Kong Chen

Joyce S Lee, J. Golden, W. Xu, 2020, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

IL-17 Receptor Signaling in the Lung Epithelium Is Required for Mucosal Chemokine Gradients and Pulmonary Host Defense against K. pneumoniae.

Janet S. Lee, Wei Chen, S. Gaffen, 2016, Cell host & microbe.

Antiinflammatory effects of bromodomain and extraterminal domain inhibition in cystic fibrosis lung inflammation.

Wei Chen, S. Wenzel, M. Myerburg, 2016, JCI insight.

Nrf2 through Aryl Hydrocarbon Receptor Regulates IL-22 Response in CD4+ T Cells

A. Awasthi, T. Oury, Pawan Kumar, 2021, The Journal of Immunology.

Single cell RNA sequencing identifies IGFBP5 and QKI as ciliated epithelial cell genes associated with severe COPD

F. Sciurba, S. Shapiro, M. Rojas, 2020, Respiratory Research.

Pneumocystis-Driven Inducible Bronchus-Associated Lymphoid Tissue Formation Requires Th2 and Th17 Immunity.

J. Kolls, Kong Chen, J. Rangel-Moreno, 2017, Cell Reports.

STAT1 Represses Cytokine-Producing Group 2 and Group 3 Innate Lymphoid Cells during Viral Infection

K. Boyd, J. Kolls, R. Peebles, 2017, The Journal of Immunology.

Innate Lymphoid Cells and Acute Respiratory Distress Syndrome.

J. Kolls, Kong Chen, 2016, American journal of respiratory and critical care medicine.

Vitamin D Regulation of OX40 Ligand in Immune Responses to Aspergillus fumigatus

J. Kolls, Kong Chen, N. Nguyen, 2013, Infection and Immunity.

Acute Alcohol Intoxication Impairs Methicillin-Resistant Staphylococcus aureus Clearance in the Lung by Impeding Epithelial Production of Reg3γ

J. Kolls, S. Choi, Kong Chen, 2014, Infection and Immunity.

Good and bad lipids in the lung

J. Kolls, Kong Chen, 2010, Nature Medicine.

Transformer Enables Reference Free And Unsupervised Analysis of Spatial Transcriptomics

Heng Huang, Xinjun Wang, Zhongli Xu, 2022, bioRxiv.

IL-17RA Is Required for CCL2 Expression, Macrophage Recruitment, and Emphysema in Response to Cigarette Smoke

A. M. Houghton, J. Alcorn, S. Shapiro, 2011, PloS one.

Interleukin-22 (IL-22) Binding Protein Constrains IL-22 Activity, Host Defense, and Oxidative Phosphorylation Genes during Pneumococcal Pneumonia

J. Alcorn, S. Gaffen, J. Kolls, 2019, Infection and Immunity.

Regnase-1 Deficiency Restrains Klebsiella pneumoniae Infection by Regulation of a Type I Interferon Response

S. Gaffen, Kong Chen, P. Biswas, 2021, bioRxiv.

CD16+CD163+ monocytes traffic to sites of inflammation during necrotizing enterocolitis in premature infants

S. Snapper, P. Liu, Kong Chen, 2021, The Journal of experimental medicine.

Endotoxin stabilizes protein arginine methyltransferase 4 (PRMT4) protein triggering death of lung epithelia

Janet S. Lee, T. Nyunoya, R. Mallampalli, 2021, Cell Death & Disease.

PTENtiating CFTR for Antimicrobial Immunity.

J. Kolls, Kong Chen, 2017, Immunity.

A Bayesian mixture model for clustering droplet-based single-cell transcriptomic data from population studies

Li Chen, Wei Chen, Ying Ding, 2019, Nature Communications.

Bacterial and Pneumocystis Infections in the Lungs of Gene-Knockout Rabbits with Severe Combined Immunodeficiency

Liang Ma, M. Hoenerhoff, Jifeng Zhang, 2018, Front. Immunol..

