C. Lazure

N. Seidah, M. Cantin, M. Chrétien, 1986, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Synthetic proregion-related peptides of proprotein convertases, PC1 and furin, represent potent inhibitors of each protease

N. Seidah, A. Basak, C. Lazure, 2002 .

Affinity purification of proteinases by a combination of immobilized peptidyl aldehyde and semicarbazone.

N. Seidah, M. Chrétien, A. Basak, 1992, Journal of chromatography.

Novel purification method for mammalian seminal plasma phospholipid‐binding proteins reveals the presence of a novel member of this family of protein in stallion seminal fluid

C. Lazure, M. Ménard, D. Vaillancourt, 2003, Molecular reproduction and development.

Type II domains of BSP-A1/-A2 proteins: binding properties, lipid efflux, and sperm capacitation potential.

C. Lazure, R. Moreau, P. Manjunath, 1998, Biochemical and biophysical research communications.

Rat plasma kallikrein: purification, NH2-terminal sequencing and development of a specific radioimmunoassay.

N. Seidah, S. Benjannet, M. Chrétien, 1989, Biochimica et Biophysica Acta.

Primary structure of a high M r form of rat atrial natriuretic factor

M. Cantin, M. Chrétien, C. Lazure, 1984, FEBS letters.

The Atrial Natriuretic Factor Purification, Isolation of the Peptide and of Prepro ANF, and Physiological Studies

N. Seidah, E. Schiffrin, M. Cantin, 1986 .

Structure-activity relationships of atrial natriuretic factor (ANF). II. Effect of chain-length modifications on vascular reactivity.

N. Seidah, M. Cantin, M. Chrétien, 1985, Biochemical and biophysical research communications.

Structure-activity relationships of atrial natriuretic factor (ANF). I. Natriuretic activity and relaxation of intestinal smooth muscle.

N. Seidah, M. Cantin, M. Chrétien, 1984, Biochemical and biophysical research communications.

The major androgen‐dependent protease in dog prostate belongs to the kallikrein family: confirmation by partial amino acid sequencing

N. Seidah, M. Chrétien, R. Leduc, 1984, FEBS letters.

Purification of three rat atrial natriuretic factors and their amino acid composition

N. Seidah, M. Cantin, M. Chrétien, 1983, FEBS letters.

The complete amino acid sequence of rat submaxillary gland tonin does contain the aspartic acid at the active site: confirmation by protein sequence analyses

N. Seidah, M. Chrétien, R. Leduc, 1987 .

Radiolabeled biotinyl peptides as useful reagents for the study of proteolytic enzymes.

M. Chrétien, A. Basak, C. Lazure, 1993, Analytical biochemistry.

Peptide Separation Using Guanidine-Hcl During Reverse-Phase High Performance Liquid Chromatography

N. Seidah, M. Chrétien, R. Leduc, 1985 .

The Possible Role of Plasma Kallikrein in Pro-Hormone and Pro-Enzyme Processing

N. Seidah, S. Benjannet, M. Chrétien, 1988 .

Syntheses of argininal semicarbazone containing peptides and their applications in the affinity chromatography of serine proteinases.

N. Seidah, M. Chrétien, J. A. Cromlish, 2009, International journal of peptide and protein research.

Complete amino acid sequence of Shigella toxin B-chain. A novel polypeptide containing 69 amino acids and one disulfide bridge.

N. Seidah, M. Chrétien, G. Keusch, 1986, The Journal of biological chemistry.

Regulation of carbonic anhydrase III by thyroid hormone: opposite modulation in slow- and fast-twitch skeletal muscle.

