D. Adams

D. Adams, A. Butler, A R Butler, 1999, Fortschritte der Chemie organischer Naturstoffe = Progress in the chemistry of organic natural products. Progres dans la chimie des substances organiques naturelles.

PDE4 cAMP phosphodiesterases: modular enzymes that orchestrate signalling cross-talk, desensitization and compartmentalization.

M. Houslay, D. Adams, David R Adams, 2003, The Biochemical journal.

The Development of a Marine Natural Product-based Antifouling Paint

Liming Yan, Matz Berggren, J. Burgess, 2003, Biofouling.

The synthesis of 8,10,12-triazaprostaglandin analogues: 1,2,4-triazolidine-3,5-dione derivatives

D. Adams, A. Barnes, M. Thompson, 1984 .

RACK1, A multifaceted scaffolding protein: Structure and function

P. Kiely, D. Adams, P. A. Kiely, 2011, Cell Communication and Signaling.

RACK 1 , A multifaceted scaffolding protein : Structure and function

P. Kiely, D. Adams, D. Ron, 2011 .

Topographical Mapping of Isoform-Selectivity Determinants for J-Channel-Binding Inhibitors of Sphingosine Kinases 1 and 2.

S. Pyne, N. Pyne, D. Adams, 2019, Journal of medicinal chemistry.

1,3-Dipolar cycloaddition approach to the construction of new bis-heterocycles from thymine as potential non-nucleoside reverse transcriptase inhibitors

C. Monneret, D. Adams, D. Grierson, 1997 .

Preparation and anti-HIV activity of N-3-substituted thymidine nucleoside analogs.

C. Monneret, J. Florent, D. Adams, 1997, Journal of medicinal chemistry.

Sphingosine 1-phosphate and sphingosine kinases in health and disease: Recent advances.

S. Pyne, N. Pyne, D. Adams, 2016, Progress in lipid research.

Identification and characterization of small-molecule ligands that maintain pluripotency of human embryonic stem cells.

Graeme Milligan, Andrew H Baker, Joanne C Mountford, 2010, Biochemical Society transactions.

N- versus O-Alkylation of 2,3'-anhydrothymidine: reaction of the obtained pyrimidinium salts with azide ion

D. Adams, D. Grierson, A. Chiaroni, 1993 .

The mechanism for the rearrangement of the adamantly cation

C. Ridyard, D. Adams, P. Bailey, 1996 .

Erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA) blocks differentiation and maintains the expression of pluripotency markers in human embryonic stem cells.

G. Milligan, G. Baillie, M. Houslay, 2010, The Biochemical journal.

Unexpected N‐Demethylation of Oxymorphone and Oxycodone N‐Oxides Mediated by the Burgess Reagent: Direct Synthesis of Naltrexone, Naloxone, and Other Antagonists from Oxymorphone

T. Hudlický, D. Adams, Aleš Machara, 2012 .

Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, beta-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5.

G. Baillie, M. Houslay, Xiang Li, 2006, The Biochemical journal.

Biofilm-Specific Cross-Species Induction of Antimicrobial Compounds in Bacilli

J. Burgess, D. Adams, Liming Yan, 2003, Applied and Environmental Microbiology.

Serine Phosphorylation of the Insulin-like Growth Factor I (IGF-1) Receptor C-terminal Tail Restrains Kinase Activity and Cell Growth*

R. O'Connor, P. Kiely, D. Buckley, 2012, The Journal of Biological Chemistry.

Dimerization of cAMP phosphodiesterase-4 (PDE4) in living cells requires interfaces located in both the UCR1 and catalytic unit domains

G. Baillie, A. Dunlop, M. Houslay, 2015, Cellular signalling.

p62 (SQSTM1) and cyclic AMP phosphodiesterase-4A4 (PDE4A4) locate to a novel, reversible protein aggregate with links to autophagy and proteasome degradation pathways.

G. Baillie, M. Houslay, F. Christian, 2010, Cellular signalling.

1H NMR structural and functional characterisation of a cAMP-specific phosphodiesterase-4D5 (PDE4D5) N-terminal region peptide that disrupts PDE4D5 interaction with the signalling scaffold proteins, beta-arrestin and RACK1.

G. Baillie, A. Dunlop, M. Houslay, 2007, Cellular signalling.

Expression, intracellular distribution and basis for lack of catalytic activity of the PDE4A7 isoform encoded by the human PDE4A cAMP-specific phosphodiesterase gene.

G. Baillie, M. Houslay, D. Adams, 2004, The Biochemical journal.

Occupancy of the catalytic site of the PDE4A4 cyclic AMP phosphodiesterase by rolipram triggers the dynamic redistribution of this specific isoform in living cells through a cyclic AMP independent process.

G. Baillie, M. Houslay, R. Terry, 2003, Cellular signalling.

High-content screening of feeder-free human embryonic stem cells to identify pro-survival small molecules.

G. Milligan, M. Houslay, P. D. Andrews, 2010, The Biochemical journal.

A scanning peptide array approach uncovers association sites within the JNK/βarrestin signalling complex

G. Baillie, A. Dunlop, M. Houslay, 2009, FEBS letters.

Concise routes to pyrazolo[1,5-a]pyridin-3-yl pyridazin-3-ones.

