J. Naranjo

发表

Day-Night Changes in Downstream Regulatory Element Antagonist Modulator/Potassium Channel Interacting Protein Activity Contribute to Circadian Gene Expression in Pineal Gland

T. Madsen, J. Albar, W. Link, 2004, The Journal of Neuroscience.

Inhibition of DREAM-ATF6 interaction delays onset of cognition deficit in a mouse model of Huntington’s disease

B. Mellström, J. Naranjo, Alejandro López-Hurtado, 2018, Molecular Brain.

Neuronal Ca2+ dyshomeostasis in Huntington disease

J. Oliveros, M. Giacomello, J. Naranjo, 2013, Prion.

Specific cytoarchitectureal changes in hippocampal subareas in daDREAM mice

J. Jefferys, M. Zhuo, J. DeFelipe, 2016, Molecular Brain.

Identification of IQM-266, a Novel DREAM Ligand That Modulates KV4 Currents

M. Martín-Martínez, J. Naranjo, Alejandro López-Hurtado, 2019, Front. Mol. Neurosci..

Ca2+-activated Nucleotidase 1, a Novel Target Gene for the Transcriptional Repressor DREAM (Downstream Regulatory Element Antagonist Modulator), Is Involved in Protein Folding and Degradation*

M. Brini, B. Mellström, J. Naranjo, 2012, The Journal of Biological Chemistry.

Gas1 Is Induced during and Participates in Excitotoxic Neuronal Death

B. Mellström, J. Naranjo, V. Ceña, 2002, Molecular and Cellular Neuroscience.

Glial-specific retrovirally mediated gas1 gene expression induces glioma cell apoptosis and inhibits tumor growth in vivo

B. Mellström, J. Naranjo, J. Segovia, 2004, Neurobiology of Disease.

A. Valencia, A. Rojas, L. Sánchez-Pulido, 2006, Journal of Biological Chemistry.

Induction of Glycerol Phosphate Dehydrogenase Gene Expression During Seizure and Analgesia

Dietmar Kuhl, G. Kauselmann, W. Link, 2000, Journal of neurochemistry.

Metamizol potentiates morphine effects on visceral pain and evoked c-Fos immunoreactivity in spinal cord.

I. Fernaud, J. Taylor, B. Mellström, 1998, European journal of pharmacology.

Searching for a Role of NCX/NCKX Exchangers in Neurodegeneration

B. Mellström, J. Naranjo, R. Gómez-Villafuertes, 2007, Molecular Neurobiology.

Uncoupled changes in the expression of the jun family members during myeloid cell differentiation.

F. Mollinedo, J. Naranjo, 1991, European journal of biochemistry.

Increased spinal cord dynorphin mRNA during peripheral inflammation.

M. Iadarola, O. Civelli, J. Naranjo, 1986, NIDA research monograph.

Inhibition of the Neuronal Calcium Sensor DREAM Modulates Presenilin-2 Endoproteolysis

B. Mellström, J. Naranjo, Alejandro López-Hurtado, 2018, Front. Mol. Neurosci..

Targeting the neuronal calcium sensor DREAM with small-molecules for Huntington’s disease treatment

M. Martín-Martínez, B. Mellström, J. Naranjo, 2019, Scientific Reports.

Redox signaling regulates transcriptional activity of the Ca2+-dependent repressor DREAM.

B. Mellström, J. Naranjo, M. Rivas, 2011, Antioxidants & redox signaling.

Human brain synembryn interacts with Gsα and Gqα and is translocated to the plasma membrane in response to isoproterenol and carbachol

M. Montecino, J. Naranjo, L. Guzmán, 2003 .

Reduced Mid1 Expression and Delayed Neuromotor Development in daDREAM Transgenic Mice

M. Dierssen, J. Oliveros, A. Gutiérrez-Adán, 2012, Front. Mol. Neurosci..

Expression of c-jun, jun B and jun D proto-oncogenes in human peripheral-blood granulocytes.

