A. Thrasher

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Pure populations of transduced primary human cells can be produced using GFP expressing herpes virus vectors and flow cytometry

A. Pizzey, R. Coffin, S. Thomas, 1998, Gene Therapy.

ASGCT 20(th) Anniversary Special Issue of Molecular Therapy: Evolving Gene Therapy in Primary Immunodeficiency

David A. Williams, A. Thrasher, 2017 .

Current progress on gene therapy for primary immunodeficiencies

A. Thrasher, L. Zhang, A. Thrasher, 2013, Gene Therapy.

Gene therapy for primary immunodeficiency

A. Thrasher, A. Thrasher, C. Kinnon, 2011, Current opinion in pediatrics.

In vivo gene transfer to the mouse eye using an HIV-based lentiviral vector; efficient long-term transduction of corneal endothelium and retinal pigment epithelium

Kathryn L. Parsley, R. Ali, J. Bainbridge, 2001, Gene Therapy.

Efficient and selective AAV2-mediated gene transfer directed to human vascular endothelial cells.

M. Hallek, R. Ali, A. Thrasher, 2001, Molecular therapy : the journal of the American Society of Gene Therapy.

High efficiency gene transfer to human hematopoietic SCID-repopulating cells under serum-free conditions.

A. Thrasher, M. Grez, A. Thrasher, 1998, Blood.

Long-term expression from non-integrating lentiviral vectors in muscle

Nj Ward, Luis Apolonia, Gerben Bouma, 2007 .

Familial disseminated atypical mycobacterial infection in childhood: a human mycobacterial susceptibility gene?

I. N. Brown, M. Newport, J. Blackwell, 1995, The Lancet.

Genetic variants associated with neutrophil function in aggressive periodontitis and healthy controls.

S. Burns, G. Bouma, A. Thrasher, 2010, Journal of periodontology.

mice by prenatal gene therapy Permanent phenotypic correction of Hemophilia B in immunocompetent

A. Georgiadis, R. Ali, A. Thrasher, 2013 .

Intraocular gene delivery of ciliary neurotrophic factor results in significant loss of retinal function in normal mice and in the Prph2Rd2/Rd2 model of retinal degeneration

R. Ali, J. Bainbridge, A. Thrasher, 2003, Gene Therapy.

A defined window for efficient gene marking of severe combined immunodeficient-repopulating cells using a gibbon ape leukemia virus-pseudotyped retroviral vector.

R. Levinsky, A. Thrasher, M. Grez, 2000, Human gene therapy.

Development of non-integrating lentiviral vectors

Luis Apolonia, Aj Thrasher, Simon N. Waddington, 2006 .

Optimization of recombinant adeno-associated virus production using an herpes simplex virus amplicon system.

S. Fauser, R. Ali, A. Thrasher, 2001, Journal of virological methods.

Adeno-associated virus gene transfer to mouse retina.

D. Hunt, S. Bhattacharya, R. Levinsky, 1998, Human gene therapy.

Gene transfer into the mouse retina mediated by an adeno-associated viral vector.

D. Hunt, R. Levinsky, S. Bhattacharya, 1996, Human molecular genetics.

Stable rAAV-mediated transduction of rod and cone photoreceptors in the canine retina

D. Charteris, A. Georgiadis, R. Ali, 2003, Gene Therapy.

Hypoxia-regulated transgene expression in experimental retinal and choroidal neovascularization

R. Ali, J. Bainbridge, A. Thrasher, 2003, Gene Therapy.

Immunodeficiency: Long-term persistence of a polyclonal t cell repertoire after gene therapy for X-linked severe combined immunodeficiency

Kathryn L. Parsley, S. Cooray, A. Thrasher, 2011 .

An immune response after intraocular administration of an adenoviral vector containing a β galactosidase reporter gene slows retinal degeneration in the rd mouse

R. Ali, A. Thrasher, S. Bhattacharya, 2001, The British journal of ophthalmology.

Enhanced human cell engraftment in mice deficient in RAG2 and the common cytokine receptor gamma chain.

J. D. Di Santo, A. Thrasher, J. Goldman, 1998, British journal of haematology.

Correction of SCID-X1 using an enhancerless Vav promoter.