M. Chrétien, C. Lazure, R. Tremblay, 1987, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Isolation and characterization of the major proteins of ram seminal plasma

C. Lazure, A. Bergeron, P. Manjunath, 2005, Molecular reproduction and development.

Isolation and Characterization of Gelatin-Binding Bison Seminal Vesicle Secretory Proteins1

C. Lazure, A. Bergeron, P. Manjunath, 2004, Biology of reproduction.

Isolation and characterization of gelatin-binding proteins from goat seminal plasma

C. Lazure, P. Manjunath, M. Villemure, 2003, Reproductive biology and endocrinology : RB&E.

Topographical Analysis of the Torpedo Marmorata Acetylcholine Receptor by Energy Transfer Photoaffinity Labeling Using Aryldiazonium Derivatives

J. Changeux, C. Mulle, M. Chrétien, 1989 .

Amino acid sequence of homologous rat atrial peptides: natriuretic activity of native and synthetic forms.

N. Seidah, R. Nutt, S. Brady, 1984, Proceedings of the National Academy of Sciences of the United States of America.

The production by alternate splicing of two mRNAs differing by one codon could be an intrinsic property of neuroendocrine protein 7B2 gene expression in man.

N. Seidah, M. Chrétien, C. Lazure, 1991, Biochemical and biophysical research communications.

The propeptide Asn1-Tyr126 is the storage form of rat atrial natriuretic factor.

N. Seidah, M. Cantin, M. Chrétien, 1987, The Biochemical journal.

Identification of a biologically active circulating form of rat atrial natriuretic factor.

N. Seidah, E. Schiffrin, M. Cantin, 1985, Biochemical and biophysical research communications.

Identification, Purification, and Characterization of the Molecular Forms of Aplysia californica Peptidylglycine α‐Amidating Enzyme

V. Castellucci, M. Chrétien, C. Lazure, 1996 .

Carboxyl-terminal disulfide bond of acid sphingomyelinase is critical for its secretion and enzymatic function.

I. Iatan, I. Wada, C. Lazure, 2007, Biochemistry.

Purification and primary structure of pro-aldosterone secretion inhibitory factor from bovine adrenal chromaffin cells.

M. Chrétien, C. Lazure, T. Nguyen, 1989, Molecular endocrinology.

Melanin concentrating hormone. V. Isolation and characterization of alpha-melanocyte-stimulating hormone from frog pituitary glands.

H. Vaudry, B. Jenks, M. Chrétien, 1989, Life sciences.

The amino acid sequences of frog heart atrial natriuretic‐like peptide and mammalian ANF are closely related

H. Vaudry, M. Chrétien, C. Lazure, 1988, FEBS letters.

Complete amino acid sequence of a VLDV-type neurophysin from ostrich differs markedly from known mammalian neurophysins.

M. Chrétien, C. Lazure, R. Naudé, 2009, International journal of peptide and protein research.

Bovine adrenal chromaffin granules are a site of synthesis of atrial natriuretic factor.

N. Seidah, M. Chrétien, C. Lazure, 1987, Biochemical and biophysical research communications.

Isolation from human seminal plasma of an abundant 16-kDa protein originating from the prostate, its identification with a 94-residue peptide originally described as beta-inhibin.

N. Seidah, M. Chrétien, J. Tremblay, 1987, Journal of andrology.

Purification and sequence determination of bovine atrial natriuretic factor.

N. Seidah, M. Cantin, M. Chrétien, 1986, Life Science.

ANF (Arg 101--Tyr 126) is the peptide secreted by rat atrial cardiocytes in culture.

N. Seidah, M. Cantin, M. Chrétien, 1985, Biochemical and biophysical research communications.

Metabolism of radioiodinated carboxy-terminal fragments of bovine parathyroid hormone in normal and anephric rats.

C. Lazure, P. D'amour, 1985, Endocrinology.

Comparison of four different carboxylterminal tracers in a radioimmunoassay specific to the 68-84 region of human parathyroid hormone.

C. Lazure, P. D'amour, F. Labelle, 1984, Journal of immunoassay.

Purification and characterization of active recombinant rat kallikrein rK9.

L. Juliano, C. Lazure, Y. Courty, 2001, Biochimica et biophysica acta.

Enzymic characterization in vitro of recombinant proprotein convertase PC4.