F. Mollinedo, J. Naranjo, M. J. Vaquerizo, 1991, The Biochemical journal.

Differential effect of thyroid hormone on NGFI-A gene expression in developing rat brain.

B. Mellström, J. Naranjo, A. Pérez-Castillo, 1994, Endocrinology.

Synthesis and analgesic properties of N-phosphorylated derivatives of Phe-Ala and Phe-Gly.

M. García-López, J. Naranjo, R. Herranz, 2009, International journal of peptide and protein research.

KChIP3 coupled to Ca2+ oscillations exerts a tonic brake on baseline mucin release in the colon

V. Malhotra, N. Brouwers, M. Valverde, 2018, eLife.

Experimental Brain Glioma: Growth Arrest and Destruction By a Blood-Group-Related Tetrasaccharide

M. Nieto‐Sampedro, J. Naranjo, A. Fernández-Mayoralas, 1996, Journal of neuropathology and experimental neurology.

Neuronotrophic Activity in Adrenal Glands: Effect of Denervation

E. Costa, J. Naranjo, I. Mocchetti, 1987 .

Independent Expression of the α and β c-erbA Genes in Developing Rat Brain

J. Bernal, B. Mellström, J. Naranjo, 1991 .

Ig Production in DREAM Transgenic Mice Increased B Cell Proliferation and Reduced

E. Pinaud, M. Savignac, B. Mellström, 2010 .

The BDNF gene: exemplifying complexity in Ca2+ -dependent gene expression.

W. Link, Begoña Torres, J. Naranjo, 2004, Critical reviews in neurobiology.

Protein-Protein Interactions: Gene Acronym Redundancies and Current Limitations Precluding Automated Data Integration

R. Matthiesen, J. Naranjo, J. Casado-Vela, 2013, Proteomes.

The DREAM protein is associated with thyroid enlargement and nodular development.

M. Zannini, Begoña Torres, B. Mellström, 2009, Molecular endocrinology.

Development The DREAM Protein Is Associated with Thyroid Enlargement and Nodular

Begoña Torres, J. Naranjo, D. Terracciano, 2009 .

Split Personality of Transcription Factors Inside and Outside the Nuclear Border

B. Mellström, J. Naranjo, 2007, Science's STKE.

Transcriptional Repressor DREAM Interacts with Thyroid Transcription Factor-1 and Regulates Thyroglobulin Gene Expression*

P. Santisteban, B. Mellström, J. Naranjo, 2004, Journal of Biological Chemistry.

Molecular pathways of pain: Fos/Jun-mediated activation of a noncanonical AP-1 site in the prodynorphin gene

B. Mellström, J. Naranjo, M. Achaval, 1991, Neuron.

Protein Kinase A-Dependent Derepression of the Human Prodynorphin Gene via Differential Binding to an Intragenic Silencer Element

B. Mellström, J. Naranjo, Á. M. Carrión, 1998, Molecular and Cellular Biology.

Mechanisms of Ca2+-dependent transcription

Britt Mellström, B. Mellström, J. Naranjo, 2001, Current Opinion in Neurobiology.

Unusual c-fos induction upon chromaffin PC12 differentiation by sodium butyrate: loss of fos autoregulatory function.

J. Auwerx, P. Sassone-Corsi, F. Mollinedo, 1990, Nucleic acids research.

Diffusion nuclear magnetic resonance spectroscopy detects substoichiometric concentrations of small molecules in protein samples.

F. Cañada, H. Gabius, M. Palczewska, 2010, Analytical biochemistry.

Evidence for a central but not adrenal, opioid mediation in hypertension induced by brief isolation in the rat.

M. C. Urdin, J. Borrell, J. Naranjo, 1986, Life sciences.

Opioid involvement in hypertension induced by short-term isolation.

J. Borrell, J. Naranjo, J. Fuentes, 1984, Clinical and experimental hypertension. Part A, Theory and practice.

Independent expression of the alpha and beta c-erbA genes in developing rat brain.

