J. Gies

发表

Construction of a plasmid containing human SMN, the SMA determining gene, coupled to EGFP.

A. Arnold, M. Guèye, P. Rondé, 2002, Plasmid.

Comparing reagents for efficient transfection of human primary myoblasts: FuGENE 6, Effectene and ExGen 500

A. Arnold, P. Poindron, J. Gies, 2006, Fundamental & clinical pharmacology.

Antibacterial textiles functionalized by layer-by-layer assembly of polyelectrolytes and TiO2 photocatalyst

N. Keller, J. Gies, G. Carré, 2015 .

Drugs and their molecular targets: an updated overview

J. Gies, Y. Landry, 2008, Fundamental & clinical pharmacology.

Sialic acid residues as catalysts for M2-muscarinic agonist-receptor interactions.

J. Gies, Y. Landry, E. Haddad, 1990, Molecular pharmacology.

Drugs interacting with G protein alpha subunits: selectivity and perspectives.

J. Gies, A. Chahdi, L. Daeffler, 1998, Fundamental & clinical pharmacology.

Heterotrimeric G proteins control diverse pathways of transmembrane signaling, a base for drug discovery.

J. Gies, Y. Landry, 2002, Mini reviews in medicinal chemistry.

Heptahelical and other G-protein-coupled receptors (GPCRs) signaling.

J. Gies, Y. Landry, N. Niederhoffer, 2006, Current medicinal chemistry.

Inverse agonist activity of pirenzepine at M2 muscarinic acetylcholine receptors

J. Gies, F. Schmidlin, L. Daeffler, 1999, British journal of pharmacology.

Activation of rat peritoneal mast cells by substance P and mastoparan.

C. Bronner, J. Gies, Y. Landry, 1989, The Journal of pharmacology and experimental therapeutics.

Amyloid β Peptides Trigger CD47-Dependent Mast Cell Secretory and Phagocytic Responses

J. Gies, G. Coupin, R. Levy, 2009, International journal of immunopathology and pharmacology.

Phagocytic functions of microglial cells in the central nervous system and their importance in two neurodegenerative diseases: multiple sclerosis and Alzheimer’s disease

A. Arnold, P. Poindron, J. Gies, 2006, Central European Journal of Biology.

Interleukin-1beta induces bradykinin B2 receptor gene expression through a prostanoid cyclic AMP-dependent pathway in human bronchial smooth muscle cells.

C. Bertrand, J. Gies, F. Schmidlin, 1998, Molecular pharmacology.

Activation of CD47 receptors causes proliferation of human astrocytoma but not normal astrocytes via an Akt‐dependent pathway

T. Deramaudt, K. Takeda, P. Rondé, 2011, Glia.

Anti-neoplastic agent thymoquinone induces degradation of α and β tubulin proteins in human cancer cells without affecting their level in normal human fibroblasts

T. Sharif, C. Auger, M. Alhosin, 2012, Investigational New Drugs.

Bombesin Receptor Subtypes: Characterization and Solubilization

J. Gies, A. Trifilieff, E. Haddad, 1993 .

Kinins and respiratory tract diseases.

J. Gies, A. Trifilieff, A. Da Silva, 1993, The European respiratory journal.

Improved Methods for Culturing Rat and Mouse Motor Neurons

P. Poindron, J. Gies, A. Appert-Collin, 2005 .

PLA2 phosphorylation and cyclooxygenase-2 induction, through p38 MAP kinase pathway, is involved in the IL-1β-induced bradykinin B2 receptor gene transcription

C. Bertrand, J. Gies, F. Schmidlin, 2000, Naunyn-Schmiedeberg's Archives of Pharmacology.

Bombesin-induced contractions of guinea pig lung strips are modulated by endogenous nitric oxide

J. Gies, E. Lach, Laurent Daefller, 1995, Naunyn-Schmiedeberg's Archives of Pharmacology.

Contractile effect of bombesin on guinea pig lung in vitro: involvement of gastrin-releasing peptide-preferring receptors.

J. Gies, E. Haddad, E. Lach, 1993, The American journal of physiology.

Sialic acid is selectively involved in the interaction of agonists with M2 muscarinic acetylcholine receptors.

J. Gies, Y. Landry, 1988, Biochemical and biophysical research communications.

Structural requirements for neuropeptide Y in mast cell and G protein activation.

