D. Engman

发表

Molecular Determinants of Ciliary Membrane Localization of Trypanosoma cruzi Flagellar Calcium-binding Protein*

Danijela Maric, B. McGwire, K. T. Buchanan, 2011, The Journal of Biological Chemistry.

Flagellar protein localization mediated by a calcium–myristoyl/palmitoyl switch mechanism

D. Engman, L. Godsel, 1999, The EMBO journal.

Enhanced Efferocytosis of Apoptotic Cardiomyocytes Through Myeloid-Epithelial-Reproductive Tyrosine Kinase Links Acute Inflammation Resolution to Cardiac Repair After Infarction

S. Homma, S. Miller, D. Vaughan, 2013, Circulation research.

Trypanosoma cruzi heat-shock protein 90 can functionally complement yeast.

R. Tibbetts, D. Engman, D. Picard, 1995, Molecular and biochemical parasitology.

Acylation in trypanosomatids: an essential process and potential drug target.

D. Engman, K. Paul, Amanda M Goldston, 2014, Trends in parasitology.

Heat-Killed Trypanosoma cruzi Induces Acute Cardiac Damage and Polyantigenic Autoimmunity

C. Epting, D. Engman, M. Daniels, 2011, PloS one.

Trypanosoma cruzi GP63 Proteins Undergo Stage-Specific Differential Posttranslational Modification and Are Important for Host Cell Infection

B. McGwire, C. Olson, D. Engman, 2009, Infection and Immunity.

Modulation of Autoimmunity by Treatment of an Infectious Disease

N. Giafis, D. Engman, M. Daniels, 2007, Infection and Immunity.

Induction of cardiac autoimmunity in Chagas heart disease: A case for molecular mimicry

J. Kalil, D. Engman, S. Fonseca, 2006, Autoimmunity.

A Cardiac Myosin-Specific Autoimmune Response Is Induced by Immunization with Trypanosoma cruzi Proteins

D. Engman, M. Daniels, J. Leon, 2004, Infection and Immunity.

Myosin Autoimmunity Is Not Essential for Cardiac Inflammation in Acute Chagas’ Disease 1

D. Engman, J. Leon, Kegiang Wang, 2003, The Journal of Immunology.

Pathogenesis of Chagas heart disease: role of autoimmunity.

D. Engman, J. Leon, J. León, 2002, Acta tropica.

Carcinoid tumors of the thymus and Cushing's syndrome: Clinicopathologic features and current best evidence regarding the cell of origin of these unusual neoplasms.

A. Marchevsky, D. Engman, A. Walts, 2019, Annals of diagnostic pathology.

The significance of autoimmunity in the pathogenesis of Chagas heart disease.

D. Engman, J. Leon, J. León, 2003, Frontiers in bioscience : a journal and virtual library.

TcDJ1, a putative mitochondrial DnaJ protein in Trypanosoma cruzi.

R. Tibbetts, S. Goldenberg, C. Olson, 1998, FEMS microbiology letters.

Precision Health for Chagas Disease: Integrating Parasite and Host Factors to Predict Outcome of Infection and Response to Therapy

D. Engman, P. Romano, S. J. Martínez, 2020, Frontiers in Cellular and Infection Microbiology.

Treatment of experimental myocarditis via modulation of the renin-angiotensin system.

D. Engman, M. Daniels, Kenneth V Hyland, 2007, Current pharmaceutical design.

Enhanced Efferocytosis of Apoptotic Cardiomyocytes Through MER Tyrosine Kinase Links Acute Inflammation Resolution to Cardiac Repair After Infarction

S. Homma, S. Miller, D. Vaughan, 2013 .

Comparison of HSP70 genes from two strains of Trypanosoma cruzi.

S. R. Sias, J. Donelson, D. Engman, 1989, Molecular and biochemical parasitology.

Trypanosoma cruzi exhibits inter- and intra-strain heterogeneity in molecular karyotype and chromosomal gene location.