T cell-mediated host immune defenses in the lung.

J. Kolls, Kong Chen, 2013, Annual review of immunology.

Pulmonary Th17 Antifungal Immunity Is Regulated by the Gut Microbiome

W. Ouyang, D. Sheppard, K. Bibby, 2016, The Journal of Immunology.

Dysregulation in lung immunity — The protective and pathologic Th17 response in infection

J. Kolls, Kong Chen, Emily E. Way, 2013, European journal of immunology.

Patients with cystic fibrosis have inducible IL-17+IL-22+ memory cells in lung draining lymph nodes.

A. Ray, P. Ray, J. Kolls, 2013, The Journal of allergy and clinical immunology.

CD4+ T Cell Dysfunction in Severe COVID-19 Disease is TNFα/TNFRI-Dependent.

Bill B. Chen, M. Saul, D. Triulzi, 2022, American journal of respiratory and critical care medicine.

Induction and stability of human Th17 cells require endogenous NOS2 and cGMP-dependent NO signaling

K. Odunsi, T. Billiar, J. Kolls, 2013, The Journal of experimental medicine.

Artificial-cell-type aware cell-type classification in CITE-seq

Wei Chen, Jin Gu, Hongyi Xin, 2020, bioRxiv.

A Bayesian mixture model for clustering droplet-based single-cell transcriptomic data from population studies

Hongyi Xin, Ying Ding, J. Kolls, 2019, Nature Communications.

Protein arginine N-methyltransferase 4 (PRMT4) contributes to lymphopenia in experimental sepsis

Janet S. Lee, T. Nyunoya, Yingze Zhang, 2022, Thorax.

BREM-SC: a bayesian random effects mixture model for joint clustering single cell multi-omics data

Wei Chen, Heng Huang, Ying Ding, 2020, bioRxiv.

A Bayesian mixture model for clustering droplet-based single-cell transcriptomic data from population studies

Zhe Sun, Wei Chen, Ying Ding, 2018, Nature Communications.

GMM-Demux: sample demultiplexing, multiplet detection, experiment planning, and novel cell-type verification in single cell sequencing

R. Duerr, Hongyi Xin, Jiadi Luo, 2020, Genome Biology.

Sample demultiplexing, multiplet detection, experiment planning and novel cell type verification in single cell sequencing

Wei Chen, Hongyi Xin, Qi Yan, 2019, bioRxiv.

Lipopolysaccharide-Mediated Chronic Inflammation Promotes Tobacco Carcinogen–Induced Lung Cancer and Determines the Efficacy of Immunotherapy

Zhong Chen, Xiaoping Liu, Kong Chen, 2020, Cancer Research.

FBXO17 promotes cell proliferation through activation of Akt in lung adenocarcinoma cells

Yutong Zhao, R. Mallampalli, Kong Chen, 2018, Respiratory Research.

Integrative analysis of spatial transcriptome with single-cell transcriptome and single-cell epigenome in mouse lungs after immunization

Jiebiao Wang, Xinjun Wang, Zhongli Xu, 2021, bioRxiv.

Beta-agonist Exposure Preferentially Impacts Lung Macrophage Cyclic AMP Related Gene Expression in Asthma and Asthma COPD Overlap Syndrome.

B. Modena, S. Wenzel, M. Rojas, 2021, American journal of physiology. Lung cellular and molecular physiology.

Insulin is expressed by enteroendocrine cells during human fetal development

S. Itzkovitz, K. Bahar Halpern, Kong Chen, 2021, Nature Medicine.

Interluekin-17A (IL17A).

J. Kolls, Kong Chen, 2017, Gene.

Anti-CD20 Antibody Therapy and Susceptibility to Pneumocystis Pneumonia

J. Kolls, Kong Chen, W. Elsegeiny, 2015, Infection and Immunity.

Dose-Dependent Suppression of Cytokine production from T cells by a Novel Phosphoinositide 3-Kinase Delta Inhibitor

L. Kane, J. Kolls, Kong Chen, 2013, Scientific Reports.

MCPIP1 Endoribonuclease Activity Negatively Regulates Interleukin-17-Mediated Signaling and Inflammation.

