Pu Zhang

发表

Phosphorylation of C/EBPα Inhibits Granulopoiesis

D. Tenen, Wendy S. Wright, O. MacDougald, 2004, Molecular and Cellular Biology.

DNMT1-interacting RNAs block gene specific DNA methylation

Pu Zhang, Loyal A. Goff, Meritxell Alberich-Jorda, 2013, Nature.

Embryonic lethality and impairment of haematopoiesis in mice heterozygous for an AML1-ETO fusion gene

M. Marín‐Padilla, D. Tenen, A. Sharpe, 1997, Nature Genetics.

Octamer Binding Factors and Their Coactivator Can Activate the Murine PU.1 (spi-1) Promoter*

D. Tenen, Dong-er Zhang, H. Radomska, 1996, The Journal of Biological Chemistry.

Anti-tumor NAMPT inhibitor, KPT-9274, mediates gender-dependent murine anemia and nephrotoxicity by regulating SIRT3-mediated SOD deacetylation

J. Byrd, D. Sampath, Pu Zhang, 2021, Journal of Hematology & Oncology.

Targeted BMI1 inhibition impairs tumor growth in lung adenocarcinomas with low CEBPα expression

Kol Jia Yong, D. Neuberg, A. Borczuk, 2016, Science Translational Medicine.

Myeloid lncRNA LOUP Mediates Opposing Regulatory Effects of RUNX1 and RUNX1-ETO in t(8;21) AML

Mahmoud A. Bassal, P. Pandolfi, D. Tenen, 2020, bioRxiv.

Induction of granulocytic differentiation by 2 pathways.

K. Akashi, D. Tenen, A. Friedman, 2002, Blood.

Metabolic Response of Mice to a Postnatal Ablation of CCAAT/Enhancer-binding Protein α*

D. Tenen, Jianqi Yang, Pu Zhang, 2005, Journal of Biological Chemistry.

Upregulation of Interleukin 6 and Granulocyte Colony-Stimulating Factor Receptors by Transcription Factor CCAAT Enhancer Binding Protein a (C/EBP

D. Tenen, A. Iwama, D. Link, 1998 .

Phosphorylation of C/EBPalpha inhibits granulopoiesis.

D. Tenen, Wendy S. Wright, O. MacDougald, 2004, Molecular and cellular biology.

C/EBPbeta is required for 'emergency' granulopoiesis.

K. Akashi, D. Tenen, Tajhal Dayaram, 2006, Nature immunology.

Candida albicans infection

K. Akashi, D. Tenen, Tajhal Dayaram, 2006 .

Neutrophils and Monocytes Express High Levels of PU . l ( Spil ) But Not Spi

David, Gonzalez, D. Tenen, 2000 .

Phosphorylation of C/EBP (cid:2) Inhibits Granulopoiesis

D. Tenen, Wendy S. Wright, O. MacDougald, 2003 .

Loss of Enzyme Activity in Mutated B4GALNT1 Gene Products in Patients with Hereditary Spastic Paraplegia Results in Relatively Mild Neurological Disorders: Similarity with Phenotypes of B4galnt1 Knockout Mice

Kazuro Furukawa, Pu Zhang, K. Furukawa, 2019, Neuroscience.

The chaperone GRP78 is a host auxiliary factor for SARS-CoV-2 and GRP78 depleting antibody blocks viral entry and infection

K. Machida, Amy S. Lee, Pu Zhang, 2021, Journal of Biological Chemistry.

Synergistic effect of BCL2 and FLT3 co-inhibition in acute myeloid leukemia

J. Byrd, J. Blachly, Pu Zhang, 2020, Journal of Hematology & Oncology.

MTA1 promotes the invasion and migration of oral squamous carcinoma by inducing epithelial-mesenchymal transition via the hedgehog signaling pathway.

Pu Zhang, Ying Fu, Baozhong Wang, 2019, Experimental cell research.

cells -mediated induction of granulopoietic development of hematopoietic α The amino terminal and E2F interaction domains are critical for C/EBP

D. Tenen, F. D'Alo', H. Radomska, 2013 .

The amino terminal and E2F interaction domains are critical for C/EBPα-mediated induction of granulopoietic development of hematopoietic cells Running Head: C/EBPα mediated granulopoietic development Scientific Section Heading: Hematopoiesis

D. Tenen, F. D'Alo', H. Radomska, 2003 .

Myeloid Progenitors Granulocytic Development from Bipotential Regulatory Switch Sufficient for Induction of Is a α CCAAT / Enhancer Binding Protein

D. Tenen, D. Scadden, T. Cheng, 1998 .

Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha.

