S. Sellers

发表

Introduction of a xenogeneic gene via hematopoietic stem cells leads to specific tolerance in a rhesus monkey model.

J. Tisdale, Y. Hanazono, C. Dunbar, 2000, Molecular therapy : the journal of the American Society of Gene Therapy.

Engraftment of MDR1 and NeoR gene-transduced hematopoietic cells after breast cancer chemotherapy.

I. Pastan, M. Gottesman, D. Venzon, 1999, Blood.

Ex vivo expansion of genetically marked rhesus peripheral blood progenitor cells results in diminished long-term repopulating ability.

J. Tisdale, Y. Hanazono, C. Dunbar, 1998, Blood.

Long-term clinical and molecular follow-up of large animals receiving retrovirally transduced stem and progenitor cells: no progression to clonal hematopoiesis or leukemia.

C. von Kalle, A. Nienhuis, C. A. Blau, 2004, Molecular therapy : the journal of the American Society of Gene Therapy.

Peripheral blood CD34+ cells differ from bone marrow CD34+ cells in Thy-1 expression and cell cycle status in nonhuman primates mobilized or not mobilized with granulocyte colony-stimulating factor and/or stem cell factor.

R. Donahue, S. Sellers, B. Agricola, 1996, Blood.

Long-term in vivo expression of the human glucocerebrosidase gene in nonhuman primates after CD34+ hematopoietic cell transduction with cell-free retroviral vector preparations.

S. Karlsson, R. Brady, C. Dunbar, 1995, Proceedings of the National Academy of Sciences of the United States of America.

The effect of multidrug-resistance 1 gene versus neo transduction on ex vivo and in vivo expansion of rhesus macaque hematopoietic repopulating cells.

J. Tisdale, C. Dunbar, R. Donahue, 2001, Blood.

Ex vivo expansion of retrovirally transduced primate CD34+ cells results in overrepresentation of clones with MDS1/EVI1 insertion sites in the myeloid lineage after transplantation.

R. Childs, C. Dunbar, R. Donahue, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

Recurrent retroviral vector integration at the Mds1/Evi1 locus in nonhuman primate hematopoietic cells.

C. von Kalle, M. Laukkanen, C. Dunbar, 2005, Blood.

Recombinant adeno-associated virus (rAAV)-mediated expression of a human gamma-globin gene in human progenitor-derived erythroid cells.

R. Samulski, N. Young, A. Nienhuis, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Infection of mononucleated phagocytes with human cytomegalovirus.

N. Young, J. Maciejewski, S. Sellers, 1993, Virology.

Comparative engraftment and clonality of macaque HSPCs expanded on human umbilical vein endothelial cells versus non-expanded cells

P. Dagur, Chuanfeng Wu, Michael Ginsberg, 2021, Molecular therapy. Methods & clinical development.

Analysis of origin and optimization of expansion and transduction of circulating peripheral blood endothelial progenitor cells in the rhesus macaque model.

C. Dunbar, R. Donahue, S. Sellers, 2002, Human gene therapy.

Regulated Apoptosis of Genetically Modified Hematopoietic Stem and Progenitor Cells Via an Inducible Caspase‐9 Suicide Gene in Rhesus Macaques

K. Keyvanfar, C. Dunbar, R. Donahue, 2015, Stem cells.

The effects of SCF/G-CSF prestimulation on radiation sensitivity and engraftment in nonmyeloablated murine hosts.

N. Giri, J. Tisdale, T. Wu, 2001, Experimental hematology.

After Breast Cancer Chemotherapy Engraftment of MDR1 and NeoR Gene-Transduced Hematopoietic Cells

I. Pastan, M. Gottesman, D. Venzon, 2013 .

No discrepancy between in vivo gene marking efficiency assessed in peripheral blood populations compared with bone marrow progenitors or CD34+ cells.

S. Karlsson, D. Williams, D. Bodine, 1999, Human gene therapy.

Transduction of hematopoietic stem cells in humans and in nonhuman primates

D. Bodine, T. Soma, J. Zujewski, 1997, Stem cells.

In vivo persistence of retrovirally transduced murine long-term repopulating cells is not limited by expression of foreign gene products in the fully or minimally myeloablated setting.

N. Giri, J. Tisdale, Y. Hanazono, 2001, Human gene therapy.

Prolonged high-level detection of retrovirally marked hematopoietic cells in nonhuman primates after transduction of CD34+ progenitors using clinically feasible methods.