J. Donelson, D. Engman, L. Kirchhoff, 1987, Molecular and biochemical parasitology.

Endothelial Transmigration by Trypanosoma cruzi

C. Olson, C. Epting, D. Engman, 2013, PloS one.

Flagellar membrane trafficking in kinetoplastids

K. T. Buchanan, D. Engman, A. Fridberg, 2006, Parasitology Research.

A Flagellum-specific Calcium Sensor*

K. T. Buchanan, C. Olson, D. Engman, 2005, Journal of Biological Chemistry.

Flagellar membrane localization via association with lipid rafts

T. Hazlett, C. Olson, D. Engman, 2009, Journal of Cell Science.

Sphingolipid synthesis is necessary for kinetoplast segregation and cytokinesis in Trypanosoma brucei

C. Olson, D. Engman, I. Almeida, 2008, Journal of Cell Science.

Molecular mechanisms of protein and lipid targeting to ciliary membranes

Danijela Maric, Brian T. Emmer, D. Engman, 2010, Journal of Cell Science.

Depletion of regulatory T cells decreases cardiac parasitosis and inflammation in experimental Chagas disease

C. Epting, D. Engman, E. Thorp, 2015, Parasitology Research.

Recombinant cardiac myosin fragment induces experimental autoimmune myocarditis via activation of Th1 and Th17 immunity

D. Engman, M. Daniels, Kenneth V Hyland, 2008, Autoimmunity.

Captopril Ameliorates Myocarditis in Acute Experimental Chagas Disease

D. Engman, J. Leon, Kegiang Wang, 2003, Circulation.

Angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists in experimental myocarditis.

D. Engman, L. Godsel, J. Leon, 2003, Current pharmaceutical design.

Comparison of angiotensin converting enzyme inhibition and angiotensin II receptor blockade for the prevention of experimental autoimmune myocarditis.

D. Engman, M. Daniels, J. Leon, 2008, International journal of cardiology.

The major surface‐metalloprotease of the parasitic protozoan, Leishmania, protects against antimicrobial peptide‐induced apoptotic killing

W. McMaster, B. McGwire, D. Engman, 2006, Molecular microbiology.

Autoimmune pathogenesis of Chagas heart disease: looking back, looking ahead.

D. Engman, K. M. Bonney, K. Bonney, 2015, The American journal of pathology.

Captopril Prevents Experimental Autoimmune Myocarditis 1

J. Fornek, D. Engman, L. Godsel, 2003, The Journal of Immunology.

Cardiac antigen-specific autoantibody production is associated with cardiomyopathy in Trypanosoma cruzi-infected mice.

R. Tibbetts, S. Miller, D. Engman, 1994, Journal of immunology.

Are MD-PhD Programs Meeting Their Goals? An Analysis of Career Choices Made by Graduates of 24 MD-PhD Programs

M. Akabas, C. Wiley, D. Engman, 2010, Academic medicine : journal of the Association of American Medical Colleges.

Killing of African trypanosomes by antimicrobial peptides.

B. McGwire, C. Olson, D. Engman, 2003, The Journal of infectious diseases.

International Journal for Parasitology 31 (2001) 472±481 www.parasitology-online.com Invited Review The life cycle of Trypanosoma cruzi revisited

D. Engman, K. Tyler, 2001 .

Molecular Comparison of the Mitochondrial and Cytoplasmic hsp 70 of Trypanosoma cruzi, Trypanosoma brucei and Leishmania major

Karin Klein, J. Donelson, C. Olson, 1995, The Journal of eukaryotic microbiology.

Molecular cloning and characterization of the 78-kilodalton glucose-regulated protein of Trypanosoma cruzi

R. Tibbetts, C. Olson, D. Engman, 1994, Infection and immunity.

Acylation-dependent Export of Trypanosoma cruzi Phosphoinositide-specific Phospholipase C to the Outer Surface of Amastigotes*

Danijela Maric, D. Engman, R. Docampo, 2010, The Journal of Biological Chemistry.

Identification of calcium binding sites in the trypanosome flagellar calcium-acyl switch protein.

