C. Alvira

发表

Nanoparticle Delivery of Angiogenic Gene Therapy. Save the Vessels, Save the Lung!

J. Zepp, C. Alvira, 2020, American journal of respiratory and critical care medicine.

β1-Subunit of the calcium-sensitive potassium channel modulates the pulmonary vascular smooth muscle cell response to hypoxia.

D. Cornfield, E. A. Barnes, C. Alvira, 2018, American journal of physiology. Lung cellular and molecular physiology.

Pulmonary artery smooth muscle cell HIF-1α regulates endothelin expression via microRNA-543.

D. Cornfield, E. A. Barnes, C. Alvira, 2018, American journal of physiology. Lung cellular and molecular physiology.

Hypoxia-Inducible Factor-1&agr; in Pulmonary Artery Smooth Muscle Cells Lowers Vascular Tone by Decreasing Myosin Light Chain Phosphorylation

D. Cornfield, E. A. Barnes, C. Alvira, 2013, Circulation research.

Disrupted lung development and bronchopulmonary dysplasia: opportunities for lung repair and regeneration

C. Alvira, C. Baker, 2014, Current opinion in pediatrics.

Form and function: diverse homeostatic and immunomodulatory roles of immune cells in the developing lung revealed at single cell resolution

Robert C. Jones, S. Quake, D. Cornfield, 2020 .

miR-29b Participates in Early Aneurysm Development in Marfan Syndrome

P. Tsao, G. Berry, F. Mohr, 2012, Circulation research.

Biomarkers in Lung Diseases : From Pathogenesis to Prediction to New Therapies Absence of TNF-enhances inflammatory response in the newborn lung undergoing mechanical ventilation

C. Alvira, H. Ehrhardt, A. Hilgendorff, 2016 .

Prolonged mechanical ventilation with air induces apoptosis and causes failure of alveolar septation and angiogenesis in lungs of newborn mice.

R. Ertsey, C. Alvira, M. Rabinovitch, 2010, American journal of physiology. Lung cellular and molecular physiology.

Enhanced Caspase Activity Contributes to Aortic Wall Remodeling and Early Aneurysm Development in a Murine Model of Marfan Syndrome

F. Blankenberg, F. Mohr, A. Connolly, 2015, Arteriosclerosis, thrombosis, and vascular biology.

SM22α cell specific HIF stabilization mitigates hyperoxia-induced neonatal lung injury.

D. Cornfield, C. Alvira, X. Che, 2022, American journal of physiology. Lung cellular and molecular physiology.

Pulmonary artery smooth muscle cell endothelin-1 expression modulates the pulmonary vascular response to chronic hypoxia.

D. Cornfield, C. Alvira, L. Ying, 2015, American journal of physiology. Lung cellular and molecular physiology.

Chronic lung disease in the preterm infant. Lessons learned from animal models.

O. Eickelberg, C. Alvira, H. Ehrhardt, 2013, American journal of respiratory cell and molecular biology.

Voltage-dependent anion channel-2 interaction with nitric oxide synthase enhances pulmonary artery endothelial cell nitric oxide production.

D. Cornfield, Yan-li Hou, C. Alvira, 2012, American journal of respiratory cell and molecular biology.

Neutrophil elastase is produced by pulmonary artery smooth muscle cells and is linked to neointimal lesions.

C. Alvira, M. Rabinovitch, E. Spiekerkoetter, 2011, The American journal of pathology.

An antiproliferative BMP-2/PPARgamma/apoE axis in human and murine SMCs and its role in pulmonary hypertension.

G. Hansmann, N. Morrell, C. Alvira, 2008, The Journal of clinical investigation.

Tie2-mediated loss of peroxisome proliferator-activated receptor- (cid:1) in mice causes PDGF receptor- (cid:2) -dependent pulmonary arterial muscularization

G. Hansmann, C. Alvira, M. Rabinovitch, 2009 .

Tie2-mediated loss of peroxisome proliferator-activated receptor-gamma in mice causes PDGF receptor-beta-dependent pulmonary arterial muscularization.

G. Hansmann, C. Alvira, M. Rabinovitch, 2009, American journal of physiology. Lung cellular and molecular physiology.

Developmental differences in focal adhesion kinase expression modulate pulmonary endothelial barrier function in response to inflammation.

D. Cornfield, C. Alvira, L. Ying, 2018, American journal of physiology. Lung cellular and molecular physiology.

angiogenesis and alveolarization B in the developing lung disrupts κ Inhibiting NF

D. Cornfield, C. Alvira, S. Lyu, 2012 .

Reactivation of gammaHV68 induces neointimal lesions in pulmonary arteries of S100A4/Mts1-overexpressing mice in association with degradation of elastin.

N. Ambartsumian, C. Alvira, M. Rabinovitch, 2008, American journal of physiology. Lung cellular and molecular physiology.

