P. Collombat

发表

Pax6 Inactivation in the Adult Pancreas Reveals Ghrelin as Endocrine Cell Maturation Marker

Zeeshan Ahmad, Maria Rafeeq, P. Collombat, 2015, PloS one.

The Ectopic Expression of Pax4 in the Mouse Pancreas Converts Progenitor Cells into α and Subsequently β Cells

O. Madsen, P. Serup, H. Heimberg, 2009, Cell.

Single-cell RNA-seq with spike-in cells enables accurate quantification of cell-specific drug effects in pancreatic islets

C. Bock, S. Kubicek, P. Collombat, 2020, Genome Biology.

Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity

G. Superti-Furga, K. Bennett, A. Stukalov, 2017, Cell.

ghrelin is a novel target of Pax4 in endocrine progenitors of the pancreas and duodenum

Q. Wang, M. Sleeman, J. Houghton, 2008, Developmental dynamics : an official publication of the American Association of Anatomists.

A regulatory path associated with X-linked intellectual disability and epilepsy links KDM5C to the polyalanine expansions in ARX.

J. Gécz, F. Fusco, M. Miano, 2013, American Journal of Human Genetics.

Arx acts as a regional key selector gene in the ventral telencephalon mainly through its transcriptional repression activity.

V. Broccoli, R. Calogero, P. Collombat, 2009, Developmental biology.

Specifying pancreatic endocrine cell fates

P. Serup, J. Hecksher-Sørensen, P. Collombat, 2006, Mechanisms of Development.

Oral idarubicin and low dose cytarabine as the initial treatment of acute myeloid leukemia in elderly patients.

J. Reiffers, P. Hurteloup, P. Collombat, 1991, Leukemia and Lymphoma.

Pax4 acts as a key player in pancreas development and plasticity.

F. Avolio, P. Collombat, A. Vieira, 2015, Seminars in cell & developmental biology.

Pancreatic beta-cells: from generation to regeneration.

H. Heimberg, P. Collombat, A. Mansouri, 2010, Seminars in cell & developmental biology.

Adult duct-lining cells can reprogram into β-like cells able to counter repeated cycles of toxin-induced diabetes.

J. Hecksher-Sørensen, F. Avolio, H. Heimberg, 2013, Developmental cell.

Conversion of Gastrointestinal Somatostatin-Expressing D Cells Into Insulin-Producing Beta-Like Cells Upon Pax4 Misexpression

P. Collombat, N. Druelle, T. Napolitano, 2022, Frontiers in Endocrinology.

Induction of multiple cycles of pancreatic β-cell replacement

F. Avolio, P. Collombat, A. Mansouri, 2013, Cell cycle.

Role of ghrelin in pancreatic development and function

P. Collombat, A. Vieira, T. Napolitano, 2018, Diabetes, obesity & metabolism.

Long-Term GABA Administration Induces Alpha Cell-Mediated Beta-like Cell Neogenesis

O. Madsen, F. Avolio, F. Pattou, 2017, Cell.

Long-TermGABAAdministration Induces AlphaCell-Mediated Beta-like Cell Neogenesis Graphical Abstract Highlights

O. Madsen, F. Avolio, F. Pattou, 2016 .

Double-intensive therapy in high-risk multiple myeloma.

N. Ifrah, P. Collombat, T. Facon, 1992, Blood.

Pax4 and Arx Represent Crucial Regulators of the Development of the Endocrine Pancreas

P. Collombat, A. Mansouri, Tamara Rabe, 2014 .

DNA methylation status correlates with adult β-cell regeneration capacity

M. Cooper, A. El-Osta, P. Collombat, 2021, NPJ Regenerative medicine.

GABA signaling stimulates α-cell-mediated β-like cell neogenesis

F. Avolio, P. Collombat, A. Mansouri, 2017, Communicative & integrative biology.

Opposing actions of Arx and Pax4 in endocrine pancreas development.

Ahmed Mansouri, Peter Gruss, P. Serup, 2003, Genes & development.

GABA triggers pancreatic β-like cell neogenesis

P. Collombat, A. Vieira, N. Ben-Othman, 2017, Cell cycle.

Generation of animals allowing the conditional inactivation of the Pax4 gene

P. Serup, P. Collombat, A. Mansouri, 2012, Transgenic Research.

Oral Idarubicin and Low Dose Cytarabine as the Initial Treatment of Acute Myeloid Elderly Patients in Leukemia

J. Reiffers, P. Hurteloup, P. Collombat, 1991 .

Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity

Christoph Bock, Giulio Superti-Furga, Keiryn L. Bennett, 2017, Cell.

Gfi1 Loss Protects against Two Models of Induced Diabetes

F. Avolio, P. Schmitt‐Kopplin, P. Collombat, 2021, Cells.

β‐Cell replacement as a treatment for type 1 diabetes: an overview of possible cell sources and current axes of research

F. Avolio, P. Collombat, A. Vieira, 2016, Diabetes, obesity & metabolism.

Single-cell RNA-seq with spike-in cells enables accurate quantification of cell-specific drug effects in pancreatic islets

C. Bock, S. Kubicek, P. Collombat, 2020, Genome Biology.

The Homeodomain-Containing Transcription Factors Arx and Pax4 Control Enteroendocrine Subtype Specification in Mice

Anthony Beucher, P. Collombat, Caitlin A. Collin, 2012, PloS one.

Arx Is a Direct Target of Dlx2 and Thereby Contributes to the Tangential Migration of GABAergic Interneurons

J. Rubenstein, F. Valtorta, V. Broccoli, 2008, The Journal of Neuroscience.

Embryonic stem cell-derived neural progenitors as non-tumorigenic source for dopaminergic neurons.

