D. Stephens

发表

Intracellular trafficking pathways and drug delivery: fluorescence imaging of living and fixed cells.

A. Jones, P. Watson, D. Stephens, 2005, Advanced drug delivery reviews.

Specificity of cytoplasmic dynein subunits in discrete membrane-trafficking steps.

D. Stephens, K. Palmer, H. Hughes, 2009, Molecular biology of the cell.

TFG Promotes Organization of Transitional ER and Efficient Collagen Secretion

D. Stephens, K. Heesom, Janine McCaughey, 2016, Cell reports.

The Retromer Coat Complex Coordinates Endosomal Sorting and Dynein-Mediated Transport, with Carrier Recognition by the trans-Golgi Network

H. Korswagen, T. Wassmer, P. Verkade, 2009, Developmental cell.

Phosphatidylinositol 4-kinase is required for endosomal trafficking and degradation of the EGF receptor

J. Hsuan, D. Stephens, S. Minogue, 2006, Journal of Cell Science.

The many ways to cross the plasma membrane

R Pepperkok, D J Stephens, R. Pepperkok, 2001, Proceedings of the National Academy of Sciences of the United States of America.

The Golgi matrix protein giantin is required for normal cilia function in zebrafish

D. Stephens, N. Stevenson, D. Bergen, 2017, bioRxiv.

Organisation of human ER-exit sites: requirements for the localisation of Sec16 to transitional ER

Judith M. Mantell, P. Verkade, P. Watson, 2009, Journal of Cell Science.

ER exit sites – Localization and control of COPII vesicle formation

D. Stephens, A. Budnik, 2009, FEBS letters.

Early stages of retinal development depend on Sec13 function

D. Stephens, Katy Schmidt, Yi Feng, 2013, Biology Open.

ER-to-Golgi transport: form and formation of vesicular and tubular carriers.

P. Watson, D. Stephens, 2005, Biochimica et biophysica acta.

Nordihydroguaiaretic Acid Affects Multiple Dynein-Dynactin Functions in Interphase and Mitotic Cells

M. Tagaya, D. Stephens, T. Yoshimori, 2007, Molecular Pharmacology.

Metabolites of the β‐amyloid precursor protein generated by β‐secretase localise to the trans‐golgi network and late endosome in 293 cells

B. Austen, D. Stephens, D. Stephens, 1996 .

A role for endoplasmic reticulum exit sites in foot-and-mouth disease virus infection

Daniel J. Fullen, D. Stephens, Katy Moffat, 2013, The Journal of general virology.

Insulin promotes Rip11 accumulation at the plasma membrane by inhibiting a dynamin- and PI3-kinase-dependent, but Akt-independent, internalisation event

J. Tavaré, D. Stephens, Lorna Hodgson, 2016, Cellular signalling.

ER-to-Golgi trafficking of procollagen in the absence of large carriers

D. Stephens, Janine McCaughey, N. Stevenson, 2018, bioRxiv.

Efficient coupling of Sec23-Sec24 to Sec13-Sec31 drives COPII-dependent collagen secretion and is essential for normal craniofacial development

P. Verkade, D. Stephens, Katy Schmidt, 2008, Journal of Cell Science.

Characteristic phenotypes associated with congenital dyserythropoietic anemia (type II) manifest at different stages of erythropoiesis

D. Stephens, A. Toye, A. Budnik, 2013, Haematologica.

A role for Tctex-1 (DYNLT1) in controlling primary cilium length.

