J. Rothnagel

发表

Green fluorescent protein as a reporter in translational assays.

Xue-Qing Wang, T. Hadwen, J. Rothnagel, 2005, Analytical biochemistry.

Emerging evidence for functional peptides encoded by short open reading frames

Joseph A. Rothnagel, Shea J. Andrews, S. Andrews, 2014, Nature Reviews Genetics.

Evidence for conservation and selection of upstream open reading frames suggests probable encoding of bioactive peptides

Mark L Crowe, M. Crowe, Xue-Qing Wang, 2006, BMC Genomics.

Emerging evidence for functional peptides encoded by short open reading frames

Joseph A. Rothnagel, Shea J. Andrews, S. Andrews, 2014, Nature Reviews Genetics.

Downstream targets of heterogeneous nuclear ribonucleoprotein A2 mediate cell proliferation

P. Leedman, Michael R. Epis, J. Rothnagel, 2009, Molecular carcinogenesis.

Abnormal keratin 1 and 10 cytoskeleton in cultured keratinocytes from epidermolytic hyperkeratosis caused by keratin 10 mutations.

C. Scaletta, D. Hohl, D. Roop, 1994, The Journal of investigative dermatology.

An asparagine to threonine substitution in the 1A domain of keratin 1: a novel mutation that causes epidermolytic hyperkeratosis

D. Hohl, D. Roop, M. Huber, 1999, Experimental dermatology.

Advances in Brief Cooperation between \-fos and v-rasHAInduces Autonomous Papillomas in Transgenic Epidermis but not Malignant Conversion 1

Joshua, D. Roop, J. Rothnagel, 2006 .

Identification of a calcium-inducible, epidermal-specific regulatory element in the 3'-flanking region of the human keratin 1 gene.

D. Roop, J. Rothnagel, D. Greenhalgh, 1993, The Journal of investigative dermatology.

Sequential Changes in Gene Expression during Epidermal Differentiation

P. Steinert, D. Roop, H. Nakazawa, 1988 .

Alternatively Spliced Products of the Human Kinesin Light Chain 1 (KNS2) Gene

J. Rothnagel, D. Mahony, A. McCart, 2003, Traffic.

Targeting expression of a dominant-negative retinoic acid receptor mutant in the epidermis of transgenic mice results in loss of barrier function.

J. Rothnagel, S. Imakado, J. Gordon, 1995, Genes & development.

Loricrin expression is coordinated with other epidermal proteins and the appearance of lipid lamellar granules in development.

D. Roop, J. Rothnagel, J. Greer, 1995, The Journal of investigative dermatology.

Inhibition of skin development by overexpression of transforming growth factor beta 1 in the epidermis of transgenic mice.

A. Roberts, N. Roche, D. Roop, 1993, Proceedings of the National Academy of Sciences of the United States of America.

L1PA2 transposons contribute abundant regulatory sequences in MCF7 breast cancer cell line

J. Rothnagel, K. Upton, Jiayue Jiang, 2020, bioRxiv.

Letters to the editor: identification of polymorphic variants of the GLI1 oncogene.

J. Rothnagel, X. Wang, N. Chan, 2000, The Journal of investigative dermatology.

The Mallory body as an aggresome: in vitro studies.

C. Swagell, J. Rothnagel, S. French, 2002, Experimental and molecular pathology.

Mutations in the 1A domain of keratin 9 in patients with epidermolytic palmoplantar keratoderma.

D. Hohl, D. Roop, M. Huber, 1995, The Journal of investigative dermatology.

Characterization of the mouse loricrin gene: linkage with profilaggrin and the flaky tail and soft coat mutant loci on chromosome 3.

S. Naylor, N. Copeland, D. Gilbert, 1994, Genomics.

Mutations in the Rod Domains of Keratins 1 and 10 in Epidermolytic Hyperkeratosis

D Hohl, D. Hohl, D. Roop, 1992, Science.

Identification of a novel mutation in keratin 1 in a family with epidermolytic hyperkeratosis

D. Roop, J. Rothnagel, E. Epstein, 2000, Experimental dermatology.

A novel substitution in keratin 10 in epidermolytic hyperkeratosis.

D. Hohl, D. Roop, M. Huber, 1999, The Journal of investigative dermatology.

A novel dinucleotide mutation in keratin 10 in the annular epidermolytic ichthyosis variant of bullous congenital ichthyosiform erythroderma.