N. Seidah, M. Chrétien, A. Basak, 1999, The Biochemical journal.

Granulins, a novel class of peptide from leukocytes.

C. Lazure, A. Bateman, H. Bennett, 1990, Biochemical and biophysical research communications.

Diversity and Gene Expression

N. Seidah, M. Chrétien, C. Lazure, 1988 .

Neuronal and Endocrine Peptides

N. Seidah, M. Chrétien, C. Lazure, 1988 .

Purification of cationic cystine-rich peptides from rat bone marrow. Primary structures and biological activity of the rat corticostatin family of peptides

C. Lazure, A. Bateman, H. Bennett, 1992, Regulatory Peptides.

Isolation and characterization of corticostatic peptides from guinea pig bone marrow.

C. Lazure, H. Bennett, J. Hu, 1991, Biochemical and biophysical research communications.

Tissue-specific expression of the prostatic secretory protein PSP94 in cynomolgus monkey (Macaca fascicularis.

N. Seidah, M. Chrétien, C. Lazure, 1988, Cellular and molecular biology.

Structure-activity relationships of atrial natriuretic factor (ANF). III. Correlation of receptor affinity with relative potency on aldosterone production in zona glomerulosa cells.

N. Seidah, M. Cantin, M. Chrétien, 1985, Biochemical and biophysical research communications.

Biochemical aspects of a new hormone: rat atrial natriuretic factor (rANF).

N. Seidah, E. Schiffrin, M. Cantin, 1985, Regulatory peptides. Supplement.

Amino acid sequence of rabbit kidney neutral endopeptidase 24.11 (enkephalinase) deduced from a complementary DNA.

N. Seidah, J. Mallet, M. Chrétien, 1987, The EMBO journal.

Notch1 antiapoptotic activity is abrogated by caspase cleavage in dying T lymphocytes

R. Sékaly, C. Lazure, L. Sabbagh, 2005, Cell Death and Differentiation.

Isolation and purification of Escherichia coli heat-stable enterotoxin of porcine origin.

N. Seidah, M. Chrétien, C. Lazure, 1982, Analytical biochemistry.

Correct processing and secretion of a human prostatic secretory protein (PSP94) in Escherichia coli.

N. Seidah, S. Benjannet, M. Chrétien, 1988, Gene.

Immunological identification and sequence characterization of a peptide derived from the processing of neuroendocrine protein 7B2

N. Seidah, M. Chrétien, C. Lazure, 1991, FEBS letters.

Prostatic kallikrein hK2, but not prostate‐specific antigen (hK3), activates single‐chain urokinase‐type plasminogen activator

C. Lazure, R. Tremblay, J. Dubé, 1997, International journal of cancer.

Evolution of mammalian apolipoprotein A-I and conservation of antigenicity: correlation with primary and secondary structure.

Y. Marcel, C. Lazure, B. Perret, 1997, Journal of lipid research.

Gene structure of semenogelin I and II. The predominant proteins in human semen are encoded by two homologous genes on chromosome 20.

H. Lilja, N. Spurr, C. Lazure, 1992, The Journal of biological chemistry.

General lysosomal hydrolysis can process prorenin accurately.

C. Lazure, T. Reudelhuber, C. Mercure, 2014, American journal of physiology. Regulatory, integrative and comparative physiology.

Human kallikrein hK2 has low kininogenase activity while prostate-specific antigen (hK3) has none.

F. Marceau, C. Lazure, D. Deperthes, 1997, Biochimica et biophysica acta.

The isolation and partial characterization of trypsinogen, pancreatic secretory trypsin inhibitor and multiple forms of chymotrypsinogen and trypsin from the pancreas of the ostrich (Struthio camelus).

C. Lazure, R. Naudé, A. Patthy, 1992, The International journal of biochemistry.

Insertion of hydrophilic amino acid residues in the signal peptide/membrane anchor domain of neprilysin (neutral endopeptidase-24.11) results in its cleavage: role of the position of insertion.

