O. Vagin

发表

Measurement of Internal pH in Helicobacter pylori by Using Green Fluorescent Protein Fluorimetry

G. Sachs, Y. Wen, D. Scott, 2018, Journal of bacteriology.

The gastric HK-ATPase: structure, function, and inhibition

G. Sachs, O. Vagin, K. Munson, 2008, Pflügers Archiv - European Journal of Physiology.

Molecular mechanisms in therapy of acid-related diseases

G. Sachs, I. Modlin, O. Vagin, 2007, Cellular and Molecular Life Sciences.

Electrogenic partial reactions of the gastric H,K-ATPase.

G. Sachs, H. Apell, O. Vagin, 2005, Biophysical journal.

Molecular Modeling of SCH28080 Binding to the Gastric H,K‐ATPase and MgATP Interactions with SERCA‐ and Na,K‐ATPases

G. Sachs, O. Vagin, K. Munson, 2003, Annals of the New York Academy of Sciences.

Characterization of a Novel Potassium-Competitive Acid Blocker of the Gastric H,K-ATPase, 1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine Monofumarate (TAK-438)

G. Sachs, O. Vagin, E. Tokhtaeva, 2011, Journal of Pharmacology and Experimental Therapeutics.

Microsoft Word-27083303-file00.docx

Elmira, O. Vagin, K. Munson, 2011 .

Diverse Pathways for Maturation of the Na,K-ATPase β1 and β2 Subunits in the Endoplasmic Reticulum of Madin-Darby Canine Kidney Cells*

G. Sachs, O. Vagin, E. Tokhtaeva, 2010, The Journal of Biological Chemistry.

HIF and HOIL-1L–mediated PKCζ degradation stabilizes plasma membrane Na,K-ATPase to protect against hypoxia-induced lung injury

A. Ciechanover, J. Sznajder, L. Welch, 2017, Proceedings of the National Academy of Sciences.

Selective Assembly of Na,K-ATPase α2β2 Heterodimers in the Heart

M. Habeck, G. Sachs, L. Dada, 2016, The Journal of Biological Chemistry.

Use of the H,K-ATPase β Subunit to Identify Multiple Sorting Pathways for Plasma Membrane Delivery in Polarized Cells*

G. Sachs, Shahlo Turdikulova, O. Vagin, 2005, Journal of Biological Chemistry.

Helicobacter pylori infection impairs chaperone-assisted maturation of Na,K-ATPase in gastric epithelium.

B. Naini, J. Whitelegge, Y. Wen, 2020, American Journal of Physiology - Gastrointestinal and Liver Physiology.

Topography of the membrane domain of the liver Na+-dependent bile acid transporter.

G. Sachs, Shahlo Turdikulova, O. Vagin, 2005, Biochemistry.

The roles of the Na,K-ATPase beta 1 subunit in pump sorting and epithelial integrity

G. Sachs, O. Vagin, E. Tokhtaeva, 2007, Journal of bioenergetics and biomembranes.

Recombinant Addition of N-Glycosylation Sites to the Basolateral Na,K-ATPase β1 Subunit Results in Its Clustering in Caveolae and Apical Sorting in HGT-1 Cells*

G. Sachs, Shahlo Turdikulova, O. Vagin, 2005, Journal of Biological Chemistry.

A Functional Interaction Between Na,K-ATPase β2-Subunit/AMOG and NF2/Merlin Regulates Growth Factor Signaling in Cerebellar Granule Cells

Sigrid A. Langhans, O. Vagin, E. Tokhtaeva, 2019, Molecular Neurobiology.

Epithelial Junctions Depend on Intercellular Trans-interactions between the Na,K-ATPase β1 Subunits*

G. Sachs, J. Whitelegge, S. Bassilian, 2011, The Journal of Biological Chemistry.

Hypercapnia Impairs Na,K-ATPase Function by Inducing Endoplasmic Reticulum Retention of the β-Subunit of the Enzyme in Alveolar Epithelial Cells

J. Sznajder, W. Seeger, L. Dada, 2020, International journal of molecular sciences.

The control of gastric acid and Helicobacter pylori eradication

G. Sachs, D. Scott, O. Vagin, 2000 .

Review article: the control of gastric acid and Helicobacter pylori eradication.