W. Paulus, T. Kuhlmann, C. Trenkwalder, 2014, World journal of stem cells.

Epigenetic Control of Pancreatic Regeneration in Diabetes

P. Collombat, T. Napolitano, Anna Garrido-Utrilla, 2018, Genes.

β-Cell Replacement Strategies: The Increasing Need for a “β-Cell Dogma”

F. Avolio, P. Collombat, A. Vieira, 2017, Front. Genet..

From pancreatic islet formation to beta-cell regeneration.

F. Avolio, P. Collombat, E. Gjernes, 2013, Diabetes research and clinical practice.

Arx and Nkx2.2 compound deficiency redirects pancreatic alpha- and beta-cell differentiation to a somatostatin/ghrelin co-expressing cell lineage

P. Serup, P. Collombat, A. Mansouri, 2011, BMC Developmental Biology.

In vivo conversion of adult α‐cells into β‐like cells: a new research avenue in the context of type 1 diabetes

P. Collombat, E. Gjernes, K. Al-Hasani, 2011, Diabetes, obesity & metabolism.

Reprogramming into pancreatic endocrine cells based on developmental cues

P. Collombat, A. Mansouri, Simon Kordowich, 2010, Molecular and Cellular Endocrinology.

Embryonic endocrine pancreas and mature β cells acquire α and PP cell phenotypes upon Arx misexpression

P. Serup, J. Hecksher-Sørensen, D. Riedel, 2007 .

IA1 is NGN3‐dependent and essential for differentiation of the endocrine pancreas

R. F. Luco, M. Lan, D. Pipeleers, 2006, The EMBO journal.

Genetic determinants of pancreatic epsilon-cell development.

O. Madsen, P. Serup, P. Collombat, 2005, Developmental biology.

The simultaneous loss of Arx and Pax4 genes promotes a somatostatin-producing cell fate specification at the expense of the α- and β-cell lineages in the mouse endocrine pancreas

P. Serup, J. Hecksher-Sørensen, P. Gruss, 2005, Development.

DNA methylation status correlates with adult β-cell regeneration capacity

M. Cooper, A. El-Osta, P. Collombat, 2021, npj Regenerative Medicine.

The Inactivation of Arx in Pancreatic α-Cells Triggers Their Neogenesis and Conversion into Functional β-Like Cells

J. Hecksher-Sørensen, F. Avolio, H. Heimberg, 2013, PLoS genetics.

Embryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression.

P. Serup, J. Hecksher-Sørensen, D. Riedel, 2007, The Journal of clinical investigation.

From pancreas morphogenesis to β-cell regeneration.

F. Avolio, P. Collombat, E. Gjernes, 2013, Current topics in developmental biology.

Wnt Pathway in Pancreatic Development and Pathophysiology

P. Collombat, M. Plaisant, T. Napolitano, 2023, Cells.

Inactivation of Arx, the Murine Ortholog of the X-Linked Lissencephaly with Ambiguous Genitalia Gene, Leads to Severe Disorganization of the Ventral Telencephalon with Impaired Neuronal Migration and Differentiation

J. Rubenstein, V. Broccoli, P. Collombat, 2007, The Journal of Neuroscience.

Histone demethylase KDM5C is a SAHA-sensitive central hub at the crossroads of transcriptional axes involved in multiple neurodevelopmental disorders.

J. Gécz, C. Schwartz, M. Miano, 2019, Human molecular genetics.

A genetic mouse model for progressive ablation and regeneration of insulin producing beta-cells

R. Parlato, P. Collombat, A. Mansouri, 2014, Cell cycle.

Reprogramming into pancreatic endocrine cells based on developmental cues

P. Collombat, A. Mansouri, Simon Kordowich, 2010, Molecular and Cellular Endocrinology.

Sp8 controls the anteroposterior patterning at the midbrain-hindbrain border

A. Simeone, P. Gruss, P. Collombat, 2006, Development.

The homeobox gene Arx is a novel positive regulator of embryonic myogenesis

S. Ferrari, V. Broccoli, G. Cossu, 2008, Cell Death and Differentiation.

In Vivo and In Vitro Tissue‐Specific Expression of Green Fluorescent Protein Using the Cre‐Lox System in Mouse Embryonic Stem Cells

M. Capecchi, H. Fukumitsu, P. Collombat, 2005, Stem cells.

Gastrin: A Distinct Fate of Neurogenin3 Positive Progenitor Cells in the Embryonic Pancreas

Y. Dor, B. Glaser, L. Sussel, 2013, PloS one.

Neurog3 misexpression unravels mouse pancreatic ductal cell plasticity

F. Avolio, P. Collombat, A. Mansouri, 2018, PloS one.

Ectopic expression of Pax4 in pancreatic δ cells results in β-like cell neogenesis

F. Avolio, P. Collombat, A. Mansouri, 2017, The Journal of cell biology.

Generation of animals allowing the conditional inactivation of the Pax4 gene

P. Serup, P. Collombat, A. Mansouri, 2012, Transgenic Research.

Artemisinins Target GABA Receptor Signaling and A Impair a Cell Identity Graphical Abstract Highlights

G. Superti-Furga, K. Bennett, A. Stukalov, 2022 .

Long-Term GABA Administration Induces Alpha Cell-Mediated Beta-like Cell Neogenesis

O. Madsen, F. Avolio, F. Pattou, 2017, Cell.

Pax4 acts as a key player in pancreas development and plasticity.

F. Avolio, P. Collombat, Sergi Navarro, 2015, Seminars in Cell and Developmental Biology.

Turning on the β-cell identity in the pancreas

P. Collombat, A. Mansouri, 2009 .