B. Pitt

发表

Nitric oxide-induced modification of protein thiolate clusters as determined by spectral fluorescence resonance energy transfer in live endothelial cells.

Simon C Watkins, Claudette M St Croix, Bruce R Pitt, 2004, Free radical biology & medicine.

IL-33-mediated IL-13 secretion by ST2+ Tregs controls inflammation after lung injury.

K. M. Robinson, J. Alcorn, U. Chandran, 2019, JCI insight.

Targeted gene delivery to pulmonary endothelium by anti-PECAM antibody.

Y. Tan, B. Pitt, L. Huang, 2000, American journal of physiology. Lung cellular and molecular physiology.

Expression of iNOS in cultured rat pulmonary artery smooth muscle cells is inhibited by the heat shock response.

H. Wong, K. Wasserloos, B. Pitt, 1995, The American journal of physiology.

Pulmonary alveolar epithelial inducible NO synthase gene expression: regulation by inflammatory mediators.

Simon C Watkins, C. Lowenstein, B. Freeman, 1995, The American journal of physiology.

Efficient intracellular delivery of oligonucleotides formulated in folate receptor-targeted lipid vesicles.

B. Pitt, Song Li, Annette Wilson, 2002, Bioconjugate chemistry.

Protein-tyrosine Phosphatase 4A3 (PTP4A3) Promotes Vascular Endothelial Growth Factor Signaling and Enables Endothelial Cell Motility*

G. Homanics, J. Lazo, B. Pitt, 2014, The Journal of Biological Chemistry.

Stem cells in lung biology.

L. Ortiz, B. Pitt, 2004, American journal of physiology. Lung cellular and molecular physiology.

Epithelial expression of TIMP-1 does not alter sensitivity to bleomycin-induced lung injury in C57BL/6 mice.

L. Ortiz, G. Hoyle, B. Pitt, 2008, American journal of physiology. Lung cellular and molecular physiology.

Targeted delivery of oligodeoxynucleotides to mouse lung endothelial cells in vitro and in vivo.

Simon C Watkins, S. Kennel, B. Pitt, 2005, Molecular therapy : the journal of the American Society of Gene Therapy.

A biohybrid artificial lung prototype with active mixing of endothelialized microporous hollow fibers

D. Stolz, W. Federspiel, W. Wagner, 2010, Biotechnology and bioengineering.

Inhibiting geranylgeranylation blocks growth and promotes apoptosis in pulmonary vascular smooth muscle cells.

A. Vasudevan, S. Sebti, A. Hamilton, 1998, American journal of physiology. Lung cellular and molecular physiology.

FXR-mediated regulation of eNOS expression in vascular endothelial cells.

F. He, Ramalinga Kuruba, B. Pitt, 2008, Cardiovascular research.

Improved spatial resolution of matrix-assisted laser desorption/ionization imaging of lipids in the brain by alkylated derivatives of 2,5-dihydroxybenzoic acid.

H. Bayır, L. J. Sparvero, B. Pitt, 2014, Rapid communications in mass spectrometry : RCM.

Altered oxidative stress responses and increased type I collagen expression in bicuspid aortic valve patients.

Julie A. Phillippi, Julie A Phillippi, B. Pitt, 2010, The Annals of thoracic surgery.

Antisense oligodeoxynucleotide to inducible nitric oxide synthase inhibits nitric oxide synthesis in rat pulmonary artery smooth muscle cells in culture.

T. Billiar, D. Geller, R. Simmons, 1993, Surgery.

Cationic lipids enhance siRNA-mediated interferon response in mice.

F. He, B. Pitt, Song Li, 2005, Biochemical and biophysical research communications.

Fetal gene therapy Retrovirus-mediated gene therapy to fetal lung

P. Robbins, B. Pitt, 1996 .

Enhanced Sensitivity to Oxidative Stress in Cultured Embryonic Cells from Transgenic Mice Deficient in Metallothionein I and II Genes (*)

J. Lazo, B. Pitt, Dana Dellapiazza, 1995, The Journal of Biological Chemistry.

Downregulation of Endothelin-1 by Farnesoid X Receptor in Vascular Endothelial Cells

Simon C Watkins, F. He, Yu Jiang, 2006, Circulation research.

FXR-mediated regulation of angiotensin type 2 receptor expression in vascular smooth muscle cells.

T. Billiar, F. He, Ramalinga Kuruba, 2008, Cardiovascular research.

Coordinated Regulation of Dimethylarginine Dimethylaminohydrolase-1 and Cationic Amino Acid Transporter-1 by Farnesoid X Receptor in Mouse Liver and Kidney and Its Implication in the Control of Blood Levels of Asymmetric Dimethylarginine

Youhua Liu, Ramalinga Kuruba, S. Poloyac, 2009, Journal of Pharmacology and Experimental Therapeutics.

Coordination of mucociliary transport in human trachea and intrapulmonary airways.

R. Albert, D. Spektor, B. Pitt, 1981, Journal of applied physiology: respiratory, environmental and exercise physiology.

Cytochrome c/cardiolipin relations in mitochondria: a kiss of death.

P. Kochanek, H. Bayır, P. Wipf, 2009, Free radical biology & medicine.

Effects of changes in pulmonary perfusion and surface area on endothelial ace activity

B. Pitt, L. Reid, G. Lister, 2006, Annals of Biomedical Engineering.

Correlation between lung and plasma angiotensin converting enzyme and the hypotensive effect of captopril in conscious rabbits.

