Quan Du

发表

Enhanced gene delivery and siRNA silencing by gold nanoparticles coated with charge-reversal polyelectrolyte.

Qiao Jiang, Shutao Guo, Xing-Jie Liang, 2010, ACS nano.

Peptides containing blocks of different charge densities facilitate cell uptake of oligonucleotides.

D. Liang, Quan Du, Hao Wen, 2015, Physical chemistry chemical physics : PCCP.

An efficient and high-throughput electroporation microchip applicable for siRNA delivery.

Wei Wang, Zewen Wei, Deyao Zhao, 2011, Lab on a chip.

RNA-seq identified a super-long intergenic transcript functioning in adipogenesis

Zicai Liang, Quan Du, Xiaoxia Wang, 2013, RNA biology.

A laminar flow electroporation system for efficient DNA and siRNA delivery.

Wei Wang, Zewen Wei, Deyao Zhao, 2011, Analytical chemistry.

Focusing on RISC assembly in mammalian cells.

E. Sonnhammer, A. Chalk, C. Wahlestedt, 2008, Biochemical and biophysical research communications.

A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites

C. Wahlestedt, Zicai Liang, Quan Du, 2005, Nucleic Acids Research.

tRNA modification profiles of the fast-proliferating cancer cells.

S. Zhai, Zhenjun Yang, Quan Du, 2016, Biochemical and biophysical research communications.

Binary and ternary complexes based on polycaprolactone-graft-poly (N, N-dimethylaminoethyl methacrylate) for targeted siRNA delivery.

Zicai Liang, Jinfeng Xing, Liandong Deng, 2012, Biomaterials.

High-throughput screening using siRNA (RNAi) libraries

Zicai Liang, Quan Du, Xiaoxia Wang, 2007, Expert review of molecular diagnostics.

Vector-based siRNA delivery strategies for high-throughput screening of novel target genes

C. Wahlestedt, Zicai Liang, Quan Du, 2005, Journal of RNAi and gene silencing : an international journal of RNA and gene targeting research.

A universal plasmid library encoding all permutations of small interfering RNA.

Bo Wang, C. Wahlestedt, Zicai Liang, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Therapeutic potentials of gene silencing by RNA interference: principles, challenges, and new strategies.

Kwong Wai Choy, Quan Du, K. Choy, 2014, Gene.

Single modification at position 14 of siRNA strand abolishes its gene‐silencing activity by decreasing both RISC loading and target degradation

K. Ye, Zicai Liang, Quan Du, 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Effects of chain length and hydrophobicity/charge ratio of AMP on its antimicrobial activity

D. Liang, Quan Du, Yuqiong Xia, 2017, Science China Chemistry.

Structural contributions of blocked or grafted poly(2-dimethylaminoethyl methacrylate) on PEGylated polycaprolactone nanoparticles in siRNA delivery.

Zicai Liang, Jinfeng Xing, Liandong Deng, 2011, Biomaterials.

The effect of guanidinylation of PEGylated poly(2-aminoethyl methacrylate) on the systemic delivery of siRNA.

Xing-jie Liang, Zicai Liang, Yuanyu Huang, 2013, Biomaterials.

Rainbowarray Microsphere-Based Gene Detection Assay

Quan Du, Fan Yi, Ying Xu, 2020, SLAS technology.

Elimination pathways of systemically delivered siRNA.

Zicai Liang, Shutao Guo, Yuanyu Huang, 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

The decreased N6-methyladenine DNA modification in cancer cells.

Hong Wang, Zhenjun Yang, Wei Song, 2016, Biochemical and biophysical research communications.

Knockdown of slincRAD leads to defective adipose development in vivo.

Quan Du, Jinghao Liu, Huicheng Bai, 2019, Biochemical and biophysical research communications.

Site-Specific RNase A Activity Was Dramatically Reduced in Serum from Multiple Types of Cancer Patients

Mei Zhao, Zicai Liang, Quan Du, 2014, PloS one.

Analysis of LncRNA expression in cell differentiation

Quan Du, Dong Li, Xianfeng Ding, 2018, RNA biology.

Ternary complexes of amphiphilic polycaprolactone-graft-poly (N,N-dimethylaminoethyl methacrylate), DNA and polyglutamic acid-graft-poly(ethylene glycol) for gene delivery.

Xing-jie Liang, Zicai Liang, Jinfeng Xing, 2011, Biomaterials.

Amphiphilic and biodegradable methoxy polyethylene glycol-block-(polycaprolactone-graft-poly(2-(dimethylamino)ethyl methacrylate)) as an effective gene carrier.

Paul C. Wang, Anil Kumar, Xu Zhang, 2011, Biomaterials.

Relationship between peptide structure and antimicrobial activity as studied by de novo designed peptides.

D. Liang, Quan Du, Dong Li, 2014, Biochimica et biophysica acta.

MALAT‐1 interacts with hnRNP C in cell cycle regulation

Zicai Liang, Quan Du, Feng Yang, 2013, FEBS letters.