S. Gaffen, T. Smithgall, J. Kolls, 2015, Immunity.

CD4+ T-Cell Dysfunction in Severe COVID-19 Disease Is Tumor Necrosis Factor-α/Tumor Necrosis Factor Receptor 1–Dependent

Bill B. Chen, D. Triulzi, D. Kass, 2022, American Journal of Respiratory and Critical Care Medicine.

CD4+ T cell lymphopenia and dysfunction in severe COVID-19 disease is autocrine TNF-α/TNFRI-dependent

Bill B. Chen, M. Saul, J. Pilewski, 2021, bioRxiv.

Critical Role of IL-17RA in Immunopathology of Influenza Infection

J. Alcorn, J. Witztum, J. Kolls, 2009, The Journal of Immunology.

Immunopathology of Influenza Infection Critical Role of IL-17 RA in Ross

J. Alcorn, J. Witztum, J. Kolls, 2009 .

A resource of high-quality and versatile nanobodies for drug delivery

D. Schneidman-Duhovny, Baoli Hu, Jiadi Luo, 2021, iScience.

Murine models of Pneumocystis infection recapitulate human primary immune disorders.

J. Alcorn, G. Dai, J. Kolls, 2017, JCI insight.

Spermidine dampens inflammation by directly inhibiting Th17 cytokine production through a PRDX1 associated antioxidant pathway

Ying-Ru Pan, Jiadi Luo, C. Erb, 2021, bioRxiv.

Conserved natural IgM antibodies mediate innate and adaptive immunity against the opportunistic fungus Pneumocystis murina

J. Alcorn, S. Plevy, J. Kolls, 2010, The Journal of experimental medicine.

A Novel CD4+ T Cell-Dependent Murine Model of Pneumocystis-driven Asthma-like Pathology.

Kevin J. McHugh, J. Alcorn, S. Wenzel, 2016, American journal of respiratory and critical care medicine.

Th17 cell based vaccines in mucosal immunity.

Pawan Kumar, J. Kolls, Kong Chen, 2013, Current opinion in immunology.

γδ T cells attenuate bleomycin-induced fibrosis through the production of CXCL10.

T. Oury, J. Kolls, S. Choi, 2011, The American journal of pathology.

A road map from single-cell transcriptome to patient classification for the immune response to trauma

D. Angus, Y. Vodovotz, L. Moldawer, 2020, JCI insight.

Modulation of tissue resident memory T cells by glucocorticoids after acute cellular rejection in lung transplantation

P. Sims, Yingze Zhang, Kong Chen, 2022, The Journal of experimental medicine.

Tumor Necrosis Factor Alpha Regulates Skeletal Myogenesis by Inhibiting SP1 Interaction with cis-Acting Regulatory Elements within the Fbxl2 Gene Promoter

Bill B. Chen, R. Mallampalli, Kong Chen, 2020, Molecular and Cellular Biology.

Transcriptomic responses to Ivacaftor and prediction of Ivacaftor clinical responsiveness.

Wei Chen, J. Kolls, J. Pilewski, 2019, American journal of respiratory cell and molecular biology.

IL-17 is a potent synergistic factor with GM-CSF in mice in stimulating myelopoiesis, dendritic cell expansion, proliferation, and functional enhancement.

J. Kolls, A. Ramsay, Kong Chen, 2010, Experimental hematology.

Reduced antigenicity of Omicron lowers host serologic response

H. Wolfson, J. Tubiana, D. Schneidman-Duhovny, 2022, bioRxiv.

RNA-seq in Pulmonary Medicine: How Much Is Enough?

Wei Chen, S. Wenzel, A. Ray, 2015, American journal of respiratory and critical care medicine.

Simultaneous Measurement of Surface Proteins and Gene Expression from Single Cells.