C. N. Gillis, B. Pitt, X. Chen, 1984, The Journal of pharmacology and experimental therapeutics.

WISP1-αvβ3 integrin signaling positively regulates TLR-triggered inflammation response in sepsis induced lung injury

T. Billiar, B. Pitt, Zhixia Chen, 2016, Scientific Reports.

Cell-Surface Protein Disulfide Isomerase Is Required for Transnitrosation of Metallothionein by S-Nitroso-Albumin in Intact Rat Pulmonary Vascular Endothelial Cells

Simon C Watkins, K. Wasserloos, B. Pitt, 2006, Experimental biology and medicine.

Mass-spectrometric analysis of hydroperoxy- and hydroxy-derivatives of cardiolipin and phosphatidylserine in cells and tissues induced by pro-apoptotic and pro-inflammatory stimuli.

P. Kochanek, H. Bayır, J. Greenberger, 2009, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Induction of lipopolysaccharide-binding protein gene expression in cultured rat pulmonary artery smooth muscle cells by interleukin 1 beta.

G. Su, H. Wong, T. Billiar, 1995, American journal of respiratory cell and molecular biology.

Depression of pulmonary metabolic function by cardiopulmonary bypass procedures increases levels of circulating norepinephrine.

C. N. Gillis, B. Pitt, G. Hammond, 1984, The Annals of thoracic surgery.

IL-1 beta stimulates superoxide and delayed peroxynitrite production by pulmonary vascular smooth muscle cells.

B. Pitt, B. Johnson, Y. M. Kim, 1996, The American journal of physiology.

Cytoplasmic metallothionein overexpression protects NIH 3T3 cells from tert-butyl hydroperoxide toxicity.

Simon C Watkins, J. Lazo, B. Pitt, 1994, The Journal of biological chemistry.

The fate of circulating amines within the pulmonary circulation.

C. N. Gillis, B. Pitt, C. Gillis, 1982, Annual review of physiology.

Selective effect of microembolization on pulmonary removal of biogenic amines.

C. N. Gillis, B. Pitt, G. Hammond, 1982, Journal of applied physiology: respiratory, environmental and exercise physiology.

mitochondrial pathway for biosynthesis of lipid mediators

J. Klein-Seetharaman, P. Kochanek, H. Bayır, 2014, Nature chemistry.

A role for zinc in regulating hypoxia-induced contractile events in pulmonary endothelium.

Simon C Watkins, C. S. St. Croix, B. Pitt, 2011, American journal of physiology. Lung cellular and molecular physiology.

Probing the Structural Basis of Zn2+ Regulation of the Epithelial Na+ Channel*

M. Myerburg, B. Pitt, K. L. Winarski, 2012, The Journal of Biological Chemistry.

Loss and Degradation of Enzyme-bound Heme Induced by Cellular Nitric Oxide Synthesis (*)

J. Lancaster, B. Pitt, W. Watkins, 1995, The Journal of Biological Chemistry.

Bifunctional anti/prooxidant potential of metallothionenin: redox signaling of copper binding and release.

J. Lazo, B. Pitt, V. Tyurin, 1999, Antioxidants & redox signaling.

Redox regulation of copper-metallothionein.

J. Lazo, B. Pitt, Y. Tyurina, 1999, Archives of biochemistry and biophysics.

"Only a Life Lived for Others Is Worth Living": Redox Signaling by Oxygenated Phospholipids in Cell Fate Decisions.

Simon C Watkins, I. Bahar, H. Bayır, 2017, Antioxidants & redox signaling.

Nitric oxide-induced changes in intracellular zinc homeostasis are mediated by metallothionein/thionein.

C. S. St. Croix, K. Wasserloos, B. Pitt, 2002, American journal of physiology. Lung cellular and molecular physiology.

Inhibition of LPS- and CpG DNA-induced TNF-α response by oxidized phospholipids

B. Pitt, W. Xie, Lijuan Yang, 2004 .

Beagle puppy model of perinatal cerebral insults. Cerebral blood flow changes and intraventricular hemorrhage evoked by hypoxemia.

W. Stewart, L. Ment, C. Duncan, 1986, Journal of neurosurgery.

Nitric oxide-induced nuclear translocation of the metal responsive transcription factor, MTF-1 is mediated by zinc release from metallothionein.

X. Tang, C. S. St. Croix, M. Stitt, 2006, Vascular pharmacology.

Nitric oxide and zinc homeostasis in acute lung injury.

Simon C Watkins, C. S. St. Croix, B. Pitt, 2005, Proceedings of the American Thoracic Society.

Role of zinc in pulmonary endothelial cell response to oxidative stress.

C. S. St. Croix, K. Wasserloos, B. Pitt, 2001, American journal of physiology. Lung cellular and molecular physiology.

Metallothionein, nitric oxide and zinc homeostasis in vascular endothelial cells.

C. S. St. Croix, K. Wasserloos, B. Pitt, 2000, The Journal of nutrition.

Expression of Pulmonary Metallothionein Genes in Late Gestational Lambs

J. Lazo, B. Pitt, S. Kuo, 1992, Pediatric Research.

Metallothionein-induced zinc partitioning exacerbates hyperoxic acute lung injury.

