K. Giles

发表

RNA-induced silencing complex (RISC) Proteins PACT, TRBP, and Dicer are SRA binding nuclear receptor coregulators

Xia Li, R. Lanz, B. O’Malley, 2013, Proceedings of the National Academy of Sciences.

RSK1 activation promotes invasion in nodular melanoma

C. Bourque, Y. Houvras, Jinhua Wang, 2015, Journal of Translational Medicine.

Regulation of Epidermal Growth Factor Receptor Signaling in Human Cancer Cells by MicroRNA-7*

John S Mattick, J. Mattick, P. Leedman, 2009, Journal of Biological Chemistry.

Integrated Analysis of miRNA and mRNA Expression in Childhood Medulloblastoma Compared with Neural Stem Cells

Kim W. Carter, Nicholas G. Gottardo, P. Dallas, 2011, PloS one.

The 3′-Untranslated Region of p21WAF1 mRNA Is a Composite cis-Acting Sequence Bound by RNA-binding Proteins from Breast Cancer Cells, Including HuR and Poly(C)-binding Protein*

A. Thomson, P. Leedman, D. Voon, 2003, The Journal of Biological Chemistry.

TUMORIGENESIS AND NEOPLASTIC PROGRESSION Oxidative Phosphorylation Promotes Primary Melanoma Invasion

Y. Houvras, I. Osman, K. Giles, 2020 .

The tumor suppressor microRNA, miR-124a, is regulated by epigenetic silencing and by the transcriptional factor, REST in glioblastoma

A. Boyd, K. Giles, K. McDonald, 2014, Tumor Biology.

Immunotherapy Bridge 2017 and Melanoma Bridge 2017: meeting abstracts

Michael F. Sharpnack, D. Schadendorf, R. Sullivan, 2018, Journal of Translational Medicine.

SLIRP, a small SRA binding protein, is a nuclear receptor corepressor.

R. Lanz, B. O’Malley, J. Wilce, 2006, Molecular cell.

The Evolution of MHC Diversity by Segmental Duplication and Transposition of Retroelements

H. Inoko, L. Balmer, M. Bellgard, 1997, Journal of Molecular Evolution.

Duplication and polymorphism in the MHC: Alu generated diversity and polymorphism within the PERB11 gene family.

J. Kulski, S. Gaudieri, K. Giles, 2004, Hereditas.

mRNA Stability and the Control of Gene Expression: Implications for Human Disease

A. Thomson, P. Leedman, K. Giles, 2002, Neurochemical Research.

Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors

T. Kirchhoff, I. Osman, A. Pavlick, 2018, Journal of Translational Medicine.

Identification of suitable endogenous control genes for microRNA expression profiling of childhood medulloblastoma and human neural stem cells

P. Dallas, K. Carter, Denise Anderson, 2012, BMC Research Notes.

microRNA-7: a tumor suppressor miRNA with therapeutic potential.

P. Leedman, Michael R. Epis, K. Giles, 2014, The international journal of biochemistry & cell biology.

miR-124a is frequently down-regulated in glioblastoma and is involved in migration and invasion.

Helen Wheeler, Sanaz Maleki, Raymond Cook, 2011, European journal of cancer.

How microRNAs modify protein production.

I. Osman, K. Giles, A. Franks, 2015, The Journal of investigative dermatology.

Evolutionary Bioinformatics

Robert B. White, S. Dunlop, D. Forsdyke, 2006, Springer International Publishing.

Identification of a Novel Pathogenic Germline KDR Variant in Melanoma

S. W. Han, T. Kirchhoff, I. Osman, 2015, Clinical Cancer Research.

miR-331-3p and Aurora Kinase inhibitor II co-treatment suppresses prostate cancer tumorigenesis and progression

R. Cohen, P. Leedman, D. Beveridge, 2017, Oncotarget.

miR-331-3p and Aurora Kinase inhibitor II co-treatment suppresses prostate cancer tumorigenesis and progression.

