M. Layne

发表

Molecular Mechanisms of Morning Onset of Myocardial Infarction

M. Watanabe, K. Maemura, M. Layne, 2001, Annals of the New York Academy of Sciences.

Down-regulation of Krüppel-like Factor-4 (KLF4) by MicroRNA-143/145 Is Critical for Modulation of Vascular Smooth Muscle Cell Phenotype by Transforming Growth Factor-β and Bone Morphogenetic Protein 4*

B. Davis-Dusenbery, A. Hata, Alexandra S. Weisman, 2011, The Journal of Biological Chemistry.

Actionable Cytopathogenic Host Responses of Human Alveolar Type 2 Cells to SARS-CoV-2

B. Blencowe, A. Emili, S. Wuchty, 2020, Molecular Cell.

A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis

B. Suki, R. Lafyatis, D. Abraham, 2015, PloS one.

Bone Morphogenetic Protein Signaling in Vascular Disease

B. Davis-Dusenbery, A. Hata, M. Layne, 2012, The Journal of Biological Chemistry.

Therapeutic Potential of Heme Oxygenase-1 in Aneurysmal Diseases

A. Orekhov, M. Layne, S. yet, 2020, Antioxidants.

Cardiovascular Basic Helix Loop Helix Factor 1, a Novel Transcriptional Repressor Expressed Preferentially in the Developing and Adult Cardiovascular System*

S. Fukumoto, Masafumi Watanabe, C. Hsieh, 2000, The Journal of Biological Chemistry.

Tumor necrosis factor-alpha and basic fibroblast growth factor differentially inhibit the insulin-like growth factor-I induced expression of myogenin in C2C12 myoblasts.

S. Farmer, M. Layne, 1999, Experimental cell research.

Striated muscle preferentially expressed genes alpha and beta are two serine/threonine protein kinases derived from the same gene as the aortic preferentially expressed gene-1.

S. Fukumoto, C. Hsieh, K. Maemura, 2000, The Journal of biological chemistry.

Thioredoxin Facilitates the Induction of Heme Oxygenase-1 in Response to Inflammatory Mediators*

C. Hsieh, M. Layne, S. yet, 2000, The Journal of Biological Chemistry.

Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice.

L. Kobzik, C. Hsieh, K. Maemura, 1999, The Journal of clinical investigation.

Cardiac-Specific Expression of Heme Oxygenase-1 Protects Against Ischemia and Reperfusion Injury in Transgenic Mice

J. Ingwall, R. Tian, K. Maemura, 2001, Circulation research.

Impaired Abdominal Wall Development and Deficient Wound Healing in Mice Lacking Aortic Carboxypeptidase-Like Protein

C. Hsieh, K. Maemura, M. Layne, 2001, Molecular and Cellular Biology.

Disruption of Striated Preferentially Expressed Gene Locus Leads to Dilated Cardiomyopathy in Mice

R. Liao, P. Anversa, A. Leri, 2009, Circulation.

Absence of heme oxygenase-1 exacerbates myocardial ischemia/reperfusion injury in diabetic mice.

M. Layne, S. yet, D. Peng, 2005, Diabetes.

Adipose Stroma Accelerates the Invasion and Escape of Human Breast Cancer Cells from an Engineered Microtumor

Alex J. Seibel, C. Nelson, J. Tien, 2021, Cellular and Molecular Bioengineering.

Gastroschisis in mice lacking aortic carboxypeptidase-like protein is associated with a defect in neuromuscular development of the eviscerated intestine.

M. Layne, A. Flake, A. Radu, 2010, Pediatric research.

Modulation of cysteine-rich protein 2 expression in vascular injury and atherosclerosis

M. Layne, S. yet, Meng-Ling Wu, 2014, Molecular Biology Reports.

Modulation of the thioredoxin system during inflammatory responses and its effect on heme oxygenase-1 expression.

M. Layne, S. yet, I. Carvajal, 2002, Antioxidants and Redox Signaling.

Aortic carboxypeptidase-like protein is regulated by transforming growth factor beta in 3T3-L1 preadipocytes.