J. Bernal, B. Mellström, J. Naranjo, 1991, Molecular endocrinology.

Permissive effect of dexamethasone on the increase of proenkephalin mRNA induced by depolarization of chromaffin cells.

J. P. Schwartz, E. Costa, J. Naranjo, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Stimulus‐Specific Hierarchy of Enhancer Elements Within the Rat Prodynorphin Promoter

B. Mellström, J. Naranjo, S. Luckman, 1998, Journal of neurochemistry.

Changes in the dynamic state of brain proenkephalin‐derived peptides during amygdaloid kindling

E. Costa, J. Naranjo, J. Naranjo, 1986, Journal of Neuroscience Research.

DREAM (Downstream Regulatory Element Antagonist Modulator) contributes to synaptic depression and contextual fear memory

M. Zhuo, Hansen Wang, M. Ren, 2010, Molecular Brain.

DREAM is a Ca2+-regulated transcriptional repressor

Britt Mellström, W. Link, F. Ledo, 1999, Nature.

Negative feedback regulation of the content of proenkephalin MRNA in chromaffin cell cultures

E. Costa, J. Naranjo, B. C. Wise, 1988, Neuropharmacology.

Downstream Regulatory Element Antagonist Modulator Regulates Ca2+ Homeostasis and Viability in Cerebellar Neurons

A. Gutiérrez-Adán, B. Pintado, Begoña Torres, 2005, The Journal of Neuroscience.

Molecular Downstream Regulatory Element Antagonist Modulator Regulates Ca 2 Homeostasis and Viability in Cerebellar Neurons

A. Gutiérrez-Adán, B. Pintado, Begoña Torres, 2005 .

Kindling enhances the stimulation of inositol phospholipid hydrolysis elicited by ibotenic acid in rat hippocampal slices

E. Costa, F. Nicoletti, J. Naranjo, 1986, Brain Research.

Functional N‐methyl‐D‐aspartate receptors in clonal rat phaeochromocytoma cells.

B. Mellström, J. Naranjo, M. Casado, 1996, The Journal of physiology.

Substance P-induced release of Met5-Enkephalin from striatal and periaqueductal gray slices

E. Costa, J. Naranjo, H. Y. Yang, 1983, Brain Research.

Analgesic activity of substance P in rats: tolerance and cross-tolerance with enkephalin.

J. Naranjo, M. P. Fernandez-Tome, J. del Río, 1984, European journal of pharmacology.

Tissue-nonspecific Alkaline Phosphatase Promotes the Neurotoxicity Effect of Extracellular Tau*

J. Ávila, J. Naranjo, R. Gómez-Villafuertes, 2010, The Journal of Biological Chemistry.

VIP Gene Expression in Rat Thymus and Spleen

M. Delgado, J. Leceta, R. Gomariz, 1993, Brain, Behavior, and Immunity.

DREAM Mediated Regulation of GCM1 in the Human Placental Trophoblast

J. Kingdom, S. Lye, J. Naranjo, 2013, PloS one.

Antinociceptive and Met-enkephalin releasing effects of tachykinins and substance P fragments

J. Naranjo, J. Rı́o, A. Arnedo, 1986, Peptides.

Differential activation of spinal cord dynorphin and enkephalin neurons during hyperalgesia: evidence using cDNA hybridization

M. Iadarola, O. Civelli, J. Naranjo, 1988, Brain Research.

Analgesic activity of substance P in rats: apparent mediation by met-enkephalin release.