G. Sachs, D. Scott, O. Vagin, 2000, Alimentary pharmacology & therapeutics.

Dysregulation of ion transport in the lung epithelium infected with SARS-CoV-2

J. Sznajder, L. Dada, O. Vagin, 2021, American journal of physiology. Lung cellular and molecular physiology.

Fatal dysfunction and disintegration of thrombin-stimulated platelets

J. Weisel, O. Kim, M. Alber, 2019, Haematologica.

Contribution of septins to human platelet structure and function

J. Weisel, E. Bi, O. Kim, 2022, iScience.

Plasma membrane delivery of the gastric H,K-ATPase: the role of beta-subunit glycosylation.

G. Sachs, O. Vagin, S. Denevich, 2003, American journal of physiology. Cell physiology.

Inverse correlation between the extent of N-glycan branching and intercellular adhesion in epithelia. Contribution of the Na,K-ATPase beta1 subunit.

G. Sachs, O. Vagin, E. Tokhtaeva, 2008, The Journal of biological chemistry.

The Role of the β1 Subunit of the Na,K-ATPase and Its Glycosylation in Cell-Cell Adhesion*

G. Sachs, O. Vagin, E. Tokhtaeva, 2006, Journal of Biological Chemistry.

Analysis of N- and O-Glycosylation of Lysosomal Glycoproteins.

O. Vagin, E. Tokhtaeva, A. Gukovskaya, 2017, Methods in molecular biology.

The Gastric H,K ATPase as a Drug Target: Past, Present, and Future

G. Sachs, O. Vagin, K. Munson, 2007, Journal of clinical gastroenterology.

Maturation of the Na,K-ATPase in the Endoplasmic Reticulum in Health and Disease

J. Sznajder, L. Dada, O. Vagin, 2021, The Journal of Membrane Biology.

The Na-K-ATPase α₁β₁ heterodimer as a cell adhesion molecule in epithelia.

G. Sachs, L. Dada, O. Vagin, 2012, American journal of physiology. Cell physiology.

N-glycan-dependent quality control of the Na,K-ATPase beta(2) subunit.

G. Sachs, O. Vagin, E. Tokhtaeva, 2010, Biochemistry.

Inverse Correlation between the Extent of N-Glycan Branching and Intercellular Adhesion in Epithelia

G. Sachs, O. Vagin, E. Tokhtaeva, 2008, Journal of Biological Chemistry.

Polarized membrane distribution of potassium-dependent ion pumps in epithelial cells: Different roles of the N-glycans of their β subunits

Shahlo Turdikulova, O. Vagin, E. Tokhtaeva, 2007, Cell Biochemistry and Biophysics.

Comparison of Covalent with Reversible Inhibitor Binding Sites of the Gastric H,K-ATPase by Site-directed Mutagenesis*

G. Sachs, O. Vagin, K. Munson, 2000, The Journal of Biological Chemistry.

Assembly with the Na,K-ATPase α 1 Subunit Is Required for Export of β 1 and β 2 Subunits from the Endoplasmic Reticulum

G. Sachs, O. Vagin, E. Tokhtaeva, 2010 .

Assembly with the Na,K-ATPase alpha(1) subunit is required for export of beta(1) and beta(2) subunits from the endoplasmic reticulum.

G. Sachs, O. Vagin, E. Tokhtaeva, 2009, Biochemistry.

FXYD5 Is an Essential Mediator of the Inflammatory Response during Lung Injury

J. Sznajder, H. Perlman, L. Dada, 2017, Front. Immunol..

High CO2 Leads to Na,K-ATPase Endocytosis via c-Jun Amino-Terminal Kinase-Induced LMO7b Phosphorylation

Yosef Gruenbaum, Julian P. Whitelegge, István Vadász, 2015, Molecular and Cellular Biology.

Helicobacter pylori impedes acid-induced tightening of gastric epithelial junctions.

G. Sachs, D. Scott, E. Marcus, 2013, American journal of physiology. Gastrointestinal and liver physiology.

Septins: Regulators of Protein Stability

O. Vagin, D. Beenhouwer, 2016, Front. Cell Dev. Biol..

The role of the beta1 subunit of the Na,K-ATPase and its glycosylation in cell-cell adhesion.