J. Bueren, F. Zhang, A. Thrasher, 2011, Human gene therapy.

[Gene therapy of SCID-X1].

A. Schambach, A. Thrasher, A. Thrasher, 2007, Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz.

Gentherapie der SCID-X1

A. Schambach, A. Thrasher, U. Modlich, 2007, Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz.

Intrinsic defects of B cell function in X‐linked severe combined immunodeficiency

P. Veys, A. Thrasher, A. Thrasher, 2000, European journal of immunology.

of FVII at levels that protect against fatal spontaneous hemorrhage AAV-mediated gene transfer in the perinatal period results in expression

J. Gray, C. Morton, A. Davidoff, 2014 .

Immune responses limit adenovirally mediated gene expression in the adult mouse eye

D. Hunt, S. Bhattacharya, D. Baker, 1998, Gene Therapy.

Co-injection of adenovirus expressing CTLA4-Ig prolongs adenovirally mediated lacZ reporter gene expression in the mouse retina

A. Thrasher, S. Bhattacharya, D. Baker, 1997, Gene Therapy.

WASP and WIP regulate podosomes in migrating leukocytes

A. Thrasher, A. Thrasher, Y. Calle, 2008, Journal of microscopy.

Molecular Evidence of Genome Editing in a Mouse Model of Immunodeficiency

Rafael J. Yáñez-Muñoz, C. von Kalle, P. Gregory, 2018, Scientific Reports.

Permanent partial phenotypic correction and tolerance in a mouse model of hemophilia B by stem cell gene delivery of human factor IX

N. Wright, R. Ali, A. Thrasher, 2006, Gene Therapy.

Identification and characterization of RBM12 as a novel regulator of fetal hemoglobin expression

R. Hardison, B. Giardine, C. Keller, 2022, Blood advances.

Transfection-free and scalable recombinant AAV vector production using HSV/AAV hybrids

R. Coffin, A. Thrasher, A. Mistry, 2004, Gene Therapy.

T cell transduction and suicide with an enhanced mutant thymidine kinase

A. Thrasher, C. Kinnon, W. Qasim, 2002, Gene Therapy.

Adeno-associated virus gene transfer to mouse retina. Human Gene Therapy

D. Hunt, S. Bhattacharya, R. Levinsky, 1998 .

Immunotherapy for neuroblastoma using syngeneic fibroblasts transfected with IL-2 and IL-12

A. Thrasher, S. Grosse, S. Hart, 2007, British Journal of Cancer.

Cerebral aspergilloma in a child with autosomal recessive chronic granulomatous disease.

G. Mieli-Vergani, A. Thrasher, A. Dean, 1993, Archives of disease in childhood.

Topical cidofovir for severe molluscum contagiosum

A. Thrasher, K. Lacey, J. Harper, 1999, The Lancet.

CHAPTER 17 – Disorders of phagocyte function

Aj Thrasher, G Bouma, G. Bouma, 2011 .

Transgene optimization significantly improves SIN vector titers, gp91phox expression and reconstitution of superoxide production in X-CGD cells

A. Schambach, A. Thrasher, M. Grez, 2009, Gene Therapy.

Lipid-mediated enhancement of transfection by a nonviral integrin-targeting vector.

R. Levinsky, C. Mailhos, R. Ali, 1998, Human gene therapy.

Gene replacement therapy in the retinal degeneration slow (rds) mouse: the effect on retinal degeneration following partial transduction of the retina.

R. Ali, J. Bainbridge, A. Thrasher, 2001, Human molecular genetics.

Wiskott Aldrich syndrome protein regulates non-selective autophagy and mitochondrial homeostasis in human myeloid cells

C. Hess, A. Worth, A. Thrasher, 2020, bioRxiv.

Improvement of neuronal visual responses in the superior colliculus in Prph2 Rd2/Rd2 mice following gene therapy

T. Salt, R. Ali, A. Thrasher, 2004, Molecular and Cellular Neuroscience.

Progress and prospects: gene therapy clinical trials (part 1) (vol 14, pg 1439, 2007)

R. Ali, J. Bainbridge, T. Flotte, 2007 .

Correction of murine Rag1 deficiency by self-inactivating lentiviral vector-mediated gene transfer

A. Schambach, M. Cavazzana‐Calvo, F. Staal, 2011, Leukemia.

The Wiskott–Aldrich syndrome

A. Thrasher, A. Thrasher, C. Kinnon, 2000, Clinical and experimental immunology.

Single Nucleus Sequencing of Human Colon Visceral Smooth Muscle Cells, PDGFRα Cells, and Interstitial Cells of Cajal

R. Heuckeroth, A. Thrasher, Sabine Schneider, 2022, bioRxiv.

Normal development of human fetal hematopoiesis between eight and seventeen weeks' gestation.