J. Naranjo, F. Sánchez‐Franco, J. Garzón, 1982, Life sciences.

Blockade by met-enkephalin antiserum of analgesia induced by substance p in mice

J. Naranjo, F. Sánchez‐Franco, J. Rı́o, 1982, Neuropharmacology.

Association between hypoalgesia and hypertension in rats after short-term isolation

J. Naranjo, J. Naranjo, J. Fuentes, 1985, Neuropharmacology.

Locomotor activation induced in rodents by substance P and analogues Blockade of the effect of substance P by met-enkephalin antiserum

J. Naranjo, J. Rı́o, 1984, Neuropharmacology.

Molecular mechanisms of pain: Serotonin1A receptor agonists trigger transactivation by c-fos of the prodynorphin gene in spinal cord neurons

M. Colado, J. Lucas, B. Mellström, 1993, Neuron.

Expression of cholecystokinin and enkephalin mRNA in discrete brain regions

M. Iadarola, A. Duchemin, J. Naranjo, 1989, Peptides.

Differential effects of D-Ala2 analogues of enkephalins on substance P-induced analgesia in rodents.

J. Naranjo, J. del Río, 1982, European journal of pharmacology.

Regulators of A20 (TNFAIP3): new drug-able targets in inflammation.

B. Lambrecht, J. Naranjo, B. Schock, 2019, American journal of physiology. Lung cellular and molecular physiology.

Transcriptionally mediated gene targeting of gas1 to glioma cells elicits growth arrest and apoptosis

J. Naranjo, J. Segovia, P. Vergara, 2003, Journal of neuroscience research.

Ca2+-dependent Transcriptional Control of Ca2+ Homeostasis*

B. Mellström, J. Naranjo, 2012, The Journal of Biological Chemistry.

Ca 2-dependent Transcriptional Control of Ca 2 Homeostasis *

B. Mellström, J. Naranjo, 2012 .

Ca2+-operated transcriptional networks: molecular mechanisms and in vivo models.

M. Savignac, B. Mellström, J. Naranjo, 2008, Physiological reviews.

Ca 2-Operated Transcriptional Networks : Molecular Mechanisms and In Vivo Models

M. Savignac, B. Mellström, J. Naranjo, 2008 .

G Protein-coupled Receptor Kinase 2-mediated Phosphorylation of Downstream Regulatory Element Antagonist Modulator Regulates Membrane Trafficking of Kv4.2 Potassium Channel*

M. Savignac, B. Mellström, J. Naranjo, 2007, Journal of Biological Chemistry.

Hypotensive effect of naloxone on high blood pressure induced by stress in the rat.

M. C. Urdin, J. Naranjo, J. Fuentes, 1987, Life sciences.

Thyroid hormones, learning and memory

J. Naranjo, M. Rivas, 2007, Genes, brain, and behavior.

Transcriptional repressor DREAM regulates T‐lymphocyte proliferation and cytokine gene expression

A. Gutiérrez-Adán, B. Pintado, M. Palczewska, 2005, The EMBO journal.

Ca2+‐dependent block of CREB–CBP transcription by repressor DREAM

F. Ledo, B. Mellström, J. Naranjo, 2002, The EMBO journal.

Interleukin 3‐dependent activation of DREAM is involved in transcriptional silencing of the apoptotic hrk gene in hematopoietic progenitor cells

W. Link, J. Naranjo, J. Fernández-Luna, 2001, The EMBO journal.

A neuroprotective phase precedes striatal degeneration upon nucleolar stress

B. Liss, L. Bonfanti, I. Grummt, 2013, Cell Death and Differentiation.

Nuclear fos domains in transcriptionally activated supraoptic nucleus neurons

M. Berciano, J. Naranjo, M. Lafarga, 1993, Neuroscience.

Mechanisms of Ca(2+)-dependent transcription.

B. Mellström, J. Naranjo, 2001, Current opinion in neurobiology.

The repressor DREAM acts as a transcriptional activator on Vitamin D and retinoic acid response elements

A. Aranda, M. Savignac, B. Mellström, 2005, Nucleic acids research.

Calcium-dependent transcription of cytokine genes in T lymphocytes

M. Savignac, B. Mellström, J. Naranjo, 2007, Pflügers Archiv - European Journal of Physiology.

Human brain synembryn interacts with Gsalpha and Gqalpha and is translocated to the plasma membrane in response to isoproterenol and carbachol.