D. Adams, G. Rosair, Robert W. Allcock, 2008, Organic & biomolecular chemistry.

Elucidation of a structural basis for the inhibitor-driven, p62 (SQSTM1)-dependent intracellular redistribution of cAMP phosphodiesterase-4A4 (PDE4A4).

G. Baillie, M. Houslay, F. Christian, 2011, Journal of medicinal chemistry.

Concise Routes to Pyrazolo[1,5-a]pyridin-3-yl Pyridazin-3-ones

D. Adams, G. Rosair, Robert W. Allcock, 2008 .

A new model for regulation of sphingosine kinase 1 translocation to the plasma membrane in breast cancer cells

S. Pyne, N. Pyne, F. Torta, 2021, The Journal of biological chemistry.

Antagonists of the human adenosine A2A receptor. Part 1: Discovery and synthesis of thieno[3,2-d]pyrimidine-4-methanone derivatives.

A. Lawrence, R. Gillespie, S. Ward, 2008, Bioorganic & medicinal chemistry letters.

The sphingosine 1-phosphate receptor 2 is shed in exosomes from breast cancer cells and is N-terminally processed to a short constitutively active form that promotes extracellular signal regulated kinase activation and DNA synthesis in fibroblasts

S. Pyne, N. Pyne, D. Adams, 2018, Oncotarget.

Convergent synthesis of 2,3-bisarylpyrazolones through cyclization of bisacylated pyrazolidines and hydrazines

T. Hudlický, D. Adams, A. Gołębiowski, 2006 .

The Potential of a Novel Class of EPAC-Selective Agonists to Combat Cardiovascular Inflammation

D. Adams, S. Yarwood, G. Barker, 2017, Journal of cardiovascular development and disease.

Direct Interaction between Scaffolding Proteins RACK1 and 14-3-3ζ Regulates Brain-derived Neurotrophic Factor (BDNF) Transcription*

R. O'Connor, P. Kiely, D. Adams, 2011, The Journal of Biological Chemistry.

Impact of liquid lipid on development and stability of trimyristin nanostructured lipid carriers for oral delivery of resveratrol

D. Adams, K. Singh, C. Houacine, 2020 .

Two Diketopiperazines and One Halogenated Phenol from Cultures of the Marine Bacterium, Pseudoalteromonas luteoviolacea

P. Wright, J. Burgess, D. Adams, 2000 .

RACK(1) to the future – a historical perspective

G. Baillie, R. O'Connor, P. Kiely, 2013, Cell Communication and Signaling.

2-Aryl-3,3,3-trifluoro-2-hydroxypropionic acids: a new class of protein tyrosine phosphatase 1B inhibitors.

Blair F. Johnston, S. Mackenzie, D. Adams, 2007, Bioorganic & medicinal chemistry letters.

Putting the lid on phosphodiesterase 4

M. Houslay, D. Adams, 2010, Nature Biotechnology.

Extracellular Loop 2 of the Free Fatty Acid Receptor 2 Mediates Allosterism of a Phenylacetamide Ago-Allosteric Modulator

Leigh A. Stoddart, B. Hudson, G. Milligan, 2011, Molecular Pharmacology.

Indoline derivatives as 5-HT(2C) receptor agonists.

G. Kennett, C. Dourish, D. Adams, 2004, Bioorganic & medicinal chemistry letters.

Chemically engineering ligand selectivity at the free fatty acid receptor 2 based on pharmacological variation between species orthologs

B. Hudson, G. Milligan, E. Kostenis, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Elucidation of a structural basis for the inhibitor-driven, p62 (SQSTM1)-dependent intracellular redistribution of cAMP phosphodiesterase-4A4 (PDE4A4).

G. Baillie, M. Houslay, F. Christian, 2011, Journal of medicinal chemistry.

Sphingosine Kinase 2 in Autoimmune/Inflammatory Disease and the Development of Sphingosine Kinase 2 Inhibitors.

S. Pyne, N. Pyne, D. Adams, 2017, Trends in pharmacological sciences.

Extracellular Loop 2 Of The Free Fatty Acid Receptor 2 Mediates Allosterism Of A Phenylacetamide Ago-Allosteric Modulator

Leigh A. Stoddart, B. Hudson, E. Kostenis, 2011 .

Sphingosine 1-phosphate and sphingosine kinases in health and disease: Recent advances.

S. Pyne, N. Pyne, D. Adams, 2016, Progress in lipid research.

Serine Phosphorylation of the Insulin-like Growth Factor I (IGF-1) Receptor C-terminal Tail Restrains Kinase Activity and Cell Growth*

P. Kiely, D. Buckley, D. Adams, 2012, The Journal of Biological Chemistry.

Phosphorylation of RACK 1 on Tyrosine 52 by c-Abl Is Required for Insulin-like Growth Factor I-mediated Regulation of Focal Adhesion Kinase *

G. Baillie, M. Houslay, P. Kiely, 2009 .

Erythro-9-(2-hydroxy-3-nonyl)adenine (EHNA) blocks differentiation and maintains the expression of pluripotency markers in human embryonic stem cells.

G. Milligan, G. Baillie, M. Houslay, 2010, The Biochemical journal.