G. Shore

P. Branton, J. G. Teodoro, G. Shore, 1996, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

p28 Bap31, a Bcl-2/Bcl-XL- and Procaspase-8–associated Protein in the Endoplasmic Reticulum

P. Branton, T. Kwan, J. A. Cromlish, 1997, The Journal of cell biology.

Antagonism of Beclin 1‐dependent autophagy by BCL‐2 at the endoplasmic reticulum requires NAF‐1

G. Shore, M. Germain, M. Nguyen, 2010, The EMBO journal.

Bcl-2 and calcium: controversy beneath the surface

G. Shore, C. Distelhorst, Gordon C Shore, 2004, Oncogene.

The Small Molecule GMX1778 Is a Potent Inhibitor of NAD+ Biosynthesis: Strategy for Enhanced Therapy in Nicotinic Acid Phosphoribosyltransferase 1-Deficient Tumors

Karine Gilbert, Denis Paquette, Richard Marcellus, 2009, Molecular and Cellular Biology.

Endoplasmic reticulum BIK initiates DRP1‐regulated remodelling of mitochondrial cristae during apoptosis

H. McBride, G. Shore, M. Germain, 2005, The EMBO journal.

Bcl-xL regulates metabolic efficiency of neurons through interaction with the mitochondrial F1FO ATP synthase

Shanta M. Messerli, L. Bonanni, G. Shore, 2011, Nature Cell Biology.

Programming cancer cells for high expression levels of Mcl1

A. Roulston, G. Shore, M. Nguyen, 2013, EMBO reports.

Mitochondrion-dependent N-terminal Processing of Outer Membrane Mcl-1 Protein Removes an Essential Mule/Lasu1 Protein-binding Site*

Jason C. Young, M. Warr, M. O’Connor-McCourt, 2011, The Journal of Biological Chemistry.

Small molecule obatoclax (GX15-070) antagonizes MCL-1 and overcomes MCL-1-mediated resistance to apoptosis

Laurent Bélec, Ricky W. Johnstone, E. Purisima, 2007, Proceedings of the National Academy of Sciences.

The interaction of a synthetic mitochondrial signal peptide with lipid membranes is independent of transbilayer potential.

G. Shore, J. Silvius, I. Skerjanc, 1987, The EMBO journal.

A synthetic signal peptide blocks import of precursor proteins destined for the mitochondrial inner membrane or matrix.

R. Hodges, K. Freeman, A. Taneja, 1985, The Journal of biological chemistry.

The Yeast Split-Ubiquitin Membrane Protein Two-Hybrid Screen Identifies BAP31 as a Regulator of the Turnover of Endoplasmic Reticulum-Associated Protein Tyrosine Phosphatase-Like B

J. Pelletier, M. Massaad, A. Herscovics, 2004, Molecular and Cellular Biology.

Granzyme B–Mediated Cytochrome C Release Is Regulated by the Bcl-2 Family Members Bid and Bax

D. Green, M. Pinkoski, I. Goping, 2000, The Journal of experimental medicine.

BID-dependent and BID-independent pathways for BAX insertion into mitochondria

S. Korsmeyer, A. Gross, I. Goping, 2000, Cell Death and Differentiation.

E1A-induced Processing of Procaspase-8 Can Occur Independently of FADD and Is Inhibited by Bcl-2*

E. Alnemri, T. Mak, P. Branton, 1998, The Journal of Biological Chemistry.

Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol

G. Shore, R. Marcellus, D. Breckenridge, 2003, The Journal of cell biology.

Uncleaved BAP31 in Association with A4 Protein at the Endoplasmic Reticulum Is an Inhibitor of Fas-initiated Release of Cytochromec from Mitochondria*

P. Clemons, G. Shore, Bing Wang, 2003, The Journal of Biological Chemistry.

Targeting of Bcl-2 to the mitochondrial outer membrane by a COOH-terminal signal anchor sequence.

S. Korsmeyer, S. Korsmeyer, G. Shore, 1993, The Journal of biological chemistry.

A method for efficient and selective recovery of membrane glycoproteins from concanavalin A-Sepharose using media containing sodium dodecyl sulfate and urea.