Pu Zhang, Daniel G Tenen, K. Akashi, 2004, Immunity.

Potential Autoregulation of Transcription Factor PU.1 by an Upstream Regulatory Element

Pu Zhang, Gang Huang, Daniel G. Tenen, 2005, Molecular and Cellular Biology.

pDP4, a novel glycoprotein secreted by mature granulocytes, is regulated by transcription factor PU.1.

F. Rosenbauer, K. Wagner, D. Tenen, 2004, Blood.

pDP 4 , a novel glycoprotein secreted by mature granulocytes , is regulated by transcription factor PU

K. Wagner, D. Tenen, A. Iwama, 2004 .

Genomic analysis of cellular hierarchy in acute myeloid leukemia using ultrasensitive LC-FACSeq

C. Bloomfield, J. Byrd, N. Heerema, 2021, Leukemia.

Selective targeting of NAMPT by KPT-9274 in acute myeloid leukemia.

J. Byrd, Pratibha Sharma, E. Baloglu, 2019, Blood advances.

PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis

Y. Okuno, D. Tenen, Tajhal Dayaram, 2008, Nature Genetics.

Distinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1.

Pu Zhang, Bob Löwenberg, Bas J. Wouters, 2007, Blood.

Block of C/EBPα function by phosphorylation in acute myeloid leukemia with FLT3 activating mutations

S. Bohlander, D. Tenen, Tajhal Dayaram, 2006, The Journal of experimental medicine.

The amino terminal and E2F interaction domains are critical for C/EBP alpha-mediated induction of granulopoietic development of hematopoietic cells.

D. Tenen, F. D'Alo', H. Radomska, 2003, Blood.

Dominant-negative mutations of CEBPA, encoding CCAAT/enhancer binding protein-α (C/EBPα), in acute myeloid leukemia

Pu Zhang, Susanne Schnittger, D. Tenen, 2001, Nature Genetics.

CCAAT/Enhancer Binding Protein α Is a Regulatory Switch Sufficient for Induction of Granulocytic Development from Bipotential Myeloid Progenitors

D. Tenen, D. Scadden, H. Radomska, 1998, Molecular and Cellular Biology.

CRISPR/Cas9 Gene-Edited Hematopoietic Stem Cell Therapy for Sickle Cell Disease

Jennifer L. Snead, M. Curran, C. Mickanin, 2017 .

Inducible chronic phase of myeloid leukemia with expansion of hematopoietic stem cells in a transgenic model of BCR-ABL leukemogenesis.

B. Göttgens, J. Kutok, K. Akashi, 2005, Blood.

Reversibility of acute B-cell leukaemia induced by BCR–ABL1

D. Tenen, R. A. Etten, Pu Zhang, 2000, Nature Genetics.

Upregulation of interleukin 6 and granulocyte colony-stimulating factor receptors by transcription factor CCAAT enhancer binding protein alpha (C/EBP alpha) is critical for granulopoiesis.

Pu Zhang, Daniel G. Tenen, Atsushi Iwama, 1998 .

cell in acute promyelocytic leukemia Identification of a myeloid committed progenitor as the cancer-initiating

D. Neuberg, D. Tenen, A. Wagers, 2013 .

Identification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia.

Pu Zhang, Donna Neuberg, Meritxell Alberich-Jorda, 2009, Blood.

Regulation of the PU.1 Gene by Sense and Functional Antisense RNAs Generated through the Same Chromatin Architecture.

F. Rosenbauer, D. Tenen, Tajhal Dayaram, 2006 .

PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2

Pu Zhang, Daniel G Tenen, Etsuro Ito, 2010, Nature Medicine.

The Pu.1 Locus Is Differentially Regulated at the Level of Chromatin Structure and Noncoding Transcription by Alternate Mechanisms at Distinct Developmental Stages of Hematopoiesis

D. Tenen, C. Bonifer, P. Cockerill, 2007, Molecular and Cellular Biology.

Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation.