A. Sorisky, M. Layne, A. Gagnon, 2005, Experimental cell research.

Down-regulation of aortic carboxypeptidase-like protein during the early phase of 3T3-L1 adipogenesis.

A. Sorisky, M. Layne, A. Gagnon, 2002, Endocrinology.

Cyclooxygenase‐2 deficient mice are resistant to endotoxin‐induced inflammation and death

B. Levy, M. Layne, S. yet, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Impaired Glucocorticoid Suppression of TGFβ Signaling in Human Omental Adipose Tissues Limits Adipogenesis and May Promote Fibrosis

Yuanyuan Wu, R. T. Pickering, M. Layne, 2018, Diabetes.

Upstream Stimulatory Factors Regulate Aortic Preferentially Expressed Gene-1 Expression in Vascular Smooth Muscle Cells*

M. Watanabe, M. Layne, S. yet, 2001, The Journal of Biological Chemistry.

Animal cell mutants unable to take up biologically active glycerophospholipids.

E. Modest, R. Zoeller, M. Layne, 1995, Journal of lipid research.

Intronic CArG Box Regulates Cysteine-Rich Protein 2 Expression in the Adult but Not in Developing Vasculature

Yi-Chung Lee, M. Layne, S. yet, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Identification of a CArG-independent region of the cysteine-rich protein 2 promoter that directs expression in the developing vasculature.

M. Layne, S. yet, Yen-Hsu Chen, 2003, American journal of physiology. Heart and circulatory physiology.

Embryonic expression suggests an important role for CRP2/SmLIM in the developing cardiovascular system.

R. Maas, E. Haber, N. Sibinga, 1998, Circulation research.

Pre-emptive gene therapy using recombinant adeno-associated virus delivery of extracellular superoxide dismutase protects heart against ischemic reperfusion injury, improves ventricular function and prolongs survival

M. Layne, Lunan Zhang, M. Perrella, 2004, Gene Therapy.

High mobility group A1 protein mediates human nitric oxide synthase 2 gene expression

R. Takamiya, M. Layne, S. yet, 2008, FEBS letters.

Exacerbation of Chronic Renovascular Hypertension and Acute Renal Failure in Heme Oxygenase-1–Deficient Mice

H. Rennke, K. Maemura, M. Layne, 2001, Circulation research.

Lung Atelectasis Promotes Immune and Barrier Dysfunction as Revealed by Transcriptome Sequencing in Female Sheep

K. Grogg, X. Varelas, L. Sholl, 2020, Anesthesiology.

Heme oxygenase 1 in regulation of inflammation and oxidative damage.

M. Layne, S. yet, M. Perrella, 2002, Methods in enzymology.

Reduction of Nitric Oxide Synthase 2 Expression by Distamycin A Improves Survival from Endotoxemia1

M. Layne, Yen-Hsu Chen, R. Okabe, 2004, The Journal of Immunology.

Survival from Endotoxemia Expression by Distamycin A Improves Reduction of Nitric Oxide Synthase 2

M. Layne, Xiaoli Liu, L. Fredenburgh, 2004 .

Cysteine-rich protein 2 deficiency attenuates angiotensin II-induced abdominal aortic aneurysm formation in mice

A. Orekhov, M. Layne, S. yet, 2022, Journal of biomedical science.

Netropsin improves survival from endotoxaemia by disrupting HMGA1 binding to the NOS2 promoter.

M. Grant, M. Layne, A. C. Rigby, 2009, The Biochemical journal.

Endotoxin-Induced Down-Regulation of Elk-3 Facilitates Heme Oxygenase-1 Induction in Macrophages1

M. Layne, S. yet, Yen-Hsu Chen, 2006, The Journal of Immunology.

Induction in Macrophages Elk-3 Facilitates Heme Oxygenase-1 Endotoxin-Induced Down-Regulation of Layne and

M. Layne, S. yet, Yen-Hsu Chen, 2006 .

IFN regulatory factor-1 regulates IFN-gamma-dependent cathepsin S expression.

