A. Matsushima

发表

Structural Analysis and Identification of Novel Isoforms of the Circadian Clock Gene period in the Silk Moth Bombyx mori

Y. Chuman, Y. Shimohigashi, Y. Takeda, 2004, Zoological science.

ERRgamma tethers strongly bisphenol A and 4-alpha-cumylphenol in an induced-fit manner.

Y. Shimohigashi, A. Matsushima, T. Teramoto, 2008, Biochemical and biophysical research communications.

A Characteristic Back Support Structure in the Bisphenol A-Binding Pocket in the Human Nuclear Receptor ERRγ

Y. Shimohigashi, A. Matsushima, M. Shimohigashi, 2014, PloS one.

Receptor binding characteristics of the endocrine disruptor bisphenol A for the human nuclear estrogen‐related receptor γ

Y. Shimohigashi, A. Matsushima, Hiroyuki Okada, 2007, The FEBS journal.

Tritium-labelled isovaleryl-RYYRIK-NH2 as potential antagonist probe for ORL1 nociceptin receptor.

H. Nishimura, Y. Shimohigashi, A. Matsushima, 2014, Bioorganic & medicinal chemistry.

Capturing of the free cysteine residue in the ligand-binding site by affinity labeling of the ORL1 nociceptin receptor.

H. Nishimura, Y. Shimohigashi, A. Matsushima, 2011, Bioorganic & medicinal chemistry.

Spare interactions of highly potent [Arg(14),Lys(15)]nociceptin for cooperative induction of ORL1 receptor activation.

H. Nishimura, Y. Shimohigashi, K. Okada, 2009, Bioorganic & medicinal chemistry.

Discriminatory synergistic effect of Trp-substitutions in superagonist [(Arg/Lys)(14), (Arg/Lys)(15)]nociceptin on ORL1 receptor binding and activation.

H. Nishimura, Y. Shimohigashi, K. Okada, 2009, Bioorganic & medicinal chemistry.

Designed modification of partial agonist of ORL1 nociceptin receptor for conversion into highly potent antagonist.

Y. Shimohigashi, K. Okada, A. Matsushima, 2008, Bioorganic & medicinal chemistry.

Synergistic effect of basic residues at positions 14-15 of nociceptin on binding affinity and receptor activation.

Y. Shimohigashi, K. Okada, A. Matsushima, 2008, Bioorganic & medicinal chemistry.

Endocrine disruptor bisphenol A strongly binds to human estrogen-related receptor gamma (ERRgamma) with high constitutive activity.

Y. Shimohigashi, A. Matsushima, Hiroyuki Okada, 2006, Toxicology letters.

Placenta expressing the greatest quantity of bisphenol A receptor ERR{gamma} among the human reproductive tissues: Predominant expression of type-1 ERRgamma isoform.

Y. Shimohigashi, Y. Takeda, A. Matsushima, 2009, Journal of biochemistry.

Structural evidence for endocrine disruptor bisphenol A binding to human nuclear receptor ERR gamma.

M. Kimura, Y. Shimohigashi, S. Kawabata, 2007, Journal of biochemistry.

Molecular cloning and circadian expression profile of insect neuropeptide PDF in black blowfly, Phormia regina

Y. Chuman, Y. Shimohigashi, Y. Takeda, 2003, Letters in Peptide Science.

Bisphenol AF Is a Full Agonist for the Estrogen Receptor ERα but a Highly Specific Antagonist for ERβ

Y. Shimohigashi, A. Matsushima, M. Shimohigashi, 2010, Environmental health perspectives.

Endocrine Disrupter Bisphenol A Increases In Situ Estrogen Production in the Mouse Urogenital Sinus1

K. Igarashi, J. Kanno, Y. Shimohigashi, 2011, Biology of reproduction.

Placenta Expressing the Greatest Quantity of Bisphenol A Receptor ERR c among the Human Reproductive Tissues : Predominant Expression of Type-1 ERR c Isoform

Y. Shimohigashi, Y. Takeda, A. Matsushima, 2009 .

A strategy to explore the target receptor of endocrine disruptors: Estrogen-related receptor γ (ERRγ) as a genuine acceptor of Bisphenol A

Y. Shimohigashi, A. Matsushima, 2008 .

Edge-to-face CH/pi interaction between ligand Phe-phenyl and receptor aromatic group in the thrombin receptor activation.

Y. Shimohigashi, A. Matsushima, T. Nose, 2000, Journal of biochemistry.

Alanine scanning and characterization of core peptides in Scombridae fish family for construction of Kiss1 super analog.

A. Matsushima, K. Ohta, M. Matsuyama, 2019, General and comparative endocrinology.

N-methylthioacetylation of RYYRIK-NH2 with enhanced specific binding affinity and high antagonist activity for nociceptin ORL1 receptor.