K. Akashi, H. Iwasaki, D. Tenen, 2005, Blood.

PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element.

F. Rosenbauer, D. Tenen, Tajhal Dayaram, 2008, Genes & development.

Myeloid lncRNA LOUP Mediates Opposing Regulatory Effects of RUNX1 and RUNX1-ETO in t(8;21) AML.

Mahmoud A. Bassal, P. Pandolfi, D. Tenen, 2021, Blood.

LOUP Mediates Opposing Regulatory Effects of RUNX 1 and RUNX 1-ETO in 1 t ( 8 ; 21 ) AML 2

P. Pandolfi, D. Tenen, M. Voso, 2020 .

RUNX1 regulates the CD34 gene in haematopoietic stem cells by mediating interactions with a distal regulatory element

N. Wilson, Y. Okuno, D. Tenen, 2011, The EMBO journal.

Induction of mitochondria-mediated apoptosis and PI3K/Akt/ mTOR-mediated autophagy by aflatoxin B2 in hepatocytes of broilers

Pu Zhang, Zhongxian Xu, Xiaoling Zhao, 2016, Oncotarget.

Transducin b-like protein 1 controls multiple oncogenic networks in diffuse large B-cell lymphoma

J. Byrd, G. Nuovo, K. Young, 2020, Haematologica.

C/EBPa controls acquisition and maintenance of adult hematopoietic stem cell quiescence

D. Tenen, A. Kawasaki, Hong Zhang, 2013, Nature Cell Biology.

ZNF143 protein is an important regulator of the myeloid transcription factor C/EBPα

Pu Zhang, Meritxell Alberich-Jorda, Daniel G. Tenen, 2017, The Journal of Biological Chemistry.

C/EBPβ is required for 'emergency' granulopoiesis

K. Akashi, D. Tenen, Tajhal Dayaram, 2006, Nature Immunology.

Dimeric RFX Proteins Contribute to the Activity and Lineage Specificity of the Interleukin-5 Receptor α Promoter through Activation and Repression Domains

D. Tenen, W. Reith, B. Mach, 1999, Molecular and Cellular Biology.

Targeting DNA Damage Repair Functions of Two Histone Deacetylases, HDAC8 and SIRT6, Sensitizes Acute Myeloid Leukemia to NAMPT Inhibition

J. Byrd, S. Kulp, J. Blachly, 2021, Clinical Cancer Research.

The Runx-PU.1 pathway preserves normal and AML/ETO9a leukemic stem cells.

D. Tenen, P. Staber, Pu Zhang, 2014, Blood.

Sustained PU.1 levels balance cell-cycle regulators to prevent exhaustion of adult hematopoietic stem cells.

Felicia S. L. Ng, S. Orkin, B. Göttgens, 2013, Molecular cell.

Downregulation of c-Jun Expression by Transcription Factor C/EBPα Is Critical for Granulocytic Lineage Commitment

D. Tenen, G. Behre, H. Radomska, 2002, Molecular and Cellular Biology.

Absence of the transcription factor CCAAT enhancer binding protein alpha results in loss of myeloid identity in bcr/abl-induced malignancy.

J. Kutok, F. Rosenbauer, K. Wagner, 2006, Proceedings of the National Academy of Sciences of the United States of America.

PU.1 inhibits GATA-1 function and erythroid differentiation by blocking GATA-1 DNA binding.

S. Orkin, D. Tenen, B. Torbett, 2000, Blood.

Negative cross-talk between hematopoietic regulators: GATA proteins repress PU.1.

D. Tenen, A. Iwama, G. Behre, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Cancer stem cells: targeting tumors at the source.

Pu Zhang, P.-Y. Zhang, Yan Wang, 2015, European review for medical and pharmacological sciences.

Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice.

D. Tenen, Dong-er Zhang, Pu Zhang, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Circ_0010283/miR-377-3p/Cyclin D1 Axis Is Associated With Proliferation, Apoptosis, Migration, and Inflammation of Oxidized Low-density Lipoprotein-Stimulated Vascular Smooth Muscle Cells

Pu Zhang, Weiping Wang, Meilan Li, 2021, Journal of cardiovascular pharmacology.