K. Ong

R. McClelland, M. Shlipak, M. Allison, 2019, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Association of elevated circulating fibroblast growth factor 21 levels with prevalent and incident metabolic syndrome: The Multi-Ethnic Study of Atherosclerosis.

P. Barter, R. McClelland, M. Allison, 2019, Atherosclerosis.

The association of plasma lipids with white blood cell counts: Results from the Multi-Ethnic Study of Atherosclerosis.

R. McClelland, M. Allison, K. Rye, 2019, Journal of clinical lipidology.

The association of plasma lipids with white blood cell counts: Results from the Multi-Ethnic Study of Atherosclerosis

R. McClelland, M. Allison, K. Rye, 2018, bioRxiv.

The relationship of circulating fibroblast growth factor 21 levels with incident atrial fibrillation: The Multi-Ethnic Study of Atherosclerosis.

R. Kronmal, P. Barter, S. Heckbert, 2017, Atherosclerosis.

Relationship of pericardial fat with biomarkers of inflammation and hemostasis, and cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis.

M. Criqui, P. Barter, Jingzhong Ding, 2015, Atherosclerosis.

Research Design and Methods

A. Xu, B. Cheung, K. Ong, 2005, Hormone Research in Paediatrics.

Long-term fenofibrate therapy increases fibroblast growth factor 21 and retinol-binding protein 4 in subjects with type 2 diabetes.

A. Keech, P. Barter, A. Jenkins, 2012, The Journal of clinical endocrinology and metabolism.

Relationship of High‐Density Lipoprotein Cholesterol With Renal Function in Patients Treated With Atorvastatin

P. Barter, D. Waters, D. Demicco, 2018, Journal of the American Heart Association.

Management of obesity in the National Health and Nutrition Examination Survey (NHANES), 2007-2008.

B. Cheung, K. Ong, N. Samaranayake, 2012, Annals of epidemiology.

The relationship of neutrophil elastase and proteinase 3 with risk factors, and chronic complications in type 2 diabetes: A Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) sub-study

V. Gebski, A. Keech, R. Ma, 2021, Diabetes & vascular disease research.

Relationships of adipocyte-fatty acid binding protein and lipocalin 2 with risk factors and chronic complications in type 2 diabetes and effects of fenofibrate: a Fenofibrate Intervention and Event Lowering in Diabetes Sub-study.

A. Keech, A. Jenkins, A. Januszewski, 2020, Diabetes research and clinical practice.

Association of lower total bilirubin level with statin usage: the United States National Health and Nutrition Examination Survey 1999-2008.

P. Barter, K. Rye, B. Cheung, 2011, Atherosclerosis.

The association between lipid levels and leukocyte count: A cross-sectional and longitudinal analysis of three large cohorts

K. Rye, B. Cochran, K. Ong, 2021, American heart journal plus : cardiology research and practice.

Gamma-glutamyl transferase level predicts the development of hypertension in Hong Kong Chinese.

P. Sham, S. Cherny, T. Lam, 2011, Clinica chimica acta; international journal of clinical chemistry.

Cholesteryl Ester Transfer Protein Inhibition Enhances Endothelial Repair and Improves Endothelial Function in the Rabbit

P. Barter, D. Johns, K. Rye, 2015, Arteriosclerosis, thrombosis, and vascular biology.

Apolipoprotein A-I Protects Against Pregnancy-Induced Insulin Resistance in Rats.

P. Barter, K. Rye, K. Ong, 2019, Arteriosclerosis, thrombosis, and vascular biology.

Plasma level of pigment epithelium-derived factor is independently associated with the development of the metabolic syndrome in Chinese men: a 10-year prospective study.

E. Janus, A. Xu, B. Cheung, 2010, The Journal of clinical endocrinology and metabolism.

Role of fibroblast growth factor 21 in gestational diabetes mellitus: A mini‐review

K. Rye, K. Ong, Ben J. Wu, 2018, Clinical endocrinology.

The impact of LDLR function on fibroblast growth factor 21 levels.

K. Rye, K. Ong, G. Hovingh, 2015, Atherosclerosis.

Title Plasma level of adrenomedullin is influenced by a singlenucleotide polymorphism in the adiponectin gene

T. Lam, A. Xu, B. Cheung, 2013 .

Plasma Level of Adrenomedullin Is Influenced by a Single Nucleotide Polymorphism in the Adiponectin Gene

T. Lam, A. Xu, B. Cheung, 2013, PloS one.

Junctional adhesion molecule-1 may have a wider role in cardiovascular disease.

