J. Shearer

发表

An Air- and Water-Tolerant Zinc Hydride Cluster That Reacts Selectively With CO2.

David M. Ermert, I. Ghiviriga, V. Catalano, 2015, Angewandte Chemie.

Adiabaticity of the proton-coupled electron-transfer step in the reduction of superoxide effected by nickel-containing superoxide dismutase metallopeptide-based mimics.

J. Shearer, J. Schmitt, Heather S Clewett, 2015, The journal of physical chemistry. B.

Influence of sequential guanidinium methylation on the energetics of the guanidinium...guanine dimer and guanidinium...guanine...cytosine trimer: implications for the control of protein...DNA interactions by arginine methyltransferases.

J. Shearer, 2008, The journal of physical chemistry. B.

Transformation of a mononitrosyl iron complex to a [2Fe-2S] cluster by a cysteine analogue.

J. Shearer, I. Ivanović‐Burmazović, J. MacDonald, 2014, Journal of the American Chemical Society.

A [3Fe-3S](3+) cluster with exclusively μ-sulfide donors.

K. Abboud, J. Shearer, Leslie J. Murray, 2016, Chemical communications.

Bisamidate and mixed amine/amidate NiN2S2 complexes as models for nickel-containing acetyl coenzyme A synthase and superoxide dismutase: an experimental and computational study.

E. Hegg, J. Shearer, R. Staples, 2010, Inorganic chemistry.

A chloride ion contained in a cobalt 'claw': [Co3(DADIT)3]Cl(PF6)2.

W. Kaminsky, J. Shearer, J. Kovacs, 2003, Acta crystallographica. Section C, Crystal structure communications.

The first example of a nitrile hydratase model complex that reversibly binds nitriles.

W. Kaminsky, J. Shearer, D. Rittenberg, 2002, Journal of the American Chemical Society.

Access to Metal Centers and Fluxional Hydride Coordination Integral for CO2 Insertion into [Fe3(μ-H)3]3+ Clusters.

R. Ferreira, V. Catalano, J. Shearer, 2021, Inorganic chemistry.

Structure and Unprecedented Reactivity of a Mononuclear Nonheme Cobalt(III)-Iodosylbenzene Complex.

S. Fukuzumi, J. Shearer, Yong‐Min Lee, 2020, Angewandte Chemie.

A mononuclear nonheme cobalt(iii)-hydroperoxide complex with an amphoteric reactivity in electrophilic and nucleophilic oxidative reactions.

J. Shearer, Yong‐Min Lee, Kyung‐Bin Cho, 2016, Dalton transactions.

Characterization and dioxygen reactivity of a new series of coordinatively unsaturated thiolate-ligated manganese(II) complexes.

W. Kaminsky, J. Shearer, M. Coggins, 2012, Inorganic chemistry.

Thioester synthesis by a designed nickel enzyme models prebiotic energy conversion

J. Shearer, H. Shafaat, A. C. Manesis, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Periodic trends within a series of five-coordinate thiolate-ligated [MII(SMe2N4(tren))]+ (M = Mn, Fe, Co, Ni, Cu, Zn) complexes, including a rare example of a stable CuII-thiolate.

W. Kaminsky, J. Shearer, S. Shoner, 2007, Inorganic chemistry.

Properties of square-pyramidal alkyl-thiolate Fe(III) complexes, including an analogue of the unmodified form of nitrile hydratase.

Roslyn M. Theisen, W. Kaminsky, J. Shearer, 2008, Inorganic chemistry.

Synthetic models for the cysteinate-ligated non-heme iron enzyme superoxide reductase: observation and structural characterization by XAS of an Fe(III)-OOH intermediate.

J. Shearer, J. Kovacs, R. Scarrow, 2002, Journal of the American Chemical Society.

Steric and electronic control over the reactivity of a thiolate-ligated Fe(II) complex with dioxygen and superoxide: reversible mu-oxo dimer formation.

Roslyn M. Theisen, W. Kaminsky, J. Shearer, 2004, Inorganic chemistry.

Reactivity of a biomimetic W(iv) bis-dithiolene complex with CO2 leading to formate production and structural rearrangement.

J. Shearer, P. Williard, Eunsuk Kim, 2019, Dalton transactions.

Scaffold-based [Fe]-hydrogenase model: H2 activation initiates Fe(0)-hydride extrusion and non-biomimetic hydride transfer

Eileen R. Sullivan, Michael J. Rose, V. Lynch, 2021, Chemical science.

pH Dependent Reversible Formation of a Binuclear Ni2 Metal-Center within a Peptide Scaffold

J. Shearer, Brenna C Keegan, D. Ocampo, 2019, Inorganics.

Cysteinate protonation and water hydrogen bonding at the active-site of a nickel superoxide dismutase metallopeptide-based mimic: implications for the mechanism of superoxide reduction.