Octavia M Peck Palmer, D. Angus, J. Alcorn, 2013, American journal of physiology. Lung cellular and molecular physiology.

Redox sensor function of metallothioneins.

B. Pitt, V. Tyurin, V. Kagan, 2002, Methods in enzymology.

Sequences in Intron 51 of the von Willebrand Factor Gene Target Promoter Activation to a Subset of Lung Endothelial Cells in Transgenic Mice*

Simon C Watkins, M. Stitt, K. Wasserloos, 2008, Journal of Biological Chemistry.

Faculty Opinions recommendation of The zinc transporter SLC39A13/ZIP13 is required for connective tissue development; its involvement in BMP/TGF-beta signaling pathways.

B. Pitt, 2008 .

A mitochondria-targeted inhibitor of cytochrome c peroxidase mitigates radiation induced death

J. Klein-Seetharaman, Hong Wang, H. Bayır, 2011, Nature communications.

Effect of immune response on gene transfer to the lung via systemic administration of cationic lipidic vectors.

Simon C Watkins, B. Pitt, Leaf Huang, 1999, American journal of physiology. Lung cellular and molecular physiology.

Nitrosative Stress Inhibits the Aminophospholipid Translocase Resulting in Phosphatidylserine Externalization and Macrophage Engulfment

H. Bayır, B. Fadeel, N. Konduru, 2007, Journal of Biological Chemistry.

S1P2 receptor-dependent Rho-kinase activation mediates vasoconstriction in the murine pulmonary circulation induced by sphingosine 1-phosphate.

B. Pitt, B. McVerry, W. Szczepaniak, 2010, American journal of physiology. Lung cellular and molecular physiology.

Culture of pulmonary microvascular smooth muscle cells from intraacinar arteries of the rat: characterization and inducible production of nitric oxide.

C. Lowenstein, B. Pitt, D. Nakayama, 1994, American journal of respiratory cell and molecular biology.

Integrins inhibit LPS-induced DNA strand breakage in cultured lung endothelial cells.

Simon C Watkins, R. Mannix, J. Lazo, 1996, The American journal of physiology.

The effect of nitric oxide on fetal pulmonary artery smooth muscle growth.

T. Billiar, R. Simmons, B. Pitt, 1995, The Journal of surgical research.

Thioredoxin and lipoic acid catalyze the denitrosation of low molecular weight and protein S-nitrosothiols.

T. Billiar, D. Gius, B. Pitt, 2005, Journal of the American Chemical Society.

The Catabolic Fate of Nitric Oxide

A. Kanai, L. Birder, B. Pitt, 2002, The Journal of Biological Chemistry.

Effect of orally administered orciprenaline on tracheobronchial mucociliary clearance.

D. Spektor, B. Pitt, D. Yeates, 1986, European journal of respiratory diseases.

SITE- AND MECHANISM-DIRECTED INTERVENTIONS FOR TISSUE FREE RADICAL INJURY

M. Tarpey, B. Freeman, B. Pitt, 2000 .

Gene Therapy and Endothelial Cell Targeting for Cancer

J. Lazo, Candace S. Johnson, B. Pitt, 1994, Annals of the New York Academy of Sciences.

Nitric Oxide–Mediated Zinc Release Contributes to Hypoxic Regulation of Pulmonary Vascular Tone

Simon C Watkins, C. S. St. Croix, Karanee Leelavanichkul, 2008, Circulation research.

Apparent kinetics of angiotensin converting enzyme: hydrolysis of [3H]benzoyl-phenylalanyl-alanyl-proline in the isolated perfused lung.

C. N. Gillis, B. Pitt, J. Ashton, 1985, The Journal of pharmacology and experimental therapeutics.

Transcriptional regulation of iNOS by IL-1 beta in cultured rat pulmonary artery smooth muscle cells.

C. Lowenstein, H. Wong, T. Billiar, 1996, The American journal of physiology.

Tetrahydrobiopterin synthesis and inducible nitric oxide production in pulmonary artery smooth muscle.

H. Kagamiyama, T. Billiar, D. Geller, 1994, The American journal of physiology.

Effect of nitric oxide on heme metabolism in pulmonary artery endothelial cells.

T. Billiar, B. Pitt, Y. M. Kim, 1996, The American journal of physiology.

Nitric oxide and intracellular heme.

J. Lancaster, B. Pitt, W. Watkins, 1995, Advances in pharmacology.

Serotonin increases DNA synthesis in rat proximal and distal pulmonary vascular smooth muscle cells in culture.

R. Blakely, B. Pitt, I. Reynolds, 1994, The American journal of physiology.

Collagen is a survival factor against LPS-induced apoptosis in cultured sheep pulmonary artery endothelial cells.

R. Mannix, J. Lazo, B. Pitt, 1995, The American journal of physiology.

Angiogenesis and morphogenesis of murine fetal distal lung in an allograft model.

V. Starnes, B. Pitt, M. Schwarz, 2000, American journal of physiology. Lung cellular and molecular physiology.

Prolonged gene expression in mouse lung endothelial cells following transfection with Epstein–Barr virus-based episomal plasmid

B. Pitt, O. Mazda, E. Satoh, 2003, Gene Therapy.

Lipid-mediated delivery of oligonucleotide to pulmonary endothelium.

Simon C Watkins, D. Stolz, B. Pitt, 2002, American journal of respiratory cell and molecular biology.

