E. E. Zhang

发表

Clocks not winding down: unravelling circadian networks

Steve A. Kay, S. Kay, E. E. Zhang, 2010, Nature Reviews Molecular Cell Biology.

Intercellular Coupling Confers Robustness against Mutations in the SCN Circadian Clock Network

Francis J. Doyle, Steve A. Kay, Joseph S. Takahashi, 2007, Cell.

A Genome-wide RNAi Screen for Modifiers of the Circadian Clock in Human Cells

Andrew I. Su, Jon W. Huss, John B. Hogenesch, 2009, Cell.

A microfluidic approach for experimentally modelling the intercellular coupling system of a mammalian circadian clock at single-cell level.

E. E. Zhang, Yanyi Huang, Y. Pang, 2020, Lab on a chip.

Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1

Yanli Wang, T. Cai, Liping Zhao, 2019, Science Translational Medicine.

Identification of entacapone as a chemical inhibitor of FTO mediating metabolic regulation through FOXO1.

N. Huang, P. Li, T. Cai, 2019 .

Downregulation of HIF-1a sensitizes U251 glioma cells to the temozolomide (TMZ) treatment.

E. E. Zhang, S. Lv, Ningning Li, 2016, Experimental cell research.

A highland-adaptation mutation of the Epas1 protein increases its stability and disrupts the circadian clock in the plateau pika.

Wei Wang, Weiqi Wang, C. Chen, 2022, Cell reports.

Bud specific N-sulfation of heparan sulfate regulates Shp2-dependent FGF signaling during lacrimal gland induction

J. Esko, G. Feng, E. E. Zhang, 2007, Development.

Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism.

G. Feng, E. E. Zhang, K. Hagihara, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Deletion of Shp2 in the Brain Leads to Defective Proliferation and Differentiation in Neural Stem Cells and Early Postnatal Lethality

T. Curran, R. Klein, G. Feng, 2007, Molecular and Cellular Biology.

Shp2 acts downstream of SDF-1alpha/CXCR4 in guiding granule cell migration during cerebellar development.

Y. Rao, G. Feng, E. E. Zhang, 2009, Developmental biology.

Shp2 Is Dispensable in the Formation and Maintenance of the Neuromuscular Junction

T. Gao, L. Mei, G. Feng, 2006, Neurosignals.

The Shp-2 tyrosine phosphatase

G. Feng, E. E. Zhang, L. Lai, 2004 .

Effects of propofol on mammalian central and peripheral circadian clocks

E. E. Zhang, Xi-wen Zhu, Ziqing Yu, 2019 .

Diurnal oscillations of endogenous H2O2 sustained by p66Shc regulate circadian clocks

Kate S. Carroll, De-Pei Liu, Y. Zhang, 2019, Nature Cell Biology.

Identification of Shp-2 as a Stat5A Phosphatase*

G. Feng, E. E. Zhang, Yuhong Chen, 2003, The Journal of Biological Chemistry.

Reciprocal Regulation between the Circadian Clock and Hypoxia Signaling at the Genome Level in Mammals.

E. E. Zhang, Huanwei Huang, Xiangbing Qi, 2017, Cell metabolism.

Redundant Function of REV-ERBα and β and Non-Essential Role for Bmal1 Cycling in Transcriptional Regulation of Intracellular Circadian Rhythms

Steve A. Kay, David K. Welsh, D. Welsh, 2008, PLoS genetics.

Concerted Functions of Gab1 and Shp2 in Liver Regeneration and Hepatoprotection

N. Droin, Jing-Jue Yuan, G. Feng, 2006, Molecular and Cellular Biology.

Deletion of Gab1 in the liver leads to enhanced glucose tolerance and improved hepatic insulin action

A. Hevener, J. Olefsky, G. Feng, 2005, Nature Medicine.

High-Throughput Chemical Screen Identifies a Novel Potent Modulator of Cellular Circadian Rhythms and Reveals CKIα as a Clock Regulatory Kinase

Peter G. Schultz, Eric C. Peters, Steve A. Kay, 2010, PLoS biology.

Cryptochrome Mediates Circadian Regulation of cAMP Signaling and Hepatic Gluconeogenesis

Dmitri A. Nusinow, T. Hirota, Pagkapol Y. Pongsawakul, 2010, Nature Medicine.

Reciprocal Regulation bet ween the Circadian Clock and Hypoxia Signaling at the Genome Level in Mammals Graphical

E. E. Zhang, Huanwei Huang, Xiangbing Qi, 2022 .

Visualizing the Ensemble Structures of Protein Complexes Using Chemical Cross-Linking Coupled with Mass Spectrometry

Chun Tang, Zhou Gong, Meng-Qiu Dong, 2015, Biophysics reports.