J. Shearer, J. Schmitt, K. Neupane, 2014, Journal of the American Chemical Society.

Ni K-edge XAS suggests that coordination of Ni(II) to the unstructured amyloidogenic region of the human prion protein produces a Ni(2) bis-mu-hydroxo dimer.

J. Shearer, P. Soh, 2007, Journal of inorganic biochemistry.

Tuning copper-dioxygen reactivity and exogenous substrate oxidations via alterations in ligand electronics.

K. Karlin, Hong Liang, J. Shearer, 2003, Journal of the American Chemical Society.

Bonding and the role of electrostatics in driving C-C bond formation in high valent organocopper compounds.

J. Shearer, K. Lancaster, Dovydas Vasiliauskas, 2022, Chemical communications.

Luminescent copper(I) halide butterfly dimers coordinated to [Au(CH3imCH2py)2]BF4 and [Au(CH3imCH2quin)2]BF4.

V. Catalano, J. Shearer, Jineun Kim, 2009, Inorganic chemistry.

Alkylation of Nucleic Acids by a Model Quinone Methide

S. Rokita, J. Shearer, Jianhong Yang, 1999 .

Substrate oxidation by copper-dioxygen adducts: mechanistic considerations.

K. Karlin, L. Zakharov, J. Shearer, 2005, Journal of the American Chemical Society.

A Biochemical Nickel(I) State Supports Nucleophilic Alkyl Addition: A Roadmap for Methyl Reactivity in Acetyl Coenzyme A Synthase

N. Lehnert, J. Shearer, H. Shafaat, 2019, Inorganic chemistry.

Interactions of Metal-Based and Ligand-Based Electronic Spins in Neutral Tripyrrindione π Dimers.

J. Shearer, A. Astashkin, E. Tomat, 2017, Inorganic chemistry.

Tripyrrindione as a Redox-Active Ligand: Palladium(II) Coordination in Three Redox States.

J. Shearer, A. Astashkin, E. Tomat, 2015, Angewandte Chemie.

Influence of sequential thiolate oxidation on a nitrile hydratase mimic probed by multiedge X-ray absorption spectroscopy.

J. Shearer, César A. Masitas, C. Grapperhaus, 2012, Inorganic chemistry.

Modeling the geometric, electronic, and redox properties of iron(III)-containing amphiphiles with asymmetric [NN'O] headgroups.

J. Shearer, E. Rentschler, C. Verani, 2011, Inorganic chemistry.

The Hexahistidine Motif of Host-Defense Protein Human Calprotectin Contributes to Zinc Withholding and Its Functional Versatility.

Elizabeth M. Nolan, J. Shearer, Toshiki G. Nakashige, 2016, Journal of the American Chemical Society.

Sequential oxidations of thiolates and the cobalt metallocenter in a synthetic metallopeptide: implications for the biosynthesis of nitrile hydratase.

Souvik Roy, Arnab Dutta, J. Shearer, 2013, Inorganic chemistry.

Sequence proximity between Cu(II) and Cu(I) binding sites of human copper transporter 1 model peptides defines reactivity with ascorbate and O2.

Kathryn L Haas, J. Shearer, Bruno Aliès, 2016, Journal of inorganic biochemistry.

Copper: Hemocyanin/Tyrosinase Models

K. Karlin, J. Shearer, 2014 .

A nickel phosphine complex as a fast and efficient hydrogen production catalyst.

T. Groy, V. Mujica, J. Shearer, 2015, Journal of the American Chemical Society.

Preparation and properties of [NiII(BEES)(Cl)](BPh4): a NiII complex in a mixed nitrogen/thioether coordination environment

J. Shearer, D. L. Jacobs, J. Lai, 2002 .

Manganese complexes of 1,3,5-triaza-7-phosphaadamantane (PTA): the first nitrogen-bound transition-metal complex of PTA.

J. Shearer, B. Frost, Rongcai Huang, 2006, Inorganic chemistry.

How Do Oxidized Thiolate Ligands Affect the Electronic and Reactivity Properties of a Nitrile Hydratase Model Compound

J. Shearer, D. Schweitzer, J. Kovacs, 2000 .

Synthesis, characterization, and crystal structure of a quadruply bonded dimolybdenum(II) complex containing the water-soluble phosphine 1,3,5-triaza-7-phosphaadamantane (PTA)

J. Shearer, B. Frost, S. B. Miller, 2006 .

Diamine preparation for synthesis of a water soluble Ni(II) salen complex.