C. Lazure, P. Crine, X. -. Yang, 1994, Archives of biochemistry and biophysics.

Specificity of Prohormone Convertase 2 on Proenkephalin and Proenkephalin-related Substrates*

D. Steiner, I. Lindberg, L. Juliano, 1998, The Journal of Biological Chemistry.

Structure of non-( 184 ) PTH fragments secreted by parathyroid glands in primary and secondary hyperparathyroidism

C. Lazure, R. Zahradnik, J. Lavigne, 2015 .

Sequence diversity within a subgroup of mouse immunoglobulin kappa chains controlled by the IgK-Ef2 locus

C. Lazure, W. Hum, D. Gibson, 1981, The Journal of experimental medicine.

Structure and genetic control of Vk-1 light chains

C. Lazure, W. Hum, S. Maclean, 1984 .

Isolation and primary structure of the three major forms of granulin-like peptides from hematopoietic tissues of a teleost fish (Cyprinus carpio).

C. Lazure, H. Bennett, D. Belcourt, 1993, The Journal of biological chemistry.

Processing of Peptide Hormone and Neuropeptide Precursors1

N. Seidah, M. Chrétien, C. Lazure, 1984 .

Phospholipase A2 from bovine seminal plasma is a platelet-activating factor acetylhydrolase.

S. Soubeyrand, C. Lazure, P. Manjunath, 1998, The Biochemical journal.

Processing of chromogranins in chromaffin cell culture: effects of reserpine and alpha-methyl-p-tyrosine.

A. Laslop, C. Lazure, R. Fischer‐Colbrie, 1996, The Biochemical journal.

Isolation and Purification of Escherichia coli Heat-Stable Enterotoxin of Porcine Origin 1

N. Seidah, M. Chrétien, C. Lazure, 1983 .

Role of Ostm1 Cytosolic Complex with Kinesin 5B in Intracellular Dispersion and Trafficking

N. Seidah, J. Vacher, S. Benjannet, 2015, Molecular and Cellular Biology.

Dog prostate arginine esterase is related to human prostate specific antigen.

C. Lazure, R. Tremblay, J. Dubé, 1986, Clinical and investigative medicine. Medecine clinique et experimentale.

Molecular cloning and sequence of the cDNA for a 94-amino-acid seminal plasma protein secreted by the human prostate.

N. Seidah, S. Benjannet, C. Lazure, 1987, DNA.

Isolation of prostatic kallikrein hK2, also known as hGK-1, in human seminal plasma.

C. Lazure, J. Hébert, D. Deperthes, 1995, Biochimica et biophysica acta.

Disruption of Proprotein Convertase 1/3 (PC1/3) Expression in Mice Causes Innate Immune Defects and Uncontrolled Cytokine Secretion*

N. Seidah, Xiaorong Zhu, D. Steiner, 2012, The Journal of Biological Chemistry.

Complementary methods to assist subcellular fractionation in organellar proteomics

C. Lazure, D. Gauthier, Daniel J Gauthier, 2008, Expert review of proteomics.

Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2.

N. Seidah, M. Marcinkiewicz, S. Benjannet, 1991, Molecular endocrinology.

Functional diversity of bioactive peptides in the nervous system itself: “How the brain may understand”

N. Seidah, M. Chrétien, C. Lazure, 1989, Bioscience reports.

N-terminal truncated forms of insulin-like growth factor binding protein-3 in the peritoneal fluid of women without laparoscopic evidence of endometriosis. Le groupe d'investigation en gynécologie.

M. Koutsilieris, C. Lazure, A. Lemay, 1995, Fertility and sterility.

Release of a 22-kDa protein derived from the amino-terminal domain of the 49-kDa NIa of turnip mosaic potyvirus in Escherichia coli.

C. Lazure, J. Laliberté, H. Chatel, 1992, Virology.

Sequence of the 3'-terminal region of turnip mosaic virus RNA and the capsid protein gene.