Complex Roles of CpG in Liposomal Delivery of DNA and Oligonucleotides

B. Pitt, Song Li, Annette Wilson, 2002, Bioscience reports.

Roles of Platelet-Activating Factor and Thromboxane in Group B Streptococcus-Induced Pulmonary Hypertension in Piglets

C. N. Gillis, B. Pitt, J. Pinheiro, 1989, Pediatric Research.

Inhibition of LPS- and CpG DNA-induced TNF- (cid:1) response by oxidized phospholipids

B. Pitt, W. Xie, Lijuan Yang, 2004 .

The Catabolic Fate of Nitric Oxide THE NITRIC OXIDE OXIDASE AND PEROXYNITRITE REDUCTASE ACTIVITIES OF CYTOCHROME OXIDASE*

A. Kanai, L. Birder, B. Pitt, 2002 .

Bleomycin: a pharmacologic tool in the study of the pathogenesis of interstitial pulmonary fibrosis.

J. Lazo, S. Sebti, B. Pitt, 1990, Pharmacology & therapeutics.

Cytokines and lipopolysaccharide induce nitric oxide synthase in cultured rat pulmonary artery smooth muscle.

C. Lowenstein, T. Billiar, D. Geller, 1992, American journal of respiratory cell and molecular biology.

in cultured rat pulmonary vascular cells Cytoprotective effects of albumin, nitrosated or reduced,

K. Wasserloos, B. Pitt, Jing Xu, 2016 .

Cytoprotective effects of albumin, nitrosated or reduced, in cultured rat pulmonary vascular cells.

J. Xu, K. Wasserloos, B. Pitt, 2011, American journal of physiology. Lung cellular and molecular physiology.

Signal transduction pathways of IL-1β-mediated iNOS in pulmonary vascular smooth muscle cells

S. Sebti, A. Hamilton, B. Pitt, 2001 .

Signal transduction pathways of IL-1 b -mediated iNOS in pulmonary vascular smooth muscle cells

S. Sebti, A. Hamilton, B. Pitt, 2001 .

Nitric oxide produced by cytokine-activated pulmonary artery smooth muscle cells is cytotoxic to cocultured endothelium.

T. Billiar, R. Simmons, B. Pitt, 1996, Surgery.

Nitric oxide decreases the sensitivity of pulmonary endothelial cells to LPS-induced apoptosis in a zinc-dependent fashion

C. S. St. Croix, M. Stitt, K. Wasserloos, 2004, Molecular and Cellular Biochemistry.

Redirecting adenovirus to pulmonary endothelium by cationic liposomes

B. Pitt, P. Robbins, S. Li, 2002, Gene Therapy.

Nitric oxide decreases the sensitivity of pulmonary endothelial cells to LPS-induced apoptosis in a zinc-dependent fashion.

M. Stitt, K. Wasserloos, B. Pitt, 2002 .

Separation of prostaglandin E1 from its major metabolites. Application of the technique to measure first-pass clearance of PGE1 in the pulmonary and cerebral circulations of the anesthetized dog.

C. N. Gillis, B. Pitt, R. Altiere, 1981, Biochemical pharmacology.

The Peroxynitrite Reductase Activity of Cytochrome cOxidase Involves a Two-electron Redox Reaction at the Hemea 3-CuB Site*

B. Pitt, L. Pearce, J. Peterson, 1999, The Journal of Biological Chemistry.

CpG DNA-mediated immune response in pulmonary endothelial cells.

B. Pitt, Song Li, T. Stevens, 2004, American journal of physiology. Lung cellular and molecular physiology.

Mechanical Ventilation with Moderate Tidal Volume Exacerbates Extrapulmonary Sepsis-Induced Lung Injury via IL33-WISP1 Signaling Pathway

T. Billiar, H. Turnquist, B. Pitt, 2020, Shock.

The IL-33-ST2 Pathway Contributes to Ventilator-Induced Lung Injury in Septic Mice in a Tidal Volume-Dependent Manner.

T. Billiar, H. Turnquist, B. Pitt, 2019, Shock.

Prenyltransferase inhibitors block superoxide production by pulmonary vascular smooth muscle.

S. Sebti, A. Hamilton, B. Pitt, 2000, American journal of physiology. Lung cellular and molecular physiology.

Identification of respiratory complexes I and III as mitochondrial sites of damage following exposure to ionizing radiation and nitric oxide.

J. Greenberger, B. Pitt, M. Epperly, 2001, Nitric oxide : biology and chemistry.

Adenoviral transfer of the inducible nitric oxide synthase gene blocks endothelial cell apoptosis.

T. Billiar, I. Kovesdi, B. Pitt, 1997, Surgery.

A critical role for increased labile zinc in reducing sensitivity of cultured sheep pulmonary artery endothelial cells to LPS-induced apoptosis.

K. Wasserloos, B. Pitt, V. Kagan, 2012, American journal of physiology. Lung cellular and molecular physiology.

Nitric oxide and zinc homeostasis in pulmonary endothelium

C. S. St. Croix, K. Wasserloos, B. Pitt, 2010, Annals of the New York Academy of Sciences.

Protein phosphorylation in cultured endothelial cells

P. Greengard, A. Nairn, J. Lazo, 1986, Journal of cellular physiology.

Desensitization of 5HT2 Receptors by Protein Kinase C Activation in Distal Pulmonary Vascular Smooth Muscle Cells in Culture

S. Sebti, B. Pitt, I. Reynolds, 1994, Microcirculation.

Oxidation of phosphatidylserine: a mechanism for plasma membrane phospholipid scrambling during apoptosis?