S. Rokita, J. Shearer, 1999, Bioorganic & medicinal chemistry letters.

Distinguishing rate-limiting electron versus H-atom transfers in Cu2O2-mediated oxidative N-dealkylations: application of inter- versus intramolecular kinetic isotope effects.

K. Karlin, J. Shearer, C. X. Zhang, 2003, Journal of the American Chemical Society.

Use of a metallopeptide-based mimic provides evidence for a proton-coupled electron-transfer mechanism for superoxide reduction by nickel-containing superoxide dismutase.

J. Shearer, 2013, Angewandte Chemie.

The amyloid-beta peptide of Alzheimer's disease binds Cu(I) in a linear bis-his coordination environment: insight into a possible neuroprotective mechanism for the amyloid-beta peptide.

J. Shearer, V. Szalai, 2008, Journal of the American Chemical Society.

The copper(II) adduct of the unstructured region of the amyloidogenic fragment derived from the human prion protein is redox-active at physiological pH.

J. Shearer, P. Soh, 2007, Inorganic chemistry.

Crystallographic and computational studies of luminescent, binuclear gold(I) complexes, Au(I)2(Ph2P(CH2)nPPh2)2I2 (n = 3-6).

J. Fettinger, Jianhua Jia, J. Shearer, 2013, Inorganic chemistry.

Subtle Modulation of Cu4X4L2 Phosphine Cluster Cores Leads to Changes in Luminescence.

V. Catalano, J. Shearer, Kelly Chen, 2015, Inorganic chemistry.

Modulation of luminescence by subtle anion-cation and anion-π interactions in a trigonal Au(I)···Cu(I) complex.

C. Strasser, V. Catalano, J. Shearer, 2012, Inorganic chemistry.

Formation and structure of two luminescent salts of [Au(SCSN3)2]- obtained through the [2 + 3] cyclization of carbon disulfide and azide ion.

J. Shearer, J. Schmitt, A. Balch, 2014, Dalton transactions.

Isolation of a (dinitrogen)tricopper(I) complex.

K. Abboud, J. Shearer, Leslie J. Murray, 2014, Journal of the American Chemical Society.

The novel hydrogen-rich binuclear cobalt complex anion, [(CoH3)2H3](5-).

J. Shearer, D. E. Linn, Jerod M. Kieser, 2014, Dalton transactions.

Chalcogen Impact on Covalency within Molecular [Cu3(μ3-E)]3+ Clusters (E = O, S, Se): A Synthetic, Spectroscopic, and Computational Study.

R. Ferreira, V. Catalano, J. Shearer, 2018, Inorganic chemistry.

Synthesis and reactivity of a mononuclear non-haem cobalt(IV)-oxo complex

Bin Wang, M. Baik, J. Shearer, 2017, Nature Communications.

The Oxo-Wall Remains Intact: A Tetrahedrally Distorted Co(IV)-Oxo Complex.

N. Lehnert, J. Shearer, Yong‐Min Lee, 2021, Journal of the American Chemical Society.

Heme/Cu/O2 reactivity: change in FeIII-(O2 2-)-CuII unit peroxo binding geometry effected by tridentate copper chelation.

K. Karlin, J. Shearer, A. Zuberbühler, 2004, Journal of the American Chemical Society.

Novel alkoxide cluster topologies featuring rare seesaw geometry at transition metal centers.

G. Cisneros, J. Shearer, Philip D. Martin, 2013, Chemistry.

Model Peptide Studies Reveal a Mixed Histidine-Methionine Cu(I) Binding Site at the N-Terminus of Human Copper Transporter 1.

Kathryn L Haas, J. Shearer, M. J. Pushie, 2015, Inorganic chemistry.

Copper ligation to soluble oligomers of the English mutant of the amyloid-β peptide yields a linear Cu(I) site that is resistant to O2 oxidation.

J. Shearer, J. Schmitt, Heather S Clewett, 2013, Chemical communications.

Both Met(109) and Met(112) are utilized for Cu(II) coordination by the amyloidogenic fragment of the human prion protein at physiological pH.

J. Shearer, P. Soh, S. Lentz, 2008, Journal of inorganic biochemistry.

A Redox-Active, Compact Molecule for Cross-Linking Amyloidogenic Peptides into Nontoxic, Off-Pathway Aggregates: In Vitro and In Vivo Efficacy and Molecular Mechanisms.

