C. Cowan

发表

An essential role for MEF2C in the cortical response to loss of sleep in mice

J. Takahashi, R. Greene, G. Konopka, 2020, eLife.

Use of Adeno‐Associated and Herpes Simplex Viral Vectors for In Vivo Neuronal Expression in Mice

W. Carlezon, C. Cowan, Rachel D. Penrod, 2015, Current protocols in neuroscience.

Any Way You Splice It: New Molecular Mechanisms of Cocaine-Induced Alternative Gene Expression

C. Cowan, Rachel D. Penrod, E. Anderson, 2018, Biological Psychiatry.

[35] Enzymology of GTPase acceleration in phototransduction

V. Arshavsky, C. Cowan, T. Wensel, 2000 .

Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 Å

Wei He, Theodore G. Wensel, P. Sigler, 2001, Nature.

RGS proteins: lessons from the RGS9 subfamily.

C. Cowan, T. Wensel, W. He, 2001, Progress in nucleic acid research and molecular biology.

Novel role and regulation of HDAC4 in cocaine‐related behaviors

C. Cowan, S. Maddox, Rachel D. Penrod, 2018, Addiction biology.

REST Acts through Multiple Deacetylase Complexes

Eric C. Griffith, M. Greenberg, C. Cowan, 2001, Neuron.

Peripheral Auditory Nerve Impairment in a Mouse Model of Syndromic Autism

Carolyn M. McClaskey, K. Harris, A. Harrington, 2022, The Journal of Neuroscience.

A novel role for extracellular signal-regulated kinase 5 and myocyte enhancer factor 2 in medulloblastoma cell death.

S. Pomeroy, L. Sturla, John Y. H. Kim, 2005, Cancer research.

Striking a balance in fragile X

C. Cowan, Laura N Smith, 2013, Nature Medicine.

EphB1 and EphB2 intracellular domains regulate the formation of the corpus callosum and anterior commissure

M. Greenberg, C. Cowan, M. Henkemeyer, 2016, Developmental neurobiology.

Phosphorylation of RGS 9-1 by an Endogenous Protein Kinase in Rod Outer Segments *

K. Palczewski, C. Cowan, T. Wensel, 2001 .

Relapse-Associated Transient Synaptic Potentiation Requires Integrin-Mediated Activation of Focal Adhesion Kinase and Cofilin in D1-Expressing Neurons

P. Kalivas, C. Mejias-Aponte, B. Hope, 2020, The Journal of Neuroscience.

The activity-regulated cytoskeleton-associated protein, Arc/Arg3.1, influences mouse cocaine self-administration

C. Cowan, Laura N. Smith, Morgane Thomsen, 2020, Pharmacology Biochemistry and Behavior.

NPAS4 supports drug-cue associations and relapse-like behavior through regulation of the cell type-specific activation balance in the nucleus accumbens

E. Tsvetkov, C. Cowan, Rachel D. Penrod, 2022, bioRxiv.

Clinical findings from the landmark MEF2C ‐related disorders natural history study

S. Skinner, L. Boccuto, C. Cowan, 2022, Molecular genetics & genomic medicine.

Enzymology of GTPase acceleration in phototransduction.

V. Arshavsky, C. Cowan, T. Wensel, 2000, Methods in enzymology.

running title: RGS Proteins

C. Cowan, T. Wensel, 2000 .

Multiple Zinc Binding Sites in Retinal Rod cGMP Phosphodiesterase, PDE6αβ*

C. Cowan, T. Wensel, F. He, 2000, The Journal of Biological Chemistry.

A comparison of the efficiency of G protein activation by ligand-free and light-activated forms of rhodopsin.

C. Cowan, T. Melia, T. Wensel, 1997, Biophysical journal.

RGS9, a GTPase Accelerator for Phototransduction

C. Cowan, T. Wensel, Wei He, 1998, Neuron.

Plexins Are GTPase-Activating Proteins for Rap and Are Activated by Induced Dimerization

Xuewu Zhang, C. Cowan, Jin Jiang, 2012, Science Signaling.

It is a complex issue: emerging connections between epigenetic regulators in drug addiction

C. Cowan, Rachel D. Penrod, M. Taniguchi, 2018, The European journal of neuroscience.

Multiple Autism-Linked Genes Mediate Synapse Elimination via Proteasomal Degradation of a Synaptic Scaffold PSD-95

M. A. Maksimova, George N. DeMartino, C. Cowan, 2012, Cell.

Sex-dependent role for EPHB2 in brain development and autism-associated behavior

E. Tsvetkov, Abha R. Gupta, C. Cowan, 2021, Neuropsychopharmacology.

Guidance molecules in synapse formation and plasticity.