Qing Zhao, P. Quinn, B. Pitt, 2004, Biochemical and biophysical research communications.

E14 Damage associated molecular pattern molecules (DAMPs) redox and autophagy

L. Butterfield, M. Lotze, S. Plevy, 2010 .

Beagle pup model of brain injury: regional cerebral blood flow and cerebral prostaglandins.

W. Stewart, L. Ment, C. Duncan, 1987, Journal of neurosurgery.

Mechanical ventilation enhances extrapulmonary sepsis-induced lung injury: role of WISP1–αvβ5 integrin pathway in TLR4-mediated inflammation and injury

T. Billiar, B. Pitt, Tunliang Li, 2018, Critical Care.

Caveolae-Dependent and -Independent Uptake of Albumin in Cultured Rodent Pulmonary Endothelial Cells

Simon C Watkins, Janet S. Lee, D. Stolz, 2013, PloS one.

CHAPTER 15 – THE USE OF BLEOMYCIN IN MODEL SYSTEMS TO STUDY THE PATHOGENESIS OF INTERSTITIAL PULMONARY FIBROSIS

J. Lazo, B. Pitt, D. Hoyt, 1993 .

TGF-beta regulates production of NO in pulmonary artery smooth muscle cells by inhibiting expression of NOS.

D. Geller, K. Wasserloos, B. Pitt, 1995, The American journal of physiology.

Phenoxyl radicals of etoposide (VP-16) can directly oxidize intracellular thiols: protective versus damaging effects of phenolic antioxidants.

H. Claycamp, P. Quinn, B. Pitt, 1995, Toxicology and applied pharmacology.

Inhibiting geranylgeranylation blocks growth and promotes apoptosis in pulmonary vascular smooth muscle cells.

A. Vasudevan, S. Sebti, A. Hamilton, 1998, The American journal of physiology.

Iron-induced remodeling in cultured rat pulmonary artery endothelial cells

N. Gorbunov, N. Gurusamy, B. Pitt, 2011, BioMetals.

S 1 P 2 receptor-dependent Rho-kinase activation mediates vasoconstriction in the murine pulmonary circulation induced by sphingosine 1-phosphate

B. Pitt, B. McVerry, W. Szczepaniak, 2010 .

Neutrophil elastase is needed for neutrophil emigration into lungs in ventilator-induced lung injury.

A. M. Houghton, S. Shapiro, B. Pitt, 2008, American journal of respiratory cell and molecular biology.

Oxidative lipidomics of hyperoxic acute lung injury: mass spectrometric characterization of cardiolipin and phosphatidylserine peroxidation.

Simon Watkins, Simon C Watkins, Peter Wipf, 2010, American journal of physiology. Lung cellular and molecular physiology.

Methods for retrovirus-mediated gene transfer to fetal lung.

B. Pitt, M. Schwarz, R. Bland, 1997, Methods in molecular medicine.

Acute, sublethal cyanide poisoning in mice is ameliorated by nitrite alone: complications arising from concomitant administration of nitrite and thiosulfate as an antidotal combination.

B. Pitt, Leah K Cambal, L. Pearce, 2011, Chemical research in toxicology.

HSP induction inhibits iNOS mRNA expression and attenuates hypotension in endotoxin-challenged rats.

H. Wong, K. Wasserloos, B. Pitt, 1996, The American journal of physiology.

Vascular Gene Transfer of the Human Inducible Nitric Oxide Synthase: Characterization of Activity and Effects on Myointimal Hyperplasia

Simon C Watkins, P. Robbins, T. Billiar, 1996, Molecular medicine.

Biphasic stimulation of prostacyclin by endogenous nitric oxide (NO) in endothelial cells transfected with inducible NO synthase.

J. Roberts, S. Davidge, B. Pitt, 1999, General pharmacology.

Oxidative Lipidomics of γ-Radiation-Induced Lung Injury: Mass Spectrometric Characterization of Cardiolipin and Phosphatidylserine Peroxidation

J. Greenberger, K. Wasserloos, B. Pitt, 2011, Radiation research.

PTP4A3 phosphatase promotes VEGF signaling and enables endothelial cell motility

G. Homanics, J. Lazo, B. Pitt, 2013 .

Integrin activation protects pulmonary endothelial cells from the genotoxic effects of bleomycin.

J. Lazo, M. Gerritsen, B. Pitt, 1997, The American journal of physiology.

Depressed prostaglandin E1 and 5-hydroxytryptamine removal in patients with adult respiratory distress syndrome.

C. N. Gillis, B. Pitt, G. Hammond, 1986, The American review of respiratory disease.

Postnatal growth of the sheep lung: A morphometric study

B. Pitt, L. Reid, G. Lister, 1988, The Anatomical record.

Metabolic functions of the lung and systemic vasoregulation.

B. Pitt, 1984, Federation proceedings.

Specific fluorogenic probes for ozone in biological and atmospheric samples.

C. S. St. Croix, B. Pitt, G. Leikauf, 2009, Nature chemistry.

The protein thiol metallothionein as an antioxidant and protectant against antineoplastic drugs.