Jiadi Luo, C. Erb, Kong Chen, 2020, Methods in molecular biology.

Epigenetic and Transcriptomic Regulation of Lung Repair during Recovery from Influenza Infection.

Kevin J. McHugh, J. Alcorn, P. Benos, 2017, The American journal of pathology.

Acinetobacter baumannii Infection and IL-17 Mediated Immunity

Kong Chen, Zihe Yan, Renjing Hu, 2016, Mediators of inflammation.

Dectin immunoadhesins and Pneumocystis pneumonia 1

J. Kolls, Kong Chen, C. Steele, 2013 .

Airway Transcriptome Analysis and Immune Proteome Profiling of the Lung Allograft Reveals Novel Immune Signatures in Chronic Lung Allograft Dysfunction

J. Pilewski, Yingze Zhang, Kong Chen, 2019, The Journal of Heart and Lung Transplantation.

Biophysical Studies on the Site-Selective Binding of a Synthesized Selenium–Quercetin Complex on a Protein

Kong Chen, Huaxin Zhang, 2012, Journal of Solution Chemistry.

AIM2 Inflammasome Is Critical for Influenza-Induced Lung Injury and Mortality

J. Alcorn, Wei Chen, S. Fan, 2017, The Journal of Immunology.

This information is current as Mortality Influenza-Induced Lung Injury and AIM 2 Inflammasome Is Critical for

J. Alcorn, S. Fan, J. Kolls, 2017 .

Phagocytosis is a primary determinant of pulmonary clearance of clinical Klebsiella pneumoniae isolates

Janet S. Lee, D. Stolz, Kong Chen, 2023, Frontiers in Cellular and Infection Microbiology.

Vaccine approaches for multidrug resistant Gram negative infections.

J. Kolls, Kong Chen, B. Campfield, 2014, Current opinion in immunology.

Faculty Opinions recommendation of Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in T(H)17 cells.

J. Kolls, Kong Chen, 2012 .

Monocyte production of C1q potentiates CD8+ T cell effector function following respiratory viral infection

T. Oury, Kong Chen, M. Reyes-Múgica, 2023, bioRxiv.

Epigenetic Regulation of IL-17-Induced Chemokines in Lung Epithelial Cells

S. Fan, J. Kolls, Jiadi Luo, 2019, Mediators of inflammation.

Single-cell atlas of the human neonatal small intestine affected by necrotizing enterocolitis.

S. Itzkovitz, J. Pober, Kong Chen, 2023, PLoS biology.

Single cell atlas of the neonatal small intestine with necrotizing enterocolitis

S. Itzkovitz, J. Pober, Kong Chen, 2022, bioRxiv.

Reduced B cell antigenicity of Omicron lowers host serologic response

H. Wolfson, J. Tubiana, D. Schneidman-Duhovny, 2022, Cell Reports.

Murine models of Pneumocystis infection recapitulate human primary immune disorders.

J. Alcorn, G. Dai, J. Kolls, 2018, JCI insight.

T cell-mediated host immune defenses in the lung.

J. Kolls, Kong Chen, 2013, Annual review of immunology.

Amphiregulin couples IL1RL1+ regulatory T cells and cancer-associated fibroblasts to impede antitumor immunity

Lujia Chen, Xinghua Lu, B. Lu, 2023, Science advances.

Pneumocystis-Driven Inducible Bronchus-Associated Lymphoid Tissue Formation Requires Th2 and Th17 Immunity.

J. Kolls, Kong Chen, J. Rangel-Moreno, 2017, Cell reports.

Conserved natural IgM antibodies mediate innate and adaptive immunity against the opportunistic fungus Pneumocystis murina

J. Alcorn, S. Plevy, J. Kolls, 2010, The Journal of experimental medicine.

Analysis of Transcriptional Profiling of Immune Cells at the Single-Cell Level.

Kong Chen, A. Ferguson, 2020, Methods in molecular biology.