S. Goldenberg, D. Engman, L. Godsel, 1999, Molecular and biochemical parasitology.

The Lipid Raft Proteome of African Trypanosomes Contains Many Flagellar Proteins

C. Olson, D. Engman, Aabha I Sharma, 2017, Pathogens.

TMPRSS2 activity may mediate sex differences in COVID-19 severity

D. Engman, S. You, Derick Okwan-Duodu, 2021, Signal Transduction and Targeted Therapy.

Homologues of the 24-kDa flagellar Ca(2+)-binding protein gene of Trypanosoma cruzi are present in other members of the Trypanosomatidae family.

J. Linss, S. Goldenberg, C. Olson, 1997, Experimental parasitology.

Captopril Administration Suppresses DTH but Not Humoral Immune Responses in Infected Mice

D. Engman, J. Leon, Kegiang Wang, 2003 .

Cardiac Myosin Autoimmunity in Acute Chagas' Heart Disease

D. Engman, L. Godsel, Kegiang Wang, 2001, Infection and Immunity.

Prevention of Autoimmune Myocarditis Through the Induction of Antigen-Specific Peripheral Immune Tolerance

S. Miller, D. Engman, L. Godsel, 2001, Circulation.

Leishmaniasis and Chagas disease: Is there hope in nanotechnology to fight neglected tropical diseases?

D. Scariot, D. Engman, E. Scott, 2022, Frontiers in Cellular and Infection Microbiology.

Effects of cannabinoid treatment on Chagas disease pathogenesis: balancing inhibition of parasite invasion and immunosuppression

S. Miller, D. Engman, K. Tyler, 2005, Cellular microbiology.

Correction: Heat-Killed Trypanosoma cruzi Induces Acute Cardiac Damage and Polyantigenic Autoimmunity

C. Epting, D. Engman, M. Daniels, 2011, PLoS ONE.

Molecular Cloning of mtp7O, a Mitochondrial Member of the hsp7O Family

J. Donelson, D. Engman, 2022 .

Chagas heart disease pathogenesis: one mechanism or many?

D. Engman, K. M. Bonney, K. Bonney, 2008, Current molecular medicine.

Mitochondrial heat shock protein 70 is distributed throughout the mitochondrion in a dyskinetoplastic mutant of Trypanosoma brucei.

C. Olson, D. Engman, K. G. Klein, 1995, Molecular and biochemical parasitology.

Trypanosoma brucei Acyl-Protein Thioesterase-like (TbAPT-L) Is a Lipase with Esterase Activity for Short and Medium-Chain Fatty Acids but Has No Depalmitoylation Activity

M. Bogyo, B. Dickinson, C. Olson, 2022, Pathogens.

Pathology and Pathogenesis of Chagas Heart Disease.

D. Engman, N. Garg, D. Luthringer, 2019, Annual review of pathology.

Composition and sensory function of the trypanosome flagellar membrane.

Danijela Maric, C. Epting, D. Engman, 2010, Current opinion in microbiology.

Migration through the Extracellular Matrix by the Parasitic Protozoan Leishmania Is Enhanced by Surface Metalloprotease gp63

K. Chang, B. McGwire, D. Engman, 2003, Infection and Immunity.

Calflagin Inhibition Prolongs Host Survival and Suppresses Parasitemia in Trypanosoma brucei Infection

Brian T. Emmer, C. Epting, D. Engman, 2010, Eukaryotic Cell.

Molecular mechanisms of host cell invasion by Trypanosoma cruzi.

C. Epting, D. Engman, B. Coates, 2010, Experimental parasitology.

Sterol targeting drugs reveal life cycle stage-specific differences in trypanosome lipid rafts

C. Olson, C. Epting, D. Engman, 2017, Scientific Reports.

Flagellar elongation induced by glucose limitation is preadaptive for Trypanosoma cruzi differentiation.

D. Engman, K. Tyler, 2000, Cell motility and the cytoskeleton.

Bioluminescent imaging of Trypanosoma cruzi infection.

C. Olson, D. Engman, M. Daniels, 2008, International journal for parasitology.

The 35-nucleotide spliced leader sequence is common to all trypanosome messenger RNA's.

J. Donelson, D. Dorfman, D. Engman, 1986, Science.

A mitochondrial heat shock protein from Crithidia fasciculata.