H. Nishimura, Y. Shimohigashi, A. Matsushima, 2014, Bioorganic & medicinal chemistry.

Direct Evidence Revealing Structural Elements Essential for the High Binding Ability of Bisphenol A to Human Estrogen-Related Receptor-γ

Y. Shimohigashi, A. Matsushima, Hiroyuki Okada, 2007, Environmental health perspectives.

A Circadian Neuropeptide, Pigment-Dispersing Factor–PDF, in the Last-Summer Cicada Meimuna opalifera: cDNA Cloning and Immunocytochemistry

Y. Chuman, Y. Shimohigashi, A. Matsushima, 2002, Zoological science.

Double-labelled in situ hybridization reveals the lack of co-localization of mRNAs for the circadian neuropeptide PDF and FMRFamide in brains of the flies Musca domestica and Drosophila melanogaster.

Y. Shimohigashi, Y. Takeda, A. Matsushima, 2007, Journal of biochemistry.

Structural isoforms of the circadian neuropeptide PDF expressed in the optic lobes of the cricket Gryllus bimaculatus: Immunocytochemical evidence from specific monoclonal antibodies

I. Meinertzhagen, K. Sakaguchi, Y. Chuman, 2006, The Journal of comparative neurology.

Molecular cloning and circadian expression profile of insect neuropeptide PDF in black blowfly,Phormia regina

Y. Chuman, Y. Shimohigashi, Y. Takeda, 2003, Letters in Peptide Science.

Biosynthetic Short Neuropeptides: A Rational Theory Based on Experimental Results for the Missing Pain‐Relief Opioid Endomorphin Precursor Gene

Kanako O. Koyanagi, J. Sese, A. Matsushima, 2019, Chembiochem : a European journal of chemical biology.

A Novel Action of Endocrine-Disrupting Chemicals on Wildlife; DDT and Its Derivatives Have Remained in the Environment

A. Matsushima, 2018, International journal of molecular sciences.

An endocrine disruptor, bisphenol A, affects development in the protochordate Ciona intestinalis: hatching rates and swimming behavior alter in a dose-dependent manner.

I. Meinertzhagen, Y. Shimohigashi, A. Matsushima, 2013, Environmental pollution.

Receptor-binding affinities of bisphenol A and its next-generation analogs for human nuclear receptors.

Y. Shimohigashi, A. Matsushima, M. Shimohigashi, 2019, Toxicology and applied pharmacology.

Pigment-Dispersing Factor Affects Nocturnal Activity Rhythms, Photic Entrainment, and the Free-Running Period of the Circadian Clock in the Cricket Gryllus bimaculatus

Y. Shimohigashi, K. Tomioka, A. Matsushima, 2011, Journal of biological rhythms.

High cytotoxicity of a degraded TBBPA, dibromobisphenol A, through apoptotic and necrosis pathways

A. Matsushima, T. Nose, Keisuke Tomohara, 2023, Heliyon.

α‐Helix‐peptides comprising the human nuclear receptor ERRγ competitively provoke inhibition of functional homomeric dimerization

H. Nishimura, Y. Shimohigashi, A. Matsushima, 2016, Biopolymers.

Distinction of the binding modes for human nuclear receptor ERRgamma between bisphenol A and 4-hydroxytamoxifen.

Y. Shimohigashi, A. Matsushima, Hiroyuki Okada, 2010, Journal of biochemistry.

Endocrine disruptor bisphenol A strongly binds to human estrogen-related receptor γ (ERRγ) with high constitutive activity

Y. Shimohigashi, A. Matsushima, Hiroyuki Okada, 2006 .

Bisphenol A derivatives act as novel coactivator-binding inhibitors for estrogen receptor β

R. Evans, M. Downes, A. Matsushima, 2021, bioRxiv.

Fine spatial assembly for construction of the phenol-binding pocket to capture bisphenol A in the human nuclear receptor estrogen-related receptor γ.

Y. Shimohigashi, A. Matsushima, Xiaohui Liu, 2012, Journal of biochemistry.

Synthesis of a complete set of L-difluorophenylalanines, L-(F2)Phe, as molecular explorers for the CH/π interaction between peptide ligand and receptor

Y. Shimohigashi, K. Okada, N. Shirasu, 2000 .

Evaluation of the influence of halogenation on the binding of bisphenol A to the estrogen-related receptor γ.

A. Matsushima, T. Okubo, Y. Kakuta, 2020, Chemical research in toxicology.

Discovery of novel oestrogen receptor α agonists and antagonists by screening a revisited privileged structure moiety for nuclear receptors

A. Matsushima, Takahiro Masuya, Xiaohui Liu, 2019, Scientific Reports.

Direct evidence of edge-to-face CH/π interaction for PAR-1 thrombin receptor activation

Y. Shimohigashi, A. Matsushima, D. Asai, 2021, Bioorganic & Medicinal Chemistry.

Specific affinity‐labeling of the nociceptin ORL1 receptor using a thiol‐activated Cys(Npys)‐containing peptide ligand

H. Nishimura, Y. Shimohigashi, A. Matsushima, 2016, Biopolymers.