Jeffrey S Derrick, Edward J Merino, B. Ruotolo, 2015, Journal of the American Chemical Society.

Insight into the structure and mechanism of nickel-containing superoxide dismutase derived from peptide-based mimics.

J. Shearer, Jason Shearer, 2014, Accounts of chemical research.

Use of metallopeptide based mimics demonstrates that the metalloprotein nitrile hydratase requires two oxidized cysteinates for catalytic activity.

J. Shearer, Paige E Callan, J. Amie, 2010, Inorganic Chemistry.

Metallopeptide based mimics with substituted histidines approximate a key hydrogen bonding network in the metalloenzyme nickel superoxide dismutase.

J. Shearer, K. Neupane, Paige E Callan, 2009, Inorganic Chemistry.

Dioxygen and superoxide stability of metallopeptide based mimics of nickel containing superoxide dismutase: the influence of amine/amidate vs. bis-amidate ligation.

J. Shearer, 2013, Journal of inorganic biochemistry.

Preparation and Characterization of a Formally NiIV-Oxo Complex with a Triplet Ground State and Application in Oxidation Reactions.

N. Lehnert, J. Shearer, Yong‐Min Lee, 2022, Journal of the American Chemical Society.

Dioxygen mediated conversion of {Fe(NO)2}9 dinitrosyl iron complexes to Roussin's red esters.

J. Shearer, J. Fitzpatrick, H. Kalyvas, 2013, Chemical communications.

Phenol nitration induced by an {Fe(NO)2}(10) dinitrosyl iron complex.

J. Shearer, L. Kirschenbaum, H. Kalyvas, 2011, Journal of the American Chemical Society.

Cu K-edge X-ray absorption spectroscopy reveals differential copper coordination within amyloid-β oligomers compared to amyloid-β monomers.

J. Shearer, V. Szalai, Thao T Tran, 2010, Chemical communications.

Controlled Protonation of [2Fe-2S] Leading to MitoNEET Analogues and Concurrent Cluster Modification.

J. Shearer, Kady Oakley, Eunsuk Kim, 2021, Inorganic chemistry.

Dinitrogen Insertion and Cleavage by a Metal-Metal Bonded Tricobalt(I) Cluster.

V. Catalano, J. Shearer, Leslie J. Murray, 2021, Journal of the American Chemical Society.

How does cyanide inhibit superoxide reductase? Insight from synthetic FeIIIN4S model complexes

W. Kaminsky, J. Shearer, J. Benedict, 2003, Proceedings of the National Academy of Sciences of the United States of America.

A modular approach to redox-active multimetallic hydrophobes of discoid topology.

M. Rodgers, J. Shearer, R. Shanmugam, 2010, Inorganic Chemistry.

Enhancing reactivity via structural distortion.

R. Loloee, J. Shearer, S. Shoner, 2002, Inorganic chemistry.

One octarepeate expansion to the human prion protein alters both the Zn2+ and Cu2+ coordination environments within the octarepeate domain.

J. Shearer, Chi L. L. Pham, Kyle E Rosenkoetter, 2011, Inorganic Chemistry.

A nickel superoxide dismutase maquette that reproduces the spectroscopic and functional properties of the metalloenzyme.

J. Shearer, Li Long, 2006, Inorganic chemistry.

Modeling the reactivity of superoxide reducing metalloenzymes with a nitrogen and sulfur coordinated iron complex.

W. Kaminsky, J. Shearer, S. Lovell, 2001, Inorganic chemistry.

Why is there an "inert" metal center in the active site of nitrile hydratase? Reactivity and ligand dissociation from a five-coordinate Co(III) nitrile hydratase model.

W. Kaminsky, J. Shearer, S. Lovell, 2001, Journal of the American Chemical Society.

A Co(III) complex in a mixed sulfur/nitrogen ligand environment: modeling the substrate- and product-bound forms of the metalloenzyme thiocyanate hydrolase.

J. Shearer, S. Lovell, J. Kovacs, 2000, Inorganic chemistry.

Copper ligation to soluble oligomers of the English mutant of the amyloid-β peptide yields a linear Cu(I) site that is resistant to O2 oxidation.

J. Shearer, Heather S Clewett, K. L. Peck, 2013, Chemical communications.

Scrutinizing formally NiIV centers through the lenses of core spectroscopy, molecular orbital theory, and valence bond theory

D. Nordlund, J. Shearer, C. Titus, 2023, Chemical science.