J. Donelson, D. Engman, P. T. Englund, 1993, Molecular and biochemical parasitology.

Comparison of Large, Medium, and Small Solid Tumor Gene Panels for Detection of Clinically Actionable Mutations in Cancer

R. Figlin, J. Xu, S. Alkan, 2020, Targeted Oncology.

Molecular cloning of mtp70, a mitochondrial member of the hsp70 family

J. Donelson, D. Engman, L. Kirchhoff, 1989, Molecular and cellular biology.

Protein Composition Reflects Extracellular Vesicle Heterogeneity

D. Di Vizio, D. Engman, Andrew R. Chin, 2019, Proteomics.

The DnaJ family of protein chaperones in Trypanosoma cruzi.

R. Tibbetts, C. Olson, D. Engman, 1998, Molecular and biochemical parasitology.

Utility of recombinant flagellar calcium-binding protein for serodiagnosis of Trypanosoma cruzi infection

R. Tibbetts, C. Olson, D. Engman, 1995, Journal of clinical microbiology.

Comparison of the 24 kDa Flagellar Calcium‐Binding Protein cDNA of Two Strains of Trypanosoma cruzi

C. Olson, D. Engman, L. Godsel, 1995, The Journal of eukaryotic microbiology.

Expression and localization of Trypanosoma cruzi hsp60.

C. Olson, D. Engman, A. Winquist, 1994, Molecular and biochemical parasitology.

Cardiac damage induced by immunization with heat‐killed Trypanosoma cruzi is not antibody mediated

D. Engman, K. Bonney, J. M. Taylor, 2013, Parasite immunology.

Nanocarrier-enhanced intracellular delivery of benznidazole for treatment of Trypanosoma cruzi infection

D. Scariot, C. Olson, D. Engman, 2021, JCI insight.

The gene family encoding eggshell proteins of Schistosoma japonicum.

J. Donelson, D. Engman, G. Cain, 1990, Molecular and biochemical parasitology.

Depletion of regulatory T cells decreases cardiac parasitosis and inflammation in experimental Chagas disease

C. Epting, D. Engman, E. Thorp, 2015, Parasitology Research.

Repurposing Carvedilol as a Novel Inhibitor of the Trypanosoma cruzi Autophagy Flux That Affects Parasite Replication and Survival

D. Engman, J. Clos, C. Labriola, 2021, Frontiers in Cellular and Infection Microbiology.

Sphingosine Kinase Regulates Microtubule Dynamics and Organelle Positioning Necessary for Proper G1/S Cell Cycle Transition in Trypanosoma brucei

C. Olson, C. Epting, D. Engman, 2015, mBio.

American Trypanosomiasis

M. Miles, D. Engman, K. Tyler, 2003, World Class Parasites.

Molecular and biochemical comparison of the 70-kDa heat shock proteins of Trypanosoma cruzi.

J. Donelson, C. Walsh, C. Olson, 1994, Journal of Biological Chemistry.

Dynamic protein S-palmitoylation mediates parasite life cycle progression and diverse mechanisms of virulence

D. Engman, Robert W. B. Brown, Aabha I. Sharma, 2017, Critical reviews in biochemistry and molecular biology.

Global Analysis of Protein Palmitoylation in African Trypanosomes

Hyungwon Choi, A. Nesvizhskii, C. Epting, 2010, Eukaryotic Cell.

Human antibody responses to Trypanosoma cruzi 70-kD heat-shock proteins.

D. Engman, L. Godsel, J. D. Peterson, 1998, The American journal of tropical medicine and hygiene.

The Contribution of Autoimmunity to Chagas Heart Disease

D. Engman, J. León, 2003 .

Leon and Engman The Contribution of Autoimmunity to Chagas Heart Disease

D. Engman, D. M. Engman, J. León, 2002 .

Extracellular Release of the Glycosylphosphatidylinositol (GPI)-linked Leishmania Surface Metalloprotease, gp63, Is Independent of GPI Phospholipolysis

K. Chang, B. McGwire, D. Engman, 2002, The Journal of Biological Chemistry.

Further thoughts on where we stand on the autoimmunity hypothesis of Chagas disease.

D. Engman, Kenneth V. Hyland, 2006, Trends in parasitology.

Identification of a palmitoyl acyltransferase required for protein sorting to the flagellar membrane

C. Olson, Brian T. Emmer, C. Epting, 2009, Journal of Cell Science.

Autoimmunity in Chagas heart disease.