D. Stephens, K. Palmer, N. Smyllie, 2011, European journal of cell biology.

Epithelial organization and cyst lumen expansion require efficient Sec13–Sec31-driven secretion

D. Stephens, Lorna Hodgson, Katy Schmidt, 2012, Journal of Cell Science.

Planar Cell Polarity Effector Proteins Inturned and Fuzzy Form a Rab23 GEF Complex

H. Strutt, D. Strutt, D. Stephens, 2019, Current Biology.

Cytoplasmic dynein-2 at a glance

D. Stephens, N. Stevenson, A. Roberts, 2020, Journal of Cell Science.

Subunit composition of the human cytoplasmic dynein-2 complex

D. Stephens, N. Stevenson, D. Asante, 2014, Journal of Cell Science.

A role for the Golgi matrix protein giantin in ciliogenesis through control of the localization of dynein-2

D. Stephens, K. Palmer, C. Westlake, 2013, Journal of Cell Science.

Differential effects of a GTP-restricted mutant of Sar1p on segregation of cargo during export from the endoplasmic reticulum

R. Pepperkok, D. Stephens, 2004, Journal of Cell Science.

The intracellular transport of chylomicrons requires the small GTPase, Sar1b

C. Shoulders, D. Stephens, Bethan S. Jones, 2004, Current opinion in lipidology.

Specific Functions of BIG1 and BIG2 in Endomembrane Organization

D. Stephens, F. Boal, 2010, PloS one.

The secretion inhibitor Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network

L. Johannes, G. Clarkson, P. Watson, 2008, The Biochemical journal.

The secretion inhibitor Exo 2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network

L. Johannes, G. Clarkson, P. Watson, 2008 .

Imaging of procollagen transport reveals COPI-dependent cargo sorting during ER-to-Golgi transport in mammalian cells.

R. Pepperkok, D. Stephens, 2002, Journal of cell science.

Sec16A defines the site for vesicle budding from the endoplasmic reticulum on exit from mitosis

D. Stephens, H. Hughes, 2010, Journal of Cell Science.

Disease-associated mutations in WDR34 lead to diverse impacts on the assembly and function of dynein-2

D. Stephens, K. Nakayama, K. Heesom, 2022, bioRxiv.

Regulator of calcineurin-2 is a centriolar protein with a role in cilia length control

D. Stephens, Janine McCaughey, N. Stevenson, 2018, Journal of Cell Science.

Regulator of calcineurin-2 is a ciliary protein with a role in cilia length control

D. Stephens, Janine McCaughey, N. Stevenson, 2017, bioRxiv.

SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment

T. Wassmer, P. Cullen, D. Stephens, 2007, Nature Cell Biology.

Specificity of interaction between adaptor-complex medium chains and the tyrosine-based sorting motifs of TGN38 and lgp120.

G. Banting, D. Stephens, 1998, The Biochemical journal.

Characterization of human Sec16B: indications of specialized, non-redundant functions

D. Stephens, K. Heesom, A. Budnik, 2011, Scientific reports.

The biosynthesis of membrane proteins

B. Austen, D. Stephens, S. Kulkarni, 1995 .

Assembly of Membrane Proteins and their Movement to the Cell Surface

B. Austen, D. Stephens, S. Kulkarni, 1994 .

Kinesin‐1 (uKHC/KIF5B) is Required for Bidirectional Motility of ER Exit Sites and Efficient ER‐to‐Golgi Transport

Vijay R. Gupta, D. Stephens, K. Palmer, 2008, Traffic.

Insulin dependent tyrosine phosphorylation of the tyrosine internalisation motif of TGN38 creates a specific SH2 domain binding site

G. Banting, D. Stephens, 1997, FEBS letters.

Cargo loading at the ER

D. Stephens, Katy Schmidt, 2010, Molecular membrane biology.

Membrane contact sites—an interesting species, an interesting mix

D. Stephens, Victoria J. Miller, 2013, EMBO reports.

Assembly, Secretory Pathway Trafficking, and Surface Delivery of Kainate Receptors Is Regulated by Neuronal Activity

J. Henley, K. Wilkinson, D. Stephens, 2017, Cell reports.

Role of adaptor complex AP-3 in targeting wild-type and mutated CD63 to lysosomes.

Barbara J. Reaves, J. Briggs, J. Luzio, 2002, Molecular biology of the cell.