Guidelines for Genome-Scale Analysis of Biological Rhythms

Pierre Baldi, Andrew J. Millar, Francis J. Doyle, 2017, Journal of biological rhythms.

Conditional Deletion of Shp2 Tyrosine Phosphatase in Thymocytes Suppresses Both Pre-TCR and TCR Signals1

G. Feng, E. E. Zhang, Y. Ke, 2006, The Journal of Immunology.

Methylation-mediated miR-155-FAM133A axis contributes to the attenuated invasion and migration of IDH mutant gliomas.

S. Xia, E. E. Zhang, S. Lv, 2018, Cancer letters.

Pyrrolidine dithiocarbamate sensitizes U251 brain glioma cells to temozolomide via downregulation of MGMT and BCL-XL

Hui Yang, E. E. Zhang, S. Lv, 2017, Oncology letters.

Development of diabesity in mice with neuronal deletion of Shp2 tyrosine phosphatase.

S. Krajewski, M. Krajewska, M. Scadeng, 2008, The American journal of pathology.

The pancreatic clock is a key determinant of pancreatic fibrosis progression and exocrine dysfunction

Jiaying Shen, E. E. Zhang, Weiliang Jiang, 2022, Science Translational Medicine.

Long-term in vivo recording of circadian rhythms in brains of freely moving mice

D. Welsh, E. E. Zhang, Xiaohua Lv, 2018, Proceedings of the National Academy of Sciences.

The MiR-135b–BMAL1–YY1 loop disturbs pancreatic clockwork to promote tumourigenesis and chemoresistance

Senlin Zhao, Yun Feng, E. E. Zhang, 2018, Cell Death & Disease.

Pre-TCR and TCR Signals Phosphatase in Thymocytes Suppresses Both Conditional Deletion of Shp 2 Tyrosine

E. E. Zhang, Y. Ke, Feng, 2006 .

In Vivo Monitoring of Circadian Clock Gene Expression in the Mouse Suprachiasmatic Nucleus Using Fluorescence Reporters.

E. E. Zhang, Long Mei, Cheng Zhan, 2018, Journal of visualized experiments : JoVE.

Orexin signaling regulates both the hippocampal clock and the circadian oscillation of Alzheimer’s disease-risk genes

E. E. Zhang, Weiliang Jiang, Zhixiong Ma, 2016, Scientific Reports.

Conditional Deletion of Shp2 in the Mammary Gland Leads to Impaired Lobulo-alveolar Outgrowth and Attenuated Stat5 Activation*

W. Muller, G. Feng, E. E. Zhang, 2006, Journal of Biological Chemistry.

A signalling pathway for transcriptional regulation of sleep amount in mice

T. Cai, E. E. Zhang, Hiromasa Funato, 2022, Nature.

Chemical perturbations reveal that RUVBL2 regulates the circadian phase in mammals

L. Lai, J. Takahashi, Chao Tang, 2020, Science Translational Medicine.

Emergence of Noise-Induced Oscillations in the Central Circadian Pacemaker

Daniel B. Forger, Steve A. Kay, Joseph S. Takahashi, 2010, PLoS biology.

Correction: Emergence of Noise-Induced Oscillations in the Central Circadian Pacemaker

D. Welsh, S. Kay, J. Takahashi, 2010, PLoS Biology.

The ratio of intracellular CRY proteins determines the clock period length.

E. E. Zhang, Yang Li, Wei Xiong, 2016, Biochemical and biophysical research communications.

Antitumor efficiency of the cytosine deaminase/5-fluorocytosine suicide gene therapy system on malignant gliomas: an in vivo study.

Hui Yang, E. E. Zhang, S. Lv, 2009, Medical science monitor : international medical journal of experimental and clinical research.

Go Human! Circadian translational medicine has come of age

E. E. Zhang, D. Ju, 2020, Brain Science Advances.

Identification of PCBP1 as a Novel Modulator of Mammalian Circadian Clock

E. E. Zhang, Haijiao Zhao, Na Liu, 2021, Frontiers in Genetics.

The MiR-135b–BMAL1–YY1 loop disturbs pancreatic clockwork to promote tumourigenesis and chemoresistance

Senlin Zhao, Yun Feng, E. E. Zhang, 2018, Cell Death & Disease.

Emergence of Noise-Induced Oscillations in the Central Circadian Pacemaker

Daniel B. Forger, D. Welsh, S. Kay, 2010, PLoS biology.