K. Kusakabe

发表

Coal gasification in CO2 atmosphere and its kinetics since 1948: A brief review

Muhammad Usman, M. Irfan, K. Kusakabe, 2011 .

Conversion of methane with carbon dioxide into C2 hydrocarbons over metal oxides

Y. Nishiyama, K. Kusakabe, K. Asami, 1995 .

Synthesis of ethane and ethylene from methane and carbon dioxide over praseodymium oxide catalysts

K. Kusakabe, K. Asami, Y. Ohtsuka, 1997 .

Discovery of imidazo[1,2-b]pyridazine derivatives: selective and orally available Mps1 (TTK) kinase inhibitors exhibiting remarkable antiproliferative activity.

Yusuke Nakamura, H. Yoshida, K. Kusakabe, 2015, Journal of medicinal chemistry.

A unique hinge binder of extremely selective aminopyridine-based Mps1 (TTK) kinase inhibitors with cellular activity.

Yusuke Nakamura, K. Kusakabe, Y. Daigo, 2015, Bioorganic & medicinal chemistry.

The Timing of GM-CSF Expression Plasmid Administration Influences the Th1/Th2 Response Induced by an HIV-1-Specific DNA Vaccine1

Y. Miyagi, K. Okuda, I. Aoki, 2000, The Journal of Immunology.

Response Induced by an HIV-1-Specific DNA Administration Influences the Th 1 / Th 2 The Timing of GM-CSF Expression Plasmid Klinman and

Y. Miyagi, K. Okuda, I. Aoki, 2000 .

JNJ-67569762, A 2-Aminotetrahydropyridine-Based Selective BACE1 Inhibitor Targeting the S3 Pocket: From Discovery to Clinical Candidate.

D. Moechars, K. Kusakabe, L. Leclercq, 2021, Journal of medicinal chemistry.

Shear resonance measurement on structuring of liquids confined between mica surfaces

M. Mizukami, K. Kusakabe, K. Kurihara, 2004 .

HIV‐1‐specific cell‐mediated immune responses induced by DNA vaccination were enhanced by mannan‐coated liposomes and inhibited by anti‐interferon‐γ antibody

K. Okuda, K. Kusakabe, N. Ishii, 1997, Immunology.

Human immunodeficiency virus type‐1‐specific immune responses induced by DNA vaccination are greatly enhanced by mannan‐coated diC14‐amidine

K. Okuda, J. Ruysschaert, F. Hirahara, 1997, European journal of immunology.

Selective CB2 agonists with anti-pruritic activity: discovery of potent and orally available bicyclic 2-pyridones.

H. Hamana, K. Kawamoto, K. Yasui, 2013, Bioorganic & medicinal chemistry.

A SWITCH OF ENANTIOFACIAL SELECTIVITIES USING DESIGNED SIMILAR CHIRAL LIGANDS IN ZIRCONIUM-CATALYZED ASYMMETRIC AZA DIELS-ALDER REACTIONS

K. Kusakabe, H. Ishitani, S. Kobayashi, 1999 .

Facile Construction of an Amino-1,3-Oxazine Scaffold using Burgess Reagent Under Mild Conditions

K. Kusakabe, S. Yoshida, M. Masui, 2020 .

Structure-Based Design of Selective β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors: Targeting the Flap to Gain Selectivity over BACE2.

D. Moechars, K. Kusakabe, N. Asada, 2019, Journal of medicinal chemistry.

Diaminopyridine-based potent and selective mps1 kinase inhibitors binding to an unusual flipped-Peptide conformation.

Yusuke Nakamura, Takayuki Kanazawa, Kazuo Ueda, 2012, ACS medicinal chemistry letters.

Indazole-based potent and cell-active Mps1 kinase inhibitors: rational design from pan-kinase inhibitor anthrapyrazolone (SP600125).

Yusuke Nakamura, K. Kusakabe, Y. Daigo, 2013, Journal of medicinal chemistry.

