J. Ling

发表

Stable and unstable transgene integration sites in the human genome: extinction of the Green Fluorescent Protein transgene in K562 cells.

D. Tuan, A. Migliaccio, M. Keskintepe, 2000, Gene.

HS2 Enhancer Function Is Blocked by a Transcriptional Terminator Inserted between the Enhancer and the Promoter*[boxs]

D. Tuan, J. Ling, W. Pi, 2004, Journal of Biological Chemistry.

A facilitated tracking and transcription mechanism of long-range enhancer function

D. Tuan, J. Ling, W. Pi, 2007, Nucleic acids research.

Immune Cell Production of Interleukin 17 Induces Stem Cell Features of Pancreatic Intraepithelial Neoplasia Cells.

A. Maitra, S. Leach, Kyle Chang, 2018, Gastroenterology.

Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death.

K. Flaherty, W. El-Deiry, D. Dicker, 2007, Cancer cell.

Expression of Concern: Cooperativity of Oncogenic K-Ras and Downregulated p16/INK4A in Human Pancreatic Tumorigenesis

J. Cheng, Dihua Yu, Huamin Wang, 2019, PloS one.

The ERV-9 LTR enhancer is not blocked by the HS5 insulator and synthesizes through the HS5 site non-coding, long RNAs that regulate LTR enhancer function.

D. Tuan, C. Bengra, J. Ling, 2003, Nucleic acids research.

Identification of cisplatin sensitizers through high-throughput combinatorial screening.

P. Chiao, Peng Huang, J. Ling, 2018, International journal of oncology.

Two Birds with One Stone: Therapeutic Targeting of IL1α Signaling Pathways in Pancreatic Ductal Adenocarcinoma and the Cancer-Associated Fibroblasts.

P. Chiao, J. Ling, 2019, Cancer discovery.

Nardilysin-Regulated Scission Mechanism Activates Polo-like Kinase 3 to Suppress the Development of Pancreatic Cancer

Yu Cao, J. Tainer, A. Maitra, 2022, bioRxiv.

SOX9 activity is induced by oncogenic Kras to affect MDC1 and MCMs expression in pancreatic cancer

P. Chiao, L. Song, J. Ling, 2018, Oncogene.

Kras, Pten, NF-κB, and inflammation: dangerous liaisons.

P. Chiao, J. Ling, 2011, Cancer discovery.

Supplemental Data Reduction of TRAIL-Induced Mcl-1 and cIAP 2 by c-Myc or Sorafenib Sensitizes Resistant Human Cancer Cells to TRAIL-Induced Death

K. Flaherty, D. Dicker, Wenge Wang, 2007 .

ATF4/TXNIP/REDD1/mTOR signaling mediates the antitumor activities of liver X receptor in pancreatic cancers

P. Chiao, J. Ling, Aijun Zhang, 2022, Cancer innovation.

3D imaging analysis on an organoid-based platform guides personalized treatment in pancreatic ductal adenocarcinoma

Jeffrey E. Lee, R. DePinho, A. Maitra, 2022, The Journal of clinical investigation.

Wound-induced HB-EGF ectodomain shedding and EGFR activation in corneal epithelial cells.

J. Ling, Z. Dong, Keping Xu, 2004, Investigative ophthalmology & visual science.

Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma

Jun Yao, R. DePinho, M. Hung, 2017, Nature Communications.

The HS2 enhancer of the beta-globin locus control region initiates synthesis of non-coding, polyadenylated RNAs independent of a cis-linked globin promoter.

D. Tuan, B. Emerson, J. Ling, 2005, Journal of molecular biology.

The Long Terminal Repeat (LTR) of ERV-9 Human Endogenous Retrovirus Binds to NF-Y in the Assembly of an Active LTR Enhancer Complex NF-Y/MZF1/GATA-2*

D. Tuan, J. Ling, W. Pi, 2005, Journal of Biological Chemistry.

Dynamic retrotransposition of ERV-9 LTR and L1 in the beta-globin gene locus during primate evolution.

D. Tuan, M. Goodman, N. Anagnou, 2004, Molecular phylogenetics and evolution.

Defective feedback regulation of NF-κB underlies Sjögren’s syndrome in mice with mutated κB enhancers of the IκBα promoter

Huamin Wang, J. Fleming, P. Chiao, 2010, Proceedings of the National Academy of Sciences.

Long-range function of an intergenic retrotransposon

Ali Eroglu, Xingguo Zhu, D. Tuan, 2010, Proceedings of the National Academy of Sciences.

The Solitary Long Terminal Repeats of ERV-9 Endogenous Retrovirus Are Conserved during Primate Evolution and Possess Enhancer Activities in Embryonic and Hematopoietic Cells

D. Tuan, M. Keskintepe, R. Bollag, 2002, Journal of Virology.

KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma.