R. Cohen, P. Leedman, D. Beveridge, 2017, Oncotarget.

Integrated analyses of zebrafish miRNA and mRNA expression profiles identify miR-29b and miR-223 as potential regulators of optic nerve regeneration

A. Harvey, K. Carter, K. Giles, 2015, BMC Genomics.

Regulation of Expression of Deoxyhypusine Hydroxylase (DOHH), the Enzyme That Catalyzes the Activation of eIF5A, by miR-331-3p and miR-642-5p in Prostate Cancer Cells*

R. Cohen, A. Barker, P. Leedman, 2012, The Journal of Biological Chemistry.

MicroRNA regulation of growth factor receptor signaling in human cancer cells.

A. Barker, P. Leedman, Michael R. Epis, 2011, Methods in molecular biology.

miR-331-3p Regulates ERBB-2 Expression and Androgen Receptor Signaling in Prostate Cancer*

A. Barker, P. Leedman, Michael R. Epis, 2009, The Journal of Biological Chemistry.

miR-331-3p regulates expression of neuropilin-2 in glioblastoma

P. Leedman, Michael R. Epis, K. Giles, 2013, Journal of Neuro-Oncology.

miRNA-7-5p inhibits melanoma cell migration and invasion.

P. Leedman, Michael R. Epis, K. Giles, 2013, Biochemical and biophysical research communications.

Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes.

H. Bussemaker, P. Schirmacher, D. Grunwald, 2012, Molecular cell.

Matrigel basement membrane matrix influences expression of microRNAs in cancer cell lines.

G. Goodall, A. Tsykin, P. Leedman, 2012, Biochemical and biophysical research communications.

Axl Mediates Acquired Resistance of Head and Neck Cancer Cells to the Epidermal Growth Factor Receptor Inhibitor Erlotinib

G. Goodall, P. Leedman, A. Redfern, 2013, Molecular Cancer Therapeutics.

Regulation of Epidermal Growth Factor Receptor Signaling and Erlotinib Sensitivity in Head and Neck Cancer Cells by miR-7

P. Leedman, Michael R. Epis, K. Giles, 2012, PloS one.

epidermal 1 growth factor receptor inhibitor erlotinib 2 3

G. Goodall, P. Leedman, A. Redfern, 2014 .

Integrated analyses of zebrafish miRNA and mRNA expression profiles identify miR-29b and miR-223 as potential regulators of optic nerve regeneration

A. Harvey, K. Carter, Denise Anderson, 2015, BMC Genomics.

Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA

Diego G. Silva, C. Goodnow, P. Leedman, 2007, Nature.

The Evolution of MHC Diversity by Segmental Duplication and Transposition of Retroelements

H. Inoko, L. Balmer, M. Bellgard, 1997, Journal of Molecular Evolution.

Retroelements and segmental duplications in the generation of diversity within the MHC.

H. Inoko, L. Balmer, J. Kulski, 1997, DNA sequence : the journal of DNA sequencing and mapping.

Regulation of ErbB receptor signalling in cancer cells by microRNA.

A. Barker, P. Leedman, Michael R. Epis, 2010, Current opinion in pharmacology.

Revisiting the Clinical and Biologic Relevance of Partial PTEN Loss in Melanoma.

Jinhua Wang, I. Osman, K. Giles, 2019, The Journal of investigative dermatology.

Novel Binding of HuR and Poly(C)-binding Protein to a Conserved UC-rich Motif within the 3′-Untranslated Region of the Androgen Receptor Messenger RNA*

A. Thomson, J. Wilce, P. Leedman, 2002, The Journal of Biological Chemistry.

Sequence requirements for RNA binding by HuR and AUF1.

J. Wilce, A. Barker, P. Leedman, 2012, Journal of biochemistry.

The RNA-binding Protein HuR Opposes the Repression of ERBB-2 Gene Expression by MicroRNA miR-331-3p in Prostate Cancer Cells*

A. Barker, P. Leedman, D. Beveridge, 2011, The Journal of Biological Chemistry.

BIOMARKERS, GENOMICS, PROTEOMICS, AND GENE REGULATION

C. Bourque, Y. Houvras, E. Hernando-Monge, 2015 .

Oxidative phosphorylation promotes primary melanoma invasion.

Y. Houvras, I. Osman, K. Giles, 2020, The American journal of pathology.

microRNA-7-5p inhibits melanoma cell proliferation and metastasis by suppressing RelA/NF-κB

M. Herlyn, N. Haass, P. Leedman, 2016, Oncotarget.