L. Santambrogio, E. Silverman, M. Layne, 2002, Journal of immunology.

Telomerase, myofibroblasts, and pulmonary fibrosis.

M. Layne, S. Schissel, 2006, American journal of respiratory cell and molecular biology.

Distamycin A Inhibits HMGA1-Binding to the P-Selectin Promoter and Attenuates Lung and Liver Inflammation during Murine Endotoxemia

R. Reeves, U. V. von Andrian, M. Layne, 2010, PLoS ONE.

Frontline Science: Targeted expression of a dominant‐negative high mobility group A1 transgene improves outcome in sepsis

R. Reeves, J. Lederer, M. Layne, 2018, Journal of leukocyte biology.

Aortic carboxypeptidase-like protein is expressed in collagen-rich tissues during mouse embryonic development.

M. Layne, S. yet, M. Perrella, 2005, Gene expression patterns : GEP.

CLIF, a Novel Cycle-like Factor, Regulates the Circadian Oscillation of Plasminogen Activator Inhibitor-1 Gene Expression*

S. M. de la Monte, C. Hsieh, M. Chin, 2000, The Journal of Biological Chemistry.

Aortic carboxypeptidase-like protein regulates vascular adventitial progenitor and fibroblast differentiation through myocardin related transcription factor A

S. Farmer, M. Layne, S. yet, 2021, Scientific Reports.

Mechanisms of aortic carboxypeptidase-like protein secretion and identification of an intracellularly retained variant associated with Ehlers–Danlos syndrome

Michael L. Smith, M. Layne, J. Wong, 2020, The Journal of Biological Chemistry.

Aortic carboxypeptidase-like protein enhances adipose tissue stromal progenitor differentiation into myofibroblasts and is upregulated in fibrotic white adipose tissue

S. Farmer, M. Layne, S. Fried, 2018, PloS one.

Bi-allelic Alterations in AEBP1 Lead to Defective Collagen Assembly and Connective Tissue Structure Resulting in a Variant of Ehlers-Danlos Syndrome.

J. Parisi, F. Alkuraya, N. McDonnell, 2018, American journal of human genetics.

Aortic Carboxypeptidase-like Protein (ACLP) Enhances Lung Myofibroblast Differentiation through Transforming Growth Factor β Receptor-dependent and -independent Pathways*

M. Nugent, M. Layne, Barbara D. Smith, 2013, The Journal of Biological Chemistry.

Adipocyte Enhancer Binding Protein 1 and Aortic Carboxypeptidase-Like Protein

M. Layne, K. Tumelty, 2013 .

Gastroschisis in Mice Lacking Aortic Carboxypeptidase-Like Protein Is Associated With a Defect in Neuromuscular Development of the Eviscerated Intestine

M. Layne, A. Flake, E. Danzer, 2010, Pediatric Research.

Cardiovascular , Pulmonary and Renal Pathology Aortic Carboxypeptidase-Like Protein Is Expressed in Fibrotic Human Lung and its Absence Protects against Bleomycin-Induced Lung Fibrosis

M. Layne, S. Schissel, M. Perrella, 2010 .

Characterization of the Mouse Aortic Carboxypeptidase-Like Protein Promoter Reveals Activity in Differentiated and Dedifferentiated Vascular Smooth Muscle Cells

C. Hsieh, K. Maemura, M. Layne, 2002, Circulation research.

Aortic Carboxypeptidase-like Protein, a Novel Protein with Discoidin and Carboxypeptidase-like Domains, Is Up-regulated during Vascular Smooth Muscle Cell Differentiation*

E. Haber, M. Blanar, C. Hsieh, 1998, The Journal of Biological Chemistry.

Superoxide production by macrophages stimulatedin vivo with synthetic ether lipids

B. Schreiber, E. Modest, M. Layne, 1994, Lipids.

Molecular Cloning, Characterization, and Promoter Analysis of the Mouse Crp2/SmLim Gene

