Jianping Lin

发表

Biomimetic DNA Nanotubes: Nanoscale Channel Design and Applications.

C. Fan, Pi Liu, Lihua Wang, 2019, Angewandte Chemie.

Study of the mechanism of protonated histidine-induced conformational changes in the Zika virus dimeric envelope protein using accelerated molecular dynamic simulations.

Yang Li, Jianping Lin, Y. Li, 2017, Journal of molecular graphics & modelling.

Complex silica composite nanomaterials templated with DNA origami

Hao Yan, Chunhai Fan, Dongyuan Zhao, 2018, Nature.

Biosensor-based monitoring of the central metabolic pathway metabolites.

Jianping Lin, D. Ding, Jinlong Li, 2020, Biosensors & bioelectronics.

Multistage virtual screening and identification of novel HIV-1 protease inhibitors by integrating SVM, shape, pharmacophore and docking methods.

Jianping Lin, Jinlong Li, Yu Wei, 2015, European journal of medicinal chemistry.

Engineering catechol 1, 2-dioxygenase by design for improving the performance of the cis, cis-muconic acid synthetic pathway in Escherichia coli

Jianping Lin, Yanhe Ma, Yuanyuan Zhang, 2015, Scientific Reports.

Identification of a Different Agonist-Binding Site and Activation Mechanism of the Human P2Y1 Receptor

Pi Liu, Jianping Lin, Dongmei Li, 2017, Scientific Reports.

Simultaneous engineering of an enzyme's entrance tunnel and active site: the case of monoamine oxidase MAO-N† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6sc05381e

M. Reetz, Pi Liu, Peiyuan Yao, 2017, Chemical science.

The effect of dimerization on the activation and conformational dynamics of adenosine A1 receptor.

N. Gao, Jianping Lin, Dongmei Li, 2019, Physical chemistry chemical physics : PCCP.

Discovery of Novel Hepatitis C Virus NS5B Polymerase Inhibitors by Combining Random Forest, Multiple e-Pharmacophore Modeling and Docking

Jianping Lin, Jie Qing, Ming Wu, 2016, PloS one.

Targeting HIV/HCV Coinfection Using a Machine Learning-Based Multiple Quantitative Structure-Activity Relationships (Multiple QSAR) Method

Wei Li, Jianping Lin, Yu Wei, 2019, International journal of molecular sciences.

Targeting against HIV/HCV Co-infection using Machine Learning-based multitarget-quantitative structure-activity relationships (mt-QSAR) Methods

Jianping Lin, Yu Wei, Zhangyong Hong, 2019, bioRxiv.

A fluorescent tool set for yeast Atg proteins

Wei Liu, Zhiping Xie, Jianping Lin, 2015, Autophagy.

Identification of new potent A1 adenosine receptor antagonists using a multistage virtual screening approach.

Jianping Lin, Dongmei Li, Yu Wei, 2019, European journal of medicinal chemistry.

Molecular mechanism of SCARB2-mediated attachment and uncoating of EV71

Yuna Sun, Z. Rao, Xiangxi Wang, 2014, Protein & Cell.

Curcumin suppresses proliferation and induces apoptosis of human hepatocellular carcinoma cells via the wnt signaling pathway.

T. Guo, Lifang Li, Lirong Zhang, 2013, International journal of oncology.

Binding of a Dy(III) complex to apoferritin inhibits iron mineralization

Jianping Lin, Dongmei Li, Lei Z. Zhang, 2015 .

The mechanisms of pei-yuan-tong-nao capsule as a therapeutic agent against cerebrovascular disease

Ping Wang, Jianping Lin, Yu Wei, 2020 .

Structure-based QSAR, molecule design and bioassays of protease-activated receptor 1 inhibitors

Pi Liu, Jianping Lin, Dongmei Li, 2017, Journal of biomolecular structure & dynamics.

Design and synthesis of O-GlcNAcase inhibitors via 'click chemistry' and biological evaluations.

Wei Zhao, Jianping Lin, Lei Li, 2011, Carbohydrate research.

Synthesis of Triazole‐Epothilones by Using Cu2O Nanoparticles to Catalyze 1,3‐Dipolar Cycloaddition

Jianping Lin, Quan Zhang, Yue-hua Chen, 2012 .

Studying the adsorption of DNA nanostructures on graphene in the aqueous phase using molecular dynamic simulations.

Jianping Lin, Jixue Sun, Yang Li, 2017, Journal of molecular graphics & modelling.

Engineered LPMO Significantly Boosting Cellulase-Catalyzed Depolymerization of Cellulose.

Pi Liu, M. Jiang, Jianping Lin, 2020, Journal of agricultural and food chemistry.