B. Cheung, K. Ong, 2007, Hypertension.

Urotensin II and the Circulatory System

B. Cheung, K. Ong, K. Lam, 2005 .

The Cholesteryl Ester Transfer Protein Inhibitor, des-Fluoro-Anacetrapib, Prevents Vein Bypass-induced Neointimal Hyperplasia in New Zealand White Rabbits

P. Barter, D. Johns, K. Rye, 2019, Scientific Reports.

Fibroblast growth factor 21 in heart failure

K. Rye, K. Ong, B. Tucker, 2022, Heart Failure Reviews.

A single nucleotide polymorphism of interleukin-6 gene is related to plasma adrenomedullin levels Short title : IL 6 SNP and plasma ADM level

T. Lam, B. Cheung, K. Ong, 2014 .

Title A single nucleotide polymorphism of interleukin-6 gene isrelated to plasma adrenomedullin levels

T. Lam, B. Cheung, K. Ong, 2014 .

A single nucleotide polymorphism of interleukin‐6 gene is related to plasma adrenomedullin levels

T. Lam, B. Cheung, K. Ong, 2013, Clinical endocrinology.

Association of Statin Use With Cardiovascular Outcomes by Coronary Calcium: MESA.

M. Nelson, M. Allison, K. Ong, 2019, JACC. Cardiovascular imaging.

High-Density Lipoproteins Inhibit Vascular Endothelial Inflammation by Increasing 3 β -Hydroxysteroid- Δ 24 Reductase Expression and Inducing Heme Oxygenase-1

P. Barter, K. Rye, K. Ong, 2012 .

Utilization of Glucose, Blood Pressure and Lipid Lowering Medications among people with type 2 diabetes in the United States 1999-2010 Short title: Drug utilization of diabetic patients in the US

C. Cheung, B. Cheung, K. Ong, 2014 .

Statin Prescription Patterns and Associations with Subclinical Inflammation

S. Liaw, J. Jonnagaddala, K. Rye, 2022, Medicina.

Relationship of fibroblast growth factor 21 with the prevalence and progression of vascular and valvular calcification: Multi-ethnic study of atherosclerosis.

M. Budoff, M. Allison, K. Rye, 2022, International journal of cardiology.

Using glycosylated haemoglobin to define the metabolic syndrome in adults in the United States

P. Sham, K. Ong, S. Cherny, 2011 .

Prevalence, treatment, and control of diagnosed diabetes in the U.S. National Health and Nutrition Examination Survey 1999-2004.

B. Cheung, K. Ong, K. Lam, 2008, Annals of epidemiology.

Prevalence, Awareness, Treatment, and Control of Hypertension Among United States Adults 1999–2004

C. Lau, B. Cheung, K. Ong, 2007, Hypertension.

High Density Lipoproteins and Diabetes

K. Rye, B. Cochran, K. Ong, 2021, Cells.

Review of the effects of the traditional Chinese medicine Rehmannia Six Formula on diabetes mellitus and its complications

B. Cheung, K. Ong, Terry Yam Chuen Poon, 2011, Journal of diabetes.

Elevated serum alkaline phosphatase and peripheral arterial disease in the United States National Health and Nutrition Examination Survey 1999-2004.

B. Cheung, K. Ong, L. Y. Wong, 2009, International journal of cardiology.

Transcoronary gradients of HDL-associated MicroRNAs in unstable coronary artery disease.

Sebastien A. Choteau, P. Barter, D. Celermajer, 2018, International journal of cardiology.

Circulating microRNAs as Biomarkers of Alzheimer's Disease: A Systematic Review.

P. Sachdev, H. Brodaty, A. Thalamuthu, 2015, Journal of Alzheimer's disease : JAD.

Association of a genetic variant in the apolipoprotein A5 gene with the metabolic syndrome in Chinese

B. Liu, T. Lam, C. Jiang, 2011, Clinical endocrinology.

A single nucleotide polymorphism in APOA5 determines triglyceride levels in Hong Kong and Guangzhou Chinese

T. Lam, B. Liu, C. Jiang, 2010, European Journal of Human Genetics.

Relationship of fibroblast growth factor 21 with subclinical atherosclerosis and cardiovascular events: Multi-Ethnic Study of Atherosclerosis.

M. Szklo, J. Polak, R. McClelland, 2019, Atherosclerosis.

High plasma FGF21 levels predicts major cardiovascular events in patients treated with atorvastatin (from the Treating to New Targets [TNT] Study).

A. Keech, P. Barter, D. Waters, 2019, Metabolism: clinical and experimental.

Baseline Circulating FGF21 Concentrations and Increase after Fenofibrate Treatment Predict More Rapid Glycemic Progression in Type 2 Diabetes: Results from the FIELD Study.