Small-molecule BACE1 inhibitors: a patent literature review (2011 to 2020)

K. Kusakabe, Chien‐Chi Hsiao, Frederik J. R. Rombouts, 2020, Expert opinion on therapeutic patents.

Design, synthesis, and binding mode prediction of 2-pyridone-based selective CB2 receptor agonists.

Yukio Tada, Hideyuki Takenaka, Keiko Kawamoto, 2013, Bioorganic & medicinal chemistry.

Trifluoromethyl Dihydrothiazine‐Based β‐Secretase (BACE1) Inhibitors with Robust Central β‐Amyloid Reduction and Minimal Covalent Binding Burden

K. Kusakabe, Shinji Suzuki, Y. Kido, 2019, ChemMedChem.

Formation of ethane and ethylene by the reaction of methane and carbon dioxide over unsupported metal oxides

K. Kusakabe, Kenji Asami, Yasuo Ohtsuka, 1997 .

Discovery of Atabecestat (JNJ-54861911): A Thiazine-Based β-Amyloid Precursor Protein Cleaving Enzyme 1 Inhibitor Advanced to the Phase 2b/3 EARLY Clinical Trial.

L. Tritsmans, K. Kusakabe, M. Timmers, 2021, Journal of medicinal chemistry.

Molecular Dynamics Simulation of Friction of Hydrocarbon Thin Films

A. Chatterjee, Momoji Kubo, Akira Miyamoto, 1999 .

Structure-Based Approaches to Improving Selectivity through Utilizing Explicit Water Molecules: Discovery of Selective β-Secretase (BACE1) Inhibitors over BACE2.

D. Moechars, K. Kusakabe, Shinji Suzuki, 2021, Journal of medicinal chemistry.

Synthesis of a 6-CF3-Substituted 2-Amino-dihydro-1,3-thiazine β-Secretase Inhibitor by N, N-Diethylaminosulfur Trifluoride-Mediated Chemoselective Cyclization.

K. Kusakabe, Shinji Suzuki, T. Oguma, 2018, The Journal of organic chemistry.

Thickness dependence of absorption of molecular thin films studied using FECO spectroscopy

K. Kusakabe, K. Kurihara, T. Haraszti, 2001 .

Balancing potency and basicity by incorporating fluoropyridine moieties: Discovery of a 1-amino-3,4-dihydro-2,6-naphthyridine BACE1 inhibitor that affords robust and sustained central Aβ reduction.

K. Kusakabe, Y. Kido, Shiho Yamamoto, 2021, European journal of medicinal chemistry.

Discovery of Extremely Selective Fused Pyridine-Derived β-Site Amyloid Precursor Protein-Cleaving Enzyme (BACE1) Inhibitors with High In Vivo Efficacy through 10s Loop Interactions.

D. Moechars, K. Kusakabe, Frederik J. R. Rombouts, 2021, Journal of medicinal chemistry.

Discovery of an Extremely Potent Thiazine-Based β-Secretase (BACE1) Inhibitor with Reduced Cardiovascular and Liver Toxicity at a Low Projected Human Dose.

K. Kusakabe, Shinji Suzuki, N. Asada, 2019, Journal of medicinal chemistry.

Origin of the kinetic HDAC2‐selectivity of an HDAC inhibitor

Yukihiro Itoh, Takayoshi Suzuki, K. Kusakabe, 2023, J. Comput. Chem..

Discovery of Potent and Centrally Active 6-Substituted 5-Fluoro-1,3-dihydro-oxazine β-Secretase (BACE1) Inhibitors via Active Conformation Stabilization.

Kenji Nakahara, Takahiko Yamamoto, K. Kusakabe, 2018, Journal of medicinal chemistry.

Rational Design of Novel 1,3-Oxazine Based β-Secretase (BACE1) Inhibitors: Incorporation of a Double Bond To Reduce P-gp Efflux Leading to Robust Aβ Reduction in the Brain.

K. Kusakabe, Y. Kido, T. Fukushima, 2018, Journal of medicinal chemistry.