Identification of novel PAD4 inhibitors based on a pharmacophore model derived from transition state coordinates.

R. Liu, Jianping Lin, Dongmei Li, 2017, Journal of molecular graphics & modelling.

Hub genes associated with immune cell infiltration in breast cancer, identified through bioinformatic analyses of multiple datasets

Jianping Lin, Luyuan Li, Xicheng Liu, 2022, Cancer biology & medicine.

Effect of dihydromyricetin on SARS-CoV-2 viral replication and pulmonary inflammation and fibrosis

Honggang Zhou, Jianping Lin, Dongmei Li, 2021, Phytomedicine.

Myricetin ameliorates bleomycin-induced pulmonary fibrosis in mice by inhibiting TGF-β signaling via targeting HSP90β.

Hailong Li, Honggang Zhou, Jianping Lin, 2020, Biochemical pharmacology.

The full activation mechanism of the adenosine A1 receptor revealed by GaMD and Su-GaMD simulations

Jianping Lin, Jixue Sun, Dongmei Li, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Engineering a d-lactate dehydrogenase that can super-efficiently utilize NADPH and NADH as cofactors

Yin Li, Hengkai Meng, Pi Liu, 2016, Scientific Reports.

Capturing transient antibody conformations with DNA origami epitopes

T. Ando, C. Fan, Pi Liu, 2020, Nature Communications.

Both Baicalein and Gallocatechin Gallate Effectively Inhibit SARS-CoV-2 Replication by Targeting Mpro and Sepsis in Mice

Honggang Zhou, Jianping Lin, Dongmei Li, 2021, Inflammation.

Structure-activity relationships in a series of C2-substituted gluco-configured tetrahydroimidazopyridines as β-glucosidase inhibitors.

Wei Zhao, Jianping Lin, Wenpeng Zhang, 2011, Bioorganic & medicinal chemistry.

Analyzing the genetic characteristics of a tryptophan-overproducing Escherichia coli

Hongwu Ma, Pi Liu, Jianping Lin, 2020, Bioprocess and Biosystems Engineering.

Going Beyond the Local Catalytic Activity Space of Chitinase Using a Simulation-Based Iterative Saturation Mutagenesis Strategy

Hongwu Ma, Pi Liu, Jianping Lin, 2022, ACS Catalysis.

Approach to thiazole-containing tetrahydropyridines via Aza–Rauhut–Currier reaction and their potent fungicidal and insecticidal activity

Guo Xiaofeng, Jianping Lin, Yu Wei, 2016 .

Biocatalytic Route to Chiral 2-Substituted-1,2,3,4-Tetrahydroquinolines Using Cyclohexylamine Oxidase Muteins

Jie Ren, Peiyuan Yao, Qiaqing Wu, 2018 .

Epothilone D and its 9-Methyl analogues: combinatorial syntheses, conformation, and biological activities.

Bin Zhang, Jianping Lin, Jiadai Zhai, 2013, European journal of medicinal chemistry.

DNA Framework-Encoded Mineralization of Calcium Phosphate

Sichun Yang, C. Fan, Pi Liu, 2020, Chem.

Myricetin Inhibits SARS-CoV-2 Viral Replication by Targeting Mpro and Ameliorates Pulmonary Inflammation

Honggang Zhou, Jianping Lin, Dongmei Li, 2021, Frontiers in Pharmacology.

Phytochemicals with NO inhibitory effects and interactions with iNOS protein from Trigonostemon howii.

Jing Xu, Jun Ma, Dongho Lee, 2017, Bioorganic chemistry.

Identification of a small molecule that simultaneously suppresses virulence and antibiotic resistance of Pseudomonas aeruginosa

Jianping Lin, Shouguang Jin, Jinlong Li, 2016, Scientific Reports.

Inverting the enantiopreference of nitrilase-catalyzed desymmetric hydrolysis of prochiral dinitriles by reshaping the binding pocket with a "mirror-image" strategy.

Peiyuan Yao, Yunfeng Cui, Qiaqing Wu, 2020, Angewandte Chemie.

Constructing a synthetic pathway for acetyl-coenzyme A from one-carbon through enzyme design

Hongwu Ma, Yan Nie, Qian Wang, 2019, Nature Communications.

Improving chemical similarity ensemble approach in target prediction

Zheng Yin, Zhonghua Wang, Jianping Lin, 2016, Journal of Cheminformatics.

Molecular architecture of the acetohydroxyacid synthase holoenzyme.

Jianping Lin, Jixue Sun, Z. Xi, 2020, The Biochemical journal.

Discovery and extensive in vitro evaluations of NK-HDAC-1: a chiral histone deacetylase inhibitor as a promising lead.