Reactivation of HV 68 induces neointimal lesions in pulmonary arteries of S 100 A 4 / Mts 1-overexpressing mice in association with degradation of elastin

N. Ambartsumian, C. Alvira, M. Rabinovitch, 2008 .

Activation of the nuclear factor-κB pathway during postnatal lung inflammation preserves alveolarization by suppressing macrophage inflammatory protein-2.

Yan-li Hou, C. Alvira, J. Johns, 2015, American journal of physiology. Lung cellular and molecular physiology.

Inhibiting NF-κB in the developing lung disrupts angiogenesis and alveolarization.

D. Cornfield, Yan-li Hou, C. Alvira, 2012, American journal of physiology. Lung cellular and molecular physiology.

Nuclear factor-kappaB activation in neonatal mouse lung protects against lipopolysaccharide-induced inflammation.

C. Alvira, P. Dennery, M. Rabinovitch, 2007, American journal of respiratory and critical care medicine.

Mechanical ventilation uncouples synthesis and assembly of elastin and increases apoptosis in lungs of newborn mice. Prelude to defective alveolar septation during lung development?

R. Ertsey, C. Alvira, M. Rabinovitch, 2008, American journal of physiology. Lung cellular and molecular physiology.

Dynamism of the Human Lung Proteome during Alveolarization: Moving beyond the Transcriptome

C. Alvira, 2021, American journal of respiratory and critical care medicine.

Rho kinase modulates postnatal adaptation of the pulmonary circulation through separate effects on pulmonary artery endothelial and smooth muscle cells.

D. Cornfield, C. Alvira, David Sukovich, 2010, American journal of physiology. Lung cellular and molecular physiology.

MATERIALS AND METHODS All procedures and protocols performed in this study conformed with the Guide for the Care and Use of Laboratory Animals

D. Cornfield, C. Alvira, David Sukovich, 2010 .

Progressive Increases in Mesenchymal Cell Diversity Modulate Lung Development and are Attenuated by Hyperoxia

Robert C. Jones, S. Quake, D. Cornfield, 2021 .

Can We Understand the Pathobiology of Bronchopulmonary Dysplasia?

R. Morty, C. Alvira, 2017, The Journal of pediatrics.

Disruption of Essential Developmental Pathways Impaired and Dysmorphic Pulmonary Vascular Growth

R. Morty, C. Alvira, 2017 .

Developmental Expression of Transforming Growth Factor Induced Protein Promotes NF-Kappa-B Mediated Angiogenesis During Postnatal Lung Development

K. Albertine, C. Alvira, S. Heilshorn, 2020, bioRxiv.

Phenotypic diversity and sensitivity to injury of the pulmonary endothelium during a period of rapid postnatal growth

Robert C. Jones, S. Quake, D. Cornfield, 2021 .

NF‐κB/NKILA signaling modulates the anti‐cancerous effects of EZH2 inhibition

C. Alvira, I. Buxton, C. Iosef, 2019, Journal of cellular and molecular medicine.

Lung mesenchymal cell diversity rapidly increases at birth and is profoundly altered by hyperoxia

Robert C. Jones, S. Quake, D. Cornfield, 2023, bioRxiv.

Transforming Growth Factor Induced Protein Promotes NF-Kappa-B Mediated Angiogenesis During Postnatal Lung Development.

K. Albertine, C. Alvira, S. Heilshorn, 2020, American journal of respiratory cell and molecular biology.

Developmental diversity and unique sensitivity to injury of lung endothelial subtypes during a period of rapid postnatal growth

Robert C. Jones, S. Quake, D. Cornfield, 2022, bioRxiv.

Macrophage-derived IL-6 trans-signalling as a novel target in the pathogenesis of bronchopulmonary dysplasia

P. Khatri, W. Seeger, M. Odenthal, 2021, European Respiratory Journal.

Diverse homeostatic and immunomodulatory roles of immune cells in the developing mouse lung at single cell resolution

Robert C. Jones, S. Quake, D. Cornfield, 2020, eLife.

Inhibition of transforming growth factor β worsens elastin degradation in a murine model of Kawasaki disease.

Dean Y. Li, R. Yeung, C. Alvira, 2011, The American journal of pathology.

Enhancing the Development and Retention of Physician-Scientists in Academic Pediatrics: Strategies for Success.

J. Padbury, C. Alvira, S. Abman, 2018, The Journal of pediatrics.

Aberrant Pulmonary Vascular Growth and Remodeling in Bronchopulmonary Dysplasia

C. Alvira, 2016, Front. Med..

Nuclear Factor-Kappa-B Signaling in Lung Development and Disease: One Pathway, Numerous Functions

C. Alvira, Cristina M Alvira, 2014, Birth defects research. Part A, Clinical and molecular teratology.

Hypoxia-inducible factor-1α regulates KCNMB1 expression in human pulmonary artery smooth muscle cells.