Modification of the siRNA Passenger Strand by 5‐Nitroindole Dramatically Reduces its Off‐Target Effects

Zicai Liang, Quan Du, Jie Zheng, 2012, Chembiochem : a European journal of chemical biology.

DNA immobilization : Silanized nucleic acids and nanoprinting

H. Swerdlow, O. Larsson, Zicai Liang, 2005 .

siRNA Has Greatly Elevated Mismatch Tolerance at 3′-UTR Sites

Zicai Liang, Quan Du, Huang Huang, 2012, PloS one.

Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice.

Ling Peng, David D Smith, John J Rossi, 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

Circulating microRNA-122 as a potential biomarker for liver injury.

Zhiyuan Hu, Zicai Liang, Quan Du, 2012, Molecular medicine reports.

siRNA: The Specificity and off‐Target Effects

Zicai Liang, Quan Du, Huang Huang, 2011 .

Profiling of mismatch discrimination in RNAi enabled rational design of allele-specific siRNAs

T. Zhang, Zicai Liang, Zhenjun Yang, 2009, Nucleic acids research.

Characterization of a carcinogenesis-associated long non-coding RNA

Z. Ling, Zicai Liang, Quan Du, 2012, RNA biology.

Specificity profiling of CRISPR system reveals greatly enhanced off-target gene editing

Quan Du, T. Tang, Jing Wei, 2020, Scientific Reports.

Exogenous nucleic acids aggregate in non-P-body cytoplasmic granules when transfected into cultured cells

Wenjun Xie, Heping Cheng, Zicai Liang, 2010, Frontiers in Biology.

A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites

Claes Wahlestedt, Quan Du, C. Wahlestedt, 2005, Nucleic acids research.

Effective small interfering RNAs and phosphorothioate antisense DNAs have different preferences for target sites in the luciferase mRNAs.

Claes Wahlestedt, Ola Larsson, Quan Du, 2003, Biochemical and biophysical research communications.

Caged circular siRNAs for photomodulation of gene expression in cells and mice† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc03842a

Quan Du, Dong Li, Fan Yi, 2017, Chemical science.

Comprehensive analysis of sequence‐specific stability of siRNA

Zicai Liang, Yuanyu Huang, Quan Du, 2010 .

Comprehensive analysis of sequence-specific stability of siRNA.

Zicai Liang, Yuanyu Huang, Quan Du, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

siRNAs as potential drugs.

Feng Yan, Xiaoxia Wang, Quan Du, 2010, Drug discovery today. Technologies.

Validating siRNA using a reporter made from synthetic DNA oligonucleotides.

C. Wahlestedt, Zicai Liang, Quan Du, 2004, Biochemical and biophysical research communications.

Analysis of siRNA specificity on targets with double-nucleotide mismatches

Maria Grahn, Claes Wahlestedt, Quan Du, 2008, Nucleic acids research.

An estrogen receptor α suppressor, microRNA‐22, is downregulated in estrogen receptor α‐positive human breast cancer cell lines and clinical samples

Chen Wu, D. Lin, Dianke Yu, 2010, The FEBS journal.

Z. Ling, Zicai Liang, Quan Du, 2012 .

Long non-coding RNA slincRAD functions in methylation regulation during the early stage of mouse adipogenesis

Quan Du, Fan Yi, Zhengxi Zhang, 2019, RNA biology.

Profiling single-guide RNA specificity reveals a mismatch sensitive core sequence

Quan Du, Quan Du, Fan Yi, 2017, Scientific Reports.

Systemic and tumor-targeted delivery of siRNA by cyclic NGR and isoDGR motif-containing peptides.

Xing-jie Liang, Zicai Liang, Shutao Guo, 2016, Biomaterials science.

Systemic Administration of siRNA via cRGD-containing Peptide

Xing-jie Liang, Zicai Liang, Shutao Guo, 2015, Scientific Reports.

Inter-molecular β-sheet structure facilitates lung-targeting siRNA delivery

Zicai Liang, Lihe Zhang, D. Liang, 2016, Scientific Reports.

MicroRNA Profiling in Chinese Patients with Primary Sjögren Syndrome Reveals Elevated miRNA-181a in Peripheral Blood Mononuclear Cells

Quan Du, Fan Yi, Fengchun Zhang, 2014, The Journal of Rheumatology.

Autoantigen-targeting microRNAs in Sjögren’s syndrome

Li Wang, Quan Du, Fan Yi, 2016, Clinical Rheumatology.

Synthesis and biological evaluation of peptide-siRNA conjugates with phosphodiester unit as linker

Zhenjun Yang, Lihe Zhang, Quan Du, 2013, Science China Chemistry.

RNA Interference with chemically modified siRNA.

Claes Wahlestedt, Quan Du, C. Wahlestedt, 2006, Current topics in medicinal chemistry.

Tumor-suppressive microRNA-22 inhibits the transcription of E-box-containing c-Myc target genes by silencing c-Myc binding protein

Zicai Liang, J. Xiong, Quan Du, 2010, Oncogene.