C. Ortiz Mellet

发表

Trifaceted Mickey Mouse Amphiphiles for Programmable Self‐Assembly, DNA Complexation and Organ‐Selective Gene Delivery

Ana I. Carbajo‐Gordillo, M. González-Cuesta, J. L. Jiménez Blanco, 2021, Chemistry.

Cyclodextrin- and calixarene-based polycationic amphiphiles as gene delivery systems: a structure-activity relationship study.

V. Franceschi, G. Donofrio, F. Sansone, 2015, Organic & biomolecular chemistry.

Polycationic amphiphilic cyclodextrins as gene vectors: effect of the macrocyclic ring size on the DNA complexing and delivery properties.

J. L. Jiménez Blanco, C. Di Giorgio, C. Ortiz Mellet, 2012, Organic & biomolecular chemistry.

β-Cyclodextrin-based polycationic amphiphilic "click" clusters: effect of structural modifications in their DNA complexing and delivery properties.

F. Santoyo-González, C. Di Giorgio, C. Ortiz Mellet, 2011, The Journal of organic chemistry.

Cyclodextrin-based gene delivery systems.

J. M. Benito, C. Ortiz Mellet, J. G. García Fernández, 2011, Chemical Society reviews.

Insights in cellular uptake mechanisms of pDNA-polycationic amphiphilic cyclodextrin nanoparticles (CDplexes).

D. Vercauteren, J. M. Benito, C. Ortiz Mellet, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Polycationic amphiphilic cyclodextrins for gene delivery: synthesis and effect of structural modifications on plasmid DNA complex stability, cytotoxicity, and gene expression.

Nicolas Guilloteau, Alejandro Díaz-Moscoso, J. M. Benito, 2009, Chemistry.

Preorganized macromolecular gene delivery systems: amphiphilic beta-cyclodextrin "click clusters".

F. Santoyo-González, R. Salto, M. Girón, 2009, Organic & biomolecular chemistry.

Conformationally-locked N-glycosides with selective β-glucosidase inhibitory activity: identification of a new non-iminosugar-type pharmacological chaperone for Gaucher disease.

Yoshiyuki Suzuki, K. Higaki, E. Nanba, 2012, Journal of medicinal chemistry.

A Fluorescent sp2‐Iminosugar With Pharmacological Chaperone Activity for Gaucher Disease: Synthesis and Intracellular Distribution Studies

Yoshiyuki Suzuki, K. Higaki, E. Nanba, 2010, Chembiochem : a European journal of chemical biology.

Chaperone Activity of Bicyclic Nojirimycin Analogues for Gaucher Mutations in Comparison with N‐(n‐nonyl)Deoxynojirimycin

Yoshiyuki Suzuki, K. Higaki, C. Ortiz Mellet, 2009, Chembiochem : a European journal of chemical biology.

Synthesis of polyfluoroalkyl sp2-iminosugar glycolipids and evaluation of their immunomodulatory properties towards anti-tumor, anti-leishmanial and anti-inflammatory therapies.

F. Gamarro, C. Ortiz Mellet, J. G. García Fernández, 2019, European journal of medicinal chemistry.

Monodisperse nanoparticles from self-assembling amphiphilic cyclodextrins: modulable tools for the encapsulation and controlled release of pharmaceuticals.

J. Putaux, J. M. Benito, C. Ortiz Mellet, 2012, Medicinal chemistry (Shariqah (United Arab Emirates)).

Bicyclic Picomolar OGA Inhibitors Enable Chemoproteomic Mapping of Its Endogenous Post-translational Modifications.

L. Foster, G. Davies, M. González-Cuesta, 2022, Journal of the American Chemical Society.

Probing carbohydrate-lectin recognition in heterogeneous environments with monodisperse cyclodextrin-based glycoclusters.

J. L. Jiménez Blanco, J. M. Benito, C. Ortiz Mellet, 2012, The Journal of organic chemistry.

Fullerene-sp2-iminosugar balls as multimodal ligands for lectins and glycosidases: a mechanistic hypothesis for the inhibitory multivalent effect.

C. Ortiz Mellet, J. G. García Fernández, J. Nierengarten, 2013, Chemistry.

Docetaxel-Loaded Nanoparticles Assembled from β-Cyclodextrin/Calixarene Giant Surfactants: Physicochemical Properties and Cytotoxic Effect in Prostate Cancer and Glioblastoma Cells

F. Sansone, C. Ortiz Mellet, J. G. García Fernández, 2017, Front. Pharmacol..

(Pseudo)amide-linked oligosaccharide mimetics: molecular recognition and supramolecular properties

J. L. Jiménez Blanco, C. Ortiz Mellet, J. G. García Fernández, 2010, Beilstein journal of organic chemistry.

Biophysics and protein corona analysis of Janus cyclodextrin-DNA nanocomplexes. Efficient cellular transfection on cancer cells.

G. Caracciolo, J. M. Benito, C. Ortiz Mellet, 2017, Biochimica et biophysica acta. General subjects.

Amplified detection of breast cancer autoantibodies using MUC1-based Tn antigen mimics.

S. Nishimura, C. Ortiz Mellet, J. G. García Fernández, 2020, Journal of medicinal chemistry.

Synthesis of N-, S-, and C-glycoside castanospermine analogues with selective neutral alpha-glucosidase inhibitory activity as antitumour agents.

C. Ortiz Mellet, J. G. García Fernández, H. Ouadid‐Ahidouch, 2010, Chemical communications.

Di-D-fructose dianhydride-enriched caramels: effect on colon microbiota, inflammation, and tissue damage in trinitrobenzenesulfonic acid-induced colitic rats.

C. Ortiz Mellet, J. G. García Fernández, A. Zarzuelo, 2010, Journal of agricultural and food chemistry.

Preorganized, macromolecular, gene-delivery systems.

J. M. Benito, C. Ortiz Mellet, J. G. García Fernández, 2010, Chemistry.

Cyclodextrin-Based Functional Glyconanomaterials

J. M. Benito, C. Ortiz Mellet, J. G. García Fernández, 2020, Nanomaterials.

Multiply–linked cyclodextrin–aromatic hybrids: Caps, hinges and clips

J. M. Benito, C. Ortiz Mellet, J. M. Fernandez, 2019, Journal of Carbohydrate Chemistry.

Trehalose-based Janus cyclooligosaccharides: the "Click" synthesis and DNA-directed assembly into pH-sensitive transfectious nanoparticles.

J. L. Jiménez Blanco, T. Carmona, C. Ortiz Mellet, 2016, Chemical communications.

Probing secondary carbohydrate-protein interactions with highly dense cyclodextrin-centered heteroglycoclusters: the heterocluster effect.

R. Gutiérrez Gallego, J. M. Benito, C. Ortiz Mellet, 2005, Journal of the American Chemical Society.

A general entry to linear, dendritic and branched thiourea-linked glycooligomers as new motifs for phosphate ester recognition in water.

R. Gutiérrez Gallego, J. L. Jiménez Blanco, C. Ortiz Mellet, 2004, Chemical communications.

Multivalent cyclooligosaccharides: versatile carbohydrate clusters with dual role as molecular receptors and lectin ligands.

C. Ortiz Mellet, J. G. García Fernández, J. Defaye, 2002, Chemistry.

Multivalency as an action principle in multimodal lectin recognition and glycosidase inhibition: a paradigm shift driven by carbon-based glyconanomaterials.

C. Ortiz Mellet, J. G. García Fernández, J. Nierengarten, 2017, Journal of materials chemistry. B.

The Multivalent Effect in Glycosidase Inhibition: Probing the Influence of Valency, Peripheral Ligand Structure, and Topology with Cyclodextrin‐Based Iminosugar Click Clusters

C. Ortiz Mellet, P. Compain, Camille Decroocq, 2013, Chembiochem : a European journal of chemical biology.

sp2-Iminosugars targeting human lysosomal β-hexosaminidase as pharmacological chaperone candidates for late-onset Tay-Sachs disease

K. Higaki, E. Nanba, M. González-Cuesta, 2022, Journal of enzyme inhibition and medicinal chemistry.

Inhibitor versus chaperone behaviour of d-fagomine, DAB and LAB sp(2)-iminosugar conjugates against glycosidases: A structure-activity relationship study in Gaucher fibroblasts.

K. Higaki, E. Nanba, C. Ortiz Mellet, 2016, European journal of medicinal chemistry.

Conformationally-locked C-glycosides: tuning aglycone interactions for optimal chaperone behaviour in Gaucher fibroblasts.

K. Higaki, E. Nanba, C. Ortiz Mellet, 2016, Organic & biomolecular chemistry.

Conformationally-locked N-glycosides: exploiting long-range non-glycone interactions in the design of pharmacological chaperones for Gaucher disease.

Yoshiyuki Suzuki, K. Higaki, E. Nanba, 2015, European journal of medicinal chemistry.

Pharmacological Chaperones and Coenzyme Q10 Treatment Improves Mutant β-Glucocerebrosidase Activity and Mitochondrial Function in Neuronopathic Forms of Gaucher Disease

C. Ortiz Mellet, J. M. Fernandez, M. Cordero, 2015, Scientific Reports.

A bicyclic 1-deoxygalactonojirimycin derivative as a novel pharmacological chaperone for GM1 gangliosidosis.

Kei Yura, Yasubumi Sakakibara, Katsumi Higaki, 2013, Molecular therapy : the journal of the American Society of Gene Therapy.

Pharmacological Chaperones for the Treatment of α-Mannosidosis.

K. Higaki, E. Nanba, C. Ortiz Mellet, 2019, Journal of medicinal chemistry.

Targeted delivery of pharmacological chaperones for Gaucher disease to macrophages by a mannosylated cyclodextrin carrier.

Yoshiyuki Suzuki, K. Higaki, E. Nanba, 2014, Organic & biomolecular chemistry.

Stereoselective synthesis of 2-acetamido-1,2-dideoxyallonojirimycin (DAJNAc), a new potent hexosaminidase inhibitor.

A. Riera, C. Ortiz Mellet, J. G. García Fernández, 2013, Organic letters.

Synthesis and evaluation of isourea-type glycomimetics related to the indolizidine and trehazolin glycosidase inhibitor families.

C. Ortiz Mellet, J. G. García Fernández, M. I. García-Moreno, 2003, The Journal of organic chemistry.

Tuning glycosidase inhibition through aglycone interactions: pharmacological chaperones for Fabry disease and GM1 gangliosidosis.

Y. Sakakibara, K. Yura, K. Higaki, 2012, Chemical communications.

Generalized anomeric effect in action: synthesis and evaluation of stable reducing indolizidine glycomimetics as glycosidase inhibitors.

F. Cañada, C. Ortiz Mellet, J. G. García Fernández, 2000, The Journal of organic chemistry.

Multivalent glycoligands with lectin/enzyme dual specificity: self-deliverable glycosidase regulators.

K. Higaki, E. Nanba, O. Renaudet, 2019, Chemical communications.

Topological effects and binding modes operating with multivalent iminosugar-based glycoclusters and mannosidases.

C. Ortiz Mellet, S. E. Matthews, K. El Kirat, 2013, Journal of the American Chemical Society.

Functional Evaluation of Carbohydrate‐Centred Glycoclusters by Enzyme‐Linked Lectin Assay: Ligands for Concanavalin A

M. Köhn, J. M. Benito, C. Ortiz Mellet, 2004, Chembiochem : a European journal of chemical biology.

Unravelling the Inflammatory Processes in the Early Stages of Diabetic Nephropathy and the Potential Effect of (Ss)-DS-ONJ

A. Campos-Caro, C. Ortiz Mellet, J. García-Fernández, 2022, International journal of molecular sciences.

Catalyst-Free Synthesis of Alkylpolyglycosides Induced by High-Frequency Ultrasound.

D. Gigmes, C. Ortiz Mellet, J. G. García Fernández, 2018, ChemSusChem.

One-step synthesis of non-anomeric sugar isothiocyanates from sugar azides.

J. M. Benito, C. Ortiz Mellet, J. G. García Fernández, 2002, Carbohydrate research.

Synthesis of multibranched australine derivatives from reducing castanospermine analogues through the Amadori rearrangement of gem-diamine intermediates: selective inhibitors of β-glucosidase.

E. Álvarez, C. Ortiz Mellet, J. G. García Fernández, 2014, The Journal of organic chemistry.

sp2-Iminosugar glycolipids as inhibitors of lipopolysaccharide-mediated human dendritic cell activation in vitro and of acute inflammation in mice in vivo.

C. Ortiz Mellet, J. G. García Fernández, Jean-Daniel Fauny, 2019, European journal of medicinal chemistry.

Scalable syntheses of both enantiomers of DNJNAc and DGJNAc from glucuronolactone: the effect of N-alkylation on hexosaminidase inhibition.

T. Butters, C. Ortiz Mellet, J. G. García Fernández, 2012, Chemistry.

Glycoligand-targeted core-shell nanospheres with tunable drug release profiles from calixarene-cyclodextrin heterodimers.

F. Sansone, C. Ortiz Mellet, J. G. García Fernández, 2014, Chemical communications.

Iminosugar-based glycopolypeptides: glycosidase inhibition with bioinspired glycoprotein analogue micellar self-assemblies.

C. Ortiz Mellet, Colin Bonduelle, S. Lecommandoux, 2014, Chemical communications.

Fluorinated hydroxypiperidines as selective β-glucosidase inhibitors.

C. Ortiz Mellet, D. Gueyrard, T. Mena-Barragán, 2015, Organic & biomolecular chemistry.

Inhibition of type 1 fimbriae-mediated Escherichia coli adhesion and biofilm formation by trimeric cluster thiomannosides conjugated to diamond nanoparticles.

Sabine Szunerits, Rabah Boukherroub, R. Boukherroub, 2015, Nanoscale.

Di-D-fructose dianhydride-enriched products by acid ion-exchange resin-promoted caramelization of D-fructose: chemical analyses.

S. Pilard, C. Ortiz Mellet, J. G. García Fernández, 2010, Journal of agricultural and food chemistry.

Stereoselective Synthesis of Iminosugar 2-Deoxy(thio)glycosides from Bicyclic Iminoglycal Carbamates Promoted by Cerium(IV) Ammonium Nitrate and Cooperative Brønsted Acid-Type Organocatalysis.

C. Ortiz Mellet, J. G. García Fernández, C. Nativi, 2020, The Journal of organic chemistry.

Stereoselective Synthesis of Nojirimycin α-C-Glycosides from a Bicyclic Acyliminium Intermediate: A Convenient Entry to N,C-Biantennary Glycomimetics

M. González-Cuesta, C. Ortiz Mellet, J. G. García Fernández, 2022, ACS omega.

Synthesis of sp2-Iminosugar Selenoglycolipids as Multitarget Drug Candidates with Antiproliferative, Leishmanicidal and Anti-Inflammatory Properties

F. Gamarro, C. Ortiz Mellet, J. G. García Fernández, 2021, Molecules.

Influence of the configurational pattern of sp(2)-iminosugar pseudo N-, S-, O- and C-glycosides on their glycoside inhibitory and antitumor properties.

C. Ortiz Mellet, J. G. García Fernández, J. Padrón, 2016, Carbohydrate research.

o-Xylylene protecting group in carbohydrate chemistry: application to the regioselective protection of a single vic-diol segment in cyclodextrins.

J. L. Jiménez Blanco, C. Ortiz Mellet, J. G. García Fernández, 2013, The Journal of organic chemistry.

sp2-Iminosugar O-, S-, and N-glycosides as conformational mimics of α-linked disaccharides; implications for glycosidase inhibition.

J. Angulo, P. Nieto, C. Ortiz Mellet, 2012, Chemistry.

Intramolecular benzyl protection delivery: a practical synthesis of DMDP and DGDP from D-fructose.

C. Ortiz Mellet, J. G. García Fernández, M. I. García-Moreno, 2006, Organic letters.

Stereoselective synthesis of 2-acetamido-1,2-dideoxynojirimycin (DNJNAc) and ureido-DNJNAc derivatives as new hexosaminidase inhibitors.

A. Riera, C. Ortiz Mellet, J. G. García Fernández, 2015, Organic & biomolecular chemistry.

Synthesis and evaluation of sulfamide-type indolizidines as glycosidase inhibitors.

C. Ortiz Mellet, J. G. García Fernández, Mahmoud Benltifa, 2008, Bioorganic & medicinal chemistry letters.

A versatile stereocontrolled synthesis of 2-deoxyiminosugar C-glycosides and their evaluation as glycosidase inhibitors.

Aurélien Planchat, C. Ortiz Mellet, A. Lumbroso, 2020, Organic & biomolecular chemistry.

Influence of the macroring size on the self-association thermodynamics of cyclodextrins with a double-linked naphthalene at the secondary face.

J. M. Benito, C. Ortiz Mellet, F. Mendicuti, 2013, The journal of physical chemistry. B.

Glycosidase inhibition with fullerene iminosugar balls: a dramatic multivalent effect.

Philippe Compain, C. Ortiz Mellet, D. Hazelard, 2010, Angewandte Chemie.

Efficient stereoselective synthesis of 2-acetamido-1,2-dideoxyallonojirimycin (DAJNAc) and sp(2)-iminosugar conjugates: Novel hexosaminidase inhibitors with discrimination capabilities between the mature and precursor forms of the enzyme.

K. Higaki, A. Riera, E. Nanba, 2016, European journal of medicinal chemistry.

Cyclodextrin-based multivalent glycodisplays: covalent and supramolecular conjugates to assess carbohydrate-protein interactions.

C. Ortiz Mellet, J. G. García Fernández, Álvaro Martínez, 2013, Chemical Society reviews.

The multivalent effect in glycosidase inhibition: probing the influence of architectural parameters with cyclodextrin-based iminosugar click clusters.

C. Ortiz Mellet, P. Compain, Camille Decroocq, 2011, Chemistry.

Giant Glycosidase Inhibitors: First- and Second-Generation Fullerodendrimers with a Dense Iminosugar Shell.

C. Ortiz Mellet, P. Compain, J. Nierengarten, 2018, Chemistry.

Multivalent iminosugars to modulate affinity and selectivity for glycosidases.

C. Ortiz Mellet, K. Haupt, J. Kovensky, 2009, Organic & biomolecular chemistry.

Host-Guest-Mediated DNA Templation of Polycationic Supramolecules for Hierarchical Nanocondensation and the Delivery of Gene Material.

J. M. Benito, T. Carmona, C. Ortiz Mellet, 2015, Chemistry.

Carbohydrate-based receptors with multiple thiourea binding sites. Multipoint hydrogen bond recognition of dicarboxylates and monosaccharides.

J. L. Jiménez Blanco, J. M. Benito, C. Ortiz Mellet, 2001, The Journal of organic chemistry.

Optimizing saccharide-directed molecular delivery to biological receptors: design, synthesis, and biological evaluation of glycodendrimer-cyclodextrin conjugates.

J. M. Benito, C. Ortiz Mellet, J. G. García Fernández, 2004, Journal of the American Chemical Society.

Trehalose- and glucose-derived glycoamphiphiles: small-molecule and nanoparticle Toll-like receptor 4 (TLR4) modulators.

J. L. Jiménez Blanco, C. Ortiz Mellet, J. G. García Fernández, 2014, Journal of medicinal chemistry.

Cyclotrehalins: cyclooligosaccharide receptors featuring a hydrophobic cavity.

J. L. Jiménez Blanco, J. M. Benito, C. Ortiz Mellet, 2002, Angewandte Chemie.

Trehalose-based cyclodextrin analogs: cyclotrehalans (CTs)

J. L. Jiménez Blanco, J. M. Benito, C. Ortiz Mellet, 2007 .

Dynamic Control of the Self-Assembling Properties of Cyclodextrins by the Interplay of Aromatic and Host-Guest Interactions

J. M. Benito, T. Carmona, C. Przybylski, 2019, Front. Chem..

Carbohydrate supramolecular chemistry: beyond the multivalent effect.

M. González-Cuesta, C. Ortiz Mellet, J. G. García Fernández, 2020, Chemical communications.

The Impact of Heteromultivalency in Lectin Recognition and Glycosidase Inhibition: An Integrated Mechanistic Study.

C. Ortiz Mellet, J. G. García Fernández, F. Ortega-Caballero, 2017, Chemistry.

Dynamic self-assembly of polycationic clusters based on cyclodextrins for pH-sensitive DNA nanocondensation and delivery by component design.

F. Santoyo-González, J. M. Benito, C. Ortiz Mellet, 2014, Chemistry.

Size-tunable trehalose-based nanocavities: synthesis, structure, and inclusion properties of large-ring cyclotrehalans.

J. M. Benito, C. Ortiz Mellet, J. G. García Fernández, 2009, The Journal of organic chemistry.

Castanospermine-trehazolin hybrids: a new family of glycomimetics with tuneable glycosidase inhibitory properties.

C. Ortiz Mellet, J. G. García Fernández, M. I. García-Moreno, 2002, Chemical communications.

Thiol-ene "Click" Synthesis and Pharmacological Evaluation of C-Glycoside sp2-Iminosugar Glycolipids

F. Gamarro, C. Ortiz Mellet, J. G. García Fernández, 2019, Molecules.

Fluorinated Chaperone-β-Cyclodextrin Formulations for β-Glucocerebrosidase Activity Enhancement in Neuronopathic Gaucher Disease.

K. Higaki, E. Nanba, J. M. Benito, 2017, Journal of medicinal chemistry.

pH-Responsive Pharmacological Chaperones for Rescuing Mutant Glycosidases.

Yoshiyuki Suzuki, K. Higaki, E. Nanba, 2015, Angewandte Chemie.

Bicyclic Derivatives of L‐Idonojirimycin as Pharmacological Chaperones for Neuronopathic Forms of Gaucher Disease

F. Sánchez-Jiménez, C. Ortiz Mellet, J. G. García Fernández, 2013, Chembiochem : a European journal of chemical biology.

Amphiphilic 1-deoxynojirimycin derivatives through click strategies for chemical chaperoning in N370S Gaucher cells.

T. Butters, C. Ortiz Mellet, K. Haupt, 2011, The Journal of organic chemistry.

Cyclodextrin-mediated crystallization of acid β-glucosidase in complex with amphiphilic bicyclic nojirimycin analogues.

J. Sussman, I. Silman, J. M. Benito, 2011, Organic & biomolecular chemistry.

Fluorescent-tagged sp2-iminosugars with potent β-glucosidase inhibitory activity.

T. Wrodnigg, C. Ortiz Mellet, J. G. García Fernández, 2010, Bioorganic & medicinal chemistry.

Glycosidase inhibition by ring-modified castanospermine analogues: tackling enzyme selectivity by inhibitor tailoring.

J. Turkenburg, G. Davies, C. Ortiz Mellet, 2009, Organic & biomolecular chemistry.

6‐Amino‐6‐deoxy‐5,6‐di‐N‐(N′‐octyliminomethylidene)nojirimycin: Synthesis, Biological Evaluation, and Crystal Structure in Complex with Acid β‐Glucosidase

J. Sussman, I. Silman, C. Ortiz Mellet, 2009, Chembiochem : a European journal of chemical biology.

Synthesis and evaluation of calystegine B2 analogues as glycosidase inhibitors.

J. M. Benito, C. Ortiz Mellet, J. G. García Fernández, 2001, The Journal of organic chemistry.

Synthesis of glycosyl(thio)ureido sugars via carbodiimides and their conformational behaviour in water.

C. Ortiz Mellet, J. G. García Fernández, V. M. Díaz Pérez, 2000, Carbohydrate research.

Generalized anomeric effect in gem-diamines: stereoselective synthesis of alpha-N-linked disaccharide mimics.

C. Ortiz Mellet, J. G. García Fernández, M. Aguilar-Moncayo, 2009, Organic letters.

Rational design of cell active C2-modified DGJ analogues for the inhibition of human α-galactosidase A (GALA).

P. Gilormini, M. González-Cuesta, C. Ortiz Mellet, 2021, Organic & biomolecular chemistry.

Anti-Inflammatory (M2) Response Is Induced by a sp2-Iminosugar Glycolipid Sulfoxide in Diabetic Retinopathy

Á. Valverde, A. Campos-Caro, C. Ortiz Mellet, 2021, Frontiers in Immunology.

Construction of giant glycosidase inhibitors from iminosugar-substituted fullerene macromonomers.

C. Ortiz Mellet, J. G. García Fernández, P. Compain, 2017, Journal of materials chemistry. B.

Potent Glycosidase Inhibition with Heterovalent Fullerenes: Unveiling the Binding Modes Triggering Multivalent Inhibition.

C. Ortiz Mellet, J. G. García Fernández, J. Nierengarten, 2016, Chemistry.

Neuronopathic Gaucher's disease: induced pluripotent stem cells for disease modelling and testing chaperone activity of small compounds.

J. I. Izpisúa Belmonte, A. Ribes, C. Ortiz Mellet, 2013, Human molecular genetics.

Molecular Basis for β‐Glucosidase Inhibition by Ring‐Modified Calystegine Analogues

G. Davies, C. Ortiz Mellet, J. G. García Fernández, 2008, Chembiochem : a European journal of chemical biology.

Mannobioside biomimetics that trigger DC-SIGN binding selectivity.

P. Nieto, J. Rojo, F. Fieschi, 2022, Chemical Communications.

Synthesis of substituted exo-glucals via a modified Julia olefination and identification as selective β-glucosidase inhibitors.

C. Ortiz Mellet, P. Goekjian, D. Gueyrard, 2014, Organic & biomolecular chemistry.

A mild and efficient procedure to remove acetal and dithioacetal protecting groups in carbohydrate derivatives using 2,3-dichloro-5,6-dicyano-1,4-benzoquinone.

C. Ortiz Mellet, J. G. García Fernández, J. Fuentes, 1995, Carbohydrate research.

Multivalency in heterogeneous glycoenvironments: hetero-glycoclusters, -glycopolymers and -glycoassemblies.

J. L. Jiménez Blanco, C. Ortiz Mellet, J. G. García Fernández, 2013, Chemical Society reviews.

Novel Therapies for Orphan Diseases.

C. Ortiz Mellet, J. G. García Fernández, 2019, ACS medicinal chemistry letters.

Tuning the Topological Landscape of DNA-Cyclodextrin Nanocomplexes by Molecular Design.

Ana I. Carbajo‐Gordillo, J. M. Benito, C. Ortiz Mellet, 2020, Chemistry.

Carbohydrate-derived spiroketals: stereoselective synthesis of di-D-fructose dianhydrides via intramolecular aglycon delivery.

C. Ortiz Mellet, J. G. García Fernández, E. Rubio, 2003, Organic letters.

Carbohydrate-derived spiroketals. Stereoselective synthesis of di-D-fructose dianhydrides by boron trifluoride promoted glycosylation-spiroketalization of acetal precursors.

J. M. Benito, C. Ortiz Mellet, J. G. García Fernández, 2001, Organic letters.

Cyclodextrin-Based Nanostructure Efficiently Delivers siRNA to Glioblastoma Cells Preferentially via Macropinocytosis

J. L. Jiménez Blanco, C. Ortiz Mellet, J. G. García Fernández, 2020, International journal of molecular sciences.

Probing the nature of the cluster effect observed with synthetic multivalent galactosides and peanut agglutinin lectin.

C. Ortiz Mellet, J. G. García Fernández, Laura Gallego-Yerga, 2013, Chemistry.

Correlations between changes in intestinal microbiota composition and performance parameters in broiler chickens.

C. Ortiz Mellet, R. Ruiz, L. A. Rubio, 2015, Journal of animal physiology and animal nutrition.

Cholesterol-Targeted Anticancer and Apoptotic Effects of Anionic and Polycationic Amphiphilic Cyclodextrin Nanoparticles.

J. M. Benito, C. Ortiz Mellet, Gamze Varan, 2016, Journal of pharmaceutical sciences.

Effects of inulin and di-D-fructose dianhydride-enriched caramels on intestinal microbiota composition and performance of broiler chickens.

M J Peinado, A Echávarri, R Ruiz, 2013, Animal : an international journal of animal bioscience.

Trehalose-based Siamese twin amphiphiles with tunable self-assembling, DNA nanocomplexing and gene delivery properties.

Ana I. Carbajo‐Gordillo, J. L. Jiménez Blanco, J. M. Benito, 2019, Chemical communications.

Targeted gene delivery by new folate-polycationic amphiphilic cyclodextrin-DNA nanocomplexes in vitro and in vivo.

C. Ortiz Mellet, J. G. García Fernández, Koldo Urbiola, 2013, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

The o-xylylene protecting group as an element of conformational control of remote stereochemistry in the synthesis of spiroketals.

C. Ortiz Mellet, J. G. García Fernández, P. Balbuena, 2006, Chemical communications.

Rational design of cationic cyclooligosaccharides as efficient gene delivery systems.

Alejandro Díaz-Moscoso, A. Mazzaglia, N. Micali, 2008, Chemical communications.

Impact of Nonthermal Atmospheric Plasma on the Structure of Cellulose: Access to Soluble Branched Glucans.

François Jérôme, Abdellatif Barakat, Cédric Gaillard, 2016, Chemistry.

Synthesis of high-mannose oligosaccharide analogues through click chemistry: true functional mimics of their natural counterparts against lectins?

C. Ortiz Mellet, J. G. García Fernández, Alejandro Méndez‐Ardoy, 2015, Chemistry.

Plasmid-Templated Control of DNA-Cyclodextrin Nanoparticle Morphology through Molecular Vector Design for Effective Gene Delivery.

J. M. Benito, C. Ortiz Mellet, C. Tros de Ilarduya, 2018, Chemistry.

Correction to "Generalized Anomeric Effect in gem-Diamines: Stereoselective Synthesis of α-N-Linked Disaccharide Mimics".

C. Ortiz Mellet, J. G. García Fernández, M. Aguilar-Moncayo, 2016, Organic Letters.

Serine-/Cysteine-Based sp2-Iminoglycolipids as Novel TLR4 Agonists: Evaluation of Their Adjuvancy and Immunotherapeutic Properties in a Murine Model of Asthma.

M. González-Cuesta, C. Ortiz Mellet, J. G. García Fernández, 2023, Journal of medicinal chemistry.

Cyclodextrin-scaffolded glycotransporters for gene delivery

J. M. Benito, C. Ortiz Mellet, J. G. García Fernández, 2013 .

Synthesis and Comparative Glycosidase Inhibitory Properties of Reducing Castanospermine Analogues

C. Ortiz Mellet, J. G. García Fernández, M. I. García-Moreno, 2005 .

Click Synthesis of Size- and Shape-Tunable Star Polymers with Functional Macrocyclic Cores for Synergistic DNA Complexation and Delivery.

Ana I. Carbajo‐Gordillo, J. L. Jiménez Blanco, J. M. Benito, 2020, Biomacromolecules.

Reversible Light-Induced Dimerization of Secondary Face Azobenzene-Functionalized β-Cyclodextrin Derivatives

J. M. Benito, C. Ortiz Mellet, F. Mendicuti, 2023, The Journal of organic chemistry.

Synthesis and glycosidase inhibitory activity of isourea-type bicyclic sp2-iminosugars related to galactonojirimycin and allonojirimycin

C. Ortiz Mellet, J. G. García Fernández, C. O. Mellet, 2012 .