D. Hohl, D. Roop, M. Huber, 1997, The Journal of investigative dermatology.

Mutations in the rod domain of keratin 2e in patients with ichthyosis bullosa of Siemens

D. Hohl, D. Roop, M. Pittelkow, 1994, Nature Genetics.

Genetic disorders of keratin: are scarring alopecias a sub-set?

D. Roop, J. Rothnagel, M. Longley, 1994, Journal of dermatological science.

Prenatal diagnosis of epidermolytic hyperkeratosis by direct gene sequencing.

D. Roop, J. Rothnagel, M. Longley, 1994, The Journal of investigative dermatology.

A mutational hot spot in keratin 10 (KRT 10) in patients with epidermolytic hyperkeratosis.

D. Hohl, D. Roop, M. Pittelkow, 1993, Human molecular genetics.

Mutation of a type II keratin gene (K6a) in pachyonychia congenita

J. Rothnagel, A. Kansky, R. J. Turner, 1995, Nature Genetics.

Roles of heterogeneous nuclear ribonucleoproteins A and B in cell proliferation

Melissa A. Brown, J. Rothnagel, N. Saunders, 2005, Journal of Cell Science.

Characterization of the mouse hnRNP A2/B1/B0 gene and identification of processed pseudogenes.

J. Rothnagel, Ross Smith, J. Hatfield, 2002, Gene.

Citrulline in proteins from the enzymatic deimination of arginine residues.

J. Rothnagel, G. Rogers, 1984, Methods in Enzymology.

Arginine Methylation of hnRNP A2 Does Not Directly Govern Its Subcellular Localization

J. Rothnagel, Ying Wei, A. Nouwens, 2013, PloS one.

A novel mutation in the 1A domain of keratin 2e in ichthyosis bullosa of Siemens.

L. Goldsmith, D. Roop, J. Rothnagel, 1999, The Journal of investigative dermatology.

A novel mutation in the L12 domain of keratin 5 in the Köbner variant of epidermolysis bullosa simplex.

J. Rothnagel, P. Listwan, G. Siller, 1998, The Journal of investigative dermatology.

The structure of the gene for mouse filaggrin and a comparison of the repeating units.

P. Steinert, J. Rothnagel, 1990, The Journal of biological chemistry.

Enzymatic Recognition of 2′‐Modified Ribonucleoside 5′‐Triphosphates: Towards the Evolution of Versatile Aptamers

J. Rothnagel, R. Veedu, R. N. Veedu, 2012, Chembiochem : a European journal of chemical biology.

Complex Evolutionary Relationships Among Four Classes of Modular RNA-Binding Splicing Regulators in Eukaryotes: The hnRNP, SR, ELAV-Like and CELF Proteins

K. Kassahn, Adam Skarshewski, J. Rothnagel, 2012, Journal of Molecular Evolution.

Characterization of mouse profilaggrin: evidence for nuclear engulfment and translocation of the profilaggrin B-domain during epidermal differentiation.

J. Rothnagel, D. Mahony, S. Karunaratne, 2002, The Journal of investigative dermatology.

Keratin bundling proteins.

J. Rothnagel, P. Listwan, 2004, Methods in cell biology.

Fetuin-A: a major fetal serum protein that promotes "wound closure" and scarless healing.

J. Rothnagel, R. Kimble, N. Saunders, 2008, The Journal of investigative dermatology.

Ichthyosis bullosa and Bullous Congenital

P. Itin, J. Uitto, J. Benhattar, 2009 .

Profilaggrin and the fused S100 family of calcium-binding proteins

J. Rothnagel, R. Presland, O. Lawrence, 2005 .

Regulation of MAPK activation, AP-1 transcription factor expression and keratinocyte differentiation in wounded fetal skin.

J. Rothnagel, A. Cowin, A. Varelias, 2004, The Journal of investigative dermatology.

Targeted overexpression of transforming growth factor alpha in the epidermis of transgenic mice elicits hyperplasia, hyperkeratosis, and spontaneous, squamous papillomas.

D. Roop, J. Rothnagel, L. Nanney, 1993, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Isolation (from a basal cell carcinoma) of a functionally distinct fibroblast-like cell type that overexpresses Ptch.

J. Rothnagel, N. Saunders, A. Dahler, 2002, The Journal of investigative dermatology.

Identification and characterisation of sPEPs in Cryptococcus neoformans.

Toan K. Phung, J. Fraser, J. Rothnagel, 2022, Fungal genetics and biology : FG & B.

uPEPperoni: An online tool for upstream open reading frame location and analysis of transcript conservation

Ross Smith, Thomas Huber, Scott A. Beatson, 2014, BMC Bioinformatics.