G. Shore, L. Poliquin, 1980, Analytical biochemistry.

BIM, PUMA, and the Achilles’ Heel of Oncogene Addiction

A. Roulston, W. Muller, G. Shore, 2013, Science Signaling.

Mitochondrial membrane dynamics, cristae remodelling and apoptosis.

G. Shore, H. Heath-Engel, 2006, Biochimica et biophysica acta.

The carbamyl phosphate synthetase promoter contains multiple binding sites for C/EBP-related proteins.

I. Goping, G. Shore, C. Mueller, 1992, Gene.

Translation initiation factor eIF4F modifies the dexamethasone response in multiple myeloma

J. Pelletier, Christof Fellmann, A. Roulston, 2014, Proceedings of the National Academy of Sciences.

E4orf4, a Novel Adenovirus Death Factor That Induces p53-independent Apoptosis by a Pathway That Is Not Inhibited by zVAD-fmk

P. Branton, G. Shore, R. Marcellus, 1998, The Journal of cell biology.

a Novel Adenovirus Death Factor That Induces p 53-independent Apoptosis by a Pathway That Is Not Inhibited by zVAD-fmk

P. Branton, G. Shore, R. Marcellus, 1998 .

Cadmium exposure induces mitochondria-dependent apoptosis in oligodendrocytes.

G. Almazan, G. Shore, M. Nguyen, 2009, Neurotoxicology.

The X-ray structure of a BAK homodimer reveals an inhibitory zinc binding site.

A. Tocilj, K. Gehring, G. Shore, 2006, Molecular cell.

Regulated targeting of Bax and Bak to intracellular membranes during apoptosis

G. Shore, H. Heath-Engel, 2006, Cell Death and Differentiation.

Induction and endoplasmic reticulum location of BIK/NBK in response to apoptotic signaling by E1A and p53

G. Shore, M. Germain, Gordon C Shore, 2002, Oncogene.

The procaspase-8 isoform, procaspase-8L, recruited to the BAP31 complex at the endoplasmic reticulum

M. Nguyen, M. Reth, G. Shore, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Bcl-2 and adenovirus E1B 19 kDA protein prevent E1A-induced processing of CPP32 and cleavage of poly(ADP-ribose) polymerase.

P. Branton, G. Poirier, J. G. Teodoro, 1996, Oncogene.

Role of membrane anchor domain of Bcl-2 in suppression of apoptosis caused by E1B-defective adenovirus.

Z. Oltvai, S. Korsmeyer, P. Branton, 1994, The Journal of biological chemistry.

A signal-anchor sequence selective for the mitochondrial outer membrane

H. McBride, G. Shore, J. Li, 1992, The Journal of cell biology.

Reversal of the orientation of an integral protein of the mitochondrial outer membrane.

G. Shore, J. Li, 1992, Science.

BCL-2 phosphorylation modulates sensitivity to the BH3 mimetic GX15-070 (Obatoclax) and reduces its synergistic interaction with bortezomib in chronic lymphocytic leukemia cells

E. Campo, E. Montserrat, N. Villamor, 2008, Leukemia.

Solution Structure of Human BCL-w

K. Gehring, P. Beauparlant, G. Shore, 2003, Journal of Biological Chemistry.

Small-molecule Bcl-2 antagonists as targeted therapy in oncology

M. Warr, G. Shore, 2008, Current oncology.

Bcl2 at the endoplasmic reticulum protects against a Bax/Bak-independent paraptosis-like cell death pathway initiated via p20Bap31.

B. Wang, G. Shore, H. Heath-Engel, 2012, Biochimica et biophysica acta.

Protein sorting between mitochondrial outer and inner membranes. Insertion of an outer membrane protein into the inner membrane.

G. Shore, J. Li, 1992, Biochimica et biophysica acta.

In vitro synthesis and assembly of a 68 kDa outer mitochondrial membrane protein from rat liver.