J. Tisdale, C. Dunbar, R. Donahue, 2000, Molecular therapy : the journal of the American Society of Gene Therapy.

Distinct Genomic Integration of MLV and SIV Vectors in Primate Hematopoietic Stem and Progenitor Cells

Christof von Kalle, Manfred Schmidt, Peiman Hematti, 2004, PLoS biology.

Efficient Characterization of Retro‐, Lenti‐, and Foamyvector‐Transduced Cell Populations by High‐Accuracy Insertion Site Sequencing

S. Karlsson, H. Glimm, M. Wissler, 2003, Annals of the New York Academy of Sciences.

primates The impact of low-dose busulfan on clonal dynamics in nonhuman

M. Laukkanen, R. Donahue, S. Sellers, 2013 .

The impact of low-dose busulfan on clonal dynamics in nonhuman primates.

C. von Kalle, M. Laukkanen, C. Dunbar, 2004, Blood.

No impact of lentiviral transduction on hematopoietic stem/progenitor cell telomere length or gene expression in the rhesus macaque model.

B. Dumitriu, N. Young, R. Calado, 2014, Molecular therapy : the journal of the American Society of Gene Therapy.

Integration-specific In Vitro Evaluation of Lentivirally Transduced Rhesus CD34+ Cells Correlates With In Vivo Vector Copy Number

J. Tisdale, C. Dunbar, R. Donahue, 2013, Molecular therapy. Nucleic acids.

Integration-specific In Vitro Evaluation of Lentivirally Transduced Rhesus CD34+ Cells Correlates With In Vivo Vector Copy Number.

J. Tisdale, C. Dunbar, R. Donahue, 2013, Molecular therapy. Nucleic acids.

No Evidence of Clonal Dominance in Primates up to 4 Years Following Transplantation of Multidrug Resistance 1 Retrovirally Transduced Long‐Term Repopulating Cells

W. Zeller, I. Roeder, C. Dunbar, 2007, Stem cells.

Recurrent Retroviral Vector Integration at the MDS1-EVI1 Locus in Rhesus Long-Term Repopulating Hematopoietic Stem Cells.

M. Laukkanen, C. Dunbar, R. Donahue, 2004 .

Acquired somatic mutations in PNH reveal long-term maintenance of adaptive NK cells independent of HSPCs.

N. Young, Chuanfeng Wu, C. Dunbar, 2017, Blood.

Improved retroviral gene transfer into murine and Rhesus peripheral blood or bone marrow repopulating cells primed in vivo with stem cell factor and granulocyte colony-stimulating factor.

D. Bodine, C. Dunbar, R. Donahue, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Clonal tracking of erythropoiesis in rhesus macaques

Chuanfeng Wu, C. Dunbar, R. Donahue, 2019, Haematologica.

Expression of interferon-gamma by stromal cells inhibits murine long-term repopulating hematopoietic stem cell activity.

N. Young, Y. Hanazono, S. Sellers, 1999, Experimental hematology.

Transplantation and gene transfer of the human glucocerebrosidase gene into immunoselected primate CD34+Thy-1+ cells.

P. Lansdorp, R. Donahue, S. Sellers, 1996, Blood.

Retroviral transduction efficiency of G-CSF+SCF-mobilized peripheral blood CD34+ cells is superior to G-CSF or G-CSF+Flt3-L-mobilized cells in nonhuman primates.

C. Dunbar, R. Donahue, S. Sellers, 2003, Blood.

Avoidance of stimulation improves engraftment of cultured and retrovirally transduced hematopoietic cells in primates.

C. Dunbar, R. Donahue, I. Kato, 2001, The Journal of clinical investigation.

Retroviral transduction and engraftment ability of primate hematopoietic progenitor and stem cells transduced under serum-free versus serum-containing conditions.

C. Dunbar, R. Donahue, S. Sellers, 2002, Molecular therapy : the journal of the American Society of Gene Therapy.

Many multipotential gene-marked progenitor or stem cell clones contribute to hematopoiesis in nonhuman primates.

J. Tisdale, C. Dunbar, R. Donahue, 2000, Blood.

Eltrombopag for patients with moderate aplastic anemia or uni-lineage cytopenias.

B. Dumitriu, N. Young, M. Albitar, 2020, Blood advances.

Effect of chronic cytokine therapy on clonal dynamics in nonhuman primates.

C. von Kalle, D. Follmann, C. Dunbar, 2004, Blood.

The presence of the carboxy-terminal fragment of fibronectin allows maintenance of non-human primate long-term hematopoietic repopulating cells during extended ex vivo culture and transduction.

J. Tisdale, C. Dunbar, R. Donahue, 2004, Experimental hematology.