Differential subnuclear localisation of hnRNPs A/B is dependent on transcription and cell cycle stage.

J. Rothnagel, Ross Smith, L. Friend, 2008, Biochimica et biophysica acta.

Trichohyalin, an intermediate filament-associated protein of the hair follicle

J. Rothnagel, G. Rogers, 1986, The Journal of cell biology.

Short Open Reading Frames and Their Encoded Peptides

G. Menschaert, J. Rothnagel, 2018, Proteomics.

Identification and functional analysis of novel BRCA1 transcripts, including mouse Brca1-Iris and human pseudo-BRCA1

A. Spurdle, S. Edwards, J. French, 2008, Breast Cancer Research and Treatment.

Cooperation between v-fos and v-rasHA induces autonomous papillomas in transgenic epidermis but not malignant conversion.

D. Roop, J. Rothnagel, D. Greenhalgh, 1993, Cancer research.

Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v‐Ha‐ras oncogene

D. Roop, J. Rothnagel, D. Greenhalgh, 1993, Molecular carcinogenesis.

Epidermal expression of transforming growth factor‐α in transgenic mice: Induction of spontaneous and 12‐O‐tetradecanoylphorbol‐13‐acetate‐induced papillomas via a mechanism independent of Ha‐ras activation or overexpression

D. Roop, J. Rothnagel, D. Greenhalgh, 1994, Molecular carcinogenesis.

Integrated transcription factor profiling with transcriptome analysis identifies L1PA2 transposons as global regulatory modulators in a breast cancer model

J. Rothnagel, K. Upton, Jiayue Jiang, 2021, Scientific Reports.

Epidermis: an attractive target tissue for gene therapy.

D. Roop, J. Rothnagel, D. Greenhalgh, 1994, The Journal of investigative dermatology.

Transgenic models of skin diseases.

D. Roop, J. Rothnagel, D. Greenhalgh, 1993, Archives of dermatology.

Identification of a major keratinocyte cell envelope protein, loricrin

A. Steven, D. Hohl, P. Steinert, 1990, Cell.

The companion layer and outer root sheath of the anagen hair follicle.

J. Rothnagel, D. Mahony, S. Karunaratne, 1999, Experimental dermatology.

Hair follicle companion layer: reacquainting an old friend.

D. Roop, J. Rothnagel, 1995, The Journal of investigative dermatology.

Trans glutaminase-mediated cross-linking in mammalian epidermis

J. Rothnagel, G. Rogers, 2004, Molecular and Cellular Biochemistry.

Widespread Exaptation of L1 Transposons for Transcription Factor Binding in Breast Cancer

J. Rothnagel, K. Upton, Jiayue Jiang, 2021, International journal of molecular sciences.

Analysis of mouse keratin 6a regulatory sequences in transgenic mice reveals constitutive, tissue-specific expression by a keratin 6a minigene.

G. Cam, J. Rothnagel, D. Mahony, 2000, The Journal of investigative dermatology.

The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis.

D. Roop, J. Rothnagel, M. Longley, 1999, Differentiation; research in biological diversity.

Expression of MK6a dominant-negative and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle.

D. Roop, J. Rothnagel, L. Petherbridge, 1999, Differentiation; research in biological diversity.

A transgenic mouse model that recapitulates the clinical features of both neonatal and adult forms of the skin disease epidermolytic hyperkeratosis.

D. Roop, J. Rothnagel, M. Longley, 1996, Differentiation; research in biological diversity.

Transgenic mice expressing targeted HPV-18 E6 and E7 oncogenes in the epidermis develop verrucous lesions and spontaneous, rasHa-activated papillomas.

R. Schlegel, D. Roop, J. Rothnagel, 1994, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Targeting gene expression to the epidermis of transgenic mice: potential applications to genetic skin disorders.

D. Roop, J. Rothnagel, D. Greenhalgh, 1990, The Journal of investigative dermatology.

Functional implications of the emergence of alternative splicing in hnRNP A/B transcripts.

M. Ragan, K. Kassahn, Adam Skarshewski, 2010, RNA.

RNA Decay and RNA Silencing in Plants: Competition or Collaboration?

J. Rothnagel, B. Carroll, C. Brosnan, 2011, Front. Plant Sci..

Post-transcriptional Regulation of the GLI1 Oncogene by the Expression of Alternative 5′ Untranslated Regions*

Xue-Qing Wang, J. Rothnagel, X. Wang, 2001, The Journal of Biological Chemistry.