Ruiying Zhao, Dung-Fang Lee, Jinsong Liu, 2012, Cancer cell.

Cooperativity of Oncogenic K-Ras and Downregulated p16/INK4A in Human Pancreatic Tumorigenesis

Dihua Yu, Huamin Wang, J. Fleming, 2014, PloS one.

The LTR enhancer of ERV-9 human endogenous retrovirus is active in oocytes and progenitor cells in transgenic zebrafish and humans.

D. Tuan, Shuo Lin, J. Ling, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Modulation of pancreatic cancer chemoresistance by inhibition of TAK1.

D. Melisi, J. Abbruzzese, P. Chiao, 2011, Journal of the National Cancer Institute.

Suppression of stromal-derived Dickkopf-3 (DKK3) inhibits tumor progression and prolongs survival in pancreatic ductal adenocarcinoma

Jeffrey E. Lee, C. Niehrs, A. Maitra, 2018, Science Translational Medicine.

SMAD4 Regulates Cell Motility through Transcription of N-Cadherin in Human Pancreatic Ductal Epithelium

Huamin Wang, D. Chatterjee, M. Katz, 2014, PloS one.

Transforming Growth Factor-β Limits Secretion of Lumican by Activated Stellate Cells within Primary Pancreatic Adenocarcinoma Tumors

Huamin Wang, D. Chatterjee, M. Katz, 2016, Clinical Cancer Research.

Regulation of PD-L1 expression in K-ras-driven cancers through ROS-mediated FGFR1 signaling

C. Glorieux, P. Chiao, Peng Huang, 2020, Redox biology.

Oral Poly(ADP-Ribose) Polymerase-1 Inhibitor BSI-401 Has Antitumor Activity and Synergizes with Oxaliplatin against Pancreatic Cancer, Preventing Acute Neurotoxicity

P. Dougherty, D. Melisi, J. Abbruzzese, 2009, Clinical Cancer Research.

IL1 Receptor Antagonist Inhibits Pancreatic Cancer Growth by Abrogating NF-κB Activation

D. Melisi, J. Fleming, P. Chiao, 2015, Clinical Cancer Research.

IL 1 Receptor Antagonist Inhibits Pancreatic Cancer Growth by Abrogating NFk B Activation

D. Melisi, J. Fleming, P. Chiao, 2016 .

IL1 Receptor Antagonist Inhibits Pancreatic Cancer Growth by Abrogating NF-κB Activation

D. Melisi, J. Fleming, P. Chiao, 2015, Clinical Cancer Research.

Cisplatin and gemcitabine exert opposite effects on immunotherapy with PD-1 antibody in K-ras-driven cancer

Huamin Wang, P. Chiao, Hui Zhang, 2021, Journal of advanced research.

Constitutive activation of p38 MAPK in tumor cells contributes to osteolytic bone lesions in multiple myeloma

R. Orlowski, L. Kwak, J. Ling, 2012, Leukemia.

Smad4 Deficiency Promotes Pancreatic Cancer Immunogenicity by Activating the Cancer‐Autonomous DNA‐Sensing Signaling Axis

Peng Huang, Shuai He, J. Bei, 2022, Advanced science.

The overexpression of long intergenic ncRNA00162 induced by RelA/p65 promotes growth of pancreatic ductal adenocarcinoma

Jie Fu, P. Chiao, J. Ling, 2020, Cell proliferation.

Recombinant Thrombomodulin Has Anti-tumor Effects and Enhances the Effects of Gemcitabine for Pancreatic Cancer Through G-protein Coupled Receptor 15

Jie Fu, P. Chiao, J. Ling, 2022, AntiCancer Research.

NEMO peptide inhibits the growth of pancreatic ductal adenocarcinoma by blocking NF-κB activation.

P. Chiao, J. Ling, Min Wu, 2017, Cancer letters.

KrasG12D-induced IKK2/β/NF-κB activation by IL-1α and p62 feedforward loops is required for development of pancreatic ductal adenocarcinoma.

M. Hung, Huamin Wang, I. Lemischka, 2012, Cancer cell.

Oral Poly(ADP-Ribose) Polymerase-1 Inhibitor BSI-401 Has Antitumor Activity and Synergizes with Oxaliplatin against Pancreatic Cancer, Preventing Acute Neurotoxicity

P. Dougherty, D. Melisi, J. Abbruzzese, 2009, Clinical Cancer Research.

Malignant transformation by oncogenic K‐ras requires IDH2‐mediated reductive carboxylation to promote glutamine utilization

P. Chiao, Peng Huang, J. Ling, 2022, Cancer communications.