E S Woo, J. Lazo, B. Pitt, 1998, Chemico-biological interactions.

Interaction of carbon monoxide and cyanide on cerebral circulation and metabolism.

R. Traystman, E. Radford, B. Pitt, 1979, Archives of environmental health.

Zinc in innate and adaptive tumor immunity

L. Butterfield, M. Lotze, B. Pitt, 2010, Journal of Translational Medicine.

Transforming Growth Factor-α Gene Expression in Late-Gestation Fetal Rat Lung

B. Pitt, J. Hunt, P. Davies, 1992, Pediatric Research.

Toll-like Receptor 4-Myeloid Differentiation Factor 88 Signaling Contributes to Ventilator-induced Lung Injury in Mice

W. Chao, B. Pitt, G. Leikauf, 2010, Anesthesiology.

Mitochondrial targeting of electron scavenging antioxidants: Regulation of selective oxidation vs random chain reactions.

J. Klein-Seetharaman, H. Bayır, P. Wipf, 2009, Advanced drug delivery reviews.

Correlation of pulmonary ACE activity and capillary surface area during postnatal development.

B. Pitt, L. Reid, G. Lister, 1987, Journal of applied physiology.

Nitric oxide inhibits lipopolysaccharide-induced apoptosis in pulmonary artery endothelial cells.

Simon C Watkins, T. Billiar, J. Engelhardt, 1998, American journal of physiology. Lung cellular and molecular physiology.

Targeted delivery of therapeutic oligonucleotides to pulmonary circulation.

F. He, B. Pitt, Song Li, 2005, Advances in genetics.

The inhibitory role of CpG immunostimulatory motifs in cationic lipid vector-mediated transgene expression in vivo.

Y. Tan, B. Pitt, Leaf Huang, 1999, Human gene therapy.

Nitric oxide inhibits lipopolysaccharide-induced apoptosis in pulmonary artery endothelial cells.

Simon C Watkins, T. Billiar, J. Engelhardt, 1998, The American journal of physiology.

Role of metallothionein in nitric oxide signaling as revealed by a green fluorescent fusion protein.

A. Kanai, M. Stitt, K. Wasserloos, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Metallothioneins and cell death by anticancer drugs.

J. Lazo, B. Pitt, 1995, Annual review of pharmacology and toxicology.

Zinc Homeostasis in Lung

B. Pitt, C. S. Croix, Karla A. Wasserloos, 2015 .

Functional role of intracellular labile zinc in pulmonary endothelium

C. S. St. Croix, B. Pitt, C. S. Croix, 2012, Pulmonary circulation.

Retrovirus-mediated gene transfer in lungs of living fetal sheep.

S. A. Watkins, P. Robbins, K. Albertine, 1995, Gene therapy.

Physiology, reductionism, and translational medicine: the right mix.

J. Christman, S. Gunst, M. Matthay, 2011, American journal of physiology. Lung cellular and molecular physiology.

Comparison of pulmonary and extrapulmonary extraction of biogenic amines.

C. N. Gillis, B. Pitt, G. Hammond, 1982, Journal of applied physiology: respiratory, environmental and exercise physiology.

Influence of the lung on arterial levels of endogenous prostaglandins E and F.

C. N. Gillis, B. Pitt, G. Hammond, 1981, Journal of applied physiology: respiratory, environmental and exercise physiology.

Kinetics of pulmonary angiotensin-converting enzyme activity in conscious developing lambs.

B. Pitt, G. Lister, 1984, Journal of applied physiology: respiratory, environmental and exercise physiology.

The heat-shock response attenuates lipopolysaccharide-mediated apoptosis in cultured sheep pulmonary artery endothelial cells.

Simon C Watkins, R. Mannix, H. Wong, 1996, American journal of respiratory cell and molecular biology.

Pulmonary extraction of [3H]bupivacaine: modification by dose, propranolol and interaction with [14C]5-hydroxytryptamine.

B. Pitt, P. Rothstein, J. Cole, 1987, The Journal of pharmacology and experimental therapeutics.

Cardiopulmonary interactions in the infant with congenital cardiac disease.

B. Pitt, G. Lister, 1983, Clinics in chest medicine.

Pulmonary metabolic function can serve as a monitor for lung preservation.

C. N. Gillis, B. Pitt, G. Hammond, 1986, The Journal of heart transplantation.

The HIV protease inhibitor Saquinavir attenuates sepsis-induced acute lung injury and promotes M2 macrophage polarization via targeting matrix metalloproteinase-9

T. Billiar, B. Pitt, Zhixia Chen, 2021, Cell Death and Disease.

Beagle pup model of perinatal asphyxia: nimodipine studies.

W. Stewart, L. Ment, C. Duncan, 1987, Stroke.

Beagle puppy model of perinatal cerebral infarction. Regional cerebral prostaglandin changes during acute hypoxemia.

W. Stewart, L. Ment, C. Duncan, 1986, Journal of neurosurgery.

Lung redox homeostasis: emerging concepts.

A. Choi, C. Dawson, A. Fisher, 2000, American journal of physiology. Lung cellular and molecular physiology.

Depressed pulmonary removal of [3H]prostaglandin E1 after prolonged cardiopulmonary bypass.

C. N. Gillis, B. Pitt, G. Hammond, 1982, Journal of applied physiology: respiratory, environmental and exercise physiology.