Guoxian Gu, Jianping Lin, Zheng Yin, 2012, Journal of medicinal chemistry.

Biomimetic semisynthesis of arglabin from parthenolide.

Jianping Lin, Jing Long, Jiadai Zhai, 2012, The Journal of organic chemistry.

Guaianolide sesquiterpene lactones, a source to discover agents that selectively inhibit acute myelogenous leukemia stem and progenitor cells.

Bin Han, Yahui Ding, Xiaoyan Ma, 2012, Journal of medicinal chemistry.

Elastase Inhibitor Cyclotheonellazole A: Total Synthesis and In Vivo Biological Evaluation for Acute Lung Injury

Honglei Xu, Jianping Lin, Mengyi Zhang, 2022, Journal of medicinal chemistry.

The Mechanism by which 146-N-Glycan Affects the Active Site of Neuraminidase

Pi Liu, Jianping Lin, Dongmei Li, 2015, PloS one.

An insight into antagonist binding and induced conformational dynamics of class B GPCR corticotropin-releasing factor receptor 1.

Jianping Lin, Dongmei Li, Jianping Lin, 2015, Molecular bioSystems.

Crystal Structure of the Core Region of Hantavirus Nucleocapsid Protein Reveals the Mechanism for Ribonucleoprotein Complex Formation

X. Wang, Yuna Sun, Pi Liu, 2015, Journal of Virology.

Discovery of novel dual adenosine A1/A2A receptor antagonists using deep learning, pharmacophore modeling and molecular docking

Jianping Lin, Mukuo Wang, Shujing Hou, 2021, PLoS Comput. Biol..

A hybrid CO2 electroreduction system mediated by enzyme-cofactor conjugates coupled with Cu nanoparticle-catalyzed cofactor regeneration

C. You, Pi Liu, Jianping Lin, 2019 .

Elucidating direct kinase targets of compound Danshen dropping pills employing archived data and prediction models

Jia Sun, Chunlai Zhao, Hairong Wang, 2020, Scientific Reports.

Prediction of host - pathogen protein interactions between Mycobacterium tuberculosis and Homo sapiens using sequence motifs

W. Liu, Z. Rao, Jianping Lin, 2015, BMC Bioinformatics.

Efficient O-Glycosylation of Triterpenes Enabled by Protein Engineering of Plant Glycosyltransferase UGT74AC1

Pi Liu, Jianping Lin, Yanhe Ma, 2020, ACS Catalysis.

Structure of Mycobacterium tuberculosis cytochrome bcc in complex with Q203 and TB47, two anti-TB drug candidates

L. Guddat, T. Ran, Z. Rao, 2021, eLife.

Identification of Novel Antagonists Targeting Cannabinoid Receptor 2 Using a Multi-Step Virtual Screening Strategy

Jianping Lin, Dongmei Li, Mukuo Wang, 2021, Molecules.

High-Efficiency Secretion and Directed Evolution of Chitinase BcChiA1 in Bacillus subtilis for the Conversion of Chitinaceous Wastes Into Chitooligosaccharides

Gang Fu, Jianping Lin, Jinlong Li, 2020, Frontiers in Bioengineering and Biotechnology.

Catalytic mechanism of cytochrome P450 for N-methylhydroxylation of nicotine: reaction pathways and regioselectivity of the enzymatic nicotine oxidation.

C. Zhan, Jianping Lin, Xiaoqin Huang, 2013, Dalton transactions.

Exploring skyline for both MSE‐based label‐free proteomics and HRMS quantitation of small molecules

Shanshan Liu, Xin Chen, Jinhua Xu, 2014, Proteomics.

Constructing a synthetic pathway for acetyl-coenzyme A from one-carbon through enzyme design

Hongwu Ma, Chaoguang Tian, Yin Li, 2019, Nature Communications.

YaTCM: Yet another Traditional Chinese Medicine Database for Drug Discovery

Chunfeng Ma, Xiaoyong Zhao, Jianping Lin, 2018, Computational and structural biotechnology journal.

Programming DNA origami patterning with non-canonical DNA-based metallization reactions

J. Chao, K. Gothelf, C. Fan, 2019, Nature Communications.

Discovery of novel CDK2 inhibitors using multistage virtual screening and in vitro melanoma cell lines

Jianping Lin, Mukuo Wang, Lihong Yang, 2023, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Directed Evolution and Rational Design of Mechanosensitive Channel MscCG2 for Improved Glutamate Excretion Efficiency.

Jie Shen, Ping Zheng, Jibin Sun, 2021, Journal of agricultural and food chemistry.

Totally atom-economical synthesis of lactic acid from formaldehyde: combined bio-carboligation and chemo-rearrangement without the isolation of intermediates

Yanhe Ma, Pi Liu, Jianping Lin, 2020 .