LG186: An Inhibitor of GBF1 Function that Causes Golgi Disassembly in Human and Canine Cells

J. Cherfils, R. Sessions, M. Zeghouf, 2010, Traffic.

Analysis of GTPase-activating proteins: Rab1 and Rab43 are key Rabs required to maintain a functional Golgi complex in human cells

C. Preisinger, D. Stephens, F. Barr, 2007, Journal of Cell Science.

PCTAIRE protein kinases interact directly with the COPII complex and modulate secretory cargo transport

D. Stephens, K. Palmer, J. Konkel, 2005, Journal of Cell Science.

Artificially Inducing Close Apposition of Endoplasmic Reticulum and Mitochondria Induces Mitochondrial Fragmentation

D. Stephens, Victoria J. Miller, 2014, bioRxiv.

RNA interference approaches to examine Golgi function in animal cell culture.

C. McKinnon, D. Stephens, H. Mellor, 2013, Methods in cell biology.

COPII-dependent ER export in animal cells: adaptation and control for diverse cargo

D. Stephens, Janine McCaughey, 2018, Histochemistry and Cell Biology.

Assembly, organization, and function of the COPII coat

David J. Stephens, D. Stephens, H. Hughes, 2007, Histochemistry and Cell Biology.

Light Microscopy Techniques for Live Cell Imaging

Victoria J Allan, David J Stephens, D. Stephens, 2003, Science.

The Endoplasmic Reticulum Coat Protein II Transport Machinery Coordinates Cellular Lipid Secretion and Cholesterol Biosynthesis*

M. Nieuwdorp, C. Shoulders, L. Fryer, 2013, The Journal of Biological Chemistry.

Sec16 Defines Endoplasmic Reticulum Exit Sites and is Required for Secretory Cargo Export in Mammalian Cells

David J Stephens, P. Watson, D. Stephens, 2006, Traffic.

ER-to-Golgi Transport: A Sizeable Problem.

D. Stephens, Janine McCaughey, 2019, Trends in cell biology.

P4HB recurrent missense mutation causing Cole-Carpenter syndrome

A. Offiah, N. Bishop, B. Wagner, 2017, Journal of Medical Genetics.

Microtubule plus-end loading of p150Glued is mediated by EB1 and CLIP-170 but is not required for intracellular membrane traffic in mammalian cells

P. Watson, D. Stephens, 2006, Journal of Cell Science.

Coupling of ER exit to microtubules through direct interaction of COPII with dynactin

Rainer Pepperkok, David J. Stephens, R. Pepperkok, 2005, Nature Cell Biology.

The Golgi matrix protein giantin is required for normal cilia function in zebrafish

D. Stephens, N. Stevenson, D. Bergen, 2017, Biology Open.

De novo formation, fusion and fission of mammalian COPII‐coated endoplasmic reticulum exit sites

D. Stephens, 2003, EMBO reports.

COPI-coated ER-to-Golgi transport complexes segregate from COPII in close proximity to ER exit sites.

R Pepperkok, D J Stephens, R. Pepperkok, 2000, Journal of cell science.

Vesicle coating and uncoating: controlling the formation of large COPII-coated carriers

D. Stephens, Anna K. Townley, 2009, F1000 biology reports.

Giantin is required for intracellular N-terminal processing of type I procollagen

K. Kadler, D. Stephens, N. Stevenson, 2020, bioRxiv.

Microtubule motors mediate endosomal sorting by maintaining functional domain organization

P. Cullen, D. Stephens, Anna K. Townley, 2013, Journal of Cell Science.

A role for glycogen synthase kinase-3 in mitotic spindle dynamics and chromosome alignment

J. Tavaré, D. Stephens, J. Wakefield, 2003, Journal of Cell Science.

Lumenal targeted GFP, used as a marker of soluble cargo, visualises rapid ERGIC to Golgi traffic by a tubulo-vesicular network.

D. Stephens, I. Schulz, R. Blum, 2000, Journal of cell science.

Giantin-knockout models reveal a feedback loop between Golgi function and glycosyltransferase expression

D. Stephens, N. Stevenson, D. Bergen, 2017, Journal of Cell Science.

The role of cholesterol in the biosynthesis of beta-amyloid.

D J Stephens, B. Austen, D. Stephens, 1999, Neuroreport.