D. Engman, J. León, Juan S. Leon, 2001, International journal for parasitology.

NMR structure of the calflagin Tb24 flagellar calcium binding protein of Trypanosoma brucei

Xianzhong Xu, C. Olson, D. Engman, 2012, Protein science : a publication of the Protein Society.

1H, 15N, and 13C chemical shift assignments of the calflagin Tb24 flagellar calcium binding protein of Trypanosoma brucei

Xianzhong Xu, C. Olson, D. Engman, 2012, Biomolecular NMR Assignments.

Structural Insights into Membrane Targeting by the Flagellar Calcium-binding Protein (FCaBP), a Myristoylated and Palmitoylated Calcium Sensor in Trypanosoma cruzi*

A. Fisher, H. Robinson, K. T. Buchanan, 2008, Journal of Biological Chemistry.

A novel flagellar Ca2+-binding protein in trypanosomes.

K. Krause, J. Donelson, K. Kim, 1989, The Journal of biological chemistry.

83‐Kilodalton heat shock proteins of trypanosomes are potent peptide‐stimulated ATPases

C. Walsh, D. Engman, M. Bradley, 1992, Protein science : a publication of the Protein Society.

Responsive microtubule dynamics promote cell invasion by Trypanosoma cruzi

Derek A. Applewhite, D. Engman, G. W. G. Luxton, 2005, Cellular microbiology.

MANGANESE deficiency.

E. Zackai, G. Reifenberger, T. Dierks, 2022, Journal of the American Veterinary Medical Association.

Ubiquitin genes in trypanosomatidae.

J. Donelson, K. Kim, D. Engman, 1988, The Journal of biological chemistry.

Human humoral immunity to hsp70 during Trypanosoma cruzi infection.

J. Donelson, D. Engman, E. Dragon, 1990, Journal of immunology.

A novel reiterated family of transcribed oligo(A)-terminated, interspersed DNA elements in the genome of Trypanosoma cruzi.

R. Mortara, D. Engman, J. F. da Silveira, 2003, Memorias do Instituto Oswaldo Cruz.

Cell Cycle Inhibition To Treat Sleeping Sickness

C. Olson, C. Epting, D. Engman, 2017, mBio.

1H, 15N, and 13C chemical shift assignments of the calflagin Tb24 flagellar calcium binding protein of Trypanosoma brucei

Xianzhong Xu, C. Olson, D. Engman, 2013, Biomolecular NMR assignments.

Maternal uniparental disomy for chromosome 14.

E. Zackai, G. Reifenberger, T. Dierks, 1991, Journal of medical genetics.

Mesangiocapillary glomerulonephritis.

E. Zackai, I. Harting, B. McGuinness, 1992, Journal of the American Society of Nephrology : JASN.

Enhanced Efferocytosis of Apoptotic Cardiomyocytes Through Myeloid-Epithelial-Reproductive Tyrosine Kinase Links Acute Inflammation Resolution to Cardiac Repair After Infarction

S. Homma, S. Miller, D. Vaughan, 2013, Circulation research.

Recombinant cardiac myosin fragment induces experimental autoimmune myocarditis via activation of Th1 and Th17 immunity

D. Engman, M. Daniels, Kegiang Wang, 2008, Autoimmunity.

Molecular Determinants of Ciliary Membrane Localization of Trypanosoma cruzi Flagellar Calcium-binding Protein*

Danijela Maric, B. McGwire, K. T. Buchanan, 2011, The Journal of Biological Chemistry.

Comparison of angiotensin converting enzyme inhibition and angiotensin II receptor blockade for the prevention of experimental autoimmune myocarditis.

D. Engman, M. Daniels, Thomas J Bahk, 2008, International journal of cardiology.

Micronutrient Deficiencies

T. Dierks, I. Harting, J. Hellemans, 2010 .

Sphingolipid synthesis is necessary for kinetoplast segregation and cytokinesis in Trypanosoma brucei

C. Olson, D. Engman, I. Almeida, 2008, Journal of Cell Science.