A. Keech, M. Taskinen, P. Barter, 2017, Clinical Chemistry.

Obesity susceptibility genetic variants identified from recent genome-wide association studies: implications in a chinese population.

P. Sham, E. Janus, A. Xu, 2010, The Journal of clinical endocrinology and metabolism.

Association of a polymorphism in the lipin 1 gene with systolic blood pressure in men.

P. Sham, S. Cherny, T. Lam, 2008, American journal of hypertension.

The role of urotensin II in the metabolic syndrome

B. Cheung, K. Ong, L. Y. Wong, 2008, Peptides.

Urotensin II: Its Function in Health and Its Role in Disease

B. Cheung, K. Ong, K. Lam, 2005, Cardiovascular Drugs and Therapy.

Fibroblast growth factor 21 in chronic kidney disease.

K. Rye, K. Ong, Ben J. Wu, 2017, Clinica chimica acta; international journal of clinical chemistry.

Association between plasma alkaline phosphatase and C-reactive protein in Hong Kong Chinese

C. Lau, G. Leung, J. Woo, 2008, Clinical chemistry and laboratory medicine.

The Relationship between Total Bilirubin Levels and Total Mortality in Older Adults: The United States National Health and Nutrition Examination Survey (NHANES) 1999-2004

P. Barter, M. Allison, K. Rye, 2014, PloS one.

High density lipoprotein-associated miRNA is increased following Roux-en-Y gastric bypass surgery for severe obesity.

K. Rye, K. Ong, Yifen Liu, 2021, Journal of lipid research.

APOA1: a Protein with Multiple Therapeutic Functions

K. Rye, B. Cochran, K. Ong, 2021, Current Atherosclerosis Reports.

Altered HDL metabolism in metabolic disorders: insights into the therapeutic potential of HDL.

P. Barter, K. Rye, K. Ong, 2019, Clinical science.

HDL maturation and remodelling.

K. Rye, K. Ong, Shane R Thomas, 2022, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Utilization of glucose, blood pressure, and lipid lowering medications among people with type II diabetes in the United States, 1999-2010.

C. Cheung, B. Cheung, K. Ong, 2014, Annals of epidemiology.

Arthritis: its prevalence, risk factors, and association with cardiovascular diseases in the United States, 1999 to 2008.

P. Barter, K. Rye, B. Cheung, 2013, Annals of epidemiology.

Is Human Cytomegalovirus Infection Associated with Hypertension? The United States National Health and Nutrition Examination Survey 1999–2002

B. Cheung, K. Ong, Chao Li, 2012, PloS one.

Using Glycosylated Hemoglobin to Define the Metabolic Syndrome in United States Adults

P. Sham, S. Cherny, B. Cheung, 2010, Diabetes Care.

Lipoprotein (a) and Coronary Artery Calcification: Prospective study assessing interactions with other risk factors.

R. McClelland, M. Cushman, M. Allison, 2021, Metabolism: clinical and experimental.

Apolipoprotein A‐l improves pancreatic β‐cell function independent of the ATP‐binding cassette transporters ABCA1 and ABCG1

P. Barter, K. Rye, B. Cochran, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Role of Genetic Variants in the Gene Encoding Lipocalin-2 in the Development of Elevated Blood Pressure

P. Sham, S. Cherny, T. Lam, 2011, Clinical and experimental hypertension.

High density lipoprotein‐cholesterol levels increase with age in American women but not in Hong Kong Chinese women

C. Lau, T. Lam, J. Woo, 2009, Clinical endocrinology.

Lipids, lipoprotein distribution and depressive symptoms: the Multi-Ethnic Study of Atherosclerosis

R. McClelland, M. Allison, K. Rye, 2016, Translational Psychiatry.

Utilization of lipid lowering medications among adults in the United States 1999-2006.

H. Tse, B. Cheung, K. Ong, 2010, Atherosclerosis.

Association of omega 3 polyunsaturated fatty acids with incident chronic kidney disease: pooled analysis of 19 cohorts

Toshiko Tanaka, S. Bandinelli, L. Ferrucci, 2023, BMJ.

Relationship of plasma interleukin-6 and its genetic variants with hypertension in Hong Kong Chinese.

P. Sham, S. Cherny, T. Lam, 2011, American journal of hypertension.

Response to Nonpharmacological Treatment of Hypertension: Impact on Prevalence Estimates

B. Cheung, K. Ong, 2007 .

Prevalence, Awareness, Treatment, and Control of Hypertension: United States National Health and Nutrition Examination Survey 2001–2002

C. Lau, B. Cheung, K. Ong, 2006, Journal of clinical hypertension.

Cardiovascular drugs that increase the risk of new-onset diabetes.