J. Gies, M. Mousli, J. Pelton, 1995, European journal of pharmacology.

Effects of WIN 64338, a nonpeptide bradykinin B2 receptor antagonist, on guinea‐pig trachea

J. Gies, L. Daeffler, A. Trifilieff, 1995, British journal of pharmacology.

Comparative action of new highly potent bradykinin receptor antagonists in the guinea-pig trachea.

J. Gies, Y. Amrani, A. Trifilieff, 1993, European journal of pharmacology.

Reduced expression of nicotinic AChRs in myotubes from spinal muscular atrophy I patients

A. Arnold, M. Guèye, P. Poindron, 2004, Laboratory Investigation.

High-affinity receptors for bombesin-like peptides in normal guinea pig lung membranes.

J. Gies, A. Trifilieff, Y. Landry, 1991, Life sciences.

Evidence for in vitro expression of B1 receptor in the mouse trachea and urinary bladder

N. Frossard, G. Folkerts, J. Gies, 1999, British journal of pharmacology.

Bradykinin-induced contraction of human peripheral airways mediated by both bradykinin B2 and thromboxane prostanoid receptors.

J. Gies, A. Trifilieff, 1995, American journal of respiratory and critical care medicine.

Muscarinic receptor subtypes in guinea pig airways.

J. Gies, Y. Landry, E. Haddad, 1991, The American journal of physiology.

Bradykinin-induced contraction of guinea pig lung in vitro

J. Gies, M. Mousli, A. Trifilieff, 1994, Naunyn-Schmiedeberg's Archives of Pharmacology.

Interleukin-1 b Induces Bradykinin B 2 Receptor Gene Expression through a Prostanoid Cyclic AMP-Dependent Pathway in Human Bronchial Smooth Muscle Cells

C. Bertrand, J. Gies, F. Schmidlin, 1998 .

Glucocorticoids increase bradykinin B2 receptor gene transcription in cultured guinea-pig tracheal smooth muscle cells

J. Gies, F. Schmidlin, O. Kassel, 1999, Naunyn-Schmiedeberg's Archives of Pharmacology.

Glucocorticoid modulation of muscarinic and β‐adrenergic receptors in guinea pig lung

J. Gies, Y. Landry, D. Scherrer, 1997, Fundamental & clinical pharmacology.

Bradykinin binding sites in healthy and carcinomatous human lung

J. Gies, A. Trifilieff, P. Dumont, 1994, British journal of pharmacology.

Neuraminidase reduces the number of super-high-affinity [3H]oxotremorine-M binding sites in lung.

J. Gies, E. Haddad, 1992, European journal of pharmacology.

Effect of Hoe 140, a new B2 noncompetitive antagonist, on guinea pig tracheal bradykinin receptors.

J. Gies, A. Trifilieff, Y. Landry, 1992, The Journal of pharmacology and experimental therapeutics.

Effect of WIN 64338, a B2 bradykinin receptor antagonist on guinea‐pig tracheal smooth muscle cells in culture

J. Gies, F. Schmidlin, Y. Landry, 1998, Fundamental & clinical pharmacology.

Co-solubilization of bradykinin B2 receptors and angiotensin-converting enzyme from guinea pig lung membranes.

J. Gies, M. Mousli, A. Trifilieff, 1994, Biochimica et biophysica acta.

Evidence for two high-affinity bradykinin binding sites in the guinea-pig lung.

J. Gies, A. Trifilieff, Y. Landry, 1991, European journal of pharmacology.

Glucocorticoids inhibit the bradykinin B2 receptor increase induced by interleukin-1beta in human bronchial smooth muscle cells.

J. Gies, F. Schmidlin, Y. Landry, 1998, European journal of pharmacology.

CD 47 Activation-induced UHRF 1 Over-expression Is Associated with Silencing of Tumor Suppressor Gene p 16 INK 4 A in Glioblastoma Cells

Y. Mély, C. Bronner, M. Alhosin, 2014 .

Association of guinea pig lung bombesin receptors with pertussis toxin-sensitive guanine nucleotide binding proteins.