M. Montecino, J. Naranjo, L. Guzmán, 2003, Journal of cellular physiology.

PC12 cells differentiate into chromaffin cell-like phenotype in coculture with adrenal medullary endothelial cells.

H. Pollard, P. Lelkes, J. Naranjo, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Activating transcription factor 6 derepression mediates neuroprotection in Huntington disease.

J. Oliveros, D. Villar, B. Mellström, 2016, The Journal of clinical investigation.

Differences in expression of transcription factor AP-1 in human promyelocytic HL-60 cells during differentiation towards macrophages versus granulocytes.

F. Mollinedo, C. Gajate, Antonio Tugores, 1993, The Biochemical journal.

The DREAM-DRE interaction: key nucleotides and dominant negative mutants.

W. Link, F. Ledo, B. Mellström, 2000, Biochimica et biophysica acta.

Transient expression of c-fos during the development of the rat cerebral cortex.

A. Fairén, B. Mellström, J. Naranjo, 1991, Brain research. Developmental brain research.

Inhibition of DREAM-ATF6 interaction delays onset of cognition deficit in a mouse model of Huntington’s disease

B. Mellström, J. Naranjo, Alejandro López-Hurtado, 2018, Molecular Brain.

Fos-like expression and nuclear size in osmotically stimulated supraoptic nucleus neurons

M. Berciano, J. Naranjo, M. Lafarga, 1992, Neuroscience.

Targeting the neuronal calcium sensor DREAM with small-molecules for Huntington’s disease treatment

M. Martín-Martínez, B. Mellström, J. Naranjo, 2019, Scientific Reports.

Specific cytoarchitectureal changes in hippocampal subareas in daDREAM mice

M. Zhuo, J. DeFelipe, B. Mellström, 2016, Molecular Brain.

DREAM Controls the On/Off Switch of Specific Activity-Dependent Transcription Pathways

M. Zhuo, J. DeFelipe, M. Dierssen, 2013, Molecular and Cellular Biology.

DREAM-αCREM Interaction via Leucine-Charged Domains Derepresses Downstream Regulatory Element-Dependent Transcription

W. Link, F. Ledo, B. Mellström, 2000, Molecular and Cellular Biology.

Transcriptional response to cAMP in brain: Specific distribution and induction of CREM antagonists

P. Sassone-Corsi, N. Foulkes, B. Mellström, 1993, Neuron.

Functional kainate-selective glutamate receptors in cultured hippocampal neurons.

B. Mellström, J. Naranjo, J. Lerma, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Proenkephalin gene expression in the PC12 pheochromocytoma cell line: stimulation by sodium butyrate.

J. Byrd, I. Lindberg, J. Naranjo, 1987, Endocrinology.

Regulation of striatal enkephalin turnover in rats receiving antagonists of specific dopamine receptor subtypes.

E. Costa, J. Naranjo, I. Mocchetti, 1987, The Journal of pharmacology and experimental therapeutics.

Extraction of peptides from guanidine thiocyanate homogenates used to isolate RNA

M. Iadarola, J. Naranjo, 1988, Peptides.

β-Endorphin: A common factor in the antihypertensive action of clonidine-type imidazolines in spontaneously hypertensive rats

M. C. Urdin, J. Naranjo, J. Fuentes, 1985 .

Identification and Functional Characterization of a K+ Channel α-Subunit with Regulatory Properties Specific to Brain

J. López-Barneo, B. Mellström, J. Naranjo, 1997, The Journal of Neuroscience.

Antinociceptive effects in rodents of the dipeptide Lys-Trp (Nps) and related compounds

M. García-López, R. González-Muñiz, J. Naranjo, 1986, Peptides.

Ca2+-dependent transcriptional repression and derepression: DREAM, a direct effector.

B. Mellström, J. Naranjo, 2001, Seminars in cell & developmental biology.

Increased B Cell Proliferation and Reduced Ig Production in DREAM Transgenic Mice

E. Pinaud, J. Oliveros, M. Savignac, 2010, The Journal of Immunology.

Co-induction of jun B and c-fos in a subset of neurons in the spinal cord.

