Sacha Javor

发表

Fluorescent Peptide Dendrimers for siRNA Transfection: Tracking pH Responsive Aggregation, siRNA Binding and Cell Penetration.

J. Reymond, M. Heitz, Susanna Zamolo, 2020, Bioconjugate chemistry.

Chemical space guided discovery of antimicrobial bridged bicyclic peptides against Pseudomonas aeruginosa and its biofilms

A. Stocker, J. Reymond, S. Doglia, 2017, Chemical science.

Deep cavitand vesicles--multicompartmental hosts.

J. Rebek, Sacha Javor, Jens Kubitschke, 2012, Chemical communications.

Optimizing Antimicrobial Peptide Dendrimers in Chemical Space

J. Reymond, Sacha Javor, Xian Jin, 2018, Angewandte Chemie.

Optimizing Antimicrobial Peptide Dendrimers in Chemical Space.

J. Reymond, Sacha Javor, C. van Delden, 2018, Angewandte Chemie.

An antimicrobial bicyclic peptide from chemical space against multidrug resistant Gram-negative bacteria.

J. Reymond, Sacha Javor, C. van Delden, 2018, Chemical communications.

Targeting botulinum A cellular toxicity: a prodrug approach.

K. Janda, Eric A. Johnson, Sacha Javor, 2013, Journal of medicinal chemistry.

Synergistic Effect of Propidium Iodide and Small Molecule Antibiotics with the Antimicrobial Peptide Dendrimer G3KL against Gram-Negative Bacteria

J. Reymond, Sacha Javor, B. Gan, 2020, Molecules.

Onchocerca volvulus Molting Inhibitors Identified through Scaffold Hopping.

K. Janda, Sacha Javor, S. Lustigman, 2015, ACS infectious diseases.

A mixed chirality α-helix in a stapled bicyclic and a linear antimicrobial peptide revealed by X-ray crystallography

A. Stocker, J. Reymond, Sacha Javor, 2021, RSC chemical biology.

The C6H6 NMR repository: An integral solution to control the flow of your data from the magnet to the public

Andrés M. Castillo, S. Kuhn, Norman Pellet, 2018, Magnetic resonance in chemistry : MRC.

Stereorandomization as a Method to Probe Peptide Bioactivity

J. Reymond, Sacha Javor, C. van Delden, 2020, ACS central science.

X‐Ray Crystal Structure of a Second‐Generation Peptide Dendrimer in Complex with Pseudomonas aeruginosa Lectin LecB

A. Stocker, J. Reymond, Sacha Javor, 2019, Helvetica Chimica Acta.

X-ray Crystal Structures of Short Antimicrobial Peptides as Pseudomonas aeruginosa Lectin B Complexes.

A. Stocker, J. Reymond, Sacha Javor, 2019, ACS chemical biology.

Fluorescence Imaging of Bacterial Killing by Antimicrobial Peptide Dendrimer G3KL.

J. Reymond, Sacha Javor, T. Darbre, 2019, ACS infectious diseases.

Activation of a water-soluble resorcinarene cavitand at the water-phosphocholine micelle interface.

J. Rebek, Sacha Javor, 2011, Journal of the American Chemical Society.

The antibacterial activity of peptide dendrimers and polymyxin B increases sharply above pH 7.4†

J. Reymond, Sacha Javor, B. Gan, 2021, Chemical communications.

Novel Human Butyrylcholinesterase Variants: Toward Organophosphonate Detoxication

Emily M. Smith, M. Dwyer, J. Cashman, 2014, Biochemistry.

Probing BoNT/A Protease Exosites: Implications for Inhibitor Design and Light Chain Longevity

K. Janda, Sacha Javor, M. Hixon, 2014, Biochemistry.

Synergistic E ﬀ ect of Propidium Iodide and Small Molecule Antibiotics with the Antimicrobial Peptide Dendrimer G3KL against Gram-Negative Bacteria

J. Reymond, Sacha Javor, B. Gan, 2022 .

Antimicrobial Peptide Dendrimer Chimera

J. Reymond, Sacha Javor, T. Köhler, 2019, Helvetica Chimica Acta.

Structure–Activity Relationship Studies in Single-Site Esterase Peptide Dendrimers

J. Reymond, Sacha Javor, 2009 .

Alpha-helix stabilization within a peptide dendrimer.

J. Reymond, S. Doglia, A. Natalello, 2008, Journal of the American Chemical Society.

Stereoselective pH Responsive Peptide Dendrimers for siRNA Transfection.

J. Reymond, M. Heitz, Sacha Javor, 2019, Bioconjugate chemistry.

Structure‐Based Design and Synthesis of a Small Molecule that Exhibits Anti‐inflammatory Activity by Inhibition of MyD88‐mediated Signaling to Bacterial Toxin Exposure

J. Rebek, D. Waag, Sacha Javor, 2015, Chemical biology & drug design.

Molecular dynamics and docking studies of single site esterase peptide dendrimers.

J. Reymond, Sacha Javor, 2009, The Journal of organic chemistry.

A peptide dendrimer enzyme model with a single catalytic site at the core.

J. Reymond, Sacha Javor, T. Darbre, 2007, Journal of the American Chemical Society.

An intrinsically disordered antimicrobial peptide dendrimer from stereorandomized virtual screening

J. Reymond, Sacha Javor, C. van Delden, 2022, Cell Reports. Physical Science.

Lipidated Peptide Dendrimers Killing Multidrug-Resistant Bacteria.

Jean-Louis Reymond, Thilo Köhler, Sacha Javor, 2018, Journal of the American Chemical Society.

Exploiting the Polypharmacology of ß-Carbolines to Disrupt O. volvulus Molting.

K. Janda, Sacha Javor, S. Lustigman, 2015, ACS medicinal chemistry letters.

The C-terminus of Botulinum A Protease Has Profound and Unanticipated Kinetic Consequences Upon the Catalytic Cleft.

Matthew A. Lardy, K. Janda, C. Shoemaker, 2013, ACS medicinal chemistry letters.

Dipropylamine for 9-Fluorenylmethyloxycarbonyl (Fmoc) Deprotection with Reduced Aspartimide Formation in Solid-Phase Peptide Synthesis

J. Reymond, Sacha Javor, Thissa N. Siriwardena, 2023, ACS Omega.

An Immunomodulatory Peptide Dendrimer Inspired from Glatiramer Acetate

J. Reymond, Sacha Javor, A. Capecchi, 2021, Angewandte Chemie.

Formylated polyamines as peptidomimetics.

A. Janowsky, J. Rebek, Sacha Javor, 2012, Bioorganic & medicinal chemistry letters.

Inhibitors of Human Divalent Metal Transporters DMT1 (SLC11A2) and ZIP8 (SLC39A8) from a GDB‐17 Fragment Library

J. Reymond, M. Hediger, M. Awale, 2021, ChemMedChem.

Overcoming Protein Orientation Mismatch Enables Efficient Nanoscale Light-Driven ATP Production

J. Reymond, Sacha Javor, Sabina Deutschmann, 2024, ACS synthetic biology.

To Fold or Not to Fold: Diastereomeric Optimization of an α-Helical Antimicrobial Peptide

A. Stocker, J. Reymond, Sacha Javor, 2023, Journal of medicinal chemistry.