S. Folta, C. Hsieh, M. Chin, 1998, The Journal of Biological Chemistry.

Obesity-induced senescent macrophages activate a fibrotic transcriptional program in adipocyte progenitors

X. Varelas, S. Farmer, M. Layne, 2022, Life Science Alliance.

Akt Participation in the Wnt Signaling Pathway through Dishevelled*

S. Fukumoto, J. Rubin, A. Rosenzweig, 2001, The Journal of Biological Chemistry.

Gene Therapy Strategy for Long-Term Myocardial Protection Using Adeno-Associated Virus-Mediated Delivery of Heme Oxygenase Gene

J. Oyama, A. Mangi, M. Layne, 2002, Circulation.

Adipose Cells Induce Escape from an Engineered Human Breast Microtumor Independently of their Obesity Status

Alex J. Seibel, D. Radisky, C. Nelson, 2022, Cellular and Molecular Bioengineering.

Adipose Stroma Accelerates the Invasion and Escape of Human Breast Cancer Cells from an Engineered Microtumor

Alex J. Seibel, C. Nelson, J. Tien, 2021, Cellular and Molecular Bioengineering.

Striated Muscle Preferentially Expressed Genes α and β Are Two Serine/Threonine Protein Kinases Derived from the Same Gene as the Aortic Preferentially Expressed Gene-1*

S. Fukumoto, C. Hsieh, K. Maemura, 2000, The Journal of Biological Chemistry.

Role of macrophage‐expressed adipocyte fatty acid binding protein in the development of accelerated atherosclerosis in hypercholesterolemic mice

B. Schreiber, Dezheng Zhao, M. Layne, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

S. Farmer, M. Layne, Barbara D. Smith, 2015, Cell.

M. Layne, L. Luchsinger, Barbara D. Smith, 2011, The Journal of Biological Chemistry.

Generation of a Dominant-negative Mutant of Endothelial PAS Domain Protein 1 by Deletion of a Potent C-terminal Transactivation Domain*

C. Hsieh, K. Maemura, M. Layne, 1999, The Journal of Biological Chemistry.

Regulation of Smooth Muscle Cell Differentiation by AT-Rich Interaction Domain Transcription Factors Mrf2&agr; and Mrf2&bgr;

Masafumi Watanabe, C. Hsieh, K. Maemura, 2002 .

IFN Regulatory Factor-1 Regulates IFN-γ-Dependent Cathepsin S Expression1

L. Santambrogio, E. Silverman, M. Layne, 2002, The Journal of Immunology.

Identification of a chronic obstructive pulmonary disease genetic determinant that regulates HHIP.

Edwin K Silverman, Michael H Cho, Craig P Hersh, 2012, Human molecular genetics.

Matrisome changes in Parkinson’s disease

J. Zaia, M. Layne, Rekha Raghunathan, 2022, Analytical and Bioanalytical Chemistry.

Heme oxygenase-1 in environmental toxin-induced lung disease

M. Layne, S. yet, Meng-Ling Wu, 2012, Toxicology mechanisms and methods.

Absence of heme oxygenase‐1 exacerbates atherosclerotic lesion formation and vascular remodeling

N. Sibinga, M. Layne, S. yet, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Transforming Growth Factor β Up-regulates Cysteine-rich Protein 2 in Vascular Smooth Muscle Cells via Activating Transcription Factor 2*

M. Layne, S. yet, A. Tseng, 2008, Journal of Biological Chemistry.

Increased Neointima Formation in Cysteine-Rich Protein 2–Deficient Mice in Response to Vascular Injury

D. Simon, M. Layne, S. yet, 2005, Circulation research.

Elk-3 Is a Transcriptional Repressor of Nitric-oxide Synthase 2*

M. Layne, S. yet, Yen-Hsu Chen, 2003, Journal of Biological Chemistry.

Human EZF, a Krüppel-like Zinc Finger Protein, Is Expressed in Vascular Endothelial Cells and Contains Transcriptional Activation and Repression Domains*

Hong Wang, S. Folta, C. Hsieh, 1998, The Journal of Biological Chemistry.