J. Lucas, P. Sassone-Corsi, B. Mellström, 1991, Oncogene.

Differential expression of the jun family members in rat brain.

P. Sassone-Corsi, B. Mellström, J. Naranjo, 1991, Oncogene.

IQM-PC332, a Novel DREAM Ligand with Antinociceptive Effect on Peripheral Nerve Injury-Induced Pain

J. Naranjo, M. Gutiérrez-Rodríguez, M. V. Barahona, 2022, International journal of molecular sciences.

Sumoylation regulates nuclear localization of repressor DREAM.

A. Valencia, A. Rojas, M. Palczewska, 2011, Biochimica et biophysica acta.

Increase in spinal cord dynorphin biosynthesis during peripheral inflammation: Behavioral, neuropeptide and mRNA studies

M. Iadarola, J. Naranjo, C. M. Flores, 1987, PAIN.

Activation of DREAM (Downstream Regulatory Element Antagonistic Modulator), a Calcium-Binding Protein, Reduces L-DOPA-Induced Dyskinesias in Mice

R. Moratalla, J. Naranjo, M. Vallejo, 2015, Biological Psychiatry.

Narine occlusion decreases basal levels of fos protein in the cerebral cortex of the lizard Podarcis hispanica

B. Mellström, J. Naranjo, C. López-García, 1992, Neuroscience.

Kcnip1 a Ca²⁺-dependent transcriptional repressor regulates the size of the neural plate in Xenopus.

B. Mellström, J. Naranjo, I. Néant, 2015, Biochimica et biophysica acta.

Activation of DREAM , a calcium-binding protein , reduces L-DOPA-induced dyskinesias in mice

R. Moratalla, J. Naranjo, M. Vallejo, 2017 .

Ca2+-dependent prodynorphin transcriptional derepression in neuroblastoma cells is exerted through DREAM protein activity in a kinase-independent manner

J. Naranjo, L. Jiménez‐Díaz, Á. M. Carrión, 2003, Molecular and Cellular Neuroscience.

Seizure-mediated neuronal activation induces DREAM gene expression in the mouse brain.

K. Mikoshiba, Y. Konishi, J. Naranjo, 2002, Brain research. Molecular brain research.

L. Sánchez-Pulido, B. Mellström, J. Naranjo, 2006 .

Involvement of spinal monoaminergic pathways in antinociception produced by substance P and neurotensin in rodents

J. Naranjo, J. Rı́o, A. Arnedo, 1989, Neuropharmacology.

Dopaminergic regulation of olfactory type G‐protein α subunit expression in the striatum

R. Moratalla, D. Hervé, J. Naranjo, 2015, Movement disorders : official journal of the Movement Disorder Society.

Nuclear Oncogenes as Transcription Factors

J. Auwerx, P. Sassone-Corsi, N. Foulkes, 1991 .

Transcriptional repressor DREAM regulates trigeminal noxious perception

J. Oliveros, M. Palczewska, J. Naranjo, 2017, Journal of neurochemistry.

Building the DREAM interactome

D. Villar, J. Naranjo, Xosé M. Dopazo, 2011, Science China Life Sciences.

Roles of CREB in the regulation of FMRP by group I metabotropic glutamate receptors in cingulate cortex

M. Zhuo, S. Kida, Hansen Wang, 2012, Molecular Brain.

Calcium in the Regulation of Gene Expression

J. Naranjo, M. Rivas, 2013 .

Expression of the prodynorphin gene in the developing and adult cerebral cortex of the rat: An in situ hybridization study

A. Fairén, G. Alvarez-Bolado, J. Naranjo, 1990, The Journal of comparative neurology.

DREAM regulates BDNF-dependent spinal sensitization

C. Avendaño, J. Lopez-Garcia, Begoña Torres, 2010, Molecular pain.