J. Gies, A. Trifilieff, D. Scherrer, 1994, European journal of pharmacology.

Mapk Activation Via 5-Hydroxytryptamine 1A Receptor is Involved in the Neuroprotective Effects of Xaliproden

J. Warter, P. Poindron, J. Gies, 2005, International journal of immunopathology and pharmacology.

Muscarinic acetylcholine receptor: thermodynamic analysis of the interaction of agonists and antagonists.

J. Gies, B. Ilien, Y. Landry, 1986, Biochimica et biophysica acta.

CD47 activation-induced UHRF1 over-expression is associated with silencing of tumor suppressor gene p16INK4A in glioblastoma cells.

Y. Mély, C. Bronner, M. Alhosin, 2015, Anticancer research.

Membrane phospholipid polar heads influence the coupling of M2 muscarinic receptors to G proteins

C. Bertrand, J. Gies, Y. Landry, 1988, Neurochemical Research.

Inhibition of GTPase activity of Gi proteins and decreased agonist affinity at M2 muscarinic acetylcholine receptors by spermine and methoctramine

J. Gies, A. Chahdi, L. Daeffler, 1999, British journal of pharmacology.

M2-muscarinic receptors: how does ligand binding affinity relate to intrinsic activity?

J. Gies, M. Mousli, L. Daeffler, 1996, Journal of receptor and signal transduction research.

Inhibiting FAK–Paxillin Interaction Reduces Migration and Invadopodia-Mediated Matrix Degradation in Metastatic Melanoma Cells

J. D. De Mey, G. Zuber, P. Rondé, 2021, Cancers.

Quantification of Neurotrophin mRNA Expression in PMN Mouse: Modulation by Xaliproden

P. Passilly-Degrace, J. Warter, P. Poindron, 2004, International journal of immunopathology and pharmacology.

Activation of CD47 receptors causes histamine secretion from mast cells

K. Takeda, J. Gies, Y. Landry, 2009, Cellular and Molecular Life Sciences.

Limoniastrum guyonianum aqueous gall extract induces apoptosis in human cervical cancer cells involving p16INK4A re-expression related to UHRF1 and DNMT1 down-regulation

Y. Mély, C. Bronner, M. Alhosin, 2013, Journal of experimental & clinical cancer research : CR.

Preservation of the secretory response of peritoneal mast cells in the absence of extracellular calcium.

C. Bronner, J. Gies, Y. Landry, 1987, Life sciences.

IL1-β modulates Bradykinin B2 receptors expression through prostaglandins pathway in human bronchial smooth muscle cells in culture (HBSMC)

J. Gies, F. Schmidlin, Y. Landry, 1998 .

Characterization of muscarinic receptors in human, guinea pig and rat lung.

G. Pauli, C. Bertrand, J. Gies, 1989, The Journal of pharmacology and experimental therapeutics.

The Role of Calcium and Magnesium Ions in Uptake of β-Amyloid Peptides by Microglial Cells

P. Poindron, J. Gies, V. Laporte, 2006, International journal of immunopathology and pharmacology.

Synthesis and structure-activity relationships of a series of aminopyridazine derivatives of gamma-aminobutyric acid acting as selective GABA-A antagonists.

C. Wermuth, J. Molimard, M. Héaulme, 1987, Journal of medicinal chemistry.

Human M1-, M2- and M3-muscarinic cholinergic receptors: Binding characteristics of agonists and antagonists

Patrick Vanderheyden, J. Gies, G. Vauquelin, 1990, Journal of the Neurological Sciences.

Expression/activation of α5β1 integrin is linked to the β-catenin signaling pathway to drive migration in glioma cells

N. Etienne-Selloum, L. Choulier, J. Gies, 2016, Oncotarget.

Thymoquinone reduces migration and invasion of human glioblastoma cells associated with FAK, MMP-2 and MMP-9 down-regulation

P. Rondé, J. Gies, C. Lugnier, 2012, Investigational New Drugs.

The M2 muscarinic receptor antagonist methoctramine activates mast cells via pertussis toxin-sensitive G proteins

J. Gies, A. Chahdi, L. Daeffler, 1998, Naunyn-Schmiedeberg's Archives of Pharmacology.

Molecular Drug Targets

J. Gies, Y. Landry, 2008 .

A Metabolomic Approach (1H HRMAS NMR Spectroscopy) Supported by Histology to Study Early Post-transplantation Responses in Islet-transplanted Livers