G. Sachs, O. Vagin, E. Tokhtaeva, 2006, The Journal of biological chemistry.

Septin Dynamics Are Essential for Exocytosis*

G. Sachs, J. Whitelegge, L. Dada, 2015, The Journal of Biological Chemistry.

Lysosome-Associated Membrane Proteins (LAMP) Maintain Pancreatic Acinar Cell Homeostasis: LAMP-2–Deficient Mice Develop Pancreatitis

J. Mayerle, M. Lerch, R. Lüllmann-Rauch, 2015, Cellular and molecular gastroenterology and hepatology.

Current trends in the treatment of upper gastrointestinal disease.

G. Sachs, D. Scott, O. Vagin, 2002, Best practice & research. Clinical gastroenterology.

Identification of the amino acid region involved in the intercellular interaction between the β1 subunits of Na+/K+-ATPase

G. Sachs, J. Sznajder, L. Dada, 2012, Journal of Cell Science.

Septin oligomerization regulates persistent expression of ErbB2/HER2 in gastric cancer cells.

G. Sachs, J. Whitelegge, D. Scott, 2016, The Biochemical journal.

Role of N-glycosylation in trafficking of apical membrane proteins in epithelia.

G. Sachs, O. Vagin, J. Kraut, 2009, American journal of physiology. Renal physiology.

The O-glycosylated ectodomain of FXYD5 impairs adhesion by disrupting cell–cell trans-dimerization of Na,K-ATPase β1 subunits

G. Sachs, J. Sznajder, L. Dada, 2016, Journal of Cell Science.

Net Protein Breakdown, and Increased IL-6 Release Placebo-Controlled, Bilaterally Infused Human Leg: Increased Insulin Sensitivity, Increased on Local Fuel Metabolism and Cytokine Levels in the

G. Sachs, K. Ryan, J. Whitelegge, 2015 .

Subunit Isoform Selectivity in Assembly of Na,K-ATPase α-β Heterodimers*

G. Sachs, J. Kaplan, O. Vagin, 2012, The Journal of Biological Chemistry.

The cryo-EM structure of gastric H+,K+-ATPase with bound BYK99, a high-affinity member of K+-competitive, imidazo[1,2-a]pyridine inhibitors

G. Sachs, Hiroshi Suzuki, K. Tani, 2017, Scientific Reports.

SCH28080, a K+-competitive inhibitor of the gastric H,K-ATPase, binds near the M5-6 luminal loop, preventing K+ access to the ion binding domain.

G. Sachs, O. Vagin, K. Munson, 2002, Biochemistry.

The H,K-ATPase β Subunit as a Model to Study the Role of N-Glycosylation in Membrane Trafficking and Apical Sorting*

G. Sachs, O. Vagin, S. Turdikulova, 2004, Journal of Biological Chemistry.

Mutational analysis of the K+-competitive inhibitor site of gastric H,K-ATPase.

G. Sachs, O. Vagin, K. Munson, 2001, Biochemistry.

Recruitment of septin cytoskeletal proteins by botulinum toxin A protease determines its remarkable stability

George Sachs, Julian P Whitelegge, Puneet Souda, 2014, Journal of Cell Science.

Reorganization of Septins Modulates Synaptic Transmission at Neuromuscular Junctions

O. Vagin, A. Skorinkin, L. Nurullin, 2019, Neuroscience.

Characterization of a Novel Potassium-Competitive Acid Blocker of the Gastric H,K-ATPase, 1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine Monofumarate (TAK-438)

G. Sachs, O. Vagin, E. Tokhtaeva, 2011, Journal of Pharmacology and Experimental Therapeutics.

Gastric H+,K+-ATPase

O. Vagin, K. Munson, J. Shin, 2008 .

Helicobacter pylori-Induced Decrease in Membrane Expression of Na,K-ATPase Leads to Gastric Injury

O. Vagin, E. Tokhtaeva, Muriel Larauche, 2024, Biomolecules.

Inhibition Kinetics of the Gastric H,K‐ATPase by K‐Competitive Inhibitor SCH28080 as a Tool for Investigating the Luminal Ion Pathway

G. Sachs, O. Vagin, K. Munson, 2003, Annals of the New York Academy of Sciences.

Gastric H+,K+-ATPase

O. Vagin, J. Shin, George Sachs, 2004 .