M. Gack

发表

The US3 Kinase of Herpes Simplex Virus Phosphorylates the RNA Sensor RIG-I To Suppress Innate Immunity

D. Knipe, Michiel van Gent, Jessica J. Chiang, 2021, Journal of virology.

Multimodal Single-Cell Omics Analysis of COVID-19 Sex Differences in Human Immune Systems

F. Cheng, Yadi Zhou, R. Mehra, 2020, bioRxiv.

Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I.

S. Inoue, R. Albrecht, A. García-Sastre, 2009, Cell host & microbe.

Viral evasion of intracellular DNA and RNA sensing

M. Gack, Y. Chan, Michaela U. Gack, 2016, Nature Reviews Microbiology.

TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

Osamu Takeuchi, Chengyu Liang, Shizuo Akira, 2007, Nature.

A network medicine approach to investigation and population-based validation of disease manifestations and drug repurposing for COVID-19

F. Cheng, Yadi Zhou, R. Mehra, 2020, PLoS biology.

Zika Virus NS3 Mimics a Cellular 14-3-3-Binding Motif to Antagonize RIG-I- and MDA5-Mediated Innate Immunity.

M. Diamond, C. Chiang, M. Gack, 2019, Cell host & microbe.

Viral pathogenesis: Dengue virus takes on cGAS

M. Gack, M. V. Gent, Michaela U. Gack, 2017, Nature Microbiology.

Innate immune escape by Dengue and West Nile viruses.

M. Diamond, M. Gack, Michaela U. Gack, 2016, Current opinion in virology.

Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway

B. Sankaran, Jessica J. Chiang, M. Gack, 2016, Cell reports.

Lawrence Berkeley National Laboratory Recent Work Title Mechanism of TRIM 25 Catalytic Activation in the Antiviral RIGI Pathway Permalink

B. Sankaran, Jessica J. Chiang, M. Gack, 2016 .

The shear effort of measurement of portal hypertension

M. Gack, T. Baumert, Michaela U. Gack, 2014, Hepatology.

The Human Papillomavirus E6 Oncoprotein Targets USP15 and TRIM25 To Suppress RIG-I-Mediated Innate Immune Signaling

K. Münger, P. Howley, C. Meyers, 2017, Journal of Virology.

ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity

Michiel van Gent, Jessica J. Chiang, C. Chiang, 2021, Nature Microbiology.

ISG15-dependent Activation of the RNA Sensor MDA5 and its Antagonism by the SARS-CoV-2 papain-like protease

Michiel van Gent, Jessica J. Chiang, C. Chiang, 2020, bioRxiv.

Species-Specific Inhibition of RIG-I Ubiquitination and IFN Induction by the Influenza A Virus NS1 Protein

R. Albrecht, A. García-Sastre, Gijs A Versteeg, 2012, PLoS pathogens.

A Network Medicine Approach to Investigation and Population-based Validation of Disease Manifestations and Drug Repurposing for COVID-19

F. Cheng, Yadi Zhou, R. Mehra, 2020, ChemRxiv : the preprint server for chemistry.

Conventional Protein Kinase C-α (PKC-α) and PKC-β Negatively Regulate RIG-I Antiviral Signal Transduction

M. Gack, Michaela U. Gack, A. Stoll, 2011, Journal of Virology.

Phosphorylation-Mediated Negative Regulation of RIG-I Antiviral Activity

A. García-Sastre, Jae U. Jung, M. Gack, 2010, Journal of Virology.

Identification of a second binding site on the TRIM25 B30.2 domain.

Laura F. Dagley, S. Masters, Jessica J. Chiang, 2017, The Biochemical journal.

TRIM23 mediates virus-induced autophagy via activation of TBK1

J. Moss, J. Kato, M. Vaughan, 2017, Nature Microbiology.

Viral Evasion of RIG-I-Like Receptor-Mediated Immunity through Dysregulation of Ubiquitination and ISGylation

C. Chiang, M. Gack, Guanqun Liu, 2021, Viruses.

FBXO38 Drives PD-1 to Destruction.

M. Gack, Michaela U. Gack, Taryn M. Serman, 2019, Trends in immunology.

The Small t Antigen of JC Virus Antagonizes RIG-I-Mediated Innate Immunity by Inhibiting TRIM25’s RNA Binding Ability

Jessica J. Chiang, C. Chiang, M. Gack, 2021, mBio.

The Ubiquitin-Specific Protease USP15 Promotes RIG-I–Mediated Antiviral Signaling by Deubiquitylating TRIM25

M. Gack, Y. Chan, E. Pauli, 2014, Science Signaling.

Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction

T. Ha, S. Myong, Jae U. Jung, 2008, Proceedings of the National Academy of Sciences.

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1

Mark R. Marten, Erinna F. Lee, Dana L. Miller, 2021, Autophagy.

Dysregulation of type I interferon responses in COVID-19

M. Gack, D. Acharya, Guanqun Liu, 2020, Nature Reviews Immunology.

TRIM proteins: New players in virus-induced autophagy

M. Gack, Konstantin M. J. Sparrer, Michaela U. Gack, 2018, PLoS pathogens.

Actin cytoskeleton remodeling primes RIG-I-like receptor activation

F. Kirchhoff, J. Münch, M. Gack, 2022, Cell.

Insights into pandemic respiratory viruses: manipulation of the antiviral interferon response by SARS-CoV-2 and influenza A virus

M. Gack, Guanqun Liu, Michaela U. Gack, 2022, Current Opinion in Immunology.

SARS-CoV-2 learned the ‘Alpha’bet of immune evasion

M. Gack, Guanqun Liu, Michaela U. Gack, 2022, Nature Immunology.

Viral Anti-CRISPR Tactics: No Success without Sacrifice.

Michiel van Gent, M. Gack, Michaela U. Gack, 2018, Immunity.

Role of spike in the pathogenic and antigenic behavior of SARS-CoV-2 BA.1

A. Ensser, D. Kotton, M. Gack, 2022 .