P. Barter, K. Ong, D. Waters, 2014, American heart journal.

Association of genetic variants in the adiponectin gene with adiponectin level and hypertension in Hong Kong Chinese.

P. Sham, S. Cherny, T. Lam, 2010, European journal of endocrinology.

Title Association of genetic variants in the adiponectin gene withadiponectin level and hypertension in Hong Kong Chinese

P. Sham, S. Cherny, T. Lam, 2010 .

Association of genetic variants in the adiponectin gene with adiponectin level and hypertension in Hong Kong Chinese Short title: Adiponectin, SNP, and hypertension

P. Sham, S. Cherny, T. Lam, 2010 .

Gender Difference in Blood Pressure Control and Cardiovascular Risk Factors in Americans With Diagnosed Hypertension

B. Cheung, K. Ong, K. Lam, 2008, Hypertension.

Relationship of Lipids and Lipid-Lowering Medications With Cognitive Function: The Multi-Ethnic Study of Atherosclerosis

S. Rapp, J. Luchsinger, A. Fitzpatrick, 2018, American journal of epidemiology.

Relationship of fibroblast growth factor 21 with baseline and new on-study microvascular disease in the Fenofibrate Intervention and Event Lowering in Diabetes study

A. Keech, M. Taskinen, P. Barter, 2015, Diabetologia.

The role of fibroblast growth factor 21 in atherosclerosis.

K. Rye, K. Ong, J. Kokkinos, 2017, Atherosclerosis.

The association of circulating fibroblast growth factor 21 levels with incident heart failure: The Multi-Ethnic Study of Atherosclerosis.

M. Szklo, R. McClelland, M. Allison, 2023, Metabolism: clinical and experimental.

Fibroblast growth factor 21 in heart failure

K. Rye, K. Ong, B. Tucker, 2022, Heart Failure Reviews.

Haplotypes in the urotensin II gene and urotensin II receptor gene are associated with insulin resistance and impaired glucose tolerance

You-Qiang Song, B. Cheung, K. Ong, 2006, Peptides.

The relationship between insulin resistance and vascular calcification in coronary arteries, and the thoracic and abdominal aorta: the Multi-Ethnic Study of Atherosclerosis.

M. Criqui, P. Barter, W. Post, 2014, Atherosclerosis.

Abstract 4025: Prevalence, Awareness, Treatment, and Control of Hypertension in the United States 1999–2004

C. Lau, B. Cheung, K. Ong, 2006 .

The association of serum lipid and lipoprotein levels with total and differential leukocyte counts: Results of a cross-sectional and longitudinal analysis of the UK Biobank.

K. Rye, B. Cochran, K. Ong, 2020, Atherosclerosis.

FGF21 in NAFLD.

K. Rye, K. Ong, Huating Li, 2019, Metabolism: clinical and experimental.

Plasma adrenomedullin level is related to a single nucleotide polymorphism in the adrenomedullin gene.

P. Sham, S. Cherny, T. Lam, 2011, European journal of endocrinology.

The relationship of fibroblast growth factor 21 with cardiovascular outcome events in the Fenofibrate Intervention and Event Lowering in Diabetes study

A. Keech, M. Taskinen, P. Barter, 2015, Diabetologia.

A genetic variant in the gene encoding adrenomedullin predicts the development of dysglycemia over 6.4 years in Chinese.

P. Sham, S. Cherny, T. Lam, 2011, Clinica chimica acta; international journal of clinical chemistry.

Adiponectin gene variants and the risk of coronary heart disease: a 16-year longitudinal study.

P. Sham, H. Tse, E. Janus, 2014, European journal of endocrinology.

Increasing HDL levels by inhibiting cholesteryl ester transfer protein activity in rabbits with hindlimb ischemia is associated with increased angiogenesis.

P. Barter, D. Johns, K. Rye, 2015, International journal of cardiology.

Relationship of pericardial fat with lipoprotein distribution: The Multi-Ethnic study of atherosclerosis.

M. Criqui, P. Barter, Jingzhong Ding, 2015, Atherosclerosis.

High-Density Lipoprotein-Associated miR-223 Is Altered after Diet-Induced Weight Loss in Overweight and Obese Males

Sebastien A. Choteau, P. Clifton, P. Barter, 2016, PloS one.

Using machine learning to predict cardiovascular risk using self-reported questionnaires: Findings from the 45 and up study.

