P. Legrand

发表

Nanotechnologies for Intracellular Protein Delivery: Recent Progress in Inorganic and Organic Nanocarriers

J. Devoisselle, P. Martineau, M. Morille, 2021, Advanced Therapeutics.

A comparative study of the cellular uptake, localization and phototoxicity of meta-tetra(hydroxyphenyl) chlorin encapsulated in surface-modified submicronic oil/water carriers in HT29 tumor cells.

J. Blais, O. Bourdon, P. Legrand, 2000, Journal of photochemistry and photobiology. B, Biology.

Biodistribution of meta-tetra(hydroxyphenyl)chlorin incorporated into surface-modified nanocapsules in tumor-bearing mice.

J. Blais, O. Bourdon, P. Legrand, 2002, Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.

Relationship between complement activation, cellular uptake and surface physicochemical aspects of novel PEG-modified nanocapsules.

O. Bourdon, P. Legrand, G. Barratt, 2001, Biomaterials.

Combined hydroxypropyl-beta-cyclodextrin and poly(alkylcyanoacrylate) nanoparticles intended for oral administration of saquinavir.

G. Ponchel, P. Legrand, D. Duchěne, 2001, International journal of pharmaceutics.

Polymeric nanocapsules as drug delivery systems. A review

P. Legrand, H. Fessi, G. Barratt, 1999 .

The antileishmanial properties of surface-modified, primaquine-loaded nanocapsules tested against intramacrophagic Leishmania donovani amastigotes in vitro

P. Legrand, G. Barratt, V. Mosqueira, 2001, Annals of tropical medicine and parasitology.

[Long circulating nanocapsules: interest in the treatment of severe malaria with halofantrine].

P. Legrand, G. Barratt, V. Mosqueira, 2003, Annales pharmaceutiques francaises.

Efficacy and Pharmacokinetics of Intravenous Nanocapsule Formulations of Halofantrine in Plasmodium berghei-Infected Mice

P. Legrand, G. Barratt, V. Mosqueira, 2004, Antimicrobial Agents and Chemotherapy.

Surface-modified and conventional nanocapsules as novel formulations for parenteral delivery of halofantrine.

P. Legrand, G. Barratt, V. Mosqueira, 2006, Journal of nanoscience and nanotechnology.

In vitro and in vivo biologic evaluation of long‐circulating biodegradable drug carriers loaded with the pure antiestrogen RU 58668

P. Legrand, J. Renoir, R. Gref, 2003, International journal of cancer.

Albumin-bound nanoparticles of practically water-insoluble antimalarial lead greatly enhance its efficacy.

S. Briolant, B. Pradines, F. Nepveu, 2014, International journal of pharmaceutics.

Effects of aggregation and solvent on the toxicity of amphotericin B to human erythrocytes

P. Legrand, J. Bolard, B. E. Cohen, 1992, Antimicrobial Agents and Chemotherapy.

Interaction of amphotericin B with polymeric colloids: A spectroscopic study

J. Irache, P. Legrand, G. Barratt, 1998 .

One-sided action of amphotericin B on cholesterol-containing membranes is determined by its self-association in the medium.

F. Heitz, P. Legrand, J. Bolard, 1991, Biochemistry.

Formulation, physicochemical characterization and stability study of lithium-loaded microemulsion system.

J. Devoisselle, P. Legrand, A. El Ghzaoui, 2016, International journal of pharmaceutics.

Formulation and Evaluation of SNEDDS Loaded with Original Lipophenol for the Oral Route to Prevent Dry AMD and Stragardt’s Disease

P. Brabet, P. Legrand, Céline Crauste, 2022, Pharmaceutics.

Post-production modifications of murine mesenchymal stem cell (mMSC) derived extracellular vesicles (EVs) and impact on their cellular interaction.

J. Devoisselle, J. Armengaud, J. Bertrand-Michel, 2019, Biomaterials.

Microgels of silylated HPMC as a multimodal system for drug co-encapsulation.

J. Devoisselle, Jean Martínez, P. Legrand, 2017, International journal of pharmaceutics.

Interactions between a macrophage cell line (J774A1) and surface-modified poly (D,L-lactide) nanocapsules bearing poly(ethylene glycol).

P. Legrand, G. Barratt, M. Appel, 1999, Journal of drug targeting.

Pure antiestrogen RU 58668-loaded nanospheres: morphology, cell activity and toxicity studies.

