David G. McEwan

发表

Nix is a selective autophagy receptor for mitochondrial clearance

Ivan Dikic, Volker Dötsch, Philipp Wild, 2010, EMBO reports.

A role for ubiquitin in selective autophagy.

Ivan Dikic, I. Novak, I. Dikic, 2009, Molecular cell.

Phosphorylation of the Autophagy Receptor Optineurin Restricts Salmonella Growth

Sebastian A. Wagner, D. Bumann, V. Dötsch, 2011, Science.

Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling

Owen J. Sansom, Ivan Dikic, Valerie G. Brunton, 2011, Nature Cell Biology.

Not All Autophagy Membranes Are Created Equal

I. Dikic, David G. McEwan, I. Dikič, 2010, Cell.

The Three Musketeers of Autophagy: phosphorylation, ubiquitylation and acetylation.

I. Dikic, David G. McEwan, I. Dikič, 2011, Trends in cell biology.

PLEKHM1 regulates autophagosome-lysosome fusion through HOPS complex and LC3/GABARAP proteins.

I. Dikic, Doris Popovic, C. Behrends, 2015, Molecular cell.

A conserved ATG2‐GABARAP family interaction is critical for phagophore formation

A. Prescott, David G. McEwan, Thomas Macartney, 2020, EMBO reports.

A conserved ATG2-GABARAP interaction is critical for phagophore closure

A. Prescott, David G. McEwan, Thomas Macartney, 2019, bioRxiv.

Structural and Functional Analysis of a Novel Interaction Motif within UFM1-activating Enzyme 5 (UBA5) Required for Binding to Ubiquitin-like Proteins and Ufmylation*

I. Dikic, M. Komatsu, V. Rogov, 2016, The Journal of Biological Chemistry.

Cyclic AMP modulation and its effects on chemo-resistant colon cancer cell proliferation and survival

David G. McEwan, 2008 .

Chemoresistant KM12C colon cancer cells are addicted to low cyclic AMP levels in a phosphodiesterase 4-regulated compartment via effects on phosphoinositide 3-kinase.

G. Baillie, M. Houslay, N. Leslie, 2007, Cancer research.

Palmitoylated small GTPase ARL15 is translocated within Golgi network during adipogenesis

R. Cox, David G. McEwan, Ying Bai, 2021, Biology open.

DRAM‐4 and DRAM‐5 are compensatory regulators of autophagy and cell survival in nutrient‐deprived conditions

K. Ryan, J. O'prey, David G. McEwan, 2022, The FEBS journal.

Host–pathogen interactions and subversion of autophagy

David G. McEwan, 2017, Essays in biochemistry.

kinesin recruitment by adapter SKIP on melanosomes is dynamically controlled by LC3B phosphorylation

Vivek T. Natarajan, S. Sivasubbu, David G. McEwan, 2021, bioRxiv.

Structural and functional analysis of the GABARAP interaction motif (GIM)

V. Dötsch, F. Löhr, I. Dikic, 2016, bioRxiv.

ATG7 is a haploinsufficient repressor of tumor progression and promoter of metastasis

K. Ryan, David G. McEwan, Martina Brucoli, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Attenuation of the Activity of the cAMP-specific Phosphodiesterase PDE4A5 by Interaction with the Immunophilin XAP2*

G. Baillie, M. Houslay, David G. McEwan, 2003, Journal of Biological Chemistry.

Structural basis for phosphorylation-triggered autophagic clearance of Salmonella.

P. Güntert, V. Dötsch, F. Löhr, 2013, The Biochemical journal.

The LC3 interactome at a glance

David G. McEwan, P. Wild, I. Dikič, 2014, Journal of Cell Science.

A role for NBR1 in autophagosomal degradation of ubiquitinated substrates.

M. Komatsu, G. Bjørkøy, T. Lamark, 2009, Molecular cell.

The endolysosomal adaptor PLEKHM1 is a direct target for both mTOR and MAPK pathways

Doris Popovic, D. Krause, David G. McEwan, 2021, FEBS letters.

Src kinase modulates the activation, transport and signalling dynamics of fibroblast growth factor receptors

John K Heath, J. Heath, M. Frame, 2007, EMBO reports.

PLEKHM1 regulates Salmonella-containing vacuole biogenesis and infection.

B. Maček, D. Bumann, A. Frangakis, 2015, Cell host & microbe.

RUFY4 exists as two translationally regulated isoforms, that localize to the mitochondrion in activated macrophages

David G. McEwan, P. Pierre, E. Gatti, 2021, Royal Society Open Science.

Atg8 family proteins, LIR/AIM motifs and other interaction modes

Yasin F. Dagdas, Hong Zhang, V. Rogov, 2023, Autophagy Reports.

Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via CASM

O. Florey, David G. McEwan, J. Durgan, 2023, bioRxiv.

ATG2 and VPS13 proteins: molecular highways transporting lipids to drive membrane expansion and organelle communication

K. Ryan, David G. McEwan, 2021, The FEBS journal.

Cullins keep autophagy under control.

David G. McEwan, I. Dikič, 2014, Developmental cell.

Rab7a and Rab27b control secretion of endothelial microRNA through extracellular vesicles

S. Dimmeler, David G. McEwan, R. Boon, 2015, FEBS letters.

Supplemental Information PLEKHM 1 Regulates Autophagosome-Lysosome Fusion through HOPS Complex and LC 3 / GABARAP Proteins

Doris Popovic, C. Behrends, David G. McEwan, 2014 .

Impact of mesenchymal stromal cell–derived vesicular cargo on B-cell acute lymphoblastic leukemia progression

Valentina R Minciacchi, D. Krause, David G. McEwan, 2022, Blood advances.

LRRK2 phosphorylation status and kinase activity regulate (macro)autophagy in a Rab8a/Rab10-dependent manner

V. Baekelandt, K. Ryan, J. Parys, 2023, Cell death & disease.

PLEKHM1 regulates Salmonella-containing vacuole biogenesis and infection.

B. Maček, D. Bumann, A. Frangakis, 2015, Cell host & microbe.

PLEKHM1: Adapting to life at the lysosome

Ivan Dikic, David G. McEwan, David G McEwan, 2015, Autophagy.