Piret Arukuusk

发表

Expressed therapeutic protein yields are predicted by transiently transfected mammalian cell population

Ü. Langel, Ly Porosk, Jekaterina Nebogatova, 2022, bioRxiv.

Effective in vivo gene delivery with reduced toxicity, achieved by charge and fatty acid -modified cell penetrating peptide

Elin Madli Peets, Ü. Langel, Piret Arukuusk, 2017, Scientific Reports.

PepFect14 peptide vector for efficient gene delivery in cell cultures.

I. Mäger, M. Pooga, Ü. Langel, 2013, Molecular pharmaceutics.

Glycosaminoglycans are required for translocation of amphipathic cell-penetrating peptides across membranes.

M. Pooga, Ü. Langel, Piret Arukuusk, 2016, Biochimica et biophysica acta.

Differential endosomal pathways for radically modified peptide vectors.

Ű. Langel, M. Pooga, Piret Arukuusk, 2013, Bioconjugate chemistry.

Characterization of Peptide-Oligonucleotide Complexes Using Electron Microscopy, Dynamic Light Scattering, and Protease Resistance Assay.

M. Pooga, Ly Porosk, Piret Arukuusk, 2019, Methods in molecular biology.

Novel Fatty Acid Modifications of Transportan 10

Ű. Langel, R. Sillard, Piret Arukuusk, 2010, International Journal of Peptide Research and Therapeutics.

Formulation of Stable and Homogeneous Cell-Penetrating Peptide NF55 Nanoparticles for Efficient Gene Delivery In Vivo

M. Pooga, R. Raid, Ü. Langel, 2017, Molecular therapy. Nucleic acids.

Cell-Penetrating Peptides Predicted From CASC3, AKIP1, and AHRR Proteins

Ü. Langel, Ly Porosk, Piret Arukuusk, 2021, Frontiers in Pharmacology.

Characteristics of Cell-Penetrating Peptide/Nucleic Acid Nanoparticles.

M. Pooga, Ü. Langel, Piret Arukuusk, 2016, Molecular pharmaceutics.

ACE2 peptide fragment interacts with several sites on the SARS-CoV-2 spike protein S1

J. Järv, A. Kuznetsov, Ü. Langel, 2020, bioRxiv.

Cell‐penetrating peptides recruit type A scavenger receptors to the plasma membrane for cellular delivery of nucleic acids

M. Pooga, Ü. Langel, Piret Arukuusk, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Optimization of in vivo DNA delivery with NickFect peptide vectors.

M. Pooga, Ü. Langel, Piret Arukuusk, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Cell-Penetrating Peptide and siRNA-Mediated Therapeutic Effects on Endometriosis and Cancer In Vitro Models

A. Salumets, Ü. Langel, Ly Porosk, 2021, Pharmaceutics.

The Formation of Nanoparticles between Small Interfering RNA and Amphipathic Cell-Penetrating Peptides

T. Tenson, Ü. Langel, Piret Arukuusk, 2017, Molecular therapy. Nucleic acids.

PepFects and NickFects for the Intracellular Delivery of Nucleic Acids.

M. Hällbrink, Ü. Langel, Piret Arukuusk, 2015, Methods in molecular biology.

Aggregation Limiting Cell-Penetrating Peptides Derived from Protein Signal Sequences

Ü. Langel, Ly Porosk, Jekaterina Nebogatova, 2023, International journal of molecular sciences.

Methods to follow intracellular trafficking of cell-penetrating peptides

K. Braeckmans, Ü. Langel, Piret Arukuusk, 2016, Journal of drug targeting.

Cell-penetrating peptides, PepFects, show no evidence of toxicity and immunogenicity in vitro and in vivo.

Ű. Langel, Piret Arukuusk, K. Kurrikoff, 2011, Bioconjugate chemistry.

Enhancement of siRNA transfection by the optimization of fatty acid length and histidine content in the CPP.

M. Pooga, Ü. Langel, Ly Porosk, 2019, Biomaterials science.

Translocation of cell-penetrating peptides across the plasma membrane is controlled by cholesterol and microenvironment created by membranous proteins.

M. Pooga, Ü. Langel, Piret Arukuusk, 2014, Journal of controlled release : official journal of the Controlled Release Society.

The Development of Cell-Penetrating Peptides for Efficient and Selective In Vivo Expression of mRNA in Spleen Tissue

P. Peterson, Ly Porosk, H. Härk, 2023, Pharmaceutics.

Predicting Transiently Expressed Protein Yields: Comparison of Transfection Methods in CHO and HEK293

Ü. Langel, Ly Porosk, Jekaterina Nebogatova, 2022, Pharmaceutics.

NickFect type of cell-penetrating peptides present enhanced efficiency for microRNA-146a delivery into dendritic cells and during skin inflammation.

L. Tserel, J. Wengel, M. Pooga, 2020, Biomaterials.

Allosteric Effect of Adenosine Triphosphate on Peptide Recognition by 3′5′-Cyclic Adenosine Monophosphate Dependent Protein Kinase Catalytic Subunits

J. Järv, R. Kivi, Piret Arukuusk, 2016, The Protein Journal.

NickFects, Phosphorylated Derivatives of Transportan 10 for Cellular Delivery of Oligonucleotides

M. Pooga, Ü. Langel, Piret Arukuusk, 2011, International Journal of Peptide Research and Therapeutics.

NickFects – novel cell-penetrating peptides. Design and uptake mechanism

Piret Arukuusk, 2013 .

New generation of efficient peptide-based vectors, NickFects, for the delivery of nucleic acids.

Ű. Langel, M. Pooga, Piret Arukuusk, 2013, Biochimica et biophysica acta.

The role of endocytosis in the uptake and intracellular trafficking of PepFect14-nucleic acid nanocomplexes via class A scavenger receptors.

M. Pooga, Ü. Langel, Piret Arukuusk, 2015, Biochimica et biophysica acta.

Porous silicon-cell penetrating peptide hybrid nanocarrier for intracellular delivery of oligonucleotides.

Ű. Langel, Piret Arukuusk, K. Kurrikoff, 2014, Molecular pharmaceutics.

Translocation of cell-penetrating peptides across the plasma membrane is controlled by cholesterol and microenvironment created by membranous proteins.

M. Pooga, Ü. Langel, Piret Arukuusk, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Effects of cargo molecules on membrane perturbation caused by transportan10 based cell-penetrating peptides.

Ű. Langel, Piret Arukuusk, F. Madani, 2014, Biochimica et biophysica acta.

Cell‐penetrating peptides recruit type A scavenger receptors to the plasma membrane for cellular delivery of nucleic acids

M. Pooga, Ü. Langel, Piret Arukuusk, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

ACE2 Peptide Fragment Interaction with Different S1 Protein Sites

J. Järv, A. Kuznetsov, Ü. Langel, 2021, International Journal of Peptide Research and Therapeutics.