M. Gorman

发表

Reaction mechanism of the bioluminescent protein mnemiopsin1 revealed by X-ray crystallography and QM/MM simulations

M. Parker, H. Naderi-manesh, M. Taghdir, 2018, The Journal of Biological Chemistry.

M van Heel, P A Bates, P. Bates, 2000, Molecular cell.

The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra‐helical deoxyribose at DNA abasic sites

J. Tainer, P. Freemont, E. de La Fortelle, 1997, The EMBO journal.

A structural view of PA2G4 isoforms with opposing functions in cancer

M. Parker, J. Holien, M. Gorman, 2020, The Journal of Biological Chemistry.

Crystallization and preliminary X-ray analysis of glutathione transferases from cyanobacteria.

M. Parker, S. Feil, G. Stenberg, 2009, Acta crystallographica. Section F, Structural biology and crystallization communications.

The structure and functions of the HAP1/Ref-1 protein.

P. Freemont, I. Hickson, S. Moréra, 1997, Oncology research.

Crystal structure of the mitochondrial chaperone TIM9.10 reveals a six-bladed alpha-propeller.

J. Gulbis, M. Lazarou, M. Gorman, 2006, Molecular cell.

Determinants of oligosaccharide specificity of the carbohydrate-binding modules of AMP-activated protein kinase.

M. Parker, D. Stapleton, M. Gorman, 2015, The Biochemical journal.

Crystallization and preliminary X-ray diffraction studies of pancreatic spasmolytic polypeptide.

P. Freemont, A. De, M. Gorman, 1992, Journal of molecular biology.

Crystal structure of the Leishmania major MIX protein: A scaffold protein that mediates protein–protein interactions

M. Parker, A. Papenfuss, M. Perugini, 2011, Protein Science.

Structure of the lysine specific protease Kgp from Porphyromonas gingivalis, a target for improved oral health

M. Parker, S. Feil, B. Michell, 2015, Protein science : a publication of the Protein Society.

Structural Basis for Receptor Recognition by the Human CD59-Responsive Cholesterol-Dependent Cytolysins.

M. Parker, C. Morton, S. Feil, 2016, Structure.

Structural Determinants Defining the Allosteric Inhibition of an Essential Antibiotic Target.

M. Parker, M. Perugini, G. Jameson, 2016, Structure.

Structure of the Janus protein human CLIC2.

Paul M G Curmi, Michael W Parker, P. Curmi, 2007, Journal of molecular biology.

From Knock-Out Phenotype to Three-Dimensional Structure of a Promising Antibiotic Target from Streptococcus pneumoniae

M. Parker, M. Perugini, G. Jameson, 2013, PloS one.

Crystal structure of a disulfide-linked "trefoil" motif found in a large family of putative growth factors.

P. Freemont, A. De, M. Gorman, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Recognition and detoxification of the insecticide DDT by Drosophila melanogaster glutathione S-transferase D1.

W. Low, P. Batterham, C. Robin, 2010, Journal of molecular biology.

Drugging MYCN oncogenic signalling through the MYCN-PA2G4 binding interface.

M. Fischer, A. Oberthuer, M. Parker, 2019, Cancer research.

Crystal Structure of the Mitochondrial Chaperone Tim9 10 Reveals a Six-bladed A-propeller

J. Gulbis, M. Lazarou, M. Gorman, 2022 .

Substrate Locking Promotes Dimer-Dimer Docking of an Enzyme Antibiotic Target.

Cyril F. Reboul, A. Buckle, M. Parker, 2018, Structure.

Inhibitors of the Oncogenic PA2G4-MYCN Protein-Protein Interface

M. Parker, J. Holien, M. Gorman, 2023, Cancers.

Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation

M. Parker, C. Morton, S. Feil, 2015, Scientific Reports.

Structure and Functions of the Major Human AP Endonuclease HAP1/Ref-1

P. Freemont, I. Hickson, M. Gorman, 2001 .

Crystallization of dihydrodipicolinate synthase from a clinical isolate of Streptococcus pneumoniae.

M. Parker, M. Perugini, M. Gorman, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

The purification, crystallization and preliminary X-ray diffraction analysis of dihydrodipicolinate synthase from Clostridium botulinum.

J. Newman, M. Parker, M. Perugini, 2008, Acta crystallographica. Section F, Structural biology and crystallization communications.

Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling.

Michael W Parker, M. Dottore, Angel F. Lopez, 2016, Structure.

QM/MM simulations provide insight into the mechanism of bioluminescence triggering in ctenophore photoproteins

M. Parker, H. Naderi-manesh, M. Taghdir, 2017, PloS one.

The Structural Basis for a Transition State That Regulates Pore Formation in a Bacterial Toxin

M. Parker, C. Morton, S. Panjikar, 2019, mBio.

Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding

B. Kemp, M. Parker, K. Sakamoto, 2016, Nature Communications.

Purification, crystallization, small-angle X-ray scattering and preliminary X-ray diffraction analysis of the SH2 domain of the Csk-homologous kinase.

M. Parker, R. Dobson, T. Mulhern, 2011, Acta crystallographica. Section F, Structural biology and crystallization communications.

Substitution of Asp-210 in HAP1 (APE/Ref-1) eliminates endonuclease activity but stabilises substrate binding.

P. Freemont, I. Hickson, M. Gorman, 2000, Nucleic acids research.

Expression, purification, crystallization and preliminary X-ray diffraction analysis of chloride intracellular channel 2 (CLIC2).

Michael W Parker, M. Parker, J. Adams, 2007, Acta crystallographica. Section F, Structural biology and crystallization communications.

Cloning, expression and crystallization of dihydrodipicolinate reductase from methicillin-resistant Staphylococcus aureus.

M. Parker, M. Perugini, R. Dobson, 2010, Acta crystallographica. Section F, Structural biology and crystallization communications.

Identification of p8,14 as a highly abundant heterodimeric calcium binding protein complex of myeloid cells.

N. Hogg, P. Freemont, M. Gorman, 1991, The Journal of biological chemistry.

1060 Crystal structure of the Leishmania major MIX protein : A scaffoldprotein that mediates protein-protein interactions

M. Sawaya, S. Mochrie, A. Papenfuss, 2011 .