Iron-induced remodeling in cultured rat pulmonary artery endothelial cells

N. Gorbunov, N. Gurusamy, B. Pitt, 2012, BioMetals.

Enhanced apoptosis in metallothionein null cells.

J. Lazo, B. Pitt, Y. Kondo, 1997, Molecular pharmacology.

Pulmonary arterial smooth muscle cells modulate cytokine- and LPS-induced cytotoxicity in endothelial cells.

B. Pitt, B. Johnson, P. Davies, 2000, American journal of physiology. Lung cellular and molecular physiology.

Multimodal optical imaging.

Simon C Watkins, William A Suk, Cindy Lawler, 2003, American journal of physiology. Lung cellular and molecular physiology.

Actin-containing sera from patients with adult respiratory distress syndrome are toxic to sheep pulmonary endothelial cells.

Simon C Watkins, K. Gibson, K. Wasserloos, 2000, American journal of respiratory and critical care medicine.

WNT1-inducible signaling pathway protein 1 contributes to ventilator-induced lung injury.

M. You, T. Oury, T. Billiar, 2012, American journal of respiratory cell and molecular biology.

Polycations increase the efficiency of adenovirus-mediated gene transfer to epithelial and endothelial cells in vitro

B. Pitt, SM Arcasoy, JD Latoche, 1997, Gene Therapy.

S-Nitrosoalbumin–Mediated Relaxation Is Enhanced by Ascorbate and Copper: Effects in Pregnancy and Preeclampsia Plasma

Robert N. Taylor, C. Hubel, B. Pitt, 2005, Hypertension.

LPS-induced decrease in intracellular labile zinc, [Zn]i, contributes to apoptosis in cultured sheep pulmonary artery endothelial cells.

C. S. St. Croix, K. Wasserloos, B. Pitt, 2011, American journal of physiology. Lung cellular and molecular physiology.

Inhibition of LPS- and CpG DNA-induced TNF-alpha response by oxidized phospholipids.

B. Pitt, W. Xie, Lijuan Yang, 2004, American journal of physiology. Lung cellular and molecular physiology.

Beagle puppy model of perinatal cerebral infarction. Acute changes in regional cerebral prostaglandins during hemorrhagic hypotension.

W. Stewart, L. Ment, C. Duncan, 1985, Journal of neurosurgery.

Beagle puppy model of perinatal cerebral infarction. Acute changes in cerebral blood flow and metabolism during hemorrhagic hypotension.

W. Stewart, L. Ment, A. Rescigno, 1985, Journal of neurosurgery.

Nickel mobilizes intracellular zinc to induce metallothionein in human airway epithelial cells.

Antonia A. Nemec, K. Wasserloos, B. Pitt, 2009, American journal of respiratory cell and molecular biology.

USMLE step 1

John S. Lazo, Bruce R. Pitt, Joseph C. Glorioso, 1999 .

Mapping of phospholipids by MALDI imaging (MALDI-MSI): realities and expectations.

P. Kochanek, H. Bayır, J. Long, 2012, Chemistry and physics of lipids.

Subcellular localization mediated functioning of metallothionein: Protection against oxygen radicals and anticancer agents

J. Lazo, B. Pitt, E. S. Woo, 1999 .

Randomized indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight infants.

R. Ehrenkranz, W. Stewart, L. Ment, 1985, The Journal of pediatrics.

Biosynthesis of oxidized lipid mediators via lipoprotein-associated phospholipase A2 hydrolysis of extracellular cardiolipin induces endothelial toxicity.

Bill B. Chen, Yutong Zhao, R. Mallampalli, 2016, American journal of physiology. Lung cellular and molecular physiology.

Complex regulation of iNOS in lung.

C. S. St. Croix, B. Pitt, C. S. St Croix, 2002, American journal of respiratory cell and molecular biology.

Fluorescence resonance energy transfer-based assays for the real-time detection of nitric oxide signaling.

Simon C Watkins, C. S. St. Croix, M. Stitt, 2005, Methods in enzymology.

Effect of immune response on gene transfer to the lung via systemic administration of cationic lipidic vectors.

Simon C Watkins, L. Wang, B. Pitt, 1999, American Journal of Physiology.

Transforming growth factor-alpha gene expression in late-gestation fetal rat lung.

B. Pitt, J. Hunt, P. Davies, 1992, Pediatric research.

Overexpression of metallothionein decreases sensitivity of pulmonary endothelial cells to oxidant injury.

Simon C Watkins, R. Mannix, J. Lazo, 1997, American journal of physiology. Lung cellular and molecular physiology.

Translocation of protein kinase C is associated with inhibition of 5-HT uptake by cultured endothelial cells.

J. Lazo, B. Pitt, C. L. Myers, 1989, The American journal of physiology.

Overexpression of metallothionein decreases sensitivity of pulmonary endothelial cells to oxidant injury

Simon C Watkins, R. Mannix, J. Lazo, 1997 .

Protein Kinase C Modulation of Serotonin Transport by Pulmonary Endothelial Cells

B. Pitt, 1991 .

TRANSPORT BY PULMONARY ENDOTHELIAL CELLS

B. Pitt, 1991 .

Activation of protein kinase C inhibits extraction of serotonin by perfused rat lung in situ.