Bap31 is an itinerant protein that moves between the peripheral endoplasmic reticulum (ER) and a juxtanuclear compartment related to ER-associated Degradation.

David J Stephens, H. Hauri, M. Tagaya, 2008, Molecular biology of the cell.

The role of motor proteins in endosomal sorting.

D. Stephens, Sylvie D. Hunt, 2011, Biochemical Society transactions.

Secretory Cargo Regulates the Turnover of COPII Subunits at Single ER Exit Sites

R. Pepperkok, T. Zimmermann, M. Weiss, 2006, Current Biology.

Immunofluorescent labeling and fluorescent dyes

P. Watson, D. Stephens, K. Palmer, 2005 .

Cep126 is required for pericentriolar satellite localisation to the centrosome and for primary cilium formation

A. Luini, A. Colanzi, D. Stephens, 2014, Biology of the cell.

A general role for TANGO1, encoded by MIA3, in secretory pathway organization and function

D. Stephens, K. Heesom, Janine McCaughey, 2021, bioRxiv.

Functional coupling of microtubules to membranes – implications for membrane structure and dynamics

D. Stephens, 2012, Journal of Cell Science.

Measuring the induction or inhibition of apoptosis by HPV proteins.

A. Kowalczyk, G. Roeder, K. Gaston, 2005, Methods in molecular medicine.

Supply chain logistics – the role of the Golgi complex in extracellular matrix production and maintenance

D. Stephens, N. Stevenson, M. Lowe, 2022, Journal of cell science.

Direct Interaction of the trans-Golgi Network Membrane Protein, TGN38, with the F-actin Binding Protein, Neurabin*

G. Banting, D. Stephens, George Banting, 1999, The Journal of Biological Chemistry.

Fine tuning Exo2, a small molecule inhibitor of secretion and retrograde trafficking pathways in mammalian cells.

G. Clarkson, D. Stephens, R. Spooner, 2010, Molecular bioSystems.

The Use of Yeast Two‐Hybrid Screens in Studies of Protein:Protein Interactions Involved in Trafficking

D J Stephens, G. Banting, D. Stephens, 2000, Traffic.

Inhibition of the Interaction between Tyrosine-based Motifs and the Medium Chain Subunit of the AP-2 Adaptor Complex by Specific Tyrphostins*

G. Banting, D. Stephens, C. Crump, 1998, The Journal of Biological Chemistry.

In vivo dynamics of the F-actin-binding protein neurabin-II.

G. Banting, D. Stephens, 2000, The Biochemical journal.

Giantin knockout models reveal a feedback loop between Golgi function and glycosyltransferase expression

D. Stephens, N. Stevenson, D. Bergen, 2017, bioRxiv.

Giantin Knockout Models Reveal The Capacity Of The Golgi To Regulate Its Biochemistry By Controlling Glycosyltransferase Expression

D. Stephens, N. Stevenson, D. Bergen, 2017 .

Dynein-2 intermediate chains play crucial but distinct roles in primary cilia formation and function

D. Stephens, K. Heesom, N. Stevenson, 2018, bioRxiv.

Dynein-2 is required for a functional transition zone and bidirectional ciliary trafficking

D. Stephens, K. Heesom, N. Stevenson, 2018 .

The role of microtubules in transport between the endoplasmic reticulum and Golgi apparatus in mammalian cells.

P. Watson, D. Stephens, K. Palmer, 2005, Biochemical Society symposium.

Biogenesis of ER-to-Golgi transport carriers: complex roles of COPII in ER export.

D. Stephens, K. Palmer, 2004, Trends in cell biology.

Illuminating the secretory pathway: when do we need vesicles?

R. Pepperkok, D. Stephens, 2001, Journal of cell science.

MITOCHONDRIA INDUCES MITOCHONDRIAL FRAGMENTATION.

D. Stephens, Victoria J. Miller, 2014 .

Cell biology: Collagen secretion explained

D. Stephens, 2012, Nature.

Bap 31 Is an Itinerant Protein that Moves between the Peripheral ER and a Juxtanuclear Compartment Related to ER-associated Degradation

David J. Stephens, H. Hauri, M. Tagaya, 2008 .