R. Rachubinski, G. Shore, C. Noël, 1985, Biochimica et biophysica acta.

Biogenesis of a 35-kilodalton protein associated with outer mitochondrial membrane in rat liver.

G. Shore, M. Bendayan, P. Carignan, 1981, Journal of Biological Chemistry.

Particulate glucan synthetase activity: generation and inactivation after treatments with indoleacetic acid and cycloheximide.

F. S. Spencer, G. Shore, B. Ziola, 1972, Archives of biochemistry and biophysics.

Fate of polypeptides synthesized on rough microsomal vesicles in a messenger-dependent rabbit reticulocyte system

G. Shore, R. Harris, 1977, The Journal of cell biology.

The precursor to ornithine carbamyl transferase is transported to mitochondria as a 5S complex containing an import factor.

G. Shore, C. Argan, 1985, Biochemical and biophysical research communications.

Processing of the precursor for the mitochondrial enzyme, carbamyl phosphate synthetase. Inhibition by rho-aminobenzamidine leads to very rapid degradation (clearing) of the precursor.

G. Shore, Y. Raymond, 1981, The Journal of biological chemistry.

Uniform nomenclature for the protein transport machinery of the mitochondrial membranes.

W. Neupert, N. Pfanner, G. Shore, 1996, Trends in biochemical sciences.

Synergy between the NAMPT inhibitor GMX1777(8) and pemetrexed in non-small cell lung cancer cells is mediated by PARP activation and enhanced NAD consumption.

A. Roulston, Gäelle Bridon, D. Avizonis, 2014, Cancer research.

Regulation of apoptosis by E1A and Myc oncoproteins.

G. Shore, D. Breckenridge, 2000, Critical reviews in eukaryotic gene expression.

BAP31 Interacts with Sec61 Translocons and Promotes Retrotranslocation of CFTRΔF508 via the Derlin-1 Complex

B. Wang, David Y. Thomas, Donglei Zhang, 2008, Cell.

Dissociating the dual roles of apoptosis‐inducing factor in maintaining mitochondrial structure and apoptosis

David S. Park, H. McBride, J. Penninger, 2006, The EMBO journal.

Identification of the human mitochondrial protein import receptor, huMas20p. Complementation of Δmas20 in yeast

G. Shore, D. Millar, Ing Swie Goping, 1995, FEBS letters.

Rat carbamyl-phosphate synthetase I gene. Promoter sequence and tissue-specific transcriptional regulation in vitro.

C. J. Lusty, G. Shore, B. Howell, 1987, Journal of Biological Chemistry.

Indoleacetic acid stimulates cellulose deposition and selectively enhances certain beta-glucan synthetase activities.

G. Shore, G. Maclachlan, 1973, Biochimica et Biophysica Acta.

The Site of Cellulose Synthesis: Cell Surface and Intracellular beta-1, 4-Glucan (Cellulose) Synthetase Activities in Relation to the Stage and Direction of Cell Growth.

G. Shore, Y. Raymond, G. Maclachlan, 1975, Plant physiology.

CELL SURFACE AND INTRACELLULAR f-1,4-GLUCAN (CELLULOSE) SYNTHETASE ACTIVITIES IN RELATION TO THE STAGE AND DIRECTION OF CELL GROWTH'

G. Shore, Y. Raymond, G. Maclachlan, 1975 .

Import and insertion of proteins into the mitochondrial outer membrane.

H. McBride, G. Shore, N. Steenaart, 1995, European journal of biochemistry.

Targeting and Insertion of Proteins into the Mitochondrial Outer Membrane

H. McBride, G. Shore, N. Steenaart, 1996 .

Determinants of Outer Membrane Protein Sorting and Topology in Mitochondria

H. McBride, Jian-ming Li, G. Shore, 1993 .

Cloning and Characterization of a 35-kDa Mouse Mitochondrial Outer Membrane Protein MOM35 with High Homology to Tom40

E. Schleiff, G. Shore, Irene Lee Rivera, 2000, Journal of bioenergetics and biomembranes.

BH3‐ligand regulates access of MCL‐1 to its E3 ligase

M. Blanchette, M. Warr, S. Wing, 2005, FEBS letters.

Fis1, Bap31 and the kiss of death between mitochondria and endoplasmic reticulum

G. Shore, Bing Wang, M. Nguyen, 2011, The EMBO journal.

A signal sequence domain essential for processing, but not import, of mitochondrial pre-ornithine carbamyl transferase

G. Shore, W. Sheffield, A. W. Bell, 1987, The Journal of cell biology.

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Sara W. Bird, Erinna F. Lee, Michael D. Kim, 2016 .