The Proximal Promoter of the Mouse Loricrin Gene Contains a Functional AP-1 Element and Directs Keratinocyte-specific but Not Differentiation-specific Expression (*)

D. Roop, J. Rothnagel, D. Disepio, 1995, The Journal of Biological Chemistry.

Hyperplasia, hyperkeratosis and benign tumor production in transgenic mice by a targeted v-fos oncogene suggest a role for fos in epidermal differentiation and neoplasia.

C. Fisher, D. Roop, J. Rothnagel, 1993, Oncogene.

Characterization of loricrin regulation in vitro and in transgenic mice.

D. Roop, J. Rothnagel, D. Disepio, 1999, Differentiation; research in biological diversity.

Overexpression of Sonic Hedgehog suppresses embryonic hair follicle morphogenesis.

J. Bowles, B. Wainwright, J. Rothnagel, 2003, Developmental biology.

Targeted disruption of Brca1 in restricted compartments of the mouse mammary epithelia

S. Lakhani, J. French, C. Smart, 2008, Breast Cancer Research and Treatment.

Complex Evolutionary Relationships Among Four Classes of Modular RNA-Binding Splicing Regulators in Eukaryotes: The hnRNP, SR, ELAV-Like and CELF Proteins

K. Kassahn, Adam Skarshewski, J. Rothnagel, 2012, Journal of Molecular Evolution.

5'-untranslated regions with multiple upstream AUG codons can support low-level translation via leaky scanning and reinitiation.

Xue-Qing Wang, J. Rothnagel, 2004, Nucleic acids research.

Characterization of mouse Frizzled-3 expression in hair follicle development and identification of the human homolog in keratinocytes.

G. Cam, Xue-Qing Wang, J. Rothnagel, 2001, The Journal of investigative dermatology.

The gene for mouse epidermal filaggrin precursor. Its partial characterization, expression, and sequence of a repeating filaggrin unit.

P M Steinert, W. Idler, P. Steinert, 1987, The Journal of biological chemistry.

Differentiation-specific expression of human keratin 1 is mediated by a composite AP-1/steroid hormone element.

S. Tsai, D. Roop, J. Rothnagel, 1994, The Journal of biological chemistry.

CFTR mRNA expression is regulated by an upstream open reading frame and RNA secondary structure in its 5' untranslated region.

S. Lukowski, A. E. Trezíse, J. Rothnagel, 2015, Human molecular genetics.

Improved detection of lacZ reporter gene expression in transgenic epithelia by immunofluorescence microscopy

J. Rothnagel, D. Mahony, S. Karunaratne, 2002, Experimental dermatology.

A minimal 120 bp promoter is sufficient for sustained, tissue-specific expression of Keratin k6A in transgenic mice

J. Rothnagel, D. Mahony, S. Karunaratne, 1999 .

Development of transgenic mouse models of skin carcinogenesis: potential applications.

D. Roop, J. Rothnagel, D. Greenhalgh, 1994, Progress in clinical and biological research.

Differential Subcellular Distributions and Trafficking Functions of hnRNP A2/B1 Spliceoforms

G. Korza, J. Carson, J. Rothnagel, 2010, Traffic.

Retinoic acid suppression of loricrin expression in reconstituted human skin cultured at the liquid-air interface.

D. Roop, J. Rothnagel, L. Brown, 1994, The Journal of investigative dermatology.

Frizzled-3a and slit2 genetically interact to modulate midline axon crossing in the telencephalon

J. Rothnagel, B. Key, W. Hofmeister, 2012, Mechanisms of Development.

Krt6a-Cre transgenic mice direct LoxP-mediated recombination to the companion cell layer of the hair follicle and following induction by retinoic acid to the interfollicular epidermis.

B. Wainwright, J. Rothnagel, C. Wicking, 2004, The Journal of investigative dermatology.

Roles of heterogeneous nuclear ribonucleoproteins A and B in cell proliferation

Melissa A. Brown, J. Rothnagel, N. Saunders, 2005, Journal of Cell Science.

Evidence for conservation and selection of upstream open reading frames suggests probable encoding of bioactive peptides

M. Crowe, Xue-Qing Wang, J. Rothnagel, 2006, BMC Genomics.

Characterisation of the mouse HNRNP A2/B1/B0 gene and identification of processed pseudogenes

J. Rothnagel, Ross Smith, J. Hatfield, 2002 .

Functional implications of the emergence of alternative splicing in hnRNP A/B transcripts.

M. Ragan, Adam Skarshewski, J. Rothnagel, 2010, RNA.