B. Pitt, W. Weng, 1990, The American journal of physiology.

Pulmonary angiotensin-converting enzyme kinetics after acute lung injury in the rabbit.

C. N. Gillis, B. Pitt, A. M. Havill, 1988, Journal of applied physiology.

Selective effect of phorbol ester on serotonin removal and ACE activity in rabbit lungs.

B. Pitt, C. L. Myers, 1988, Journal of applied physiology.

The HIV protease inhibitor Saquinavir attenuates sepsis-induced acute lung injury and promotes M2 macrophage polarization via targeting matrix metalloproteinase-9

T. Billiar, B. Pitt, Zhixia Chen, 2021, Cell death & disease.

Mass‐spectrometry based oxidative lipidomics and lipid imaging: applications in traumatic brain injury

P. Kochanek, H. Bayır, L. J. Sparvero, 2010, Journal of neurochemistry.

Orai1 Determines Calcium Selectivity of an Endogenous TRPC Heterotetramer Channel

S. Uhlig, C. S. St. Croix, B. Pitt, 2012, Circulation research.

Effects of drugs on mucociliary transport in the trachea and bronchial airways.

D. Spektor, B. Pitt, G. Leikauf, 1981, Chest.

Nitric oxide-dependent pro-oxidant and pro-apoptotic effect of metallothioneins in HL-60 cells challenged with cupric nitrilotriacetate.

P. Quinn, B. Pitt, Y. Tyurina, 2001, The Biochemical journal.

Resolution of impaired pulmonary function and pulmonary hypertension after phorbol ester administration in rabbits.

C. N. Gillis, B. Pitt, A. M. Havill, 1989, The American review of respiratory disease.

Racial differences in biologic predictors of severe asthma: Data from the Severe Asthma Research Program.

W. Busse, E. Bleecker, E. Israel, 2010, The Journal of allergy and clinical immunology.

Plasma from Preeclamptic Women Causes a Rapid, Calcium-Sensitive Release of Nitric Oxide from Vascular Smooth Muscle Cells

S. Davidge, P. Baker, B. Pitt, 1997 .

Contribution of glutathione and metallothioneins to protection against copper toxicity and redox cycling: quantitative analysis using MT+/+ and MT-/- mouse lung fibroblast cells.

Qing Zhao, C. S. St. Croix, B. Pitt, 2002, Chemical research in toxicology.

Faculty Opinions recommendation of Lipocalin 2 is required for pulmonary host defense against Klebsiella infection.

B. Pitt, 2009 .

Perinatal Outcomes and Unconventional Natural Gas Operations in Southwest Pennsylvania

B. Goldstein, Y. Sadovsky, E. Talbott, 2015, PloS one.

Pulmonary metabolic function in the awake lamb: effect of development and hypoxia.

B. Pitt, G. Lister, 1983, Journal of applied physiology: respiratory, environmental and exercise physiology.

Induced nitric oxide inhibits IL-6-induced stat3 activation and type II acute phase mRNA expression.

M. Kibbe, D. Tweardy, T. Billiar, 2000, Shock.

Interpretation of metabolic function of the lung. Influence of perfusion, kinetics, and injury.

B. Pitt, G. Lister, 1989, Clinics in chest medicine.

CFTR trafficking and signaling in respiratory epithelium.

B. Pitt, 2001, American journal of physiology. Lung cellular and molecular physiology.

Erratum: Specific fluorogenic probes for ozone in biological and atmospheric samples (Nature Chemistry (2009) 1 (316-321))

B. Pitt, G. Leikauf, C. S. Croix, 2010 .

EB2000 symposium report Lung redox homeostasis: emerging concepts

A. Choi, C. Dawson, A. Fisher, 2000 .

Inducible Nitric Oxide Synthase Contributes to Immune Dysfunction Following Trauma

T. Billiar, B. Pitt, H. Pape, 2012, Shock.

Antioxidant and antiapoptotic function of metallothioneins in HL-60 cells challenged with copper nitrilotriacetate.

B. Pitt, Y. Tyurina, V. Tyurin, 2000, Chemical research in toxicology.

Racial differences in biologic predictors of severe asthma: Data from the Severe Asthma Research Program.

W. Busse, E. Bleecker, E. Israel, 2010, The Journal of allergy and clinical immunology.

IL-33-mediated IL-13 secretion by ST2+ Tregs controls inflammation after lung injury.

J. Alcorn, U. Chandran, A. Chakka, 2019, JCI insight.

Metallothionein-induced zinc partitioning exacerbates hyperoxic acute lung injury.

D. Angus, J. Alcorn, D. Stolz, 2013, American journal of physiology. Lung cellular and molecular physiology.

Nitric oxide and zinc homeostasis in pulmonary endothelium

K. Wasserloos, B. Pitt, R. Cao, 2010, Annals of the New York Academy of Sciences.

Nitric Oxide–Mediated Zinc Release Contributes to Hypoxic Regulation of Pulmonary Vascular Tone

Simon C Watkins, Karanee Leelavanichkul, K. Wasserloos, 2008, Circulation research.

WNT1-inducible signaling pathway protein 1 contributes to ventilator-induced lung injury.

M. You, T. Oury, T. Billiar, 2012, American journal of respiratory cell and molecular biology.

Youhua Liu, Ramalinga Kuruba, S. Poloyac, 2009, Journal of Pharmacology and Experimental Therapeutics.