Serine 331 and Tyrosine 333 Are Both Involved in the Interaction between the Cytosolic Domain of TGN38 and the μ2 Subunit of the AP2 Clathrin Adaptor Complex*

A. Clarke, G. Banting, D. Stephens, 1997, The Journal of Biological Chemistry.

MIA 3 / TANGO 1 enables efficient secretion by constraining COPII vesicle budding

D. Stephens, K. Heesom, Janine McCaughey, 2021 .

Biochemical Society Symposium

P. Booth, P. Curnow, M. Lorch, 2005 .

COPII-dependent ER export in animal cells: adaptation and control for diverse cargo

D. Stephens, Janine McCaughey, 2018, Histochemistry and Cell Biology.

Opposing microtubule motors control motility, morphology and cargo segregation during ER-to-Golgi transport

D. Stephens, Anna K. Brown, Sylvie D. Hunt, 2014, Biology Open.

Opposing Microtubule Motors Control Motility, Morphology, and Cargo Segregation During ER-to-Golgi Transport

D. Stephens, Anna K. Brown, Sylvie D. Hunt, 2014, bioRxiv.

Illuminating cellular structure and function in the early secretory pathway by multispectral 3D imaging in living cells

Rainer Pepperkok, Jeremy C. Simpson, David T. Shima, 2000, Photonics West - Biomedical Optics.

Developing pathways to clarify pathogenicity of unclassified variants in Osteogenesis Imperfecta genetic analysis

D. Stephens, Janine McCaughey, E. Hobson, 2019, Molecular genetics & genomic medicine.

(2011). A role for Tctex-1 (DYNLT1) in controlling primary cilium length. European Cell (10), 865 - 871.

D. Stephens, K. Palmer, N. Smyllie, 2011 .

Cleavage of a beta-amyloid precursor sequence by cathepsin D.

B. Austen, D. Stephens, 1995, Biomedical peptides, proteins & nucleic acids : structure, synthesis & biological activity.

Giantin knockout models reveal the capacity of the 1 Golgi to regulate its biochemistry 2 by controlling glycosyltransferase expression 3

D. Stephens, N. Stevenson, D. Bergen, 2017 .

Giantin knockout models reveal a feedback loop 1 between Golgi function and glycosyltransferase 2 expression 3 4

D. Stephens, N. Stevenson, D. Bergen, 2017 .

LG186: An Inhibitor of GBF1 Function that Causes Golgi Disassembly in Human and Canine Cells

J. Cherfils, R. Sessions, M. Zeghouf, 2010, Traffic.

Cargo loading at the ER

D. Stephens, Katy Schmidt, 2010, Molecular membrane biology.

The role of motor proteins in endosomal sorting.

D. Stephens, Sylvie D. Hunt, 2011, Biochemical Society transactions.

Insulin promotes Rip11 accumulation at the plasma membrane by inhibiting a dynamin- and PI3-kinase-dependent, but Akt-independent, internalisation event

J. Tavaré, D. Stephens, M. Mccaffrey, 2016, Cellular signalling.

Coming out of the dark: the evolving role of fluorescence imaging in drug delivery research.

Mark Gumbleton, David J Stephens, M. Gumbleton, 2005, Advanced drug delivery reviews.

Opposing microtubule motors control motility, morphology and cargo segregation during ER-to-Golgi transport

D. Stephens, Anna K. Brown, Sylvie D. Hunt, 2014, Biology Open.

Kinesin‐1 (uKHC/KIF5B) is Required for Bidirectional Motility of ER Exit Sites and Efficient ER‐to‐Golgi Transport

D. Stephens, K. Palmer, A. Hudson, 2008, Traffic.

Optimising the precision for localising fluorescent proteins in living cells by 2D Gaussian fitting of digital images: application to COPII-coated endoplasmic reticulum exit sites

D. Stephens, A. Hudson, P. Spence, 2008, European Biophysics Journal.