Junhao Li

发表

Effects of protein flexibility and active site water molecules on the prediction of sites of metabolism for cytochrome P450 2C19 substrates.

Weihua Li, Guixia Liu, Yun Tang, 2016, Molecular bioSystems.

Toward Novel [18F]Fluorine-Labeled Radiotracers for the Imaging of α-Synuclein Fibrils

P. Svenningsson, W. Weber, Junhao Li, 2022, Frontiers in Aging Neuroscience.

Effect of Methamphetamine on Spectral Binding, Ligand Docking and Metabolism of Anti-HIV Drugs with CYP3A4

Weihua Li, N. Vaidya, Anil Kumar, 2016, PloS one.

Unraveling the Abnormal Molecular Mechanism of Suicide Inhibition of Cytochrome P450 3A4

Yaoquan Tu, Junhao Li, G. Baryshnikov, 2022, J. Chem. Inf. Model..

Computational Insight Into Vitamin K1 ω-Hydroxylation by Cytochrome P450 4F2

Weihua Li, Guixia Liu, Yun Tang, 2018, Front. Pharmacol..

Enhanced Methamphetamine Metabolism in Rhesus Macaque as Compared with Human: An Analysis Using a Novel Method of Liquid Chromatography with Tandem Mass Spectrometry, Kinetic Study, and Substrate Docking

Weihua Li, Anil Kumar, H. Fox, 2014, Drug Metabolism and Disposition.

DMD059378 2097..2108

Weihua Li, Anil Kumar, H. Fox, 2014 .

Enhanced methamphetamine metabolism in rhesus macaque as compared to human: An analysis using a novel LCMS/MS method, kinetic study, and substrate docking

Weihua Li, Anil Kumar, H. Fox, 2014 .

Efficient characterization of multiple binding sites of small molecule imaging ligands on amyloid-beta, 4-repeat/full-length tau and alpha-synuclein

R. Riek, R. Nitsch, A. Nordberg, 2023, bioRxiv.

Dissecting the Binding Profile of PET Tracers to Corticobasal Degeneration Tau Fibrils

H. Ågren, A. Nordberg, Junhao Li, 2021, ACS chemical neuroscience.

Influence of Ethanol on Darunavir Hepatic Clearance and Intracellular PK/PD in HIV-Infected Monocytes, and CYP3A4-Darunavir Interactions Using Inhibition and in Silico Binding Studies

Weihua Li, B. Meibohm, Junhao Li, 2017, Pharmaceutical Research.

Effect of Ethanol on the Metabolic Characteristics of HIV-1 Integrase Inhibitor Elvitegravir and Elvitegravir/Cobicistat with CYP3A: An Analysis Using a Newly Developed LC-MS/MS Method

Weihua Li, Bernd Meibohm, Junhao Li, 2016, PloS one.

Computational insights into the different catalytic activities of CYP3A4 and CYP3A5 toward schisantherin E

Weihua Li, Zengrui Wu, Guixia Liu, 2019, Chemical biology & drug design.

Computational Insight into the Allosteric Activation Mechanism of Farnesoid X Receptor

Zengrui Wu, Weihua Li, Guixia Liu, 2020, J. Chem. Inf. Model..

Dissecting the Structural Plasticity and Dynamics of Cytochrome P450 2B4 by Molecular Dynamics Simulations

Weihua Li, Yun Tang, Junhao Li, 2020, J. Chem. Inf. Model..

[Progress in study of selective ERβ ligands].

Guixia Liu, Yun Tang, Junhao Li, 2015, Yao xue xue bao = Acta pharmaceutica Sinica.

A donor-acceptor triptycene-coumarin hybrid dye featuring a charge separated excited state and AIE properties.

Junhao Li, Kaiyan Lou, Wei Wang, 2016, Organic & biomolecular chemistry.

A highly selective C-rhamnosyltransferase from Viola tricolor and insights into its mechanisms

Z. Wang, Junhao Li, X. Qiao, 2023, Acta pharmaceutica Sinica. B.

Mechanistic Insights into the Regio‐ and Stereoselectivities of Testosterone and Dihydrotestosterone Hydroxylation Catalyzed by CYP3A4 and CYP19A1

Weihua Li, Yun Tang, Yaoquan Tu, 2020, Chemistry.

Homotropic Cooperativity of Midazolam Metabolism by Cytochrome P450 3A4: Insight from Computational Studies

Weihua Li, Yun Tang, Yaoquan Tu, 2021, J. Chem. Inf. Model..

Influence of Ethanol on Darunavir Hepatic Clearance and Intracellular PK/PD in HIV-Infected Monocytes, and CYP3A4-Darunavir Interactions Using Inhibition and in Silico Binding Studies

Weihua Li, B. Meibohm, Junhao Li, 2017, Pharmaceutical Research.

Computational insights into inhibitory mechanism of azole compounds against human aromatase

Weihua Li, Yun Tang, Guixia Liu, 2015 .

Computational Investigation of Ligand Binding to the Peripheral Site in CYP3A4: Conformational Dynamics and Inhibitor Discovery

Guixia Liu, Yun Tang, Weihua Li, 2017, J. Chem. Inf. Model..

Interactions of omeprazole-based analogues with cytochrome P450 2C19: a computational study.

Zengrui Wu, Weihua Li, Yun Tang, 2016, Molecular bioSystems.

Insight into the Binding of First- and Second-Generation PET Tracers to 4R and 3R/4R Tau Protofibrils

B. Långström, A. Nordberg, Junhao Li, 2023, ACS chemical neuroscience.

Effects of protein flexibility and active site water molecules on the prediction of sites of metabolism for cytochrome P450 2C19 substrates.

Weihua Li, Guixia Liu, Yun Tang, 2016, Molecular bioSystems.

In silico studies of ASEM analogues targeting α7-nAChR and experimental verification

H. Ågren, B. Långström, C. Halldin, 2021, RSC advances.