C. Lazure, J. Laliberté, M. Tremblay, 1990, The Journal of general virology.

The production of the ostrich NH2-terminal POMC fragment requires cleavage at a unique signal peptidase site

M. Chrétien, D. Litthauer, C. Lazure, 1993, Peptides.

GENETIC CONTROL OF KAPPA LIGHT CHAINS identification of 8 BALB

C. Lazure, D. Gibson, 2003 .

Differences Expressed in Normal BALB / c and NZB Light Chains

C. Lazure, W. Hum, D. Gibson, 2003 .

Amino acids of the Torpedo marmorata acetylcholine receptor alpha subunit labeled by a photoaffinity ligand for the acetylcholine binding site.

J. Changeux, M. Chrétien, J. Giraudat, 1988, Biochemistry.

The major dog pancreas protein recognized by an antiserum to dog prostate kallikrein is the anionic trypsin.

C. Lazure, D. Deperthes, R. Tremblay, 1993, The International journal of biochemistry.

Utilization of a new biotinylation reagent in the development of a nondiscriminatory investigative approach for the study of cell surface proteins

C. Lazure, B. Gibbs, N. Rabah, 2004, Proteomics.

Post-translational Processing of β-Secretase (β-Amyloid-converting Enzyme) and Its Ectodomain Shedding

Louise Wickham, N. Seidah, S. Benjannet, 2001, The Journal of Biological Chemistry.

Gene Inactivation of Proprotein Convertase Subtilisin/Kexin Type 9 Reduces Atherosclerosis in Mice

A. Prat, N. Seidah, C. Lazure, 2012, Circulation.

The large subunit of replication factor C is a substrate for caspase‐3 in vitro and is cleaved by a caspase‐3‐like protease during Fas‐mediated apoptosis

J. Hurwitz, R. Sékaly, F. Uhlmann, 1997, The EMBO journal.

The cDNA structure of rat plasma kallikrein.

N. Seidah, M. Chrétien, G. Lutfalla, 1989, DNA.

Identification of the Paired Basic Convertases Implicated in HIV gp160 Processing Based on in Vitro Assays and Expression in CD4+ Cell Lines*

C Di Bello, J M Ruysschaert, N. Seidah, 1996, The Journal of Biological Chemistry.

Flow cytometry‐assisted purification and proteomic analysis of the corticotropes dense‐core secretory granules

R. Mains, C. Lazure, F. Ferraro, 2008, Proteomics.

Identification of glandular kallikrein in dog pancreas and determination of its tissue distribution.

C. Lazure, D. Deperthes, R. Tremblay, 1995, Biochimica et biophysica acta.

High concentrations of the macrophage migration inhibitory factor in human seminal plasma and prostatic tissues.

C. Lazure, R. Tremblay, G. Frenette, 1998, Archives of andrology.

Annexin A2 Reduces PCSK9 Protein Levels via a Translational Mechanism and Interacts with the M1 and M2 Domains of PCSK9*

N. Seidah, J. Mayne, J. Hamelin, 2014, The Journal of Biological Chemistry.

Proteases and posttranslational processing of prohormones: a review.

N. Seidah, M. Chrétien, C. Lazure, 1983, Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire.

Secretion of a type II integral membrane protein induced by mutation of the transmembrane segment.

C. Lazure, P. Crine, G. Boileau, 1997, The Biochemical journal.

The isoforms of proprotein convertase PC5 are sorted to different subcellular compartments

N. Seidah, M. Marcinkiewicz, D. Malide, 1996, The Journal of cell biology.

Purification of enzymatically active kallikrein hK2 from human seminal plasma.