Calnexin deficiency and endoplasmic reticulum stress-induced apoptosis.

M. Michalak, M. Opas, G. Shore, 2002, Biochemistry.

Mitochondrial ATP synthase displays features that are characteristic of themPTP. Itsactivityis inhibited by theconcurrentbindingof thetwo

G. Shore, E. McNay, Emma Lazrove, 2015 .

Modulating the bcl-2 family of apoptosis suppressors for potential therapeutic benefit in cancer.

G. Shore, J. Viallet, Gordon C Shore, 2005, Hematology. American Society of Hematology. Education Program.

Structural analysis and amphiphilic properties of a chemically synthesized mitochondrial signal peptide.

S W Hui, R. Epand, G. Shore, 1986, The Journal of biological chemistry.

Protein Insertion Into The Outer Mitochondrial Membrane

G. Shore, D. Millar, 1993 .

Identification of hydrophobic residues in the signal sequence of mitochondrial preornithine carbamyltransferase that enhance the rate of precursor import.

G. Shore, J. Silvius, I. Skerjanc, 1988, Journal of Biological Chemistry.

Interactions between repressor and anti-repressor elements in the carbamyl phosphate synthetase I promoter.

I. Goping, G. Shore, 1994, The Journal of biological chemistry.

Human mitochondrial import receptor, Tom20p. Use of glutathione to reveal specific interactions between Tom20‐glutathione S‐transferase and mitochondrial precursor proteins

E. Schleiff, I. Goping, G. Shore, 1997, FEBS letters.

Chloramphenicol inhibits hormone-dependent induction of cytoplasmic mRNA coding for the mitochondrial enzyme, carbamyl phosphate synthetase, in Rana catesbeiana tadpoles.

G. Shore, M. Pouchelet, 1981, Biochimica et biophysica acta.

The resident endoplasmic reticulum protein, BAP31, associates with gamma-actin and myosin B heavy chain.

G. Shore, A. Ducret, D. Breckenridge, 2003, European journal of biochemistry.

Induction of p53-independent apoptosis by hygromycin B: suppression by Bcl-2 and adenovirus E1B 19-kDa protein.

P. Branton, G. Shore, G. Chen, 1995, Experimental Cell Research.

PARP activation and enhanced NAD consumption pemetrexed in non-small cell lung cancer cells is mediated by Synergy between the NAMPT inhibitor GMX 1777 ( 8 ) and

A. Roulston, Gäelle Bridon, D. Avizonis, 2014 .

Import of hybrid vesicular stomatitis G protein to the mitochondrial inner membrane.

G. Shore, M. Nguyen, 1987, The Journal of biological chemistry.

Two fractions of rough endoplasmic reticulum from rat liver. II. Cytoplasmic messenger RNA's which code for albumin and mitochondrial proteins are distributed differently between the two fractions

G. Shore, J. Tata, 1977, The Journal of cell biology.

Therapeutic activation of caspases in cancer: a question of selectivity.

P. Beauparlant, G. Shore, 2003, Current opinion in drug discovery & development.

Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol

G. Shore, R. Marcellus, D. Breckenridge, 2003, The Journal of cell biology.

Chapter 16 Gel retardation assays and DNA footprinting

I. Goping, G. Shore, D. Underhill, 1995 .

An amphiphilic lipid-binding domain influences the topology of a signal-anchor sequence in the mitochondrial outer membrane.

G. Shore, J. Silvius, N. Steenaart, 1996, Biochemistry.