D. Cornfield, Y. Ahn, C. Alvira, 2012, American journal of physiology. Lung cellular and molecular physiology.

Hypoxia-inducible factor-1 regulates KCNMB 1 expression in human pulmonary artery smooth muscle cells

D. Cornfield, Y. Ahn, C. Alvira, 2012 .

Loss of PPARγ in endothelial cells leads to impaired angiogenesis

C. Alvira, J. Koskenvuo, M. Rabinovitch, 2016, Journal of Cell Science.

Developmental diversity and unique sensitivity to injury of lung endothelial subtypes during postnatal growth

Robert C. Jones, S. Quake, D. Cornfield, 2023, iScience.

Haemophagocytic lymphohistiocytosis associated with coccidiomycosis

D. Cornfield, C. Alvira, P. Purohit, 2014, BMJ Case Reports.

The transient receptor potential vanilloid 4 channel modulates uterine tone during pregnancy

D. Cornfield, D. Lyell, Xiaoyuan Han, 2015, Science Translational Medicine.

Hypoxia-Inducible Factor-1 α in Pulmonary Artery Smooth Muscle Cells Lowers Vascular Tone by Decreasing Myosin Light Chain Phosphorylation Short Communication

D. Cornfield, C. Alvira, E. Barnes, 2013 .

Distinct roles for IκB kinases alpha and beta in regulating pulmonary endothelial angiogenic function during late lung development

C. Alvira, L. Ying, Shailaja P Rao, 2018, Journal of cellular and molecular medicine.

LC3-mediated fibronectin mRNA translation induces fibrosarcoma growth by increasing connective tissue growth factor

R. West, M. van de Rijn, P. Sarnow, 2009, Journal of Cell Science.

Long‐term miR‐29b suppression reduces aneurysm formation in a Marfan mouse model

A. Connolly, C. Alvira, M. Fischbein, 2017, Physiological reports.

Intrauterine growth restriction decreases NF-κB signaling in fetal pulmonary artery endothelial cells of fetal sheep.

T. Crombleholme, D. Astling, P. Rozance, 2018, American journal of physiology. Lung cellular and molecular physiology.

Inhibiting NF-κB in the developing lung disrupts angiogenesis and alveolarization.

D. Cornfield, C. Alvira, S. Lyu, 2012, American journal of physiology. Lung cellular and molecular physiology.

Pulmonary artery smooth muscle cell endothelin-1 expression modulates the pulmonary vascular response to chronic hypoxia.

D. Cornfield, C. Alvira, L. Ying, 2015, American journal of physiology. Lung cellular and molecular physiology.

Tie2-mediated loss of peroxisome proliferator-activated receptor- (cid:1) in mice causes PDGF receptor- (cid:2) -dependent pulmonary arterial muscularization

G. Hansmann, C. Alvira, M. Rabinovitch, 2009 .

Tie2-mediated loss of peroxisome proliferator-activated receptor- (cid:1) in mice causes PDGF receptor- (cid:2) -dependent pulmonary arterial muscularization

C. Alvira, C. Guignabert, N. El-Bizri, 2009 .

Author response: Diverse homeostatic and immunomodulatory roles of immune cells in the developing mouse lung at single cell resolution

Robert C. Jones, S. Quake, D. Cornfield, 2020 .

Inhibition of transforming growth factor β worsens elastin degradation in a murine model of Kawasaki disease.

R. Yeung, C. Alvira, M. Rabinovitch, 2011, The American journal of pathology.

CXCL10 deficiency limits macrophage infiltration, preserves lung matrix, and enables lung growth in bronchopulmonary dysplasia

R. Savai, G. Pryhuber, C. Alvira, 2023, Inflammation and Regeneration.

Hyperoxia prevents the dynamic neonatal increases in lung mesenchymal cell diversity

Robert C. Jones, C. Alvira, Racquel Domingo-Gonzalez, 2024, Scientific reports.

Integrative analysis of noncoding mutations identifies the druggable genome in preterm birth

C. Quaintance, C. Alvira, Y. Wang, 2024, Science advances.

Voltage-dependent anion channel-2 interaction with nitric oxide synthase enhances pulmonary artery endothelial cell nitric oxide production.

D. Cornfield, C. Alvira, L. Ying, 2012, American journal of respiratory cell and molecular biology.

Hypoxia Inducible Factor-1α in SM22α Expressing Cells Modulates Alveolarization.

D. Cornfield, Alida Kindt, C. Alvira, 2023, American journal of respiratory cell and molecular biology.

Pulmonary artery smooth muscle cell HIF-1 (cid:2) regulates endothelin expression via microRNA-543

C. Alvira, L. Ying, Eloa S. Adams, 2018 .