K. Shen, C. Cowan, 2010, Cold Spring Harbor perspectives in biology.

Vav Family GEFs Link Activated Ephs to Endocytosis and Axon Guidance

Eric C. Griffith, M. Greenberg, J. Brugge, 2005, Neuron.

MEF2C Hypofunction in Neuronal and Neuroimmune Populations Produces MEF2C Haploinsufficiency Syndrome–like Behaviors in Mice

E. Tsvetkov, G. Konopka, S. Skinner, 2020, Biological Psychiatry.

MEF2C hypofunction in neuronal and neuroimmune populations cooperate to produce MEF2C haploinsufficiency syndrome-like behaviors in mice

E. Tsvetkov, G. Konopka, S. Skinner, 2019, bioRxiv.

Activity-Dependent Regulation of MEF2 Transcription Factors Suppresses Excitatory Synapse Number

Steven W. Flavell, Eric C. Griffith, M. Greenberg, 2006, Science.

Fragile X Mental Retardation Protein Regulates Synaptic and Behavioral Plasticity to Repeated Cocaine Administration

Mark J. Thomas, Miles R. Fontenot, S. Birnbaum, 2014, Neuron.

Fragile X Mental Retardation Protein Is Required for Synapse Elimination by the Activity-Dependent Transcription Factor MEF2

Brad E. Pfeiffer, M. A. Maksimova, C. Cowan, 2010, Neuron.

CREB Transcriptional Activity in Neurons Is Regulated by Multiple, Calcium-Specific Phosphorylation Events

Eric C. Griffith, R. Dolmetsch, J. Kornhauser, 2002, Neuron.

Activity‐regulated cytoskeleton‐associated protein (Arc/Arg3.1) regulates anxiety‐ and novelty‐related behaviors

C. Cowan, Daniel M. McCalley, Laura N. Smith, 2019, Genes, brain, and behavior.

MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders

Genevieve Konopka, G. Konopka, A. Harrington, 2016, eLife.

Knockdown of the histone di-methyltransferase G9a in nucleus accumbens shell decreases cocaine self-administration, stress-induced reinstatement, and anxiety

E. Nestler, HaoSheng Sun, I. Maze, 2018, Neuropsychopharmacology.

Role of Dorsal Striatum Histone Deacetylase 5 in Incubation of Methamphetamine Craving

E. Nestler, Y. Shaham, J. Bossert, 2017, Biological Psychiatry.

Emerging roles for MEF2 in brain development and mental disorders

A. Harrington, C. Cowan, Ahlem Assali, 2019, Current Opinion in Neurobiology.

Opposing Regulation of Cocaine Seeking by Glutamate and GABA Neurons in the Ventral Pallidum

P. Kalivas, J. Heinsbroek, C. Cowan, 2020, Cell reports.

EphB1 controls long-range cortical axon guidance through a cell non-autonomous role in GABAergic cells

C. Cowan, Ahlem Assali, G. Chenaux, 2023, bioRxiv.

Cloning and Characterization of RGS9-2: A Striatal-Enriched Alternatively Spliced Product of the RGS9 Gene

E. Nestler, C. Cowan, T. Wensel, 1999, The Journal of Neuroscience.

Chronic methamphetamine administration produces cognitive deficits through augmentation of GABAergic synaptic transmission in the prefrontal cortex

A. Lavin, E. Tsvetkov, C. Cowan, 2022, bioRxiv.

A Subset of Nucleus Accumbens Neurons Receiving Dense and Functional Prelimbic Cortical Input Are Required for Cocaine Seeking

Kelsey M. Vollmer, James M. Otis, C. Cowan, 2021, bioRxiv.

Phosphorylation of RGS9-1 by an Endogenous Protein Kinase in Rod Outer Segments*

K. Palczewski, C. Cowan, T. Wensel, 2001, The Journal of Biological Chemistry.

Essential Role for Vav Guanine Nucleotide Exchange Factors in Brain-Derived Neurotrophic Factor-Induced Dendritic Spine Growth and Synapse Plasticity

J. A. Varela, R. Greene, C. Cowan, 2011, The Journal of Neuroscience.

VDCC Voltage-Dependent Calcium Channel WNT Wingless Integration

C. Cowan, Michael A. Robichaux, 2018 .

Eph-Dependent Tyrosine Phosphorylation of Ephexin1 Modulates Growth Cone Collapse

M. Greenberg, S. Shamah, Michael Z. Lin, 2005, Neuron.

Signaling mechanisms of axon guidance and early synaptogenesis.

