J. Sleeman

发表

Dynamic interactions between splicing snRNPs, coiled bodies and nucleoli revealed using snRNP protein fusions to the green fluorescent protein.

A. Lamond, J. Sleeman, C. Lyon, 1998, Experimental cell research.

The SMN Protein is a Key Regulator of Nuclear Architecture in Differentiating Neuroblastoma Cells

N. P. Kinnear, J. Sleeman, A. Clelland, 2009, Traffic.

Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex

Juri Rappsilber, Matthias Mann, Cinzia Calvio, 1998, Nature Genetics.

Time-lapse imaging reveals dynamic relocalization of PP1gamma throughout the mammalian cell cycle.

Jason R Swedlow, Yun Wah Lam, Laura Trinkle-Mulcahy, 2003, Molecular biology of the cell.

Dynamic targeting of protein phosphatase 1 within the nuclei of living mammalian cells.

A. Lamond, L. Trinkle-Mulcahy, J. Sleeman, 2001, Journal of cell science.

The Cajal body and the nucleolus: “In a relationship” or “It's complicated”?

L. Trinkle-Mulcahy, J. Sleeman, 2017, RNA biology.

snRNP protein expression enhances the formation of Cajal bodies containing p80-coilin and SMN.

A. Lamond, J. Sleeman, P. Ajuh, 2001, Journal of cell science.

Molecular and functional characterization of microsomal UDP-glucuronic acid uptake by members of the nucleotide sugar transporter (NST) family.

B. Burchell, M. Coughtrie, J. Sleeman, 2006, The Biochemical journal.

Changes in intranuclear mobility of mature snRNPs provide a mechanism for splicing defects in spinal muscular atrophy

J. Sleeman, A. Clelland, Alexandra Bales, 2012, Journal of Cell Science.

Changes in intra-nuclear mobility of mature snRNPs provide a mechanism for splicing defects in Spinal Muscular Atrophy

J. Sleeman, A. Clelland, Alexandra Bales, 2012 .

Cajal body proteins SMN and Coilin show differential dynamic behaviour in vivo

A. Lamond, A. Prescott, S. Ogg, 2003, Journal of Cell Science.

Nuclear organization of pre-mRNA splicing factors.

A. Lamond, J. Sleeman, 1999, Current Opinion in Cell Biology.

Inhibition of protein dephosphorylation results in the accumulation of splicing snRNPs and coiled bodies within the nucleolus.

A. Lamond, J. Sleeman, C. Lyon, 1997, Experimental cell research.

Small nuclear RNAs and mRNAs: linking RNA processing and transport to spinal muscular atrophy.

J. Sleeman, 2013, Biochemical Society transactions.

Condensation properties of stress granules and processing bodies are compromised in myotonic dystrophy type 1

A. Prescott, J. Sleeman, Panagiotis P Papavasiliou, 2022, Disease models & mechanisms.

Neurochondrin interacts with the SMN protein suggesting a novel mechanism for spinal muscular atrophy pathology

Ewout J. N. Groen, S. Shirran, C. Botting, 2017, Journal of Cell Science.

Nuclear bodies: new insights into assembly/dynamics and disease relevance.

L. Trinkle-Mulcahy, J. Sleeman, 2014, Current opinion in cell biology.

Newly assembled snRNPs associate with coiled bodies before speckles, suggesting a nuclear snRNP maturation pathway

A. Lamond, J. Sleeman, 1999, Current Biology.

Time-resolved quantitative proteomics implicates the core snRNP protein SmB together with SMN in neural trafficking

J. James, A. Prescott, L. Trinkle-Mulcahy, 2014, Journal of Cell Science.

Time-resolved quantitative proteomics implicates the core snRNP protein , SmB , together with the Survival of Motor Neuron protein , in neural trafficking

J. James, A. Prescott, L. Trinkle-Mulcahy, 2014 .

FRET analyses of the U2AF complex localize the U2AF35/U2AF65 interaction in vivo and reveal a novel self-interaction of U2AF35.

J. Ellenberg, A. Lamond, L. Trinkle-Mulcahy, 2005, RNA.

Nuclear substructure and dynamics

A. Lamond, J. Sleeman, 2003, Current Biology.

SMN co-localises with the mRNA binding proteins HuD , IMP 1 and hnRNP R and is involved in

S. Shirran, C. Botting, J. Sleeman, 2017 .

Protein phosphatase 4 interacts with the Survival of Motor Neurons complex and enhances the temporal localisation of snRNPs

A. Lamond, M. Peggie, N. Morrice, 2003, Journal of Cell Science.

Transcriptionally correlated subcellular dynamics of MBNL1 during lens development and their implication for the molecular pathology of myotonic dystrophy type 1.

A. Prescott, J. Sleeman, Stewart M Coleman, 2014, The Biochemical journal.

A Direct Interaction between the Carboxyl-terminal Region of CDC5L and the WD40 Domain of PLRG1 Is Essential for Pre-mRNA Splicing*

A. Lamond, J. Sleeman, J. Chusainow, 2001, The Journal of Biological Chemistry.

A regulatory role for CRM1 in the multi-directional trafficking of splicing snRNPs in the mammalian nucleus

J. Sleeman, 2007, Journal of Cell Science.

Phase-separated stress granules and processing bodies are compromised in Myotonic Dystrophy Type 1

A. Prescott, J. Sleeman, Panagiotis P Papavasiliou, 2021, bioRxiv.

Dynamics of the mammalian nucleus: can microscopic movements help us to understand our genes?

J. Sleeman, 2004, Philosophical Transactions of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences.