistry.

Discovery of 5-Amino-N-(1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide Inhibitors of IRAK4.

T. Fischmann, M. Altman, Ruojing Yang, 2015, ACS medicinal chemistry letters.

Suppression of β Cell Energy Metabolism and Insulin Release by PGC-1α

P. Puigserver, B. Spiegelman, B. Lowell, 2003 .

Discovery of potent, selective, orally bioavailable stearoyl-CoA desaturase 1 inhibitors.

Bo Liu, Gang Liu, Hongyu Zhao, 2007, Journal of medicinal chemistry.

Mitochondrial Respiratory Mutants in Yeast Inhibit Glycogen Accumulation by Blocking Activation of Glycogen Synthase*

Ruojing Yang, R. Wek, K. Chun, 1998, The Journal of Biological Chemistry.

Glucose Limitation Induces GCN4Translation by Activation of Gcn2 Protein Kinase

Ruojing Yang, R. Wek, S. A. Wek, 2000, Molecular and Cellular Biology.

The Use of SSMD-Based False Discovery and False Nondiscovery Rates in Genome-Scale RNAi Screens

Marc Ferrer, Joseph F Heyse, Raul Lacson, 2010, Journal of biomolecular screening.

A glucose-responsive insulin therapy protects animals against hypoglycemia.

Margaret S. Wu, M. Erion, D. Kelley, 2018, JCI Insight.

Liver-specific Knockdown of JNK1 Up-regulates Proliferator-activated Receptor γ Coactivator 1β and Increases Plasma Triglyceride despite Reduced Glucose and Insulin Levels in Diet-induced Obese Mice*

E. Bush, P. Jung, C. Rondinone, 2007, Journal of Biological Chemistry.

Establishing and Validating Cellular Functional Target Engagement Assay for Selective IRAK4 Inhibitor Discovery

I. Kariv, Ruojing Yang, Jongwon Lim, 2021, SLAS discovery : advancing life sciences R & D.

Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation.

Duan Liu, T. Fischmann, M. Altman, 2017, Bioorganic & medicinal chemistry letters.

A glucose-responsive insulin therapy protects animals against hypoglycemia.

Margaret S. Wu, M. Erion, D. Kelley, 2018, JCI insight.

Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation.

Duan Liu, T. Fischmann, M. Altman, 2017, Bioorganic & medicinal chemistry letters.

Identification of N-(1H-pyrazol-4-yl)carboxamide inhibitors of interleukin-1 receptor associated kinase 4: Bicyclic core modifications.

Duan Liu, M. Altman, Ruojing Yang, 2015, Bioorganic & medicinal chemistry letters.