P. Legrand, J. Renoir, R. Gref, 2004, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

In Vitro Reversion of Amphotericin B Resistance in Leishmania donovani by Poloxamer 188

J. Irache, P. Legrand, G. Barratt, 2000, Antimicrobial Agents and Chemotherapy.

Modulation of nitric oxide production in RAW 264.7 cells by transforming growth factor‐beta and interleukin‐10: differential effects on free and encapsulated immunomodulator

P. Legrand, G. Barratt, M. Appel, 1997, Journal of leukocyte biology.

Poly(ε-caprolacton) nanospheres as an alternative way to reduce amphotericin B toxicity

J. Irache, A. Orecchioni, C. Gamazo, 1997 .

Liposomal amphotericin B bases of therapeutic index increase.

P. Legrand, J. Bolard, A. Vertut-Doï, 1993, Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology.

Biodistribution of Long-Circulating PEG-Grafted Nanocapsules in Mice: Effects of PEG Chain Length and Density

Michel Vert, Ruxandra Gref, M. Vert, 2001, Pharmaceutical Research.

Poly(D,L-lactide) nanocapsules prepared by a solvent displacement process: influence of the composition on physicochemical and structural properties.

P. Legrand, G. Barratt, V. Mosqueira, 2000, Journal of pharmaceutical sciences.

Nanoparticles loaded with ferrocenyl tamoxifen derivatives for breast cancer treatment.

A. Vessières, G. Jaouen, P. Pigeon, 2008, International journal of pharmaceutics.

Phase behavior of reverse microemulsions based on Peceol(®).

J. Devoisselle, P. Legrand, O. Diat, 2014, Journal of colloid and interface science.

Polymeric carriers for amphotericin B: in vitro activity, toxicity and therapeutic efficacy against systemic candidiasis in neutropenic mice.

J. Irache, C. Gamazo, P. Legrand, 2003, The Journal of antimicrobial chemotherapy.

Skin Localization of Cow’s Milk Proteins Delivered by a New Ready-to-Use Atopy Patch Test

G. Ponchel, P. Legrand, G. Barratt, 2005, Pharmaceutical Research.

Macrophage Activation by a Lipophilic Derivative of Muramyldipeptide within Nanocapsules: Investigation of the Mechanism of Drug Delivery

P. Legrand, G. Barratt, M. Appel, 1999 .

Biological assays for plant viruses and other graft-transmissible pathogens diagnoses: a review

P. Legrand, 2015 .

Release of amphotericin B from delivery systems and its action against fungal and mammalian cells.

P. Legrand, J. Bolard, M. Chéron, 1997, Journal of drug targeting.

Development of pharmaceutical clear gel based on Peceol®, lecithin, ethanol and water: Physicochemical characterization and stability study.

J. Devoisselle, P. Legrand, O. Diat, 2015, Journal of colloid and interface science.

Water solubilization capacity of pharmaceutical microemulsions based on Peceol®, lecithin and ethanol.

J. Devoisselle, D. Lerner, P. Legrand, 2014, International journal of pharmaceutics.

Comparative internalization and recycling of different amphotericin B formulations by a macrophage-like cell line.

P. Legrand, J. Bolard, A. Vertut-Doi, 1996, The Journal of antimicrobial chemotherapy.

Reduction of NO Synthase Expression and Tumor Necrosis Factor Alpha Production in Macrophages by Amphotericin B Lipid Carriers

P. Legrand, G. Barratt, M. Appel, 2001, Antimicrobial Agents and Chemotherapy.

A morphological study of an amphotericin B emulsion-based delivery system

P. Legrand, H. Fessi, G. Barratt, 1996 .

Toxicity and Antileishmanial Activity of a New Stable Lipid Suspension of Amphotericin B

V. Yardley, S. Croft, P. Legrand, 2003, Antimicrobial Agents and Chemotherapy.

New lipid formulation of amphotericin B: spectral and microscopic analysis.

P. Legrand, G. Barratt, A. Gulik, 2004, Biochimica et biophysica acta.

In vitro antileishmanial activity of amphotericin B loaded in poly(epsilon-caprolactone) nanospheres.

J. Irache, P. Legrand, G. Barratt, 2002, Journal of drug targeting.

Interaction of amphotericin B with polymeric colloids: 2. Effect of poloxamer on the adsorption of amphotericin B onto poly(ϵ-caprolactone) nanospheres

J. Irache, P. Legrand, G. Barratt, 1998 .

Physicochemical characterization of molecular assemblies of miltefosine and amphotericin B.

S. Lesieur, P. Legrand, G. Barratt, 2007, Molecular pharmaceutics.

Comparison of the efficacy and pharmacology of formulations of amphotericin B used in treatment of leishmaniasis

P. Legrand, G. Barratt, 2005, Current opinion in infectious diseases.

Ordovician cold water brachiopods from the Ougarta Mountain Range, Algerian Sahara

P. Legrand, L. Popov, M. Pour, 2019, Bulletin of Geosciences.

A comparison of different methods for the identification of genets of Armillaria spp.