C. Rodeck, E. Jauniaux, A. Thrasher, 2000, American journal of obstetrics and gynecology.

Erratum: Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy (New England Journal of Medicine (April 18, 2002) 346 (1185-1193))

Aj Thrasher, Lily E. Leiva, F Le Deist, 2002 .

Long-term preservation of retinal function in the RCS rat model of retinitis pigmentosa following lentivirus-mediated gene therapy

Peter M. G. Munro, R. Ali, J. Bainbridge, 2005, Gene Therapy.

Detailed characterization of the human aorta-gonad-mesonephros region reveals morphological polarity resembling a hematopoietic stromal layer.

A. Thrasher, C. Kinnon, P. Thorogood, 1999, Developmental dynamics : an official publication of the American Association of Anatomists.

New Powerful Software for Copy Number Analysis of Exome Sequence Data, Exomedepth, Discovers Novel Mutations in Primary Immunodeficiency Patients

Michael Epstein, Aj Thrasher, Nicholas W. Wood, 2012 .

Inhibition of retinal neovascularisation by gene transfer of soluble VEGF receptor sFlt-1

R. Ali, A. Thrasher, A. Thrasher, 2002, Gene Therapy.

Kinetics of transgene expression in mouse retina following sub-retinal injection of recombinant adeno-associated virus

P. Luthert, R. Ali, A. Thrasher, 2002, Vision Research.

High-titer recombinant adeno-associated virus production from replicating amplicons and herpes vectors deleted for glycoprotein H.

R. Levinsky, S. Inglis, R. Ali, 1999, Human gene therapy.

Long-term safety and efficacy of lentiviral hematopoietic stem/progenitor cell gene therapy for Wiskott–Aldrich syndrome

E. Macintyre, A. Kauskot, A. Toubert, 2022, Nature Medicine.

Single Nucleus Sequencing of Human Colon Myenteric Plexus–Associated Visceral Smooth Muscle Cells, Platelet Derived Growth Factor Receptor Alpha Cells, and Interstitial Cells of Cajal

R. Heuckeroth, A. Thrasher, Sabine Schneider, 2022, Gastro hep advances.

Oncogenesis following delivery of a non-primate lentiviral gene therapy vector to fetal mice

Simon N. Waddington, Michael Themis, Manfred Schmidt, 2005 .

ZFN-driven gene targeting to correct mouse Prkdc scid deficiency

Steven J. Howe, Juan A. Bueren, Aj Thrasher, 2011 .

Update on gene therapy for chronic granulomatous disease

A. Jauch, B. Burwinkel, A. Thrasher, 2007 .

Modeling and Increasing the Genome Accessibility of Viral Integration Sites

Alessandro Aiuti, Steven J. Howe, Robin R. Ali, 2009 .

Update on treatment of human SCID-X1 by somatic gene therapy using a pseudotyped gammaretroviral vector

Kathryn L. Parsley, A. Thrasher, S. Howe, 2004 .

Ultrastructural visualization of complex carbohydrates in eosinophilic leukocytes.

S. Spicer, M. Takagi, A. Thrasher, 1982, The American journal of anatomy.

Targeted Lentiviral Gene Therapy to Rescue the X-CGD Phenotype

Christine Kinnon, Juan A. Bueren, Aj Thrasher, 2010 .

Erratum: Hematopoietic stem cell gene therapy for adenosine deaminase-deficient severe combined immunodeficiency leads to long-term immunological recovery and metabolic correction (Science Translational Medicine (2013) 5 (168er1))

P. Veys, S. Cooray, A. Thrasher, 2013 .