Kevin R Coombes

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Decomposing the Apoptosis Pathway Into Biologically Interpretable Principal Components

Min Wang, Steven M Kornblau, Kevin R Coombes, 2018, Cancer informatics.

Inter-Gene Correlation on Oligonucleotide Arrays

Kevin R Coombes, David L Gold, Jing Wang, 2005, American journal of pharmacogenomics : genomics-related research in drug development and clinical practice.

Statistical contributions to proteomic research.

Jeffrey S. Morris, Kevin R Coombes, Jeffrey S Morris, 2010, Methods in molecular biology.

TAD: a web interface and database for tissue microarrays.

Kevin R Coombes, Lin Zhang, Carlos Bueso-Ramos, 2002, Applied bioinformatics.

Inferring clonal heterogeneity in cancer using SNP arrays and whole genome sequencing

Kevin R Coombes, Zachary B. Abrams, Mark R Zucker, 2019, Bioinform..

BAYESIAN SPARSE GRAPHICAL MODELS FOR CLASSIFICATION WITH APPLICATION TO PROTEIN EXPRESSION DATA.

Yuan Ji, Yiling Lu, Veerabhadran Baladandayuthapani, 2014, The annals of applied statistics.

Response to Preprocessing of oligonucleotide array data

Chunlei Wu, Kevin R Coombes, Li Zhang, 2004, Nature Biotechnology.

Bayesian Analysis of Mass Spectrometry Proteomic Data Using Wavelet‐Based Functional Mixed Models

Jeffrey S. Morris, Kevin R Coombes, Jeffrey S Morris, 2008, Biometrics.

Unsupervised machine learning and prognostic factors of survival in chronic lymphocytic leukemia

Kevin R Coombes, Zachary B. Abrams, Caitlin E. Coombes, 2020, J. Am. Medical Informatics Assoc..

Inferring clonal heterogeneity in cancer using SNP arrays and whole genome sequencing

Kevin R Coombes, Mark R Zucker, Lynne V Abruzzo, 2019, Bioinform..

Relax with CouchDB--into the non-relational DBMS era of bioinformatics.

Kevin R Coombes, Ganiraju Manyam, Lynne V Abruzzo, 2012, Genomics.

Run batch effects potentially compromise the usefulness of genomic signatures for ovarian cancer.

Kevin R Coombes, Keith A Baggerly, K. Coombes, 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Individualized molecular medicine: linking functional proteomics to select therapeutics targeting the PI3K pathway for specific patients.

Yiling Lu, Gordon B Mills, Kevin R Coombes, 2008, Advances in experimental medicine and biology.

Serum proteomics profiling—a young technology begins to mature

Jeffrey S. Morris, Kevin R Coombes, Jianhua Hu, 2005, Nature Biotechnology.

Functional Proteomic Analysis of Advanced Serous Ovarian Cancer Using Reverse Phase Protein Array: TGF-β Pathway Signaling Indicates Response to Primary Chemotherapy

Fan Zhang, Yiling Lu, Gordon B Mills, 2010, Clinical Cancer Research.

Sources of nonlinearity in cDNA microarray expression measurements

Kevin R Coombes, Wei Zhang, Latha Ramdas, 2001, Genome Biology.

Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1.

Michael Peyton, Li Shen, John N Weinstein, 2012, Cancer discovery.

The BATTLE-2 Study: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small-Cell Lung Cancer.

Li Shen, John V Heymach, Kevin R Coombes, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Role of peroxisome proliferator-activated receptor-gamma and its coactivator DRIP205 in cellular responses to CDDO (RTA-401) in acute myelogenous leukemia.

Kevin R Coombes, Zhenlin Ju, Marina Konopleva, 2010, Cancer research.

Serum amyloid A as a tumor marker in sera of nude mice with orthotopic human pancreatic cancer and in plasma of patients with pancreatic cancer.

Kevin R Coombes, John Koomen, David Hawke, 2005, International journal of oncology.

Plasma protein profiling for diagnosis of pancreatic cancer reveals the presence of host response proteins.

Kevin R Coombes, John M Koomen, K. Coombes, 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.

Ovarian cancer: linking genomics to new target discovery and molecular markers--the way ahead.

Yiling Lu, Gordon B Mills, Kevin R Coombes, 2008, Advances in experimental medicine and biology.

High expression of activation-induced cytidine deaminase (AID) and splice variants is a distinctive feature of poor-prognosis chronic lymphocytic leukemia.

Kevin R Coombes, Jing Wang, Lynne V Abruzzo, 2003, Blood.

Stem cell-ness: a "magic marker" for cancer.

Gordon B Mills, Kevin R Coombes, K. Coombes, 2005, The Journal of clinical investigation.

Use of reverse phase protein microarrays to study protein expression in leukemia: technical and methodological lessons learned.

Steven M Kornblau, Kevin R Coombes, K. Coombes, 2011, Methods in molecular biology.

Association between ductal fluid proteomic expression profiles and the presence of lymph node metastases in women with breast cancer.

Kevin R Coombes, Savitri Krishnamurthy, Henry M Kuerer, 2004, Surgery.

Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome.

John V Heymach, Kevin R Coombes, Lixia Diao, 2012, Journal of the National Cancer Institute.

Functional proteomic profiling of AML predicts response and survival.

Gordon B Mills, Steven M Kornblau, Kevin R Coombes, 2009, Blood.

Biological validation of differentially expressed genes in chronic lymphocytic leukemia identified by applying multiple statistical methods to oligonucleotide microarrays.

Kevin R Coombes, Jing Wang, Lynne V Abruzzo, 2005, The Journal of molecular diagnostics : JMD.

microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival.

George A Calin, Kevin R Coombes, Muller Fabbri, 2010, Blood.

Bayesian Shrinkage Estimation of the Relative Abundance of mRNA Transcripts Using SAGE

Jeffrey S. Morris, Kevin R Coombes, Jeffrey S Morris, 2003, Biometrics.

Abnormal expression of FLI1 protein is an adverse prognostic factor in acute myeloid leukemia.

Steven M Kornblau, Kevin R Coombes, K. Coombes, 2011, Blood.

Validation of oligonucleotide microarray data using microfluidic low-density arrays: a new statistical method to normalize real-time RT-PCR data.

Kevin R Coombes, Lynne V Abruzzo, Michael J Keating, 2005, BioTechniques.

Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities.

Michael Peyton, Humam Kadara, Murim Choi, 2015, Cancer discovery.

Gene expression profile of metastatic human pancreatic cancer cells depends on the organ microenvironment.

Kevin R Coombes, K. Coombes, I. Fidler, 2007, Cancer research.

Melanoma antigen family A identified by the bimodality index defines a subset of triple negative breast cancers as candidates for immune response augmentation.

Kevin R Coombes, Lajos Pusztai, Eugen Ruckhäberle, 2012, European journal of cancer.