Regulation of smooth muscle cell differentiation by AT-rich interaction domain transcription factors Mrf2alpha and Mrf2beta.

Masafumi Watanabe, C. Hsieh, K. Maemura, 2002, Circulation research.

Regulation of Smooth Muscle Cell Differentiation by AT-Rich Interaction Domain Transcription Factors Mrf2 (cid:1) and Mrf2 (cid:2)

Masafumi Watanabe, C. Hsieh, K. Maemura, 2002 .

Regulation of Myogenic Terminal Differentiation by the Hairy-related Transcription Factor CHF2*

J. Liao, M. Chin, M. Layne, 2001, The Journal of Biological Chemistry.

Absence of adipocyte fatty acid binding protein prevents the development of accelerated atherosclerosis in hypercholesterolemic mice

B. Schreiber, Dezheng Zhao, C. Hsieh, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Divergent signaling pathways cooperatively regulate TGFβ induction of cysteine-rich protein 2 in vascular smooth muscle cells

Linyi Chen, M. Layne, S. yet, 2014, Cell Communication and Signaling.

The glycosylation-dependent interaction of perlecan core protein with LDL: implications for atherosclerosis

S. Shaw, K. Ravid, P. Robbins, 2015, Journal of Lipid Research.

Modulation of cysteine-rich protein 2 expression in vascular injury and atherosclerosis

M. Layne, S. yet, Meng-Ling Wu, 2014, Molecular Biology Reports.

Cysteine-rich protein 2 alters p130Cas localization and inhibits vascular smooth muscle cell migration.

K. Kirsch, Y. Chuang, M. Layne, 2013, Cardiovascular research.

In Vitro System for Differentiating Pluripotent Neural Crest Cells into Smooth Muscle Cells*

D. Stemple, N. Sibinga, C. Hsieh, 1998, The Journal of Biological Chemistry.

Genomic Cloning and Promoter Analysis of Aortic Preferentially Expressed Gene-1

C. Hsieh, M. Layne, S. yet, 1999, The Journal of Biological Chemistry.

a Novel Cycle-like Factor , Regulates the Circadian Oscillation of Plasminogen Activator Inhibitor-1 Gene Expression *

C. Hsieh, M. Chin, K. Maemura, 2000 .

Discoidin Domain Receptor 2 Impairs Insulin-stimulated Insulin Receptor Substrate-1 Tyrosine Phosphorylation and Glucose Uptake in 3T3-L1 Adipocytes

A. Sorisky, M. Layne, A. Gagnon, 2007, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Adrenergic Reprogramming of Preexisting Adipogenic Trajectories Steer Naïve Mural Cells Toward Beige Differentiation

S. Farmer, M. Layne, Jean Z. Lin, 2023, bioRxiv.

DOWNREGULATION OF KLF4 BY MIR-143/145 IS CRITICAL FOR MODULATION OF VASCULAR SMOOTH MUSCLE CELL PHENOTYPE BY TGF- β AND BMP

B. Davis-Dusenbery, A. Hata, Alexandra S. Weisman, 2011 .

Gene Therapy Strategy for Long-Term Myocardial Protection Using Adeno-Associated Virus-Mediated Delivery of Heme Oxygenase Gene

J. Oyama, A. Mangi, M. Layne, 2002, Circulation.

The Production, Efficacy, and Safety of Machine-Generated Bicarbonate Solution for Continuous Venovenous Hemodialysis (CVVHD): The Cleveland Clinic Method

J. Sedor, M. Layne, Gladys Thomas, 2021, Kidney medicine.

Aortic carboxypeptidase-like protein is expressed in fibrotic human lung and its absence protects against bleomycin-induced lung fibrosis.

M. Layne, S. Schissel, M. Perrella, 2009, American Journal of Pathology.