Saturated fatty acids increase LPI to reduce FUNDC1 dimerization and stability and mitochondrial function

Quan Chen, G. Shui, Yushan Zhu, 2023, EMBO reports.

Weighted Co-Expression Network Analysis Identifies RNF181 as a Causal Gene of Coronary Artery Disease

Jihong Han, Jianping Lin, Ke Feng, 2022, Frontiers in Genetics.

Capturing transient antibody conformations with DNA origami epitopes

T. Ando, C. Fan, Pi Liu, 2020, Nature Communications.

Significance of cuproptosis‐related lncRNA signature in LUAD prognosis and immunotherapy: A machine learning approach

Lihong Yang, Jianping Lin, L. Liang, 2023, Thoracic cancer.

Bioactivity-explorer: a web application for interactive visualization and exploration of bioactivity data

Zhonghua Wang, Chunfeng Ma, Lu Liang, 2019, Journal of Cheminformatics.

Crystal Structures of the C-Glycosyltransferase UGT708C1 from Buckwheat Provide Insights into the Mechanism of C-Glycosylation

Jianping Lin, Xiaoqiang Wang, Yuequan Shen, 2020, Plant Cell.

GCDB: a glaucomatous chemogenomics database for in silico drug discovery

Yu Wei, Jianping Lin, Chunfeng Ma, 2018, Database J. Biol. Databases Curation.

The cryo-EM structure of HAV bound to a neutralizing antibody-F4

Z. Rao, Pi Liu, Xiangxi Wang, 2019 .

Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors

Z. Rao, Pi Liu, Xiangxi Wang, 2019, PLoS biology.

Creation of a Prognostic Model Using Cuproptosis-Associated Long Noncoding RNAs in Hepatocellular Carcinoma

Yueyue Fu, Lihong Yang, Jianping Lin, 2023, International journal of molecular sciences.

Computer-aided design of short peptide ligands targeting tumor necrosis factor-alpha for adsorbent applications.

Wenzhong Li, Jianping Lin, N. Ma, 2018, Journal of materials chemistry. B.

PvrA is a novel regulator that contributes to Pseudomonas aeruginosa pathogenesis by controlling bacterial utilization of long chain fatty acids

Jianping Lin, Shouguang Jin, Yu Wei, 2020, Nucleic acids research.

Identification of a Different Agonist-Binding Site and Activation Mechanism of the Human P2Y1 Receptor

Pi Liu, Jianping Lin, Dongmei Li, 2017, Scientific Reports.

Large-scale comparison of machine learning algorithms for target prediction of natural products

Qi Wu, Jianping Lin, L. Liang, 2022, Briefings Bioinform..

A Ligand-observed Mass Spectrometry Approach Integrated into the Fragment Based Lead Discovery Pipeline

Xin Chen, Shuai Chen, Quan Wang, 2015, Scientific Reports.

Activation and conformational dynamics of a class B G-protein-coupled glucagon receptor.

Jianping Lin, Jixue Sun, Dongmei Li, 2016, Physical chemistry chemical physics : PCCP.

DRDB: A Machine Learning Platform to Predict Chemical-Protein Interactions towards Diabetic Retinopathy

Jianping Lin, Shanshan Li, Yu Wei, 2022, Oxidative medicine and cellular longevity.

Charge Neutralization Drives the Shape Reconfiguration of DNA Nanotubes.

Sichun Yang, C. Fan, Pi Liu, 2018, Angewandte Chemie.

Theoretical study of the mechanism of protein arginine deiminase 4 (PAD4) inhibition by F-amidine.

Jianping Lin, Dongmei Li, Cui Liu, 2015, Journal of molecular graphics & modelling.

Interpretable-ADMET: a web service for ADMET prediction and optimization based on deep neural representation

Jianping Lin, Shanshan Li, Yu Wei, 2022, Bioinform..

PRMT5 promotes ovarian cancer growth through enhancing Warburg effect by methylating ENO1

Chunze Zhang, Yuan Zhang, Tao Wang, 2023, MedComm.

Simultaneous engineering of an enzyme's entrance tunnel and active site: the case of monoamine oxidase MAO-N† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6sc05381e

M. Reetz, Pi Liu, Peiyuan Yao, 2017, Chemical science.

Guaianolide sesquiterpene lactones, a source to discover agents that selectively inhibit acute myelogenous leukemia stem and progenitor cells.

B. Han, Jianping Lin, Dongmei Li, 2012, Journal of medicinal chemistry.

Verbenalin alleviates acute lung injury induced by sepsis and IgG immune complex through GPR18 receptor.

Jianping Lin, Dongmei Li, Ximo Wang, 2023, Cellular signalling.