C. Lazure, D. Deperthes, R. Tremblay, 1997, Biochimica et biophysica acta.

Characterization of ostrich (Struthio camelus) β‐microseminoprotein (MSP): Ideication of homologous sequences in EST databases and analysis of their evolution during speciation

C. Lazure, M. Mbikay, R. Naudé, 2001, Protein science : a publication of the Protein Society.

Novel approach to rapid and sensitive localization of protein disulfide bridges by high-performance liquid chromatography and electrochemical detection

N. Seidah, M. Chrétien, C. Lazure, 1985 .

In Vitro Characterization of the Novel Proprotein Convertase PC7*

N. Seidah, S. Benjannet, M. Chrétien, 1997, The Journal of Biological Chemistry.

Processing Specificity and Biosynthesis of the Drosophila melanogaster Convertases dfurin1, dfurin1-CRR, dfurin1-X, and dfurin2 (*)

N. Seidah, A. Roebroek, W. V. D. Van de Ven, 1995, The Journal of Biological Chemistry.

Proteolytic degradation of rat growth hormone-releasing factor(1–29) amide in rat pituitary and hypothalamus

C. Lazure, P. Gaudreau, L. Boulanger, 1993, Brain Research.

Molecular heterogeneity of pro-atrial natriuretic factor.

M. Cantin, M. Chrétien, C. Lazure, 1989, The Journal of biological chemistry.

The major 40‐kDa glycoprotein in human prostatic fluid is identical to Zn‐α2‐glycoprotein

M. Chrétien, C. Lazure, G. Paradis, 1987 .

Processed forms of neuroendocrine proteins 7B2 and secretogranin II are found in porcine pituitary extracts.

N. Seidah, S. Benjannet, M. Chrétien, 2009, International journal of peptide and protein research.

Two-dimensional immunoblotting analysis and immunocytochemical localization of the secretory polypeptide 7B2 in adrenal medulla

M. Marcinkiewicz, S. Benjannet, J. Falgueyret, 1988, Neuroscience Letters.

The peptidase zymogen proregions: nature's way of preventing undesired activation and proteolysis.

C. Lazure, 2002, Current pharmaceutical design.

[Endorphins 1989: neuroendocrine aspects].

N. Seidah, M. Chrétien, R. Morcos, 1989, Revue neurologique.

Aldosterone secretion inhibitory factor: a novel neuropeptide in bovine chromaffin cells.

M. Chrétien, C. Lazure, A. De Léan, 1989, Endocrinology.

Enzymic characterization of murine and human prohormone convertase-1 (mPC1 and hPC1) expressed in mammalian GH4C1 cells.

N. Seidah, S. Benjannet, M. Chrétien, 1993, The Biochemical journal.

A novel gene family encoding proteins with highly differing structure because of a rapidly evolving exon

C. Lazure, Å. Lundwall, 1995, FEBS letters.

In Vitro Cleavage of Internally Quenched Fluorogenic Human Proparathyroid Hormone and Proparathyroid-related Peptide Substrates by Furin

N. Seidah, G. Hendy, C. Lazure, 1998, The Journal of Biological Chemistry.

cDNA sequence of neuroendocrine protein 7B2 expressed in beta cell tumors of transgenic mice.

D. Hanahan, N. Seidah, M. Chrétien, 2009, International journal of peptide and protein research.

Subcellular fractionation of pituitary neurointermediate lobes: revelation of various basic proteases.

N. Seidah, M. Chrétien, J. A. Cromlish, 1984, Endocrinology.

Design of octadecapeptide loop structures by modeling the active-site region of barley serine proteinase inhibitor-2

N. Seidah, M. Chrétien, A. Basak, 1994 .

Amino Terminal Sequence of 7B2: A Novel, Human Pituitary/Brain Polypeptide Present in Gonadotrophs and Released by LHRH

N. Seidah, M. Marcinkiewicz, S. Benjannet, 1987 .

Single Amino Acid Substitution in the PC1/3 Propeptide Can Induce Significant Modifications of Its Inhibitory Profile toward Its Cognate Enzyme*

C. Lazure, N. Rabah, D. Gauthier, 2006, Journal of Biological Chemistry.