I. Namer, K. Elbayed, J. Gies, 2016, International journal of biological sciences.

FAK competes for Src to promote migration against invasion in melanoma cells

J. D. De Mey, J. Gies, F. Noulet, 2014, Cell Death and Disease.

Protein dynamics at invadopodia control invasion–migration transitions in melanoma cells

J. Gies, D. Dujardin, D. Bouvard, 2023, Cell Death & Disease.

Stimulation of aryl sulfatase in rat peritoneal macrophages exposed to bone in vitro

J. Gies, C. Dorey, 2006, Calcified Tissue International.

4 – DRUG TARGETS: MOLECULAR MECHANISMS OF DRUG ACTION

J. Gies, Y. Landry, 2003 .

TiO2 Photocatalysis Damages Lipids and Proteins in Escherichia coli

N. Keller, P. Horvatovich, J. Gies, 2014, Applied and Environmental Microbiology.

Complement receptor 3 (CD11b/CD18) is implicated in the elimination of β‐amyloid peptides

P. Poindron, J. Gies, V. Laporte, 2011, Fundamental & clinical pharmacology.

Cyclin dependent kinase inhibitors prevent apoptosis of postmitotic mouse motoneurons.

P. Poindron, J. Gies, A. Appert-Collin, 2006, Life sciences.

Correction: Constitutive Overexpression of Muscarinic Receptors Leads to Vagal Hyperreactivity

N. Dali-Youcef, J. Gies, J. Feldman, 2011, PLoS ONE.

Constitutive Overexpression of Muscarinic Receptors Leads to Vagal Hyperreactivity

N. Dali-Youcef, J. Gies, J. Feldman, 2010, PloS one.

Pro-Inflammatory and Pro-Oxidant Status of Pancreatic Islet In Vitro Is Controlled by TLR-4 and HO-1 Pathways

S. Dal, J. Gies, N. Jeandidier, 2014, PloS one.

Characterization of Long-Term Cultured Cell Lines of Murine Microglia Called MAMI

P. Poindron, J. Gies, V. Laporte, 2005 .

On the use of capillary cytometry for assessing the bactericidal effect of TiO_2. Identification and involvement of reactive oxygen species

Nicolas Keller, N. Keller, J. Gies, 2013, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

Xaliproden (SR57746A) Induces 5-Ht1A Receptors-Mediated Map Kinase Activation in Pc12 Cells

J. Warter, P. Poindron, J. Gies, 2005, International journal of immunopathology and pharmacology.

Synthesis and Structure‐Activity Relationships of a Series of Aminopyridazine Derivatives of γ‐Aminobutyric Acid Acting as Selective GABA‐A Antagonists.

C. Wermuth, M. Héaulme, K. Bizière, 1987 .

Impairment of contractility associated with muscarinic supersensitivity in trachea isolated from diabetic rats: lack of correlation with ultrastructural changes or quinuclidinyl benzylate binding to lung membranes

J. Gies, J. Serrano, G. Cros, 1992, Molecular and Cellular Biochemistry.

Site-directed mutagenesis of the putative human muscarinic M2 receptor binding site.

C. Guenet, S. Trumpp-Kallmeyer, J. Gies, 1999, European journal of pharmacology.

Receptor-independent activation of mast cells by bradykinin and related peptides

J. Gies, M. Mousli, Y. Landry, 1993, Trends in Neurosciences.

Gastrin releasing peptide-preferring bombesin binding sites in human lung.

D. Coy, J. Gies, Y. Landry, 1994, European journal of pharmacology.

Heterogeneity of guinea-pig lung muscarinic receptors revealed by [3H]4-DAMP-binding.

J. Gies, A. Trifilieff, Y. Landry, 1993, Pulmonary pharmacology.

Cardiac Muscarinic Receptor Overexpression in Sudden Infant Death Syndrome

Caroline Rambaud, N. Dali-Youcef, J. Gies, 2010, PloS one.

Instant blood-mediated inflammatory reaction during islet transplantation: the role of Toll-like receptors signaling pathways.

J. Gies, N. Jeandidier, S. Sigrist, 2011, Transplantation proceedings.

Activation of CD47 receptors causes histamine secretion from mast cells

J. Gies, Y. Landry, N. Niederhoffer, 2009, Cellular and Molecular Life Sciences.