C. Cowan, Michael A. Robichaux, 2014, Current topics in behavioral neurosciences.

Essential Role of Vav Family Guanine Nucleotide Exchange Factors in EphA Receptor-Mediated Angiogenesis

Dana M. Brantley-Sieders, W. Swat, D. Brantley-Sieders, 2006, Molecular and Cellular Biology.

Dependence of RGS9–1 Membrane Attachment on Its C-terminal Tail*

C. Cowan, T. Melia, T. Wensel, 2001, The Journal of Biological Chemistry.

EphB receptor forward signaling regulates area-specific reciprocal thalamic and cortical axon pathfinding

M. Greenberg, N. Šestan, Kenneth Y. Kwan, 2014, Proceedings of the National Academy of Sciences.

EphB2 receptor forward signaling controls cortical growth cone collapse via Nck and Pak

C. Cowan, M. Henkemeyer, N. Srivastava, 2013, Molecular and Cellular Neuroscience.

Cocaine Regulates MEF2 to Control Synaptic and Behavioral Plasticity

P. Greengard, A. Nairn, E. Nestler, 2008, Neuron.

A Chemical Genetic Approach Reveals Distinct Mechanisms of EphB Signaling During Brain Development

Athar N. Malik, M. Greenberg, Chao Zhang, 2012, Nature Neuroscience.

Emerging roles of actin cytoskeleton regulating enzymes in drug addiction: actin or reactin’?

A. Rothenfluh, C. Cowan, 2013, Current Opinion in Neurobiology.

Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology

P. Greengard, A. Nairn, J. Bibb, 2008, Proceedings of the National Academy of Sciences.

High expression levels in cones of RGS9, the predominant GTPase accelerating protein of rods.

K. Palczewski, C. Cowan, T. Wensel, 1998, Proceedings of the National Academy of Sciences of the United States of America.

HDAC5 and Its Target Gene, Npas4, Function in the Nucleus Accumbens to Regulate Cocaine-Conditioned Behaviors

P. Kalivas, J. Takahashi, Yingxi Lin, 2017, Neuron.

Histone Deacetylase 5 Limits Cocaine Reward through cAMP-Induced Nuclear Import

R. Neve, C. Cowan, Laura N. Smith, 2012, Neuron.

Assessment of Cocaine-induced Behavioral Sensitization and Conditioned Place Preference in Mice.

C. Cowan, Laura N. Smith, Rachel D. Penrod, 2016, Journal of visualized experiments : JoVE.

BDNF-TrkB controls cocaine-induced dendritic spines in rodent nucleus accumbens dissociated from increases in addictive behaviors

E. Nestler, R. Neve, C. Cowan, 2017, Proceedings of the National Academy of Sciences.

Inactivation of NMDA Receptors in the Ventral Tegmental Area during Cocaine Self-Administration Prevents GluA1 Upregulation but with Paradoxical Increases in Cocaine-Seeking Behavior

R. Neve, Allyson K. Friedman, Ming-Hu Han, 2017, The Journal of Neuroscience.

Postsynaptic FMRP bidirectionally regulates excitatory synapses as a function of developmental age and MEF2 activity

M. A. Maksimova, E. Olson, R. Bassel-Duby, 2013, Molecular and Cellular Neuroscience.

An essential role for MEF2C in the cortical response to loss of sleep

J. Takahashi, R. Greene, G. Konopka, 2020, bioRxiv.

Receptor-Mediated Angiogenesis Nucleotide Exchange Factors in EphA Essential Role of Vav Family Guanine

Dana M. Brantley-Sieders, W. Swat, Jin Chen, 2014 .

NPAS4 in the medial prefrontal cortex mediates chronic social defeat stress-induced anhedonia-like behavior and reductions in excitatory synapses

E. Tsvetkov, C. Cowan, Ahlem Assali, 2023, eLife.

NPAS4 in the medial prefrontal cortex mediates chronic social defeat stress-induced anhedonia and dendritic spine loss

C. Cowan, Jaswinder Kumar, M. Scofield, 2021, bioRxiv.

The histone methyltransferase G9a mediates stress‐regulated alcohol drinking

P. Mulholland, C. Cowan, H. Becker, 2021, Addiction biology.