J. Jonnagaddala, K. Rye, K. Ong, 2023, International journal of cardiology.

Association of hypertension with single nucleotide polymorphisms in the quantitative trait locus for abdominal obesity-metabolic syndrome on chromosome 17

C. Lau, Y. Man, B. Cheung, 2006, Journal of Human Hypertension.

Treatment and control of diabetes mellitus in the United States National Health and Nutrition Examination Survey, 1999-2002.

B. Cheung, K. Ong, K. Lam, 2006, Journal of the cardiometabolic syndrome.

Arthritis: its prevalence, risk factors, and association with cardiovascular diseases in the United States National Health and Nutrition Examination Survey 1999-2008

P. Barter, K. Rye, B. Cheung, 2011 .

Title Haplotypes in the urotensin II gene and urotensin II receptor gene are associated with insulin resistance and impaired glucose tolerance

You-Qiang Song, B. Cheung, K. Ong, 2008 .

Fibroblast growth factor 21 in cardio-metabolic disorders: a systematic review and meta-analysis.

S. Wong, Tong Liu, G. Tse, 2018, Metabolism: clinical and experimental.

Plasma concentration of pigment epithelium‐derived factor is closely associated with blood pressure and predicts incident hypertension in Chinese: a 10‐year prospective study

E. Janus, A. Xu, B. Cheung, 2012, Clinical endocrinology.

The Association of Serum Lipid and Lipoprotein Levels with Total and Differential Leukocyte Counts: Results of a Cross-sectional and Longitudinal Analysis of the UK Biobank

K. Rye, B. Cochran, K. Ong, 2020, medRxiv.

ApoA-I Protects Pancreatic β-cells from Cholesterol-induced Mitochondrial Damage and Restores their Ability to Secrete Insulin

M. Wilkins, N. Deshpande, R. Whan, 2023, bioRxiv.

Usefulness of Certain Protein Biomarkers for Prediction of Coronary Heart Disease.

K. Rye, L. Jonasson, K. Ong, 2019, The American journal of cardiology.

Omega-3 Fatty Acid Biomarkers and Incident Atrial Fibrillation.

W. Guan, D. Mozaffarian, E. Rimm, 2023, Journal of the American College of Cardiology.

Lipoprotein (a) and the risk of elevated depressive symptoms: The Multi-Ethnic Study of Atherosclerosis.

M. Allison, K. Rye, K. Ong, 2020, Journal of psychiatric research.

Insulin lispro: a potential role in preventing nocturnal hypoglycaemia in young children with diabetes mellitusInsulin lispro and nocturnal hypoglycaemia in child diabetics M. E. FordAdams etal.Original article

J. Edge, C. Acerini, K. Ong, 2003 .

Evaluation of the combined use of adiponectin and C-reactive protein levels as biomarkers for predicting the deterioration in glycaemia after a median of 5.4 years

B. Cheung, T. Lam, A. Xu, 2011, Diabetologia.

High density lipoprotein-associated miRNA is increased following Roux-en-Y gastric bypass surgery for severe obesity

K. Rye, K. Ong, Yifen Liu, 2020, Journal of lipid research.

Urotensin II: Its Function in Health and Its Role in Disease

B. Cheung, K. Ong, K. Lam, 2005, Cardiovascular drugs and therapy.

Insulin lispro: a potential role in preventing nocturnal hypoglycaemia in young children with diabetes mellitus

N. Murphy, M. Ford-Adams, J. Edge, 2003, Diabetic medicine : a journal of the British Diabetic Association.

Association of F11 receptor gene polymorphisms with central obesity and blood pressure

S. Cherny, T. Lam, P. Sham, 2008, Journal of internal medicine.

A genetic variant in the gene encoding fibrinogen beta chain predicted development of hypertension in Chinese men

P. Sham, S. Cherny, T. Lam, 2010, Thrombosis and Haemostasis.

Polymorphisms of the Fibrinogen-Beta Gene are Related to 2-Hour Glucose Level after Oral Glucose Tolerance Test in Hong Kong Chinese

T. Lam, B. Cheung, K. Ong, 2008, Disease markers.

C-reactive protein as a predictor of hypertension in the Hong Kong Cardiovascular Risk Factor Prevalence Study (CRISPS) cohort

S. Cherny, T. Lam, P. Sham, 2012, Journal of Human Hypertension.

Plasma levels of fibrinogen and C-reactive protein are related to interleukin-6 gene −572C>G polymorphism in subjects with and without hypertension

B. Cheung, K. Ong, R. Leung, 2007, Journal of Human Hypertension.

3 Relationship of plasma interleukin-6 and its genetic variants with hypertension in Hong 4

K. Ong, S. Cherny, R. Leung, 2011 .