C. Dugovic

发表

Current understanding of the circadian clock and the clinical implications for neurological disorders.

P. Zee, F. Turek, C. Dugovic, 2001, Archives of neurology.

PHYSIOLOGY OF SLEEP (REVIEW)–Interactions between stress and sleep: from basic research to clinical situations

Rachel Leproult, K. Spiegel, R. Leproult, 2000 .

Pre-clinical characterization of aryloxypyridine amides as histamine H3 receptor antagonists: identification of candidates for clinical development.

P. Bonaventure, Kiev S. Ly, T. Lovenberg, 2010, Bioorganic & medicinal chemistry letters.

Histamine H3 receptor antagonists: from target identification to drug leads.

P. Bonaventure, F. Kamme, T. Lovenberg, 2007, Biochemical pharmacology.

Acute wake‐promoting actions of JNJ‐5207852, a novel, diamine‐based H3 antagonist

Sandy J. Wilson, T. Lovenberg, N. Carruthers, 2004 .

Direct Imaging of Hippocampal Epileptiform Calcium Motifs Following Kainic Acid Administration in Freely Behaving Mice

Mark J. Schnitzer, E. Paxon Frady, Jonathan J. Nassi, 2016, Front. Neurosci..

F. Turek, C. Dugovic, F W Turek, 2001, Neuroreport.

Sleep in the Wistar‐Kyoto rat, a putative genetic animal model for depression

L. Solberg, F. Turek, C. Dugovic, 2000, Neuroreport.

β1 and β2 adrenergic receptors: Their role in the regulation of paradoxical sleep in the rat

L. Lanfumey, C. Dugovic, J. Adrien, 1985 .

Corrigendum to acute wake‐promoting actions of JNJ‐5207852, a novel, diamine‐based H3 antagonist

T. Lovenberg, X. Langlois, C. Berridge, 2005, British journal of pharmacology.

Survey on the pharmacodynamics of the new antipsychotic risperidone

J. Leysen, A. Megens, T. Meert, 1994, Psychopharmacology.

Novel Octahydropyrrolo[3,4-c]pyrroles Are Selective Orexin-2 Antagonists: SAR Leading to a Clinical Candidate.

P. Bonaventure, Kiev S. Ly, T. Lovenberg, 2015, Journal of medicinal chemistry.

Characterization of JNJ-42847922, a Selective Orexin-2 Receptor Antagonist, as a Clinical Candidate for the Treatment of Insomnia

P. Bonaventure, T. Lovenberg, N. Carruthers, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Putative role of GPR139 on sleep modulation using pharmacological and genetic rodent models.

P. Bonaventure, C. Dvorak, T. Lovenberg, 2020, European journal of pharmacology.

Chapter 26 – Master Circadian Clock, Master Circadian Rhythm

F. Turek, C. Dugovic, A. Laposky, 2005 .

Translational evaluation of novel selective orexin-1 receptor antagonist JNJ-61393215 in an experimental model for panic in rodents and humans

T. P. Lebold, P. Bonaventure, W. Drevets, 2020, Translational Psychiatry.

Substituted Azabicyclo[2.2.1]heptanes as Selective Orexin-1 Antagonists: Discovery of JNJ-54717793.

P. Bonaventure, C. Dvorak, T. Lovenberg, 2020, ACS medicinal chemistry letters.

Orexin-1 receptor blockade dysregulates REM sleep in the presence of orexin-2 receptor antagonism

P. Bonaventure, T. Lovenberg, C. Dugovic, 2014, Front. Neurosci..

Translational evaluation of JNJ-18038683, a 5-HT7 receptor antagonist, on REM sleep and in major depressive disorder

P. Bonaventure, C. Dvorak, T. Lovenberg, 2012 .

REM sleep and in major depressive disorder

P. Bonaventure, W. Chai, C. Dvorak, 2012 .

JNJ-39220675, a novel selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats

E. Levin, P. Bonaventure, T. Lovenberg, 2011, Psychopharmacology.

Effects of lithium on dopamine behavioural supersensitivity induced by rapid eye movement sleep deprivation.

C. Dugovic, A. Wauquier, F. Arriaga, 1988, Neuropsychobiology.

Pharmacological characterization of JNJ-28583867, a histamine H(3) receptor antagonist and serotonin reuptake inhibitor.

P. Bonaventure, Sandy J. Wilson, T. Lovenberg, 2007, European journal of pharmacology.

Zolpidem Reduces Hippocampal Neuronal Activity in Freely Behaving Mice: A Large Scale Calcium Imaging Study with Miniaturized Fluorescence Microscope

Mark J. Schnitzer, Yaniv Ziv, Sujin Yun, 2014, PloS one.

Diamine-based human histamine H3 receptor antagonists: (4-aminobutyn-1-yl)benzylamines.

P. Bonaventure, J. A. Jablonowski, C. Dvorak, 2009, European journal of medicinal chemistry.

Pharmacologic Characterization of JNJ-42226314, [1-(4-Fluorophenyl)indol-5-yl]-[3-[4-(thiazole-2-carbonyl)piperazin-1-yl]azetidin-1-yl]methanone, a Reversible, Selective, and Potent Monoacylglycerol Lipase Inhibitor

P. Bonaventure, T. Lovenberg, P. Connolly, 2019, The Journal of Pharmacology and Experimental Therapeutics.

Serotonin and Sleep‐Wakefulness

C. Dugovic, A. Wauquier, Albert Wauquier, 1990, Annals of the New York Academy of Sciences.

Changing Views on the Role of Serotonergic Mechanisms in the Control of the Sleep-Wakefulness Cycle

C. Dugovic, A. Wauquier, P. Janssen, 1990 .

Presence of a paradoxical sleep (PS) factor in the cerebrospinal fluid of PS-deprived rats.

C. Dugovic, J. Adrien, 1984, European journal of pharmacology.

High Corticosterone Levels in Prenatally Stressed Rats Predict Persistent Paradoxical Sleep Alterations

F. Turek, S. Maccari, C. Dugovic, 1999, The Journal of Neuroscience.

Sleep-wakefulness patterns in the helpless rat

C. Dugovic, Patrick Martin, J. Adrien, 1991, Physiology & Behavior.

Functional activity of 5‐HT2 receptors in the modulation of the sleep/wakefulness states

C. Dugovic, 1992, Journal of sleep research.

Slow Wave Sleep: Physiological, Pathophysiological and Functional Aspects

M. Radulovački, C. Dugovic, A. Wauquier, 1989 .

5-HT2 receptors could be primarily involved in the regulation of slow-wave sleep in the rat.

C. Dugovic, A. Wauquier, 1987, European journal of pharmacology.

A Selective Orexin-1 Receptor Antagonist Attenuates Stress-Induced Hyperarousal without Hypnotic Effects

T. P. Lebold, P. Bonaventure, T. Lovenberg, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Melatonin modulates the sensitivity of 5-hydroxytryptamine-2 receptor-mediated sleep—wakefulness regulation in the rat

J. Leysen, C. Dugovic, A. Wauquier, 1989, Neuroscience Letters.

Behavioral characterization of mice lacking histamine H(3) receptors.

T. Lovenberg, W. Fung-Leung, K. Ngo, 2002, Molecular pharmacology.

The selective neurokinin 1 receptor antagonist R116301 modulates photic responses of the hamster circadian system

F. Turek, C. Dugovic, O. Reeth, 2001, Neuropharmacology.

Altered sleep regulation in leptin-deficient mice.

F. Turek, J. Bass, C. Dugovic, 2006, American journal of physiology. Regulatory, integrative and comparative physiology.

Deletion of the mammalian circadian clock gene BMAL1/Mop3 alters baseline sleep architecture and the response to sleep deprivation.

F. Turek, C. Dugovic, C. Bradfield, 2005, Sleep.

Role of serotonin in sleep mechanisms.

C. Dugovic, 2001, Revue neurologique.

Blockade of Orexin-1 Receptors Attenuates Orexin-2 Receptor Antagonism-Induced Sleep Promotion in the Rat

P. Bonaventure, C. Dvorak, T. Lovenberg, 2009, Journal of Pharmacology and Experimental Therapeutics.

5-HT7 receptor deletion enhances REM sleep suppression induced by selective serotonin reuptake inhibitors, but not by direct stimulation of 5-HT1A receptor

P. Bonaventure, T. Lovenberg, C. Dugovic, 2009, Neuropharmacology.

Metabolic Syndrome Altered sleep regulation in leptin-deficient mice

F. Turek, J. Bass, C. Dugovic, 2005 .

Selective Blockade of 5-Hydroxytryptamine (5-HT)7 Receptors Enhances 5-HT Transmission, Antidepressant-Like Behavior, and Rapid Eye Movement Sleep Suppression Induced by Citalopram in Rodents

P. Bonaventure, T. Lovenberg, J. Atack, 2007, Journal of Pharmacology and Experimental Therapeutics.

Differential effects of the new antipsychotic risperidone on sleep and wakefulness in the rat

C. Dugovic, A. Wauquier, P. Janssen, 1989, Neuropharmacology.

Effects of ritanserin and chlordiazepoxide on sleep-wakefulness alterations in rats following chronic cocaine treatment

T. Meert, C. Dugovic, G. Clincke, 2005, Psychopharmacology.

Pharmacological Modulation of the Serotonergic System: an Overview of the Effects on Normal and Pathological Sleep

C. Dugovic, G. Clincke, 1993 .

Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8

T. Lovenberg, N. Carruthers, T. Steckler, 2016, The Journal of Pharmacology and Experimental Therapeutics.

The light-dark cycle modulates the effects of ritanserin on sleep-wakefulness patterns in the rat

J. Leysen, C. Dugovic, A. Wauquier, 1989, Pharmacology Biochemistry and Behavior.

RBD--an emerging clue to neurodegenerative disorders.

F. Turek, C. Dugovic, 2005, Sleep.

Diurnal sex differences in the sleep-wake cycle of mice are dependent on gonadal function.

F. Turek, C. Dugovic, K. Paul, 2006, Sleep.

Functional role of 5-HT2 receptors in the regulation of sleep and wakefulness in the rat

J. Leysen, P. Janssen, C. Dugovic, 2004, Psychopharmacology.

Evaluation of JNJ-54717793 a Novel Brain Penetrant Selective Orexin 1 Receptor Antagonist in Two Rat Models of Panic Attack Provocation

P. Bonaventure, T. Lovenberg, A. Shekhar, 2017, Front. Pharmacol..

Selective Inhibition of Orexin-2 Receptors Prevents Stress-Induced ACTH Release in Mice

P. Bonaventure, T. Lovenberg, C. Dugovic, 2017, Frontiers in Behavioral Neuroscience.

Neurochemical profile of orexin receptor antagonists : awakening the neurochemistry of sleep

P. Bonaventure, C. Dvorak, T. Lovenberg, 2008 .

Pharmacological or genetic orexin1 receptor inhibition attenuates MK-801 induced glutamate release in mouse cortex

P. Bonaventure, T. Lovenberg, Tamara Berdyyeva, 2014, Front. Neurosci..

Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-g 8 s

T. Lovenberg, N. Carruthers, T. Steckler, 2016 .

Time course of night sleep EEG in the first year of life: a description based on automatic analysis.

H. Schulz, F. Bes, C. Dugovic, 1988, Electroencephalography and clinical neurophysiology.

Selective pharmacological blockade of the 5-HT7 receptor attenuates light and 8-OH-DPAT induced phase shifts of mouse circadian wheel running activity

P. Bonaventure, C. Dvorak, T. Lovenberg, 2015, Front. Behav. Neurosci..

Novel benzamide-based histamine h3 receptor antagonists: the identification of two candidates for clinical development.

P. Bonaventure, Kiev S. Ly, T. Lovenberg, 2015, ACS Medicinal Chemistry Letters.

Translational Evaluation of JNJ-18038683, a 5-Hydroxytryptamine Type 7 Receptor Antagonist, on Rapid Eye Movement Sleep and in Major Depressive Disorder

P. Bonaventure, C. Dvorak, T. Lovenberg, 2012, Journal of Pharmacology and Experimental Therapeutics.