James B. Anderson, P. Legrand, J. Guillaumin, 1996, The New phytologist.

Polymeric Micro- and Nanoparticles as Drug Carriers

P. Couvreur, G. Ponchel, P. Legrand, 2001 .

Occurrence of genets of Armillaria spp. in four mountain forests in Central France: the colonization strategy of Armillaria ostoyae.

P. Legrand, J. Guillaumin, S. Ghahari, 1996, The New phytologist.

Armillaria species in the forest ecosystems of the Auvergne (Central France)

P. Legrand, J. Guillaumin, 1993 .

Interest of extracellular vesicles in regards to lipid nanoparticle based systems for intracellular protein delivery.

J. Devoisselle, P. Martineau, M. Morille, 2021, Advanced drug delivery reviews.

Nanocapsule technology: a review.

Elias Fattal, Christine Vauthier, Patrick Couvreur, 2002, Critical reviews in therapeutic drug carrier systems.

Polyester-Poly(Ethylene Glycol) Nanoparticles Loaded with the Pure Antiestrogen RU 58668: Physicochemical and Opsonization Properties

P. Legrand, G. Barratt, J. Renoir, 2003, Pharmaceutical Research.

New solid lipid microparticles for controlled ibuprofen release: formulation and characterization study.

J. Devoisselle, F. Quignard, P. Legrand, 2012, International journal of pharmaceutics.

Fossil wood from alluvial deposits (reworked Oligocene) of Limagne at Bussières (Puy-de-Dôme, France)

P. Legrand, C. Privé-Gill, Nathanaël Cao, 2008 .

Modo de desarrollo del Suborden Diplograptina (Graptolithina) en el Ordovícico Superior y en el Silúrico. Implicaciones Taxonómicas

P. Legrand, 2022, Spanish Journal of Palaeontology.

Faunal specificity, endemism and paleobiogeography: the post-glacial (Hirnantian-early Rhuddanian) graptolite fauna of the North-African border of Gondwana: a case study

P. Legrand, 2009 .

Late Ordovician-early Silurian paleogeography of the Algerian Sahara

P. Legrand, 2003 .

Direction of deoxyribonucleic acid transfer and replication in a derivative of plasmid R100-1

P. Legrand, J. Bouché, J. Louarn, 1979, Journal of bacteriology.

Drug delivery systems for oestrogenic hormones and antagonists: the need for selective targeting in estradiol-dependent cancers

P. Legrand, J. Renoir, V. Marsaud, 2004, The Journal of Steroid Biochemistry and Molecular Biology.

Simultaneous control of flotation and release kinetics from clay- containing pellets designed for oral delivery of some trace elements

G. Ponchel, P. Legrand, N. Yagoubi, 2008 .

Phytophthora disease of alder (Alnus glutinosa) in France: investigations between 1995 and 1999

P. Legrand, J. Streito, F. Tabary, 2002 .

Influence of polymer behaviour in organic solution on the production of polylactide nanoparticles by nanoprecipitation.

S. Lesieur, P. Legrand, G. Barratt, 2007, International journal of pharmaceutics.

Genetic variability in wild cherry populations in France. Effects of colonizing processes

N. Machon, D. Taneyhill, N. Frascaria-Lacoste, 1997, Theoretical and Applied Genetics.

Sea level and faunal change during the late Wenlock and earliest Ludlow (Silurian): A point of view from the Algerian Sahara

P. Legrand, 1994 .

Description de Westonia chudeaui nov. sp., brachiopode inarticule de l'Adrar mauritanien (Sahara occidental)

P. Legrand, 1969 .

Phytosanitary management of Citrus germplasm in France

P. Legrand, 2019, EPPO Bulletin.

Relationship between NO-synthase activity and TNF-alpha secretion in mouse macrophage lines stimulated by a muramyl peptide entrapped in nanocapsules.

P. Legrand, G. Barratt, M. Appel, 1996, International journal of immunopharmacology.

The lower Silurian graptolites of Oued In Djerane: a study of populations at the Ordovician-Silurian boundary

P. Legrand, 1986, Geological Society, London, Special Publications.

In Vitro Antileishmanial Activity of Amphotericin B Loaded in Poly(ε-Caprolactone) Nanospheres

J. Irache, P. Legrand, G. Barratt, 2002 .

The Terminus of Chromosome Replication of E. coli Phenotypic Suppression of a dnaA Mutation by Plasmid Integration near terC

